Bronchial Obstruction in Children

For all patients with BOS antitussives are excluded.

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• Appointment of combined preparations containing ephedrine 
(Solutan, Broncholytin) is possible only in rare cases of 
overproduction of abundant liquid bronchial secretion, as 
ephedrine has an expressed "drying" effect. 
• At expressed secretion, mucoregulatory products based on 
carbocisteine (Broncatar, Mucodyne, Mucopront) can be used. 

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• Thus, the program of expectorative and mucolytic 
therapy is made individually according to clinical 
course of the disease in each patient and should 
help to restore a patient’s adequate mucociliary 
clearance. 

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Antihistamines
• The use of antihistamines is indicated only at the occurrence or 
at worsening of any allergic reactions. 
• Second-generation drugs having no effect on the viscosity of 
sputum are favored. Beginning from 6 months of age 
Ceterizinum ("Zyrtec") is allowed by 0.25 mg / kg 1-2 times 
per day. 
• For children over 2 years old, Loratadinum ("Claritine"), 
Desloratadinum ("Aerius") can be prescribed, over 5 - 
Fexofenadinum ("Telfast").

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Bronchodilator therapy 
•
Short-acting 
β
2- agonists are used (Salbutamol, Fenoterolum) - drugs of choice. 
•
Preparations are highly selective and therefore have few side effects. 
•
Bronchodilator effect at inhalation use occurs within 5-10 minutes. 
•
A single dose of Salbutamol is 100-200mkg (1-2 doses), via a nebulizer a single 
dose may be considerably higher and is 2.5 mg (nebula by 2,5ml 0.1% solution). 
Administered by 3-4 times a day. 
•
In severe course of BOS torpid to treatment, as a "first aid treatment“, the 
introduction of three inhalations of short-acting 
β
2- agonists for one hour with an 
interval of 20 minutes is possible.

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