Cập nhật nghiên cứu về chẩn đoán-điều trị sốt rét đăng tải trên tạp chí quốc tế nổi tiếng năm 2016-2017

A monoclonal antibody-based immunoassay to measure the antibody response against the repeat region of the circumsporozoite protein of Plasmodium falciparum

The malaria vaccine candidate RTS,S/AS01 (GSK Vaccines) induces high IgG concentration against the circumsporozoite protein (CSP) of Plasmodium falciparum. In human vaccine recipients circulating anti-CSP antibod...

Kristina Radin, Frederic Clement, Erik Jongert, Yann G. J. Sterckx, Christian Ockenhouse, Jason Regules, Franck Lemiale and Geert Leroux-Roels

Malaria Journal 2016 15:543

Identification and characterization of microRNAs expressed in the African malaria vector Anopheles funestus life stages using high throughput sequencing

Over the past several years, thousands of microRNAs (miRNAs) have been identified in the genomes of various insects through cloning and sequencing or even by computational prediction. However, the number of mi...

Mushal Allam, Belinda L. Spillings, Hiba Abdalla, Darlington Mapiye, Lizette L. Koekemoer and Alan Christoffels

Malaria Journal 2016 15:542

Comparison of molecular quantification of Plasmodium falciparum gametocytes by Pfs25 qRT-PCR and QT-NASBA in relation to mosquito infectivity

Quantifying gametocyte densities in natural malaria infections is important to estimate malaria transmission potential. Two molecular methods (Pfs25 mRNA quantitative reverse transcriptase PCR (qRT-PCR) and Pfs25

Helmi Pett, Bronner P. Gonçalves, Alassane Dicko, Issa Nébié, Alfred B. Tiono, Kjerstin Lanke, John Bradley, Ingrid Chen, Halimatou Diawara, Almahamoudou Mahamar, Harouna M. Soumare, Sekou F. Traore, Ibrahima Baber, Sodiomon B. Sirima, Robert Sauerwein, Joelle Brown…

Malaria Journal 2016 15:539

Treatment-seeking behaviour and associated costs for malaria in Papua, Indonesia

Malaria remains a significant public health issue in Eastern Indonesia, where multidrug resistant Plasmodium falciparum and Plasmodium vivax are highly prevalent. The objective of this study was to describe treat...

Muhammad Karyana, Angela Devine, Enny Kenangalem, Lenny Burdarm, Jeanne Rini Poespoprodjo, Ram Vemuri, Nicholas M. Anstey, Emiliana Tjitra, Ric N. Price and Shunmay Yeung

Malaria Journal 2016 15:536

A new tool for the chemical genetic investigation of the Plasmodium falciparum Pfnek-2 NIMA-related kinase

Examining essential biochemical pathways in Plasmodium falciparum presents serious challenges, as standard molecular techniques such as siRNA cannot be employed in this organism, and generating gene knock-outs of...

Deborah F. Mitcheson, Andrew R. Bottrill, Katherine Carr, Christopher R. Coxon, Celine Cano, Bernard T. Golding, Roger J. Griffin, Andrew M. Fry, Christian Doerig, Richard Bayliss and Andrew B. Tobin

Malaria Journal 2016 15:535

Genetic diversity of the Pvk12 gene in Plasmodium vivax from the China-Myanmar border area

Plasmodium falciparum resistance to artemisinin emerged in the Greater Mekong Sub-region has been associated with mutations in the propeller domain of the kelch gene Pfk13.

Shuang Deng, Yonghua Ruan, Yao Bai, Yue Hu, Zeshuai Deng, Yongshu He, Rui Ruan, Yanrui Wu, Zhaoqing Yang and Liwang Cui

Malaria Journal 2016 15:528

Plasmodium infection and oxidative status in breeding great tits, Parus major

Plasmodium parasites may affect the oxidative status of their hosts, defined as the balance of pro-oxidant compounds and antioxidant defences in an organism. An increased energy requir...

Jessica Delhaye, Tania Jenkins and Philippe Christe

Malaria Journal 2016 15:531

Scaling-up the use of sulfadoxine-pyrimethamine for the preventive treatment of malaria in pregnancy: results and lessons on scalability, costs and programme impact from three local government areas in Sokoto State, Nigeria

Intermittent preventive treatment of malaria in pregnancy with 3+ doses of sulfadoxine-pyrimethamine (IPTp-SP) reduces maternal mortality and stillbirths in malaria endemic areas. Between December 2014 and Dec...

Nosa Orobaton, Anne M. Austin, Dele Abegunde, Mohammed Ibrahim, Zainab Mohammed, Jumare Abdul-Azeez, Hakeem Ganiyu, Zwalle Nanbol, Bolaji Fapohunda and Katherine Beal

Malaria Journal 2016 15:533

Antibody responses to the full-length VAR2CSA and its DBL domains in Cameroonian children and teenagers

Antigenic variation of Plasmodium falciparum erythrocyte membrane protein 1 is a key parasite mechanism for immune evasion and parasite survival. It is assumed that the number of parasites expressing the same var

Barriere A. Y. Fodjo, Njika Atemnkeng, Livo Esemu, Emile K. Yuosembom, Isabella A. Quakyi, Viviane H. M. Tchinda, Joseph Smith, Ali Salanti, Jude Bigoga, Diane W. Taylor, Rose G. F. Leke and Anna Babakhanyan

Malaria Journal 2016 15:532

Assessing demand-side barriers to uptake of intermittent preventive treatment for malaria in pregnancy: a qualitative study in two regions of Uganda

To prevent malaria infection during pregnancy in endemic areas in Africa, the World Health Organization recommends the administration of intermittent preventive treatment in pregnancy (IPTp) as part of the foc...

Christian Rassi, Kirstie Graham, Rebecca King, James Ssekitooleko, Patrobas Mufubenga and Sam Siduda Gudoi

Malaria Journal 2016 15:530

Serological markers to measure recent changes in malaria at population level in Cambodia

Serological markers for exposure to different Plasmodium species have recently been used in multiplex immunoassays based on the Luminex technology. However, interpretation of the assay results requires conside...

Karen Kerkhof, Vincent Sluydts, Laura Willen, Saorin Kim, Lydie Canier, Somony Heng, Takafumi Tsuboi, Tho Sochantha, Siv Sovannaroth, Didier Ménard, Marc Coosemans and Lies Durnez

Malaria Journal 2016 15:529