Basingstoke and north hampshire hospital pathology user handbook

CHEMICAL PATHOLOGY

TEST	SPECIMEN CONTAINER	VOLUME NEEDED	SAMPLE TYPE	REFERENCE RANGES	UNITS	SPECIAL PRECAUTIONS	KEY FACTORS	REFERRAL LABORATORY (INC ADDRESS)	TURN – AROUND (working days)
Alpha 1 Antitrypsin (AAT)	Gold Top Vacuette	4mL	Serum	0M-6M 0.8 - 1.8 7M-5Y 1.1 - 2.2 6Y-10Y 1.4 - 2.3 11Y-15Y 1.2 - 2.0 >16Y 1.1 - 2.1	g/L				24 HOURS
Angiotensin converting enzyme (ACE)	Gold Top Vacuette	4mL	Serum	20 - 95	IU/L	Lab Note: SAS -20°C		Chemical Pathology Level D South Block Southampton General Hospital Tremona Road Southampton SO16 6YD 02380 796427	10 DAYS
Acetylcholine receptor Abs	Gold Top Vacuette	4mL	Serum	0 - 5	nmol/L	Lab Note: SAS -20°C MGAB		Immunology Churchill Hospital Headington Oxford OX3 7LJ 01865 225995	18 DAYS

TEST	SPECIMEN CONTAINER	VOLUME NEEDED	SAMPLE TYPE	REFERENCE RANGES	UNITS	SPECIAL PRECAUTIONS	KEY FACTORS	REFERRAL LABORATORY (INC ADDRESS)	TURN – AROUND (working days)
Adrenocorticotrophic Hormone (ACTH)	Lavender Top Vacuette	3mL	EDTA Plasma	0 - 40	ng/L	TO LAB AT ONCE - SAMPLE MUST BE FROZEN WITHIN 30 MINUTES Lab Note: SAS -20°C	Plasma ACTH concentrations may be affected by stress / acute illness and reduced in patients on corticosteroid therapy	Specialist Biochemistry Mail Point 8 Level C South Block Southampton General Hospital Tremona Road Southampton SO16 6YD 02380 798717	14 DAYS
Acylcarnitines	(see Carnitines)
Acetylcholinesterase	Lavender Top Vacuette	3mL	EDTA Whole Blood	>160	dau/L			Health and Safety Laboratory Harper Hill Buxton Derbyshire SK17 9JN 01298 218099	14 DAYS
Adrenal antibodies	Gold Top Vacuette	4mL	Serum	_	_	Lab Note: SAS -20°C ADAB		Sheffield Protein Department of Immunology Protein Reference Unit PO Box 894 Sheffield S5 7YT 01142 715552	14 DAYS

TEST	SPECIMEN CONTAINER	VOLUME NEEDED	SAMPLE TYPE	REFERENCE RANGES	UNITS	SPECIAL PRECAUTIONS	KEY FACTORS	REFERRAL LABORATORY (INC ADDRESS)	TURN – AROUND (working days)
Alphafoetoprotein (AFP)	Gold Top Vacuette	4mL	Serum	0 - 10	kU/L		Serum AFP levels are raised during pregnancy and in the neonatal patient		24 HOURS
Auto Immune Profile (AIP)	Gold Top Vacuette	4mL	Serum						10 DAYS
Albumin	Gold Top Vacuette	4mL	Serum	32 - 48	g/L				4 HOURS
Albumin - urine (micro albumin - Albumin Creatinine Ratio)	Plain (white top) Universal	10 mL	Urine	0 - 3.0	mg/L	Lab Note: Spin & Rack			24 HOURS
Alcohol - blood	Gold Top Vacuette	4mL	Serum	Legal driving limit < 800	mg/L	Discuss with Consultant Biochemist			12 HOURS
Alcohol - urine	Plain (white top)Universal	10mL	Urine		mg/L	Discuss with Consultant Biochemist			12 HOURS
Aldosterone	Lavender Top Vacuette	3mL	EDTA Plasma	Adult: Supine <160 Ambulant 40 – 310 Aldosterone/ Renin ratio 0 - 25	ng/L ng/mu	TO LAB AT ONCE - SAMPLE MUST BE FROZEN WITHIN 30 MINUTES Lab Note: SAS -20°C	Plasma Aldosterone concentrations may be affected by patients’ antihypertension or mineralosteroid drug therapy and may be reduced in patients with hypokalaemia	Specialist Biochemistry Mail Point 8 Level C South Block Southampton General Hospital Tremona Road Southampton SO16 6YD 02380 798717	14 DAYS

TEST	SPECIMEN CONTAINER	VOLUME NEEDED	SAMPLE TYPE	REFERENCE RANGES	UNITS	SPECIAL PRECAUTIONS	KEY FACTORS	REFERRAL LABORATORY (INC ADDRESS)	TURN – AROUND (working days)
Alkaline Phosphatase	Gold Top Vacuette	4mL	Serum	Children: 0 - 3yr 145-320 4 - 6yr 150-380 7 - 9yr 175-420 10 -11yr 135-530 12-13yr (M) 200-495 12-13 yr (F) 105-420 14-15yr (M) 130-525 14-15yr (F) 70-230 16-19yr (M) 65-260 16-19yr (F) 50-130 Adult: 20 - 59yr (M) 40 - 105 20 - 59yr(F) 35 - 110 60 - 79yr (M) 40 - 105 60 - 79yr (F) 40 - 115 80 - 89yr (M) 40 - 120 80 - 89yr (F) 40 - 125 >89yr (M) 40 - 140 >89yr (F) 40 - 130	IU/L		Alk Phos levels are physically increased in neonates, children, adolescents and pregnancy. In vitro haemolysis will falsely decrease results		4 HOURS

TEST	SPECIMEN CONTAINER	VOLUME NEEDED	SAMPLE TYPE	REFERENCE RANGES	UNITS	SPECIAL PRECAUTIONS	KEY FACTORS	REFERRAL LABORATORY (INC ADDRESS)	TURN – AROUND (working days)
Alkaline phosphatase - bone	see Alk Phos Isoenzyme
Alk Phos Isoenzymes	Gold Top Vacuette	4mL	Serum			Lab Note: Load tray AND SAS -20°C			10 DAYS
Alpha 1 antitrypsin phenotype	Gold Top Vacuette	4mL	Serum			Lab Note: SAS -20°C		Sheffield Protein Department of Immunology Protein Reference Unit PO Box 894 Sheffield S5 7YT 01142 715552	14 DAYS
ALT	Gold Top Vacuette	4mL	Serum	0 – 12yr 0 - 40 >12yrs 0 - 60	IU/L				4 HOURS
Aluminium	Gold Top Vacuette	4mL	Serum	< 0.4	umol/L	Lab Note: SAS -20°C		Trace Metals Unit Chemical Pathology Level D South Block Southampton General Hospital Tremona Road Southampton SO16 6YD 02380 796237	10 DAYS