Is NAAT safe?
There were no studies on the safety of NAAT compared with current testing (AFB microscopy, tissue biopsy and/or culture). As NAAT is usually conducted on the same samples used for other testing, and there is no need for resampling, no AEs were expected.
To date, NAAT has been widely used without any safety concerns. However, more patients will receive a false-positive NAAT than a false-positive AFB result. Therefore, more patients will receive treatment for a disease they do not have and will possibly have an adverse reaction to the anti-TB drugs until clinical unresponsiveness is noted or culture results become available.
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