Basingstoke and north hampshire hospital pathology user handbook

Connective Tissue Antibodies	Gold Top Vacuette	4mL	Serum
Lab Note: ANAE 4°C			10 DAYS
Complement	see C3 & C4
Copper - serum	Dark Blue Vacuette	6mL	Plasma	12 – 26	umol/L	Must be bled in Phlebotomy Lab NB: Teklab -20ºC Li Hep may be used for Paeds		Trace Metals Unit Chemical Pathology Level D South Block So’ton General Hosp Tremona Road Southampton SO16 6YD 02380 796237	14 DAYS
Copper - urine	Plain 24h bottle		Urine	< 0.9	umol/d	24 hour collection Lab Note: Univ 4ºC		Trace Metals Unit Chemical Pathology Level D South Block So’ton General Hosp Tremona Road Southampton SO16 6YD 02380 796237	14 DAYS
Cortisol - serum	Gold Top Vacuette	4mL	Serum	119 – 619	nmol/L		Levels may be affected by stress, diurnal rhythm and corticosteroid therapy		24 HOURS

TEST

SPECIMEN CONTAINER

VOLUME NEEDED

SAMPLE TYPE

REFERENCE RANGES

UNITS

SPECIAL PRECAUTIONS

KEY FACTORS

REFERRAL LABORATORY (INC ADDRESS)

TURN – AROUND (working days)

Cortisol - urine

Plain 24h bottle

Urine

55 - 250

nmol/d

Lab Note: Univ 4ºC

Levels may be affected by stress and corticosteroid therapy

Chemical Pathology West Park Hospital Epsom Surrey KT19 8PB 01372 734724

10 DAYS

Cotinine

Plain (white top) Universal

10mL

Urine

Lab Note: Univ -20ºC

Dept of Chemical Pathology Level D South Block Southampton General Hospital Tremona Road Southampton SO16 6YD 02380 796427

10 DAYS

CPK

See Creatine Kinase

Creatine kinase

Gold Top Vacuette

4mL

Serum

0 -1mth 0 - 244 2mth-15Y 0-220 Adult M 0 – 195 Adult F 0 – 170

IU/L

Strong interference from haemolysis

4 HOURS

Creatinine

Gold Top Vacuette

4mL

Serum

<2 days 40 - 100 2d - 30d 40 - 80 1m – 1y 30 - 60 2y - 12y 30 - 80 13y - 16y 40 - 120 17y – 18y 40 - 120 >18y(adult) 62 - 124

umol/L

Adult males with increased muscle mass may have slightly elevated serum concentrations without underlying renal pathology

4 HOURS

Creatinine

Plain 24h bottle

Urine

9 - 27

mmol/d

Lab Note: White top universal

24 HOURS

TEST

SPECIMEN CONTAINER

VOLUME NEEDED

SAMPLE TYPE

REFERENCE RANGES

UNITS

SPECIAL PRECAUTIONS

KEY FACTORS

REFERRAL LABORATORY (INC ADDRESS)

TURN – AROUND (working days)

Creatinine Clearance

Plain 24h bottle

Urine

90 - 120

mLs/min

Serum sample also needed

24 HOURS

Cross Links

See UDPD

CRP

Gold Top Vacuette

4mL

Serum

0 - 5

mg/L

4 HOURS

Cryoglobulins

Gold Top Vacuette & Lavender Top Vacuette

4mL & 3mL

Serum & EDTA Plasma

COLLECT WARMED TUBES IN WARMED FLASK FROM LAB. IMMEDIATELY TAKE SAMPLES. RETURN SAMPLES TO LAB IN FLASK IMMEDIATELY. Lab NB: Manual BMS

May be referred as follow up to in-house findings

Protein Reference Unit 2nd Floor, Jenner Wing St George's Hospital Medical School Cranmer Terrace LONDON SW17 0NH 02087250025

4 DAYS or 21days if referred

CSF Protein

Plain (white top) universal

1mL

CSF

0.1 - 0.4

g/L

4 HOURS

Cyclosporin A:

Lavender Top Vacuette

3mL

EDTA Whole blood

ug/L

Lab Note: WB 4ºC

Chemical Pathology Level D South Block Southampton General Hospital Tremona Road Southampton SO16 6YD 02380 796427

7 DAYS

Cystic fibrosis gene screen

Lavender Top Vacuette

3mL

EDTA Whole Blood

Results returned direct to requesting physician Lab Note: WB 4ºC

Wessex Regional Genetics Laboratoy Salisbury District Hospital Odstock Salisbury SP2 8BJ 01722 429080

6 WEEKS

C-reactive protein

see CRP

TEST	SPECIMEN CONTAINER	VOLUME NEEDED	SAMPLE TYPE	REFERENCE RANGES		UNITS	SPECIAL PRECAUTIONS	KEY FACTORS	REFERRAL LABORATORY (INC ADDRESS)	TURN – AROUND (working days)
Dehydro-cholesterol	Gold Top Vacuette	4mL	Serum				Lab Note: SAS -20°C		Newborn Screening & Biochemical Genetics Dept Southmead Hospital Westbury-on-Trym Bristol BS10 5NB 0117 3235556	5 WEEKS
Desmethyl-clobazam	Gold Top Vacuette	4mL	Serum	< 2000		ug/L	Lab Note: SAS -20°C		Medical Toxicology Lab 3^rd Floor, Block 7 South Wing St Thomas’ Hospital London SE1 7EH 02071 888689	10 DAYS
DHEAS:	Gold Top Vacuette	4mL	Serum	Male 0 – 30d	1.0 – 10.2	umol/L				14 DAYS
				1m – 5m	0.1 – 2.8
				6m – 5y	0.1 – 2.2
				6y – 9y	0.2 – 2.7
				10y – 39y	3.3 – 17.4
				40y – 59y	1.9 – 14.4
				>60y	0.8 – 7.9
				Female 0 – 30d	1.0 – 10.2
				1m – 5m	0.1 – 2.8
				6m – 5y	0.1 – 2.2
				6y – 9y	0.2 – 2.7
				10y – 39y	1.0 – 11.7
				40y – 59y	1.0 – 11.7
				>60y	0.8 – 7.0

TEST	SPECIMEN CONTAINER	VOLUME NEEDED	SAMPLE TYPE	REFERENCE RANGES	UNITS	SPECIAL PRECAUTIONS	KEY FACTORS	REFERRAL LABORATORY (INC ADDRESS)	TURN – AROUND (working days)
Diuretic screen	Plain (white top) Universal	10mL	Urine			Lab Note: Univ 4ºC		Regional Laboratory for Toxicology Dudley Road Winson Green Birmingham B18 7QH 0121 507 6029	14 DAYS
Digoxin	Gold Top Vacuette	4mL	Serum	0.6 - 2.0	ug/L	Take sample 6 Hours post dose			24 HOURS
DNA antibodies	Gold Top Vacuette	4mL	Serum	0 – 15	iu/mL	Lab Note: SAS 4°C DNA		Southampton Immunology Mailpoint 8 Level C Southampton General Hospital Tremona Road Southampton SO16 6YD 02380 796615	10 DAYS
DNA binding	Gold Top Vacuette	4mL	Serum			Lab Note: SAS 4°C DNA		Southampton Immunology Mailpoint 8 Level C Southampton General Hospital Tremona Road Southampton SO16 6YD 02380 796615	10 DAYS
DNA Genetics	Lavender Top Vacuette	3mL	EDTA Whole Blood			Results returned direct to requesting physician Lab Note: WB 4ºC		Wessex Regional Genetics Laboratory Salisbury District Hospital Odstock Salisbury SP2 8BJ 01722 429080	6 WEEKS Results returned direct to requesting physician
Dothiepin	Gold Top Vacuette	4mL	Serum		ug/L	Lab Note: SAS -20°C		Contact Consultatnt Biochemsit