A comparison of malaria prevalence, control and management strategies in irrigated and non-irrigated areas in eastern Kenya
This study was conducted in Bura irrigation scheme in Tana River County and the pastoral area in Ijara, Garissa County in the eastern Kenya to establish the knowledge, attitude and practices on malaria transmi...
John Muthii Muriuki, Philip Kitala, Gerald Muchemi, Ian Njeru, Joan Karanja and Bernard Bett
Malaria Journal 2016 15:402
Despite advances in diagnostic technology, significant gaps remain in access to malaria diagnosis. Accurate diagnosis and misdiagnosis leads to unnecessary waste of resources, poor disease management, and cont...
David Bell, Alessandra E. Fleurent, Michael C. Hegg, John D. Boomgard and Caitlin C. McConnico
Malaria Journal 2016 15:406
A framework for evaluating the costs of malaria elimination interventions: an application to reactive case detection in Southern Province of Zambia, 2014
This paper summarizes a framework for evaluating the costs of malaria elimination interventions and applies this approach to one key component of the elimination strategy—reactive case detection (RCD)—implemen...
Bruce A. Larson, Thandiwe Ngoma, Kafula Silumbe, Marie-Reine I. Rutagwera, Busiku Hamainza, Anna M. Winters, John M. Miller and Callie A. Scott
Malaria Journal 2016 15:408
Assessment of Pfs25 expressed from multiple soluble expression platforms for use as transmission-blocking vaccine candidates
Transmission-blocking vaccines (TBVs) have become a focus of strategies to control and eventually eliminate malaria as they target the entry of sexual stage into the Anopheles stephensi mosquito thereby preventin...
Shwu-Maan Lee, Chia-Kuei Wu, Jordan Plieskatt, David H. McAdams, Kazutoyo Miura, Chris Ockenhouse and C. Richter King
Malaria Journal 2016 15:405
The challenge of using intermittent preventive therapy with sulfadoxine/ pyrimethamine among pregnant women in Uganda
The Uganda National Malaria Control Programme recommends the use of intermittent preventive therapy in pregnancy with sulfadoxine/pyrimethamine (SP) to prevent malaria, however, there is overwhelming evidence ...
Humphrey Wanzira, Henry Katamba, Allen Eva Okullo and Denis Rubahika
Malaria Journal 2016 15:401
A qualitative review of implementer perceptions of the national community-level malaria surveillance system in Southern Province, Zambia
Parts of Zambia with very low malaria parasite prevalence and high coverage of vector control interventions are targeted for malaria elimination through a series of interventions including reactive case detect...
Lynne Lohfeld, Tokozile Kangombe-Ngwenya, Anna M. Winters, Zunda Chisha, Busiku Hamainza, Mulakwa Kamuliwo, John M. Miller, Matthew Burns and Daniel J. Bridges
Malaria Journal 2016 15:400
Diagnosis and treatment based on quantitative PCR after controlled human malaria infection
Controlled human malaria infection (CHMI) has become well-established in the evaluation of drugs and vaccines. Anti-malarial treatment is usually initiated when thick blood smears are positive by microscopy. T...
Jona Walk, Remko Schats, Marijke C. C. Langenberg, Isaie J. Reuling, Karina Teelen, Meta Roestenberg, Cornelus C. Hermsen, Leo G. Visser and Robert W. Sauerwein
Malaria Journal 2016 15:398
Direct transfer of HRPII-magnetic bead complexes to malaria rapid diagnostic tests significantly improves test sensitivity
The characteristic ease of use, rapid time to result, and low cost of malaria rapid diagnostic tests (RDTs) promote their widespread use at the point-of-care for malaria detection and surveillance. However, in...
Keersten M. Ricks, Nicholas M. Adams, Thomas F. Scherr, Frederick R. Haselton and David W. Wright
Malaria Journal 2016 15:399
Integrated paediatric fever management and antibiotic over-treatment in Malawi health facilities: data mining a national facility census
There are growing concerns about irrational antibiotic prescription practices in the era of test-based malaria case management. This study assessed integrated paediatric fever management using malaria rapid di...
Emily White Johansson, Katarina Ekholm Selling, Humphreys Nsona, Bonnie Mappin, Peter W. Gething, Max Petzold, Stefan Swartling Peterson and Helena Hildenwall
Malaria Journal 2016 15:396
Anti-erythrocyte antibodies may contribute to anaemia in Plasmodium vivax malaria by decreasing red blood cell deformability and increasing erythrophagocytosis
Plasmodium vivax accounts for the majority of human malaria infections outside Africa and is being increasingly associated in fatal outcomes with anaemia as one of the major complicati...
Luiza Carvalho Mourão, Paula Magda da Silva Roma, Jamila da Silva Sultane Aboobacar, Camila Maia Pantuzzo Medeiros, Zélia Barbosa de Almeida, Cor Jesus Fernandes Fontes, Ubirajara Agero, Oscar Nassif de Mesquita, Marcelo Porto Bemquerer and Érika Martins Braga
Malaria Journal 2016 15:397
Low prevalence of dihydro folate reductase (dhfr) and dihydropteroate synthase (dhps) quadruple and quintuple mutant alleles associated with SP resistance in Plasmodium vivax isolates of West Bengal, India
Emergence of chloroquine resistant Plasmodium vivax is a serious obstacle towards malaria control in India. This study elucidates the temporal pattern of antifolate [sulfadoxine–pyrimethamine (SP)] resistance in
Sabyasachi Das, Abhijit Banik, Amiya Kumar Hati and Somenath Roy
Malaria Journal 2016 15:395
Low prevalence of dihydro folate reductase (dhfr) and dihydropteroate synthase (dhps) quadruple and quintuple mutant alleles associated with SP resistance in Plasmodium vivax isolates of West Bengal, India
Emergence of chloroquine resistant Plasmodium vivax is a serious obstacle towards malaria control in India. This study elucidates the temporal pattern of antifolate [sulfadoxine–pyrimethamine (SP)] resistance in
Sabyasachi Das, Abhijit Banik, Amiya Kumar Hati and Somenath Roy
Malaria Journal 2016 15:395
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