Csir young scientist awards

RESUME

1. Name of the nominee in Full : SOUNDARAPANDIAN KANNAN

  2. (a) Date and place of birth) : 27-06-1972, Sivakasi

(b) Nationality : INDIAN

(c) Gender : MALE

3. Address with Telephone / Mobile / Fax / e-mail:
  (a) Complete Official : Professor and Head,

Department of Zoology,

Periyar University,

Salem- 636011

TAMIL NADU

Tel. Phone : [phone] (Extn: 335)

Fax :[phone]

[e-mail]

[e-mail]
(b) Residential Address: : 1/3 VASNTHA NIVAS,

Kattuvattam, Panagadu, Saminayakkanpatti (P.O),

Salem-636 011, TN

Permanent Address : 1/200B Wattson Illam, Guru Colony, Oppt. To TNHB,

SIVAKASI (West) -626124, TN

Phone: [phone] (Residence)

(c) Mobile : [phone]

(d) email : [e-mail]

4. Field of specialization: Cancer Biology, Nanodrug, Cancer Nanomedicine

5. Academic Qualifications

S.No	Degree	Subject	Class CGP Marks	Year	University	Additional Particulars
1	B.Sc.,	Zoology (Main) Botany Chemistry	I-Class 70.09%	1992	Madurai Kamaraj University	-
2	M.Sc.,	Zoology	I- Class with Distinction 77.2%	1994	Madurai Kamaraj University	II Rank
3	Ph. D. (Zoology) Histomorphology Biochemistry and Chemical identification of rat scent glands in relation to rodent pest management: A New light In IPM Programme (Guide: Prof. G. Archunan)		Highly Commented	1998	Bharathidasan University	Highly commended
4	Ph D (Biotechnology) Molecular Cloning and Proteomic Analysis of Mouse V2Rx Receptor (Guide: Prof. M. Krishnan)		Highly Commented	2012	Bharathidasan University	Highly Commended
5	DBT-PDF/ RA		Development of Immuno Contraceptive Vaccine.	1997-99	MRDG-Indian Institute of Science Bangalore	DBT
6	DST-Young Scientist		Micro-sequencing of Pheromone Receptor	2000-03	ANJA College (Affiliated with MKU)	Completed & Report Submitted
7	DBT Overseas Associateship (On deputation service)		Genomic organization of V2Rx Receptor	2005-06	University of Birmingham & University of Leeds, UK	Completed & Report Submitted
8	UGC-RAMAN Fellowship		Cancer Biology	2016-2017	--	Selected

Date of joining in the Institution (Designation & Scale): 12^th Aug 2013, Professor (Direct),

Basic Pay-Rs. 46,230+10000 GP+ other allowances

7. Positions held

S No	Period	Place of Employment	Designation	Scale of pay
1	June 1999-Dec 2008	ANJA, College (Autonomous), Sivakasi	Asst. Professor, Reader & Head i/c	Rs. 8000+ Other Allowances Rs. 12000+ other allowances
2	Jan 2009-Aug 2013	Bharathiar University, Coimbatore	Asst. Professor in Zoology, and Coordinator of Human Molecular Genetics Course	Rs. 18850+ 7000+ Other allowances
3	Aug 2013- Till date	Periyar University, Salem	Professor & Head, Zoology	Rs. 46230+10000+ other allowances

8. Details of Fellowship / Associateship held, if any or from other sources/ agencies.

CSIR-SRF awarded in March 1995- July 1998

DBT-PDF August 1997- June 1999 (Prof. P.R.Adiga’s Lab, IISc)

DST- Young Scientist: April2000- March2003

DBT – Overseas Associateship (UK) - 2005-2006(Univ of Birmingham)

Welcome Trust PDF 2006-2007 (Univ. of Leeds)

UGC-Raman Post Doctoral Fellowship for Research in USA 2016-2017
9. Significant foreign assignments

S No	Period of visit		Institute/ country visited	Purpose of visit
	From	To
	July 2016	June 2017	US Institution Not yet selected	UGC-Raman PDF- Sanctioned Project
	28-01-2016	29-01-2016	4^th International Congress on Nanoscience and Nanotechnology held at Malaysia	Invited Speaker Catherin Mediated Endocytosis of Nano formulated Drug to target Breast Cancer
	18.06.2014	19-06-2014	Korean Association of Cancer Seoul, Korea	Invited lecture on Nanotherapy for lung cancer
	9-7-2012	11-7-2012	Institute of Zoology Germany	To present research findings in the International Conference
	03-04-2011	07-04-2011	Bloemfontein, South Africa	To present research findings in the International Conference
	09-09-2011	13-09-2011	University College London, UK	To present research findings in the International Conference
	24-08- 2010	27-08-2010	Gifu University, JAPAN	INVITED TALK in the International Conference
	01-05- 2010	30-06-2010	National University of Singapore	Research Training
	09-06-2009	11-06-2009	Chinese Academy of Sciences, Institute of Zoology China	To present research findings in the International Conference
	01-06-2006	31-07-2007	University of Birmingham (Under Prof. Stephen John William Busby, FRS) UK	Welcome Trust Scheme Post Doctoral Fellow
	09-02-2006	14-02-2006	Arizona State University	To present research findings in the International Conference
	01-08-2005	31-05-2006	University of Leeds (Under Prof. David Beech FRS) and University of Birmingham (Under Prof. Stephen John William Busby, FRS) UK	Research Associate
	21-09-1996	03-01-1997	University of Hertfordshire (Under Prof. John M. Walker)	Part of Ph.D work

10. Significant contributions to science and/ or technology development
The contributions of Prof. S.Kannan in development of enhanced smart delivery of gene / drugs of interest to target cancers are appreciable. His study has firstly demonstrated the presence of a target for the development of therapeutic agents for lung and breast cancers, namely cytosolic phospholipase A2α (cPLA2α) and Cycloxiginase 2. Secondly, target validation of cPLA2α and COX2 have been performed with a view to the development of highly specific, tumour directed anticancer drug deliver such as enzyme inhibitors and enzyme-targeted prodrugs namely Pyrrolidine-2 and Doxorubicin loaded antibody dependent nanoparticles etc.
He also formulated multifunctional magnetic polymers nano-combination which is gaining more importance in cancer nanotheranostics due to their safety and their potential in delivering targeted functions. Further, they prepared the chitosan– silver–phycoerythrin nanocomposites (CS–Ag–PE NCs) to target breast cancer. These cancer nanotheranostic materials are useful in real-time monitoring of drug delivery and therapeutic action against tumor cells as they co-deliver therapeutic and imaging functions. They also reported that the use of natural fluorescent protein (R-phycoerythrin (PE)) in the preparation of novel multifunctional CS–Ag–PE NCs and the theranostic potentials of the synthesized nanocomposites (NCs) are the major contribution of his laboratory which have been evaluated against triple negative breast cancer (MDA-MB-231) cells which showed a promising results. The nanotherapeutic approach introduced by Kannan’s lab supports to develop tumor targeted nanocore/ nanopolymers with a pH dependent induction of apoptosis. He laid a strong foundation in understanding Cancer Nano-Theranostics.

1. 
   Summarise the most significant work of the nominee on which the recommendation is based
   

(in 50 words):
The applicant’s laboratory is deeply concentrating on development of biologically safe medicine for cancer and adopted innovative method to synthesize the nanocarriers for smart drug/ gene delivery. In particular, metal nanoparticles have been synthesized and tailor made according to our need based to improve the targeted drug delivery.
(b). Names of the industries in which the technology (ie) has (have) been used (give the production

figures of products):

M/s Sigma Aldrich, Provided citations for our methodologies to extract products like, Santal wood oil/natural oil, Fucoidan, R-Phycoerythrin, applications of 1-Aminoanthracene

1. 
   Paulpandi, M, Kannan, S, Thangam, R, Kaveri, K, Gunasekaran, P, Rejeeth, C, 2012. In vitro anti-viral effect of β-santalol against influenza viral replication. Phytomedicine, 19: 231-235.
   

2. 
   Suresh, V, Anbazhagan, C, Thangam, R, Senthil Kumar, D, Senthil Kumar, N, Kannan, S, Rengasamy, R, Palani, P. 2013. Stabilization of mitochondrial and microsomal function of fucoidan from Sargassum plagiophyllum in diethylnitrosamine induced hepatocarcinogenesis. Carbohydrate Polymers, 92:1377-1385.
   

3. 
   Senthilkumar, N, Suresh, V, Thangam, R, Kurinjimalar, C, Kavitha, G, Murugan, P, Kannan, S, Rengasamy, R, 2013 Isolation and characterization of macromolecular protein R-Phycoerythrin from Portieria hornemannii. International Journal of Biological Macromolecules, 55: 150–160.
   

4. 
   S. Kannan, P. Mareeswaran, M.Krishnan, S. Achiraman, Neil Spencer, B. Florence Nitingel 2011, Properties of mouse vomeronsasl receptor and assment of its role in pheromone signaling. Rapid Communication in Mass Spectrometry 25: 1-9.
   

11. Delivered invited lecture(s) in India / abroad and/ or chaired any scientific International Conference Symposium (give details):