2011 YÜksek lisans tez özetleri

Molecular, Biochemical Analysis and Differantiation of Stem Cells Derived from Cord Blood
The concept of stem cell has found a wide application due to creating a glimmer of hope at wide spectrum in the scientific world especially in the treatment of various diseases. Determining of the boundaries of the treatment methods of various diseases using stem cells have attracted our attention like many other researchers and also have led to planning such a thesis thopic.In living organisms, stem cells which have self-renewing and differentiation are the most primitive, unspecialized cells in embryonic, fetal or adult tissues. Stem cells with these properties keep their numbers constant and can differentiate in need into specific cells of the tissues where they located. Stem cells are classified according to their differentiation potential. The zygote and early blastomeres are totipotent stem cells that make up a full organism including extraembryonic lineages. A pluripotent stem cell can generate all cells of the three germ layers, but not the extraembryonic trophoblast. The more restricted multipotent stem cells only give rise to cells of a specific tissues.

Stem cells can be obtained from various sources. One of these sources is also umbilical cord blood. The very promising features of cord blood stem cell studies have been attracting more and more interest nowadays. Compared to the well-known stem cell sources such as bone marrow, peripheral blood and adipose tissue, cord blood consists of younger cells with a higher survival ability.

In the planned thesis study, it is aimed to determine stem cells isolated from umbilical cord blood, to grow these cells in vitro in different conditions, to determine adaptation of these different conditions and ensure continity of the culture media.
ÜNİŞ Çağdaş

Danışman : Prof.Dr. Melike ERKAN

Anabilim Dalı : Biyoloji

Programı : Zooloji

Mezuniyet Yılı : 2011

Tez Savunma Jürisi : Prof. Dr. Melike ERKAN

Prof. Dr. Gülşen TİMUR

Prof.Dr.Cihan DEMİRCİ TANSEL

<sup>Y. Doç. Dr. Meliha İNCELİ

Y. Doç. Dr. Ferhat ÇAĞILTAY</sup>