Course Organizers (2008-2009)
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| 11. AGING
2-4 February, 2009 Organizer: Rui Costa, IGC, Fundação Champalimaud Not yet provided 12. NEURODEGENERATIVE DISORDERS 9-14 February, 2009 Organizer: Tiago Fleming Outeiro, IMM Background The complex three-dimensional structure adopted by a protein in the cell is vital for its function. Oftentimes, as a consequence of environmental stress, genetic mutation, and/or infection, the folded structure of a protein gets altered causing multiple proteins to stick and fall out of solution in a process known as protein aggregation. These aggregates are, in many instances, pathological hallmarks in many diseases known as protein aggregation diseases. In protein aggregation diseases of the brain, incorrectly folded proteins self-associate, form fiber-like aggregates and are associated with neuronal cell death. In this course, the molecular and biochemical basis of protein folding and misfolding, and its connection to neurodegenerative disorders such as the prion diseases, Alzheimer's disease, Parkinson’s disease and Huntington's disease, will be covered. The proteins involved in all of these disorders, how the proteins' three dimensional structures change during the course of these afflictions, and the cellular quality control systems used to cope with protein misfolding will also be covered Finally, the course will address novel detection methods and therapies that are under development to treat neurodegenerative disorders. Faculty
13. REGENERATIVE MEDICINE: FROM BIOLOGY TO THE CLINIC 16-21 February 2009 Organizer: Domingos Henrique,FML/IMM, Miguel Ramalho Santos Univ California San Francisco AIMS:
To present and discuss the most recent developments in the area of stem cell biology, from the generation of embryonic stem cells to the isolation and characterization of various adult stem cells. In addition, various approaches to stem cell-based therapies will be discussed, with a critical evaluation of the field and future perspectives. Faculty Domingos Henrique, FML/IMM Miguel Ramalho-Santos, UCSF Jorge Pacheco, FCUL Manuel Abecassis, IPO Freddy Radtke, EPFL, Lausanne, Switzerland Phil Jones, Cambridge, UK J.T. Daniels, UCL, UK Giulio Cossu, Milan, Italy Christine Mummery – Utrecht, Netherlands Arturo Alvarez-Buylla, UCSF, USA This Course will include Seminars by the invited speakers, followed by general discussion of the topics. Students will have the opportunity to discuss selected papers in Journal Club sessions. Yüklə 378,97 Kb. Dostları ilə paylaş:
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