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Glucagon-like peptide-1 analogue, liraglutide, in experimental cerebral malaria: implications for the role of oxidative stress in cerebral malaria



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Glucagon-like peptide-1 analogue, liraglutide, in experimental cerebral malaria: implications for the role of oxidative stress in cerebral malaria


Cerebral malaria from Plasmodium falciparum infection is major cause of death in the tropics. The pathogenesis of the disease is complex and the contribution of reactive oxygen and nitrogen species (ROS/RNS) in t...

Brian DellaValle, Casper Hempel, Trine Staalsoe, Flemming Fryd Johansen and Jørgen Anders Lindholm Kurtzhals

Malaria Journal 2016 15:427

Influence of the agrochemicals used for rice and vegetable cultivation on insecticide resistance in malaria vectors in southern Côte d’Ivoire


Vector control can contribute to the development of resistance to insecticides in malaria vectors. As the swamps and wetlands used for some agricultural activities constitute productive breeding sites for many...

Mouhamadou S. Chouaïbou, Behi K. Fodjo, Gilbert Fokou, Ouattara F. Allassane, Benjamin G. Koudou, Jean-Philippe David, Christophe Antonio-Nkondjio, Hilary Ranson and Bassirou Bonfoh

Malaria Journal 2016 15:426

Behavioural and neurological symptoms accompanied by cellular neuroinflammation in IL-10-deficient mice infected with Plasmodium chabaudi


Cerebral malaria is one of the most severe complications of Plasmodium falciparum infection and occurs mostly in young African children. This syndrome results from a combination of high levels of parasitaemia and...

Kyle D. Wilson, Sonja J. Stutz, Lorenzo F. Ochoa, Gustavo A. Valbuena, Petra D. Cravens, Kelly T. Dineley, Gracie Vargas and Robin Stephens

Malaria Journal 2016 15:428

Functional genomic analyses of Enterobacter, Anopheles and Plasmodium reciprocal interactions that impact vector competence


Malaria exerts a tremendous socioeconomic impact worldwide despite current control efforts, and novel disease transmission-blocking strategies are urgently needed. The Enterobacter bacterium Esp_Z, which is natur...

Nathan J. Dennison, Raúl G. Saraiva, Chris M. Cirimotich, Godfree Mlambo, Emmanuel F. Mongodin and George Dimopoulos

Malaria Journal 2016 15:425

Investigation of mechanisms of bendiocarb resistance in Anopheles gambiae populations from the city of Yaoundé, Cameroon


Resistance to the carbamate insecticide bendiocarb is emerging in Anopheles gambiae populations from the city of Yaoundé in Cameroon. However, the molecular basis of this resistance remains uncharacterized. The p...

Christophe Antonio-Nkondjio, Rodolphe Poupardin, Billy Fossog Tene, Edmond Kopya, Carlo Costantini, Parfait Awono-Ambene and Charles S. Wondji

Malaria Journal 2016 15:424

The impact of behaviour change communication on the use of insecticide treated nets: a secondary analysis of ten post-campaign surveys from Nigeria


Mass distribution campaigns of insecticide-treated nets for malaria prevention are usually accompanied by intensive behaviour change communication (BCC) to encourage hanging and use of nets. However, data on t...

Albert Kilian, Harriet Lawford, Chinazo N. Ujuju, Tarekegn A. Abeku, Ernest Nwokolo, Festus Okoh and Ebenezer Baba

Malaria Journal 2016 15:422

Assessment of submicroscopic infections and gametocyte carriage of Plasmodium falciparum during peak malaria transmission season in a community-based cross-sectional survey in western Kenya, 2012


Although malaria control intervention has greatly decreased malaria morbidity and mortality in many African countries, further decline in parasite prevalence has stagnated in western Kenya. In order to assess ...

Zhiyong Zhou, Rebecca M. Mitchell, Simon Kariuki, Christopher Odero, Peter Otieno, Kephas Otieno, Philip Onyona, Vincent Were, Ryan E. Wiegand, John E. Gimnig, Edward D. Walker, Meghna Desai and Ya Ping Shi

Malaria Journal 2016 15:421

A comparative molecular survey of malaria prevalence among Eastern chimpanzee populations in Issa Valley (Tanzania) and Kalinzu (Uganda)


Habitat types can affect vector and pathogen distribution and transmission dynamics. The prevalence and genetic diversity of Plasmodium spp. in two eastern chimpanzee populations—Kalinzu Forest Reserve, Uganda an...

Mwanahamisi I. Mapua, Klára J. Petrželková, Jade Burgunder, Eva Dadáková, Kristýna Brožová, Kristýna Hrazdilová, Fiona A. Stewart, Alex K. Piel, Peter Vallo, Hans-Peter Fuehrer, Chie Hashimoto, David Modrý and Moneeb A. Qablan

Malaria Journal 2016 15:423

Using supply side evidence to inform oral artemisinin monotherapy replacement in Myanmar: a case study


In 2012, alarmingly high rates of oral artemisinin monotherapy availability and use were detected along Eastern Myanmar, threatening efforts to halt the spread of artemisinin resistance in the Greater Mekong S...

Hnin Su Su Khin, Tin Aung, Moe Aung, Aung Thi, Matt Boxshall and Chris White

Malaria Journal 2016 15:418

Malaria intervention scale-up in Africa: effectiveness predictions for health programme planning tools, based on dynamic transmission modelling


Scale-up of malaria prevention and treatment needs to continue to further important gains made in the past decade, but national strategies and budget allocations are not always evidence-based. Statistical mode...

Eline Korenromp, Guy Mahiané, Matthew Hamilton, Carel Pretorius, Richard Cibulskis, Jeremy Lauer, Thomas A. Smith and Olivier J. T. Briët

Malaria Journal 2016 15:417

Malaria in urban, semi-urban and rural areas of southern of Gabon: comparison of the Pfmdr 1 and Pfcrt genotypes from symptomatic children


Artesunate-amodiaquine (AS-AQ) and artemether-lumefantrine (AL) are first- and second-line treatments for uncomplicated Plasmodium falciparum malaria in Gabon. AL remains highly efficacious, but its widespread us...

Sydney Maghendji-Nzondo, Lady-Charlène Kouna, Gaël Mourembou, Larson Boundenga, Romeo-Karl Imboumy-Limoukou, Pierre-Blaise Matsiegui, Rella Manego-Zoleko, Bertrand Mbatchi, Didier Raoult, Fousseyni Toure-Ndouo and Jean Bernard Lekana-Douki

Malaria Journal 2016 15:420


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