Single nucleotide polymorphisms (SNPs) are the most common type of genetic variation and represent over 80% of the genetic variation between individuals. SNPs are ideal candidates for research correlating phenotype and genotype. Since some SNPs predispose individuals to a certain disease or a trait or cause an altered reaction to a drug, they are proving to be highly useful in diagnostics and drug development. With more than 1.8 million genetic markers, Affymetrix’ SNP 6.0 array provides high-performance, high-powered and low-cost genotyping. It is now available from Asuragen. In combination with Asuragen’s service expertise you have the tools to carry out a whole-genome study and bring power to your research.
SNP array 6.0 contains probes for more than 906,600 single nucleotide polymorphisms (SNPs) and more than 946,000 probes for the detection of copy number variation (CNV). This corresponds to a median inter-marker distance in the genome of less than 700 nucleotides. Again, the analysis will start from the “.CEL” files, which allows maximum flexibility in the choice of the algorithms for CNV genotyping.
