Field effectiveness of microbial larvicides on mosquito larvae in malaria areas of Botswana and Zimbabwe
The successful control of malaria vectors requires the control of both the larval and adult stages. The adult control methods through indoor residual spraying (IRS) and use of long-lasting insecticidal nets (L...
Mulamuli Mpofu, Piet Becker, Kaka Mudambo and Christiaan de Jager
Malaria Journal 2016 15:586
Global priorities for research and the relative importance of different research outcomes: an international Delphi survey of malaria research experts
As global research investment increases, attention inevitably turns to assessing and measuring the outcomes and impact from research programmes. Research can have many different outcomes such as producing adva...
Jo-Ann Mulligan and Lesong Conteh
Malaria Journal 2016 15:585
The return of chloroquine-susceptible Plasmodium falciparum malaria in Zambia
Plasmodium falciparum resistance to anti-malarial drugs remains a major obstacle to malaria control and elimination. The parasite has developed resistance to every anti-malarial drug i...
Sydney Mwanza, Sudhaunshu Joshi, Michael Nambozi, Justin Chileshe, Phidelis Malunga, Jean-Bertin Bukasa Kabuya, Sebastian Hachizovu, Christine Manyando, Modest Mulenga and Miriam Laufer
Malaria Journal 2016 15:584
Emerging polymorphisms in falciparum Kelch 13 gene in Northeastern region of India
Recent reports of emergence and spread of artemisinin resistance in the Southeast Asia region, including Myanmar, pose a greater threat to malaria control and elimination in India. Whole genome sequencing stud...
Neelima Mishra, Ram Suresh Bharti, Prashant Mallick, Om Prakash Singh, Bina Srivastava, Roma Rana, Sobhan Phookan, Hardev Prasad Gupta, Pascal Ringwald and Neena Valecha
Malaria Journal 2016 15:583
Perceptions on the effect of small electric fans on comfort inside bed nets in southern Ghana: a qualitative study
Long-lasting insecticidal nets (LLINs) are known to be highly effective in reducing malaria transmission, morbidity and mortality. However, among those owning an LLIN, use rates are often suboptimal. A reporte...
Mulako S. Jaeger, Olivier J. T. Briët, Joseph Keating, Collins K. Ahorlu, Joshua O. Yukich, Samuel Oppong, Peter Nardini and Constanze Pfeiffer
Malaria Journal 2016 15:580
Evaluation of long-lasting microbial larvicide for malaria vector control in Kenya
Outdoor malaria transmission is becoming an increasingly important problem in malaria control in Africa. Larval control is a promising intervention as it can target both indoor and outdoor biting mosquitoes. H...
Yaw A. Afrane, Nixon G. Mweresa, Christine L. Wanjala, Thomas M. Gilbreath III, Guofa Zhou, Ming-Chieh Lee, Andrew K. Githeko and Guiyun Yan
Malaria Journal 2016 15:577
Susceptibility of Anopheles gambiae to insecticides used for malaria vector control in Rwanda
The widespread emergence of resistance to pyrethroids is a major threat to the gains made in malaria control. To monitor the presence and possible emergence of resistance against a variety of insecticides used...
Emmanuel Hakizimana, Corine Karema, Dunia Munyakanage, Gad Iranzi, John Githure, Jon Eric Tongren, Willem Takken, Agnes Binagwaho and Constantianus J. M. Koenraadt
Malaria Journal 2016 15:582
In vitro and in vivo anti-malarial activity of novel harmine-analog heat shock protein 90 inhibitors: a possible partner for artemisinin
The emergence of artemisinin-resistant Plasmodium falciparum strains poses a serious challenge to the control of malaria. This necessitates the development of new anti-malarial drugs. Previous studies have shown ...
Abebe Genetu Bayih, Asongna Folefoc, Abu Naser Mohon, Scott Eagon, Marc Anderson and Dylan R. Pillai
Malaria Journal 2016 15:579
Environmental determinants of malaria transmission in African villages
Malaria transmission is complex, involving a range of hydroclimatological, biological, and environmental processes. The high degree of non-linearity in these processes makes it difficult to predict and interve...
Noriko Endo and Elfatih A. B. Eltahir
Malaria Journal 2016 15:578
Systematic review of the role of angiopoietin-1 and angiopoietin-2 in Plasmodium species infections: biomarkers or therapeutic targets?
Levels of both angiopoietin-1 (Ang-1) and angiopoietin-2 (Ang-2) correlate with malaria disease severity and are proposed as biomarkers and possible therapeutic targets. To establish their role in malaria, a s...
Gerdie M. de Jong, Jasper J. Slager, Annelies Verbon, Jaap J. van Hellemond and Perry J. J. van Genderen
Malaria Journal 2016 15:581
Characterizing the impact of sustained sulfadoxine/pyrimethamine use upon the Plasmodium falciparum population in Malawi
Malawi experienced prolonged use of sulfadoxine/pyrimethamine (SP) as the front-line anti-malarial drug, with early replacement of chloroquine and delayed introduction of artemisinin-based combination therapy....
Matt Ravenhall, Ernest Diez Benavente, Mwapatsa Mipando, Anja T. R. Jensen, Colin J. Sutherland, Cally Roper, Nuno Sepúlveda, Dominic P. Kwiatkowski, Jacqui Montgomery, Kamija S. Phiri, Anja Terlouw, Alister Craig, Susana Campino, Harold Ocholla and Taane G. Clark
Malaria Journal 2016 15:575
Plasmodium malariae in the Colombian Amazon region: you don’t diagnose what you don’t suspect
Malaria is a worldwide public health problem; parasites from the genus Plasmodium spp. are the aetiological agent of this disease. The parasite is mainly diagnosed by microscope-based techniques. However, these h...
Carlos Hernando Niño, Juan Ricardo Cubides, Paola Andrea Camargo-Ayala, Carlos Arturo Rodríguez-Celis, Teódulo Quiñones, Moisés Tomás Cortés-Castillo, Lizeth Sánchez-Suárez, Ricardo Sánchez, Manuel Elkin Patarroyo and Manuel Alfonso Patarroyo
Malaria Journal 2016 15:576
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