Cập nhật nghiên cứu về chẩn đoán-điều trị sốt rét đăng tải trên tạp chí quốc tế nổi tiếng năm 2016-2017

The use of formative research to inform the design of a seasonal malaria chemoprevention intervention in northern Nigeria

Experience of seasonal malaria chemoprevention (SMC) is growing in the Sahel sub-region of Africa, though there remains insufficient evidence to recommend a standard deployment strategy. In 2012, a project was...

Clare E. Strachan, Musa Kana, Sandrine Martin, John Dada, Naome Wandera, Madeleine Marasciulo, Helen Counihan, Maxwell Kolawole, Tanimu Babale, Prudence Hamade, Sylvia R. Meek and Ebenezer Baba

Malaria Journal 2016 15:474

Impact of interventions on malaria in internally displaced persons along the China–Myanmar border: 2011–2014

Internally displaced persons (IDP) represent vulnerable populations whose public health conditions merit special attention. In the China–Myanmar border area, human movement and resettlements of IDP can influen...

Guofa Zhou, Eugenia Lo, Daibin Zhong, Xiaoming Wang, Ying Wang, Sameer Malla, Ming-chieh Lee, Zhaoqing Yang, Liwang Cui and Guiyun Yan

Malaria Journal 2016 15:471

Approaches to estimating inbreeding coefficients in clinical isolates of Plasmodium falciparum from genomic sequence data

The advent of whole-genome sequencing has generated increased interest in modelling the structure of strain mixture within clinical infections of Plasmodium falciparum The life cycle of the parasite implies that...

John D. O’Brien, Lucas Amenga-Etego and Ruiqi Li

Malaria Journal 2016 15:473

Pathway-specific inhibition of primaquine metabolism by chloroquine/quinine

There has been some evidence to suggest that the addition of chloroquine (CQ) or quinine (QN) to 8-aminoquinoline (8-AQ) treatment regimens may increase the therapeutic efficacy of the 8-AQ and simultaneously ...

Pius S. Fasinu, Babu L. Tekwani, Bharathi Avula, Narayan D. Chaurasiya, N. P. Dhammika Nanayakkara, Yan-Hong Wang, Ikhlas A. Khan and Larry A. Walker

Malaria Journal 2016 15:466

An improved mosquito electrocuting trap that safely reproduces epidemiologically relevant metrics of mosquito human-feeding behaviours as determined by human landing catch

Reliable quantification of mosquito host-seeking behaviours is required to determine the efficacy of vector control methods. For malaria, the gold standard approach remains the risky human landing catch (HLC)....

Nicodem J. Govella, Deodatus F. Maliti, Amos T. Mlwale, John P. Masallu, Nosrat Mirzai, Paul C. D. Johnson, Heather M. Ferguson and Gerry F. Killeen

Malaria Journal 2016 15:465

A Phase II pilot trial to evaluate safety and efficacy of ferroquine against early Plasmodium falciparum in an induced blood-stage malaria infection study

Ferroquine (SSR97193) is a candidate anti-malarial currently undergoing clinical trials for malaria. To better understand its pharmacokinetic (PK) and pharmacodynamic (PD) parameters the compound was tested in...

James S. McCarthy, Thomas Rückle, Elhadj Djeriou, Cathy Cantalloube, Daniel Ter-Minassian, Mark Baker, Peter O’Rourke, Paul Griffin, Louise Marquart, Rob Hooft van Huijsduijnen and Jörg J. Möhrle

Malaria Journal 2016 15:469

Malaria risk factor assessment using active and passive surveillance data from Aceh Besar, Indonesia, a low endemic, malaria elimination setting with Plasmodium knowlesi, Plasmodium vivax, and Plasmodium falciparum

As malaria transmission declines, it becomes more geographically focused and more likely due to asymptomatic and non-falciparum infections. To inform malaria elimination planning in the context of this changin...

Herdiana Herdiana, Chris Cotter, Farah N. Coutrier, Iska Zarlinda, Brittany W. Zelman, Yusrifar Kharisma Tirta, Bryan Greenhouse, Roly D. Gosling, Peter Baker, Maxine Whittaker and Michelle S. Hsiang

Malaria Journal 2016 15:468

Assets and challenges facing caregivers when managing malaria in young children in rural Uganda

Despite efforts to improve malaria management for children, a substantial gap remains between policy and practice in Uganda. The aim of this study was to create quantitative profiles of assets and challenges f...

Rosemin Kassam, John Collins and Richard Sekiwunga

Malaria Journal 2016 15:467

Neutrophil gelatinase-associated lipocalin (NGAL) predicts the occurrence of malaria-induced acute kidney injury

Acute kidney injury (AKI) is a frequently encountered complication of imported Plasmodium falciparum infection. Markers of structural kidney damage have been found to detect AKI earlier than serum creatinine-base...

Marlies E. van Wolfswinkel, Liese C. Koopmans, Dennis A. Hesselink, Ewout J. Hoorn, Rob Koelewijn, Jaap J. van Hellemond and Perry J. J. van Genderen

Malaria Journal 2016 15:464

Intravascular haemolysis with haemoglobinuria in a splenectomized patient with severe Plasmodium knowlesi malaria

Haemoglobinuria is an uncommon complication of severe malaria, reflecting acute intravascular haemolysis and potentially leading to acute kidney injury. It can occur early in the course of infection as a conse...

Bridget E. Barber, Matthew J. Grigg, Timothy William, Tsin W. Yeo and Nicholas M. Anstey

Malaria Journal 2016 15:462

An inter-laboratory comparison of standard membrane-feeding assays for evaluation of malaria transmission-blocking vaccines

An effective malaria transmission-blocking vaccine may play an important role in malaria elimination efforts, and a robust biological assay is essential for its development. The standard membrane-feeding assay...

Kazutoyo Miura, Will J. R. Stone, Karin M. Koolen, Bingbing Deng, Luwen Zhou, Geert-Jan van Gemert, Emily Locke, Merribeth Morin, Teun Bousema, Robert W. Sauerwein, Carole A. Long and Koen J. Dechering

Malaria Journal 2016 15:463