An assessment of nucleic acid amplification testing for active mycobacterial infection


Stage 3: Assessment of the body of evidence



Yüklə 3,88 Mb.
səhifə51/143
tarix04.01.2022
ölçüsü3,88 Mb.
#60347
1   ...   47   48   49   50   51   52   53   54   ...   143

Stage 3: Assessment of the body of evidence


Appraisal of the body of evidence was conducted along the lines suggested by the NHMRC in their guidance on clinical practice guideline development (NHMRC 2009). The five components considered essential by the NHMRC when judging the body of evidence are the:

evidence-base—which includes the number of studies sorted by their methodological quality and relevance to patients

consistency of the study results—whether the better quality studies had results of a similar magnitude and in the same direction i.e. homogenous or heterogeneous findings

potential clinical impact—appraisal of the precision, size and clinical importance or relevance of the primary outcomes used to determine the safety and effectiveness of the test

generalisability of the evidence to the target population

applicability of the evidence—integration of this evidence for conclusions about the net clinical benefit of the intervention in the context of Australian clinical practice.

A matrix for assessing the body of evidence for each research question, according to the components above, was used for this assessment (Table ).

Table Body of evidence matrix




Yüklə 3,88 Mb.

Dostları ilə paylaş:
1   ...   47   48   49   50   51   52   53   54   ...   143




Verilənlər bazası müəlliflik hüququ ilə müdafiə olunur ©muhaz.org 2024
rəhbərliyinə müraciət

gir | qeydiyyatdan keç
    Ana səhifə


yükləyin