Department of anaessthesia

POSTGRADUATE

MMed

1

Research Fields and Staff
PERMANENT STAFF
Miss G Boltman – Chief Radiographer, Lecturer and Administration

Sentinel node imaging and Radioguided occult lesion localization

Mr J Boniaszczuk – Chief Radiographer, Lecturer and Administration

Equipment and quality assurance

Mrs P Freedman – Chief Radiographer & Lecturer

Gastrointestinal tract

Mrs Z Banderker – Chief Radiographer

Miss M Adams – Chief Radiographer

Mr T R Geldenhuys – Chief Radiographer

Mrs S Ismail – Senior Radiographer

Mrs L Bewerunge – Part-time Senior Radiographer- Osteodensitometry

Mrs S M Bird - Part-time Chief Medical Technologist & Lecturer

Contact Details

Postal address: Division of Nuclear Medicine, Groote Schuur Hospital & University of Cape Town, Observatory 7925

Telephone: [phone]

Fax: [phone]

E mail: [e-mail]
DEPARTMENT OF RADIATION MEDICINE

DIVISION OF RADIATION ONCOLOGY

Head of Division - Professor R P Abratt
Divisional Profile
1. The Division of Radiation Oncology provides the following services:

1.1 Investigation, management and treatment of all forms of malignant disease. This is co-ordinated by 23 multidisciplinary clinics, which meet weekly.

1.2 Participation in drug-related clinical studies, both national and international.

1.3 Maintenance of cancer registries monitoring cancer incidences and epidemiological characteristics.

1.4 National referral treatment centre for retinoblastoma and ocular malignant melanoma
2. Teaching of undergraduate medical courses and provision of post graduate specialists training courses. Pre and post-diplomate instruction to radiographers and post-diplomate courses to nurses. Full training in Radiobiology from under-graduate to honours, masters and doctoral level.
3. Provision of a comprehensive clinical radiobiological research facility.

Divisional Statistics
PERMANENT AND LONG TERM CONTRACT STAFF
JMS STAFF

Professors 1

1

UNIVERSITY STAFF

Research Staff	6
Administrative/Clerical Staff	1
Subtotal	7

JOINT STAFF (UCT/PGWC)

Principal Specialist /Associate Professor	1
Senior Full-time Lecturers	3
Lecturers	4
Principal Medical Officers	1
Sessional Medical Officers	2
Subtotal	11

Total 19

HONORARY STAFF

Honorary Lecturers 3

1 3

POSTGRADUATE STUDENTS

Registrars

12

Research Fields and Staff
PERMANENT STAFF
Specialist Staff
Professor Raymond Abratt

Chief Specialist Radiation Oncology & Head of Division; Main interests - Lung

Cancer; Male Genito-urinary Tract Cancer.
Professor Clare Stannard

Senior Specialist Radiation Oncology & Senior Lecturer; Main interests - Head & Neck Cancer, Tumours of the Eye, Neutron & Proton Therapy.

Dr Krystyna Marszalek

Speicalist Radiation Oncology and Lecturer; Main interests - Lung Cancer; Male Genito-urinary Tract Cancer.

Dr Zainab Mohamed

Specialist Radiation Oncology and Senior Lecturer; Main interests - Lymphoma, Myeloma, Melanoma, Hodgkin’s disease

Dr Elizabeth Murray

Senior Specialist Radiation Oncology & Senior Lecturer; Main interests - Breast Cancer.

Dr Jeanette Parkes

Senior Specialist Radiation Oncology and Senior Lecturer; Main interests - neurological tumours, paediatric tumours, bones and sarcoma

Dr Barbara Robertson

Specialist Radiation Oncology & Lecturer; Main interests - Thyroid, Oesophageal and

Gastro-intestinal cancers, stomach, pancreas, liver, unknown primary cancers.
Dr Leon Van Wijk

Senior Specialist Radiation Oncology & Senior Lecturer; Main interests - Gynaecological tumours.

Dr Julie Wetter

Specialist Radiation Oncology and Lecturer; Main interests – skin cancers, melanoma

Medical Officers
Dr Cindy Shepherd

Principal Medical Officer Radiation Oncology; Main interests - Lung cancer, Tumours of the thyroid, Male genito-urinary tract cancer.

Scientific Staff
Dr Andre Hendrikse

Senior Medical Natural Scientist & Lecturer; Main interest - Research in Medical Natural Science Radiobiology (research on tumours with experimental animals)

Dr Alistair Hunter

Medical Natural Scientist; Main interest - Research in Medical Natural Science Radiobiology (research on tumours with experimental animals)

CONTRACT RESEARCH STAFF
PART-TIME CLERICAL RESEARCH ASSISTANTS (DATA MANAGERS)

Mrs Helen Basset

Data manager for Dr B Robertson. Main interests – Colorectal Cancer.

Mrs Glynis Chilcott

Data manager for Professor R Abratt. Main interests - Lung Cancer, Male Genito-urinary Tract Cancer.
Mrs Sue Giles

Data manager for Dr Murray. Main interest - Breast Cancer.

Mrs E McEvoy

Data manager for Dr Murray. Main interest - Breast Cancer.

Miss E Nel

Data manager for Dr Murray. Main interest - Breast Cancer.
Mrs Jean Wilmot

Data manager for Professor R Abratt. Main interests - Lung Cancer, Male Genito-urinary Tract Cancer.

HONORARY LECTURERS
Professor I D Werner

Emeritus Professor/Specialist Radiation Oncology.

Contact Details

Postal address: Division of Radiation Oncology, Groote Schuur Hospital & University of Cape Town, Observatory 7925, South Africa

Telephone: [phone]
Fax: [phone]
E-mail: [e-mail]

DEPARTMENT OF RADIATION MEDICINE

DIVISION OF RADIOLOGY

Head of Division: Professor Stephen James Beningfield
Divisional Profile
The Division of Radiology is involved at Groote Schuur, Red Cross, GF Jooste and Somerset Hospitals, as well as in professional activity linked to Victoria Hospital and the Day Hospitals. Diverse multidisciplinary units involve medical, surgical, neuroradiology, head and neck, thoracic, hepatobiliary, vascular, interventional, trauma, urological, abdominal and paediatric imaging. These all have service, academic and collaborative research commitments. A number of trials in conjunction with Radiation Oncology, Medicine, Surgery and other departments are on-going. The Magnetic Resonance Imaging, multislice CT and Statscan scanners have led to further teaching and research activity. A joint 3T MRI is being installed at Tygerberg Hospital. Members of the Division are actively participating in the UCT Private Academic Hospital.
The division retains a core of senior experienced members. Dr M Garb, Principal Specialist, retired at the end of October and Dr Paul Kitsa left the division in May to join private practice in Johannesburg.
Professors Goodman, Handler and Kottler continue to provide valuable sessional input in thoracic imaging, neuroradiology and mammography.
Cape Town was host to the 24^th International Congress of Radiology which was held at the Cape Town Convention Centre from 12-16 September. Prof Beningfield coordinated the abdominal imaging track. Many staff from this university presented papers, as did many ex-members of staff who are now based all over the world.
The Film Librarian post was filled by Mr Sipho Mamputha in February 2006.
Divisional Statistics
Permanent and long-term contract staff
University staff

Professor and Head of Division	1
Administrative Staff	1
Total	2

JMS Staff

Senior Lecturers	6
Lecturers	3
Total	9

Part-time JMS Staff

Emeritus Professor	1
Associate Professors	2
Senior Specialist	1
Total	4

Part-time UCT Staff

Film Librarian

1

Students

Masters [registrars]

22 *

* This includes 3 unpaid supernumerary registrars from African countries [Sierra Leone, Ghana and Namibia] whose training is sponsored, and one registrar seconded from Mthatha University.

Research Fields and Staff
Professor Stephen Beningfield

Hepatobiliary, vascular, interventive radiology, computer applications and digital radiology

Dr Nazir Ahmed

Cross-sectional imaging, colorectal imaging

Dr Glenda Albuquerque-Jonathan

Cross-sectional imaging, mammography and musculo-skeletal imaging

Dr Helen Ball

Ultrasound, mammography, computerised tomography and urological radiology

Dr Sally Candy

Neuroradiology and magnetic resonance

Dr Minnie Garb

Head and neck radiology, ear nose and throat imaging

Professor Hillel Goodman

Chest radiology, high-resolution computerised tomography and fine needle biopsies

Professor Leonard Handler

Neuroradiology

Dr Tracy Kilborn

Paediatric radiology

Dr Paul Kitsa

Interventive radiology

Professor Ronald Kottler

Mammography, gastrointestinal radiology

Dr Sulaiman Moosa

Cardiac magnetic resonance imaging

Dr Richard Pitcher

Paediatric radiology

Dr Robert Seggie

Ultrasound, computerised tomography and general radiology

Dr Nicole Wieselthaler

Paediatric radiology

Distinguished visitors
Dr Abdul Gaffor Al-Ansaria

New Zealand

Dr Shadley Fataar

Australia

Dr Bruce Foster

United States of America

Dr Lawrence Friedman

Canada
Dr Michael Gottlieb

United Kingdom
Professor Anne Osborn

United States of America

Dr Christopher Welman

Perth, Australia

Contact Details

Postal Address: Division of Radiology, C16, Groote Schuur Hospital, Private Bag,

Observatory, 7935

Telephone: [phone] or 406 6426

Fax: [phone]

E-mail: [e-mail]

Department of Radiation Medicine
Research Output
ARTICLES IN PEER-REVIEWED JOURNALS
Abratt, R.P. and Hart, G.J. 2006. 10-year update on chemotherapy for non-small cell lung cancer. Annals of Oncology, 17(Supplement 5): v33-v36.
Abratt, R.P., Lehnert, M., Lee, J.S., Han, J.Y., Tsai, C.M., Boyer, M., Mok, T., Kim, S.W., Lee, J.S., Brnabic, A.J.M. and Reece, W.H.H. 2006. Phase II trial of gemcitabine-carboplatin-paclitaxel as neoadjuvant chemotherapy for operable non-small cell lung cancer. Journal of Thoracic Oncology, 1(2): 135-140.
Andronikou, S., Wieselthaler, N. and Fieggen, A.G. 2006. Cervical spina bifida cystica: MRI differentiation of the subtypes in children. Child's Nervous System, 22(4): 379-384.
Beningfield, S.J. 2006. Long-term transplant liver biliary access with a silastic 'O' tube. South African Journal of Radiology, 10(4): 26-27.
Beningfield, S.J. 2006. Interventive radiology in portal hypertension. South African Journal of Radiology, 10(4): 18-23.
Beningfield, S.J. 2006. ISR Congress: Cape Town 2006. South African Journal of Radiology, 10(4): 2.
Beningfield, S.J. 2006. Liver biopsy - the current view? South African Journal of Radiology, 10(4): 4-6.
Beningfield, S.J. 2006. The HPBASA inaugural meeting. South African Journal of Radiology, 10(4): 39.
Davidson, A., Desai, F., Stannard, C.E., Ivey, A.T., Solomons, R. and Sinclair-Smith, C.C. 2006. Intraocular rhabdomyosarcoma in the sibling of a patient with a cerebellar medulloepithelioma. Journal of Pediatric Hematology Oncology, 28: 476-478.
Freedman, P.N., Goldberg, P.A., Fataar, A.B. and Mann, M.D. 2006. A comparison of methods of assessment of scintigraphic colon transit. Journal of Nuclear Medicine Technology, 34(2): 76-81.
Greyling, P.J., Andronikou, S., Ackermann, C., Schulze, O.C. and Wieselthaler, N. 2006. Rhabdomyosarcoma - site matters. South African Journal of Radiology, 10(4): 8-13.
Hunter, A.J., Hendrikse, A.S., Renan, M. and Abratt, R.P. 2006. Does the tumor microenvironment influence radiation-induced apoptosis? Apoptosis, 11(10): 1727-1735.
International Breast Cancer Study Group (including E.M. Murray, I.D. Werner, D.M. Dent and E. Panieri). 2006. A randomized trial comparing axillary clearance versus no axillary clearance in older patients with breast cancer: First results of International breast Cancer Study Group Trial 10-93. Journal of Clinical Oncology, 24: 337-344.
International Breast Cancer Study Group (including E.M. Murray, I.D. Werner, D.M. Dent and E. Panieri). 2006. Tamoxifen after adjuvant chemotherapy for Premenopausal women with lymph node-positive breast cancer IBCSG Trial 13-93. Journal of Clinical Oncology, 24: 1332-1341.
Jonas, N.E., Fagan, J., Thandar, M., Pitcher, R. and Fagan, J.J. 2006. Primary neuroblastoma: A rare cause of a retropharyngeal mass in a neonate. Journal of Laryngology and Otology, 1(E15): 1-3.
Jonathan, G. 2006. Atypical tuberculosis of the knee joint. South African Journal of Radiology, 10(4): 28.
Karpelowsky, J.S., Wieselthaler, N. and Rode, H. 2006. Primary paraesophageal hernia in children. Journal of Pediatric Surgery, 41(9): 1588-1593.
Koning, L., Douglas, T., Pitcher, R. and Van As, A.B. 2006. Short emergency department length of stay attributed to full-body digital radiography - a review of 3 paediatric cases. South African Medical Journal, 96(7): 613 - 614.
Krige, J.E. and Beningfield, S.J. 2006. Delayed presentation of haemobilia after penetrating liver injury (Letter to the editor). HPB Surgery, 8(3): 235.
Krige, J.E. and Beningfield, S.J. 2006. Liver resection for complicated hepatolithiasis (Letter to the editor). Archives of Surgery, 141: 713-714.
Krige, J.E. and Beningfield, S.J. 2006. Subcutaneous tunnel and hepatocholangioplasty after resection for intrahepatic stones (Letter to the editor). Hepatobilary and Pancreatic Diseases International, 5(3): 474-475.
Krige, J.E. and Beningfield, S.J. 2006. The new DEAL - a novel technique using a double-entry access loop to facilitate bilateral intrahepatic biliary access for complex intrahepatic stones. South African Journal of Surgery, 44(2): 56-58.
Mnguni, P. 2006. Vascular lesions associated with HIV. South African Journal of Radiology, 10(4): 14-17.
Moosa, S.E. and Andronikou, S. 2006. Spastic quadraparesis following a relatively minor injury - the 'os odontoideum'. South African Journal of Radiology, 10(3): 34-36.
Morrow, B., Hatherill, M., Smuts, H.E.M., Yeats, J., Pitcher, R. and Argent, A.C. 2006. Clinical course of hospitalised children infected with human metapneumovirus and respiratory syncytial virus. Journal of Paediatrics and Child Health, 42(4): 174-178.
Pestalozzi, B.C., Zahrieh, D., Price, K., Holmberg, S.B., Lindtner, J., Collins, J., Crivellari, D., Fey, M., Murray, E.M., Pagani, O., Simonici, E., Castiglione-Gertsch, M., Gelber, R.D., Coates, A. and Goldhirsch, A., 2006. Identifying breast cancer patients at risk foro Central Nervous System (CNS) metastases in trials of the International Breast Cancer Study Group (IBCSG). Annals of Oncology, 17(6): 935-944.
Ramlau, R., Gervais, R., Krzakowski, M., Von Pawel, J., Kaukel, E., Abratt, R.P., Dharan, B., Grotzinger, K., Ross, G., Dane, G. and Shepherd, F. 2006. Phase III study comparing oral topotecan to intravenous docetaxel in patients with pretreated advanced non-small cell lung cancer. Journal of Clinical Oncology, 24(18): 2800-2807.
Said-Hartley, Q.M., Candy, S. and Said-Hartley, Q. 2006. Hyperparathyroidism with presumed sellar-parasellar brown tumour based on imaging findings. South African Journal of Radiology, 10(4): 29-30.
Tipping, B., De Villiers, L., Candy, S. and Wainwright, H.C. 2006. Stroke caused by Human Immunodeficiency Virus-associated intracranial large-vessel aneurysmal vasculopathy. Archives of Neurology, 63: 1640-1642.
Van As, A.B., Douglas, T., Kilborn, T., Pitcher, R. and Rode, H. 2006. Multiple injuries diagnosed using full-body digital x-ray. Journal of Pediatric Surgery, 41(7): 25-28.
Van As, A.B., Van Loghem, A.J., Biermans, B.F.J., Douglas, T., Wieselthaler, N. and Naidoo, S. 2006. Causes and distribution of facial fractures in a group of South African children and the value of computed tomography in their assessment. International Journal of Oral and Maxillofacial Surgery, 35: 903-906.
Van der Weert, E.M., Hartgers, N.M., Schaaf, H.S., Eley, B.S., Pitcher, R., Wieselthaler, N., Laubscher, R., Donald, P.R. and Schoeman, F. 2006. Comparison of diagnostic criteria of tuberculous meningitis in human immunodeficiency virus - infected and uninfected children. The Pediatric Infectious Disease Journal, 25(1): 65-69.
Zar, H.J., Mcivor, B., Furlan, G.L., Jedeiken, L. and Pitcher, R. 2006. Congenital lung mass in an asymptomatic patient. South African Medical Journal, 96(6): 512-513.

BOOKS
Andronikou, S., Wieselthaler, N. and Kilborn, T. (eds) 2006. See right through me. An imaging anatomy atlas: 505. Cape Town: SAMA Health and Medical Publishing Group.

CHAPTERS IN BOOKS
Andronikou, S., Wieselthaler, N., Kilborn, T. and Strachan, M. 2006. Paediatrics. In S. Andronikou, N. Wieselthaler and T. Kilborn (eds), See right through me. An imaging anatomy atlas: 418-505. Cape Town, South Africa: SAMA Health and Medical PUblishing Group.
Beningfield, S.J. 2006. Biliary tree and pancreatic duct system. In S. Andronikou, N. Wieselthaler and T. Kilborn (eds), See right through me: An imaging anatomy atlas: 256-262. Cape Town, South Africa: SAMA Health and Medical Publishing Group.
Beningfield, S.J. and Andronikou, S. 2006. The brain. In S. Andronikou, N. Wieselthaler and T. Kilborn (eds), See right through me: An imaging anatomy atlas: 2-22. Cape Town, South Africa: SAMA Health and Medical Publishing Group.
Candy, S. 2006. Cerebral vessels. In S. Andronikou, N. Wieselthaler and T. Kilborn (eds), See right through me: An imaging anatomy atlas: 28-34. Cape Town, South Africa: SAMA Health and Medical Publishing Group.
Chhiba, D. and Chhiba, D. 2006. The liver. In S. Andronikou, N. Wieselthaler and T. Kilborn (eds), See right through me: An imaging anatomy atlas: 246-255. Cape Town, South Africa: SAMA Health and Medical Publishing Group.
Eshun, A.A. and Eshu, A.A. 2006. The pelvis. In S. Andronikou, N. Wieselthaler and T. Kilborn (eds), See right through me: An imaging anatomy atlas: 372-379. Cape Town, South Africa: SAMAS Health and Medical Publishing Group.
Furlan, G.L., Mcivor, B. and Mckenzie, C.A. 2006. Renal tract. In S. Andronikou, N. Wieselthaler and T. Kilborn (eds), See right through me. An imaging anatomy atlas: 289-299. Cape Town, South Africa: SAMA Health and Medical Publishing Group.
Krige, J.E., Beningfield, S.J. and Bornman, P.C. 2006. Liver and portal circulation, K. G. Burnanad, A. E. Young, J. Rowlands, J. Scholefield and J. Lucas (eds) New Aird's companion in Surgical studies: 683-707*. London: Churchill Livingstone.
Krige, J.E., Beningfield, S.J. and Bornman, P.C. 2006. Management strategies in pancreatic trauma. In C.D. Johson and I. Taylor (eds), Recent advances in surgery: 95-117. London: Royal Society of Medicine Press Ltd.
Krige, J.E.J., Beningfield, S.J. and Bornman, P.C. 2006. Management strategies in pancreatic trauma. In C.D. Johnson and I. Taylor (eds), Recent advances in surgery: 95-117. London, United Kingdom: Royal Society of Medicine Press Ltd.
Mdunge, N.S. and Mdunge, N.S.M. 2006. Pancreas and spleen. In S. Andronikou, N. Wieselthaler and T. Kilborn (eds), See right through me: An imaging anatomy atlas: 263-267. Cape Town, South Africa: SAMA Health an Medical Publishing Group.
Pitcher, R., Wieselthaler, N., Kilborn, T. and Furlan, G.L. 2006. Radiographic assessment. In A.B. van As and S. Naidoo (eds), Paediatric trauma and child abuse: 141-150. Southern Africa: Oxford University Press.
Theron, S., Lotz, J. and Beningfield, S.J. 2006. Spinal cord. In S. Andronikou, N. Wieselthaler and T. Kilborn (eds), See right through me: An imaging anatomy atlas: 60-66. Cape Town, South Africa: SAMA Health and Medical Publishing Group.
Van den Heever, A., Jonathan, G., Du Plessis, J., De Villiers, R., Brandt, A. and Andronikou, S. 2006. Upper limb. In S. Andronikou, N. Wieselthaler and T. Kilborn (eds) See right through me: An imaging anatomy atlas: 312-338. Cape Town, South Africa: SAMA Health and Medi cal PUblishing Group.
Van den Heever, A., Jonathan, G., Von Bezing, H., De Villiers, R., Hayes, M. and Andronikou, S. 2006. Lower limb. In S. Andronikou, N. Wieselthaler and T. Kilborn (eds), See right through me: An imaging anatomy atlas: 339-371. Cape Town, South Africa: SAMA Health and Medical Publishing Group.

PUBLISHED CONFERENCE ABSTRACTS
Epstein, D., Dave, J., Albaquerque-Jonathan, G., Levitt, N.S., Watermeyer, G., Fataar, A.B. and Metz, D.C. 2006. Vertebral fracture risk factors in inflammatory bowel disease (IBD) patients at Groote Schuur Hospital, Cape Town. SAMJ 96 (8) : 738.
Hunter, A.J., Hendrikse, A.S., Renan, M. and Abratt, R.P. 2006. The Impact of the Cellular Micro-Environment on Radiation-Induced Apoptosis. Radiotherapy & Oncology 78 (Supplement 1) : S6-S7.
Kilborn, T., Wieselthaler, N., Davidson, A. and Pitcher, R. 2006. Imaging Appearances of HIV Associated Non Hodgkins Lymphoma in Paediatrics. pediatric radiology 36 (S1) : 89.
Kilborn, T., Zampoli, M., Pitcher, R., Wieselthaler, N. and Furlan, G.L. 2006. Immune Reconstitution Inflammatory Syndrome (IRIS) Due to Mycobacterium Tuberculosis Infection in HIV Positive Children on Highly Active Antiretroviral Therapy (HAART) - A South African Perspective. Pediatric Radiology 36 (S1) : 61.
Kilborn, T., Wieselthaler, N., Davidson, A., Pitcher, R. and Furlan, G. 2006. The imaging appearances of HIV associated non-Hodgkin's lymphoma in paediatrics. Proceedings of the International Society of Paediatric Radiology Congress, Montreal, Canada, 89. ISBN 0301-0449.
Tipping, B., De Villiers, L., Candy, S., Wainwright, H.C. and Bryer, A. 2006. Vasculopathy in HIV infected patients with stroke. International Journal of Stroke 1 (Suppl 1) : 39-40.
Van Wijk, A.L., Mbatini, N., Howard, B., Denny, L.A., De Haeck, C.M.C. and Soeters, R.P. 2006. Preventing cervical cancer in developing countries. 11th Biennial meeting of International Gynecologic Cancer Society October 14-18^th CD-ROM.
Wieselthaler, N., Kilborn, T. and Grier, D. 2006. Pprepontine haematoma on CT brain post trauma. An indication for urgent cervical spine MRI. Proceedings of the International Society of Paediatric Radiology Congress, Montreal, Canada, 72.
Zampoli, M., Pitcher, R., Kilborn, T., Wieselthaler, N. and Furlan, G.L. 2006. Immune reconstitution inflammatory sybndrome (IRIS) due to mycobacterium tuberculosis infection in HIV positive children on highly active antiretroviral therapy (HAART) – a South African perspective. Proceedings of the International Society of Paediatric Radiology Congress, Montreal, Canada, 61. ISBN 0301-0449.

UNIVERSITY PUBLICATIONS AND WORKS OF A POPULAR NATURE
Beningfield, S.J. 2006. Clinical pharmacology: Risks of using iodinated contrast material for radiological investigations. CME, 6(24): 328-330.
Dahya, V. 2006. Multidetector Computed Tomography of the Abdomen. CME, 24(6): 322-326.

THESES AND DISSERTATIONS PASSED FOR HIGHER DEGREES
Elhaj, M. 2006. Breast Conservation Treatment At Groote Schuur Hospital: Treatment Outcome: 1-71. MMed Radiation Oncology Dissertation, University of Cape Town.

Department of Surgery

Research Report 2006
(Including the following Divisions/Institutes: General surgery, Cardiothoracic Surgery (including the Cardio-Vascular Research Unit), Neurosurgery, Ophthalmology, Orthopaedic Surgery, Otolaryngology, Plastic, Reconstructive and Maxillo-Facial Surgery, Urology, and Emergency Medicine)


Head of Department: Professor Del Kahn
Departmental Profile
The Department of Surgery comprises the nine Divisions: General Surgery, Cardiothoracic Surgery, Emergency Medicine, Neurosurgery, Ophthalmology, Orthopaedics, Otorhinolaryngology, Plastic Surgery and Urology. Each of the Divisions functions very independently with regard to administration, clinical service, undergraduate and postgraduate teaching, and research. The Special Clinical expertise, research interests, and outstanding achievements over the last year, are documented in the individual divisional profiles.
The Department of Surgery Research Day, organised by Dr Rob Dunn, was a most successful collaboration between the Divisions. Professor PC Bornman delivered the fifth John Terblanche Lecture.

Department of Surgery
Division of General Surgery



Head of Division: Professor Del Kahn
Divisional Profile
The four surgical firms within the Division of General Surgery are responsible for Hepatobiliary Surgery, Surgical Oncology/Endocrine Surgery, Colorectal Surgery, and Vascular Surgery. The Surgical Intensive Care Unit, the Trauma Unit, and the Transplant Unit are also part of the Division. The Division prides itself on maintaining high standards of clinical service, and teaching of both undergraduates and postgraduates. The Division continues to function as a true academic unit, with its members making significant contributions at both local and international meetings, while at the same time maintaining a high research output. Staff shortages and the financial crisis have not limited the productivity of the Division.
Current research interests of Professor Bornman include anti reflux surgery for gastrooesophageal reflux disease and various aspects of pancreatic surgery. Associate Professor Jakes Krige has several research projects in Portal hypertension and diseases of the liver and bile ducts. Associate Professor Lance Michell is involved in an audit of admissions to the Surgical ICU, as well as several multi centre pharmaceutical trials using anti microbials.
The Vascular Unit under Dr Nad Naidoo is undertaking research into carotid artery disease as well as aorto-iliac disease. Genetic aspects of colorectal cancer is the main research interests of Professor Paul Goldberg in the Colorectal unit. Dr Eugene Panieri has a special interest in sentinel lymphnode biopsy in breast cancer as well as problems related to battery acid ingestion. Doctors Andy Nicol and Pradeep Navsaria are involved in major audits of various types of trauma, as well as various prospective randomised studies including penetrating cardiac injuries.

DEPARTMENT OF SURGERY

CHRIS BARNARD DIVISION OF CARDIOTHORACIC SURGERY

(Including the Cardiovascular Research Unit)

Head of Division: Professor Peter Zilla
Divisional Profile
The start of 2006 saw the potential for further nurturing the collaboration between a strong research unit at Medical School and a highly motivated clinical group with generously refurbished hospital wards and suites at Groote Schuur Hospital. However, 2006 failed to deliver on the expected increase in case loading for budgetary reasons eventually leading to an inevitable demotivation of junior staff. Despite this, the positive attitude by consultants and the adherence to a continuing education programme provided an upbeat conclusion. Recently announced further cutbacks in operating slates due to generalized overspending despite promises of ring-fenced budgets enjoyed by cardiac units in other hospitals, however suggests an ominous start to the approaching new year, especially at Red Cross Children’s Hospital with even greater backlogs in elective cases due to the growing number of emergencies there promising to overburden resources to breaking point.
Within the Division’s Cardiovascular Research Unit, our collaboration with a global medical company has continued to mature and expand into a greater diversity of innovative medical solutions to different disease scenarios. Ongoing research into the application of external shape-memory support for saphenous vein bypass grafts concentrated in 2006 on long-term assessment in the coronary position with highly encouraging preclinical results. Similarly, research focusing on the cell biology of the process of neovascularisation has spear-headed our regenerative medicine approach to facilitating the body’s own ability to remodel semi-synthetic prostheses. The year also saw the establishment of a stem cell laboratory which will focus on the use of adipose derived stem cells in conjunction with our regenerative medicine approach in areas including myocardial infarction and diabetes. A dramatic development in 2006 was the successful transition of one of our key research thrusts of the past 15 years, that is the research conducted into the pathological response to bioprosthetic heart valves. Many milestones were achieved over the last decade, both in terms of the mitigation of valve mineralization and in the diminishment of the inflammatory and immune responses. Our attention has now diversified into understanding the mechanisms of in-stent restenosis of coronary vessels with respect to key metabolic disorders, including diabetes and obesity. These disease states are major risk factors for cardiovascular disease and represent a serious and growing challenge to healthcare in this country.
In line with the requirements for the department of Trade and Industry’s THRIP funding, postgraduate training remained a priority in 2006, including continued collaboration with the Faculty of Science. The Cardiovascular Research Unit concluded two three-year THRIP projects in 2006. Interdigitation between our clinical staff and researchers remains a key goal for which the Division continues to strive and served to greatly facilitate both clinical and applied research during 2006. In addition, the Division hosted a successful and well-attended annual Surgical Research Day.
In summary, 2006 showed a strong continuation of our research programme at Medical School and a steady continuation of our clinical activities at Groote Schuur Hospital. The crisis at Red Cross Children’s Hospital where most of our elective surgery continues to be replaced by emergency surgery continues to represent the biggest handicap to our clinical research programme.

Divisional Statistics
Permanent and Long-term Contract Staff
UCT Conditions of service 2006

Professors	1
Research staff – UCT	1
Research staff – Externally financed	15
Technical Support staff	1
Administrative and clerical staff	2
Departmental Assistant	1
Total	21

Provincial conditions of service 2006

Associate Professors	2 (one 5/8)
Senior Lecturers	3
Lecturers	1
Lecturers (part time – sessions)	2 (1/4 each per week)
Research Staff	1
Clinical Scientist	1
Clinical technologist – Perfusion	5 (one 5/8)
Medical Officer	1
Administrative and clerical staff	2
Total	18

Students

Ph.D.	4
M.Med.	5 (+2 Supernumeries)
M.Sc.	2
Diploma Clinical Technology	2
Total	13

Research Fields and Staff

Permanent Staff
Professor P. Zilla - Head of the Chris Barnard Chair and Director Cardiovascular Research Unit; tissue engineering of cardiovascular implants; bioprosthetic heart valves; endothelial cells
Dr Paul Human - Research Director; bioprosthetic heart valves; xenotransplantation; bioprosthesis inflammatory/immune response; calcification
Associate Professor J Brink - Head of Heart- and Lung Transplantation-Clinical Director; off-pump coronary surgery; aortic and mitral valve reparative surgery; thoracic aortic surgery; heart transplantation
Associate Professor K.M. de Groot - Part-time Thoracic Surgery; oesophageal carcinoma; lung carcinoma; surgery for tuberculosis
Dr J. Hewitson - Head of Paediatric cardiothoracic surgery; mitral valve repair surgery; surgery for tuberculosis
Dr G. Walther - Head of Thoracic Surgery; lung volume reduction surgery; thoracic empyema; Myasthenia gravis; surgery for tuberculosis
Mrs. Mona Bracher - Cardiovascular Research Unit; metalloproteinases: role in selective tissue engineering matrices

Contract Staff

Dr Deon Bezuidenhout

Vascular prostheses; polymeric scaffolds; polymeric hydrogels; bioprosthetic heart valves
Dr Neil Davies

Vascular prostheses; tissue engineering; angiogenesis

Dr Thomas Franz

Biomechanical modelling; finite element analysis

Anel Oosthuysen

Bioprosthetic heart valves; polymeric hydrogels

Lawrence Higham

Hydrogel synthesis and modification

Seike Garny

Tissue engineering

Contact Details

Postal Address: Chris Barnard Division of Cardiothoracic Surgery, Room 3.13, Chris Barnard Building, Faculty of Health Sciences, Anzio Road, Observatory, 7925

Telephone: [phone]

Fax: [phone]

E-mail: [e-mail]

Web: http://www.uct.ac.za/depts/cts

DEPARTMENT OF SURGERY

DIVISION OF OTOLARYNGOLOGY

Head of Division: Professor Johan Fagan
Divisional Profile
The Division of Otolaryngology combines an academic hospital service with university teaching, training and research. It provides specialist clinical services to patients in the Western Cape and beyond, and teaches nursing staff-in-training and primary health care medical officers. Its university responsibilities include in-hospital and community-based training of 170 5^th year medical students, teaching of dental and paramedical students, and specialist training of both local graduates and graduates from other countries. An outreach programme supplements the training of students and primary health care workers in the fundamentals of ear care. We place a strong emphasis on clinical research.

Divisional Statistics
Permanent and Long-term Contract Staff

Professors	1
Associate Professors	1
Lecturers	2
Honorary Lecturers	1
Senior Lecturers (part-time)	7
Audiologists	3
Administrative Staff	1
Total	16