Cập nhật nghiên cứu về chẩn đoán-điều trị sốt rét đăng tải trên tạp chí quốc tế nổi tiếng năm 2016-2017

Infections with Plasmodium falciparum during pregnancy affect VAR2CSA DBL-5 domain-specific T cell cytokine responses

Current knowledge of human immunological responses to pregnancy-associated malaria-specific Plasmodium falciparum protein VAR2CSA concerns almost exclusively B cell-driven antibody-mediated activity. Knowledge o...

Komi Gbédandé, Gilles Cottrell, Bertin Vianou, Samad Ibitokou, Aurax Fernando, Marita Troye-Blomberg, Ali Salanti, Kabirou Moutairou, Achille Massougbodji, Nicaise Tuikue Ndam, Philippe Deloron, Adrian J. F. Luty and Nadine Fievet

Malaria Journal 2016 15:485

Stage-dependent fate of Plasmodium falciparum-infected red blood cells in the spleen and sickle-cell trait-related protection against malaria

Sickle-cell trait (HbAS) reduces falciparum malaria risk and suppresses parasitaemia. Although several candidate mechanisms have been proposed, their epidemiological, clinical and experimental correlates have ...

Seidina A. S. Diakité, Papa Alioune Ndour, Valentine Brousse, Frederick Gay, Camille Roussel, Sylvestre Biligui, Michaël Dussiot, Virginie Prendki, Tatiana M. Lopera-Mesa, Karim Traoré, Drissa Konaté, Saibou Doumbia, Jérôme Cros, Safi Dokmak, Rick M. Fairhurst, Mahamadou Diakité…

Malaria Journal 2016 15:482

Failure of dihydroartemisinin plus piperaquine treatment of falciparum malaria by under-dosing in an overweight patient

Artemisinin-based combination therapy (ACT) introduced in the mid-1990s has been recommended since 2005 by the World Health Organization as first-line treatment against Plasmodium falciparum in all endemic countr...

Jean Baptiste Roseau, Bruno Pradines, Nicolas Paleiron, Serge Vedy, Marylin Madamet, Fabrice Simon and Emilie Javelle

Malaria Journal 2016 15:479

Natural products from Zanthoxylum heitzii with potent activity against the malaria parasite

Zanthoxylum heitzii (Rutaceae) (olon) is used in traditional medicine in Central and West Africa to treat malaria. To identify novel compounds with anti-parasitic activity and validate...

Christopher Dean Goodman, Ingvild Austarheim, Vanessa Mollard, Bertin Mikolo, Karl Egil Malterud, Geoffrey I. McFadden and Helle Wangensteen

Malaria Journal 2016 15:481

Impact of the Mass Drug Administration for malaria in response to the Ebola outbreak in Sierra Leone

As emergency response to the Ebola epidemic, the Government of Sierra Leone and its partners implemented a large-scale Mass Drug Administration (MDA) with artesunate–amodiaquine (ASAQ) covering >2.7 million pe...

Maru Aregawi, Samuel J. Smith, Musa Sillah-Kanu, John Seppeh, Anitta R. Y. Kamara, Ryan O. Williams, John J. Aponte, Andrea Bosman and Pedro Alonso

Malaria Journal 2016 15:480

Cedrol, a malaria mosquito oviposition attractant is produced by fungi isolated from rhizomes of the grass Cyperus rotundus

Cedrol, a sesquiterpene alcohol, is the first identified oviposition attractant for African malaria vectors. Finding the natural source of this compound might help to elucidate why Anopheles gambiae and Anopheles...

Lynda K. Eneh, Hiromi Saijo, Anna-Karin Borg-Karlson, Jenny M. Lindh and Gunaratna Kuttuva Rajarao

Malaria Journal 2016 15:478

The association between household bed net ownership and all-cause child mortality in Madagascar

Malaria continues to be an important cause of morbidity and mortality in Madagascar. It has been estimated that the malaria burden costs Madagascar over $52 million annually in terms of treatment costs, lost p...

Dominique Meekers and Joshua O. Yukich

Malaria Journal 2016 15:475

Safety, efficacy and pharmacokinetic evaluations of a new coated chloroquine tablet in a single-arm open-label non-comparative trial in Brazil: a step towards a user-friendly malaria vivax treatment

Malaria remains a major public health problem, with half the world population at risk of contracting malaria. The effects of Plasmodium vivax on prosperity and longevity have been highlighted in several recent cl...

Dhelio Pereira, André Daher, Graziela Zanini, Ivan Maia, Lais Fonseca, Luciana Pitta, Rosilene Ruffato, Paola Marchesini and Cor Jesus Fontes

Malaria Journal 2016 15:477

Clinical development of placental malaria vaccines and immunoassays harmonization: a workshop report

Placental malaria caused by Plasmodium falciparum infection constitutes a major health problem manifesting as severe disease and anaemia in the mother, impaired fetal development, low birth weight or spontaneous ...

Arnaud Chêne, Sophie Houard, Morten A. Nielsen, Sophia Hundt, Flavia D’Alessio, Sodiomon B. Sirima, Adrian J. F. Luty, Patrick Duffy, Odile Leroy, Benoit Gamain and Nicola K. Viebig

Malaria Journal 2016 15:476

Probucol dramatically enhances dihydroartemisinin effect in murine malaria

Artemisinin-based combination therapy (ACT) has been adopted as national policy for the first-line treatment in large number of malaria-endemic regions. However, artemisinin-resistant parasites have emerged an...

Aiko Kume, Dang Trinh Minh Anh, Mototada Shichiri, Noriko Ishida and Hiroshi Suzuki

Malaria Journal 2016 15:472

Characterizing microscopic and submicroscopic malaria parasitaemia at three sites with varied transmission intensity in Uganda

Parasite prevalence is a key metric used to quantify the burden of malaria and assess the impact of control strategies. Most published estimates of parasite prevalence are based on microscopy and likely undere...

John Rek, Shereen Katrak, Hannah Obasi, Patience Nayebare, Agaba Katureebe, Elijah Kakande, Emmanuel Arinaitwe, Joaniter I. Nankabirwa, Prasanna Jagannathan, Chris Drakeley, Sarah G. Staedke, David L. Smith, Teun Bousema, Moses Kamya, Philip J. Rosenthal, Grant Dorsey…

Malaria Journal 2016 15:470