Bio-data name & full Corresponding Address

BIO-DATA

1. Name & full Corresponding Address

Dr. Somendu Kumar Roy

Analytical Chemistry Division
CSIR-INDIAN INSTITUTE OF TOXICOLOGY RESEARCH
(Council of Scientific and Industrial Research)
VISHVIGYAN BHAVAN, 31, MAHATMA GANDHI MARG,
LUCKNOW-226001 (U.P.) INDIA



2. Email(s) and contact number(s)

E-mail: [e-mail]; [e-mail]

Contact Number: Tel: [phone] Extension: 231

Mob. No.-[phone]

3. Institution:

CSIR-INDIAN INSTITUTE OF TOXICOLOGY RESEARCH
(Council of Scientific and Industrial Research)
VISHVIGYAN BHAVAN, 31, MAHATMA GANDHI MARG,
LUCKNOW-226001 (U.P.) INDIA

4. Date of Birth: 15-08-1982

5. Research Area:



6. Academic Qualification (Undergraduate Onwards)

SI. No.	Degree/ Certificate	Year of Passing	University/Institute	Subject
1.	B.Pharm	2005	Jamia Hamdard, New Delhi	Pharmaceutical Science
2.	M.S.(Pharm)	2007	NIPER, Mohali	Natural Products Chemistry
3.	Ph. D.	2014	NIPER, Mohali	Natural Products Chemistry

7. Work experience (in chronological order)

SI. No.	From	To	Name of Institute	Position Held
1.	SEP 2007	JULY 2008	DEPARTMENT OF NATURAL PRODUCTS, Piramal Life Sciences Ltd., Mumbai	Research Associate
2.	SEP 2013	DEC 2013	NATURAL DRUG DIVISION, SAMI LABS, Bangalore	Scientist
3.	DEC 2013	Till date	Analytical Chemistry Section, CSIR-IITR, Lucknow	Scientist

8. Professional Recognition/ Award/ Prize/ Certificate, Fellowship received by the applicant

S.No.	Name of Award	Awarding Agency	Year
1	GATE-2005	IIT Bombay	2005
2	GATE-2006	IIT--Kharagpur	2006
3	JRF-Fellowship	NIPER	July2008-June-2010
4	SRF-Fellowship	NIPER	July 2008-June 2013
5	DST-Travel Grant	DST	2012
6	ICMR-Travel Grant	ICMR	2012
7	DS Kothari Post Doc Fellowship	UGC	2013
8	Young Scientist Award (Pharmacy / Chemistry)	Venus International Foundation-2015	Dec-2015
9	Early Career Research Award	SERB, New Delhi	Nov-2015

9. Publications (List of papers published in SCI Journals, in year wise descending order).
Kushwaha R, Mishra J, Tripathi S, Raza W, Mandrah K, Roy SK, Bandyopadhyay S. Arsenic attenuates Heparin-binding EGF-like growth factor/EGFR signalling that promotes matrix-metalloprotease-9-dependent astrocyte damage in the developing rat brain. Toxicol Sci. 2018, 1–23. doi: 10.1093/toxsci/kfx264.
Mandrah K, Satyanarayana G.N.V., Roy SK*. Development of a dispersive liquid-liquid microextraction method based on solidification of floating organic droplet followed by injector port silylation coupled with GC-MS/MS for simultaneous determination of nine bisphenols in bottled carbonated beverages. Journal of Chromatography A, 2017, 1528, 10-17.
Shayan Mohd, Jagriti Shukla, Aparna S. Kushwaha, Kapil Mandrah, Jai Shankar, Nidhi Arjaria, Prem N. Saxena, Ram Narayan, Somendu K. Roy and Manoj Kumar. Endophytic Fungi Piriformospora indica Mediated Protection of Host from Arsenic Toxicity. Front Microbiol. 2017; 8: 754.
Singh VK, Arora D, Satija NK, Khare P, Roy SK*, Sharma PK*. Intricatinol synergistically enhances the anticancerous activity of cisplatin in human A549 cells via p38 MAPK/p53 signalling. Apoptosis, 2017, Jul 29. doi: 10.1007/s10495-017-1404-0.

Dhiman, N, Fatima, F, Saxsena, PN, Roy, S, Rout, PK & Patnaik, S. Predictive modeling and validation of arsenite removal by a one pot synthesized bioceramic buttressed manganese doped iron oxide nanoplatform. RSC Advances, 2017, 7, 32866-32876.

Khan, H, Singh, RD, Tiwari, R, Gangopadhyay, S, Roy, SK, Singh, D & Srivastava, V. Mercury exposure induces cytoskeleton disruption and loss of renal function through epigenetic modulation of MMP9 expression. Toxicology, 2017, 386, 28-39.

Markandeya, Shukla, SP, Dhiman, N, Mohan, D, Kisku, GC & Roy, S An Efficient Removal of Disperse Dye from Wastewater Using Zeolite Synthesized from Cenospheres. Journal of Hazardous, Toxic, and Radioactive Waste, 2017, 21, 04017017.

Mohd, S, Shukla, J, Kushwaha, AS, Mandrah, K, Shankar, J, Arjaria, N, Saxena, PN, Narayan, R, Roy, SK & Kumar, M. Endophytic Fungi Piriformospora indica Mediated Protection of Host from Arsenic Toxicity. Frontiers in microbiology, 2017, doi: 10.3389/fmicb.2017.00754.

Pandey, R, Rai, V, Mishra, J, Mandrah, K, Roy, SK & Bandyopadhyay, S. Arsenic induces hippocampal neuronal apoptosis and cognitive impairments via an up-regulated BMP2/Smad-dependent reduced BDNF/TrkB signalling in rats. Toxicological Sciences, 2017, 159, 137–158. https://doi.org/10.1093/toxsci/kfx124

Tiwari, R., Singh, R. D., Khan, H., Gangopadhyay, S., Mittal, S., Singh, V., Arjaria, N., Shankar, J., Roy, S. K., Singh, D. & Srivastava, V. Oral Subchronic Exposure to Silver Nanoparticles Causes Renal Damage through Apoptotic Impairment and Necrotic Cell Death. Nanotoxicology, 2017, 11, 671-686.

Khan S, Bhatia T, Trivedi P, Satyanarayana G.N.V., Mandrah K, Saxena PN, Mudiam MKR, Roy SK*. Selective solid-phase extraction using molecularly imprinted polymer as a sorbent for the analysis of fenarimol in food samples. Food Chemistry, 2016, 199, 870–875.
Roy SK, Bairwa K, Grover J, Srivastava A, Jachak S. M. Determination of negundoside and agnuside in vitex negundo by qNMR and method validation. Journal of Analytical Chemistry, 2015, 70, 639-646.
Grover J, Roy SK, Jachak SM. Potassium carbonate mediated efficient and convenient synthesis of 3-methyl-1-phenylchromeno[4,3-c]pyrazol-4(1H)-ones. Synthetic Communications, 2014, 44, 1914-1923.
Roy SK, Pahwa S, Kumari N, Jachak SM and Nandanwar HS. NorA efflux pump inhibitory activity of coumarins from Mesua ferrea. Fitoterapia, 2013, 90, 140-150.
Bairwa K, Singh IN, Roy SK, Grover J, Shrivastava A, Jachak SM. Rotenoids from Boerhaavia diffusa as cyclooxygenase (COX)-1, COX-2 inhibitors. Journal of Natural Products, 2013, 76, 1393-8.
Roy SK, Bairwa K, Grover J, Srivastava A, Jachak SM. Analysis of flavonoids and iridoids in Vitex negundo Linn.by HPLC-PDA and method validation. Natutal Product Communications, 2013, 8, 241-244.
Roy SK, Kumari N, Gupta S, Pahwa S, Nandanwar H, Jachak SM.7-Hydroxy-(E)-3-phenylmethylene-chroman-4-oneanalogues as efflux pump inhibitors against Mycobacterium smegmatis mc² 155.European Journal of Medicinal Chemistry, 2013, 66, 499-507.
Chandna N, Kumar S, Kaushik P, Kaushik D,Roy SK, Gupta GK, Jachak SM,Kapoor JK, Sharma PK. Synthesis of novel celecoxib analogues by bioisosteric replacement of sulfonamide as potent inflammatory agents and cyclooxygenase inhibitors. Bioorganic Medicinal Chemistry, 2013, 21, 4581-4590.
Mishra PD, Deshmukh SK, Kulkarni-Almeida A, Roy SK, Jain S, Verekar A,Blakrishnan, Vishwakarma R. Anti-inflammatory & anti-diabetic naphthoquinones from an endophyticfungus. Indian Journal of Chemical Seciety B, 2013, 52, 565-567.
Roy SK, Srivastava A, Jachak SM. Analysis of homoisoflavonoids in Caesalpinia digyna by HPLC-ESI-MS, HPLC and method validation. Natural Product Communications, 2012,7,1189-1192.
Roy SK, Pahwa S, Nandanwar HS and Jachak SM. Phenylpropanoids of Alpinia galanga as efflux pump inhibitors in Mycobacterium smegmatismc²155. Fitoterapia, 2012, 83, 1248-1255.
Roy SK, Agrahari UC, Gautam R, Srivastava A, Jachak SM. Isointricatinol, a new antioxidant homoisoflavonoid from the roots of Caesalpinia digyna Rottler. Natural Product Research, 2012,26, 690-695.
Birari R, Roy SK, Singh A, Bhutani KK. Pancreatic lipase inhibitory alkaloids of Murraya koenigii leaves. Natural Product Communications, 2009, 4,1089-1092.
10. Books/Reports/Chapters/General articles etc
Chapters: Jachak S, Roy SK, Gupta S, Ahirrao P, Gibbons S. 2012. Small molecule efflux pump inhibitors from natural products as a potential source of antimicrobial agents. In: Tegos GP, ed. Antimicrobial Drug Discovery: Emerging Strategies. UK: CAB International, 62-76.
List of Conference/Symposium attended:
Roy SK, Gupta S, Kumari N, Pahwa S, Nandanwar HS and Jachak SM. Synthesis of homoisoflavonoids as efflux pump inhibitors. Presented in international conference on Gordon Research Conference‐Natural Products on 22nd‐27th July. 2012 at Proctor Academy, Andover, NH, USA.
Roy SK, Pahwa S, Nandanwar HS and Jachak SM. Coumarins of Mesua ferrea as modulator of ethidium bromide susceptibility against Mycobacterium smegmatis mc² 155. Presented in International conference on developments in drug discovery from natural products and traditional medicines (DDNP‐TM) on 22th‐24th Nov. 2012, at NIPER, Mohali, India.
Bairwa K, Roy SK, Singh IN, Jachak SM. Rotanoids of Boerhavia diffusa as cyclooxygenase (COX)‐1, COX‐2 inhibitors. Presented in International conference on developments in drug discovery from natural products and traditional medicines (DDNP‐TM) on 22th‐24th Nov. 2012, at NIPER, Mohali, India.
Swetha, Roy SK, Jachak SM. Synthesis of ursolic acid derivatives for α‐glucosidase inhibitory activity. Presented in International conference on developments in drug discovery from natural products and traditional medicines (DDNP‐TM) on 22th‐24th Nov. 2012, at NIPER, Mohali, India.
Pahwa S, Roy SK, Nandanwar HS and Jachak SM. Phenylpropanoids from Alpinia galanga as modulator of ethidium bromide susceptibility against Mycobacterium Smegmatis mc² 155. Presented in international conference on Open Source for Computer Aided Drug Discovery (OSCADD) on 22nd‐26th Feb. 2012 at IMTECH, Chandigarh, India.
Roy SK, Gupta S, Tegos GP, Jachak SM. Homoisoflavonoids as efflux pump inhibitors. Presented in International conference on developments in drug discovery from natural products and traditional medicines (DDNP‐TM) on 20th‐24th Nov. 2010, at NIPER, Mohali, India.