Department of anaessthesia

Research Fields and Staff
PERMANENT STAFF
Professor Jonathan Peter - Head of Department

Dysraphism, the tethered spinal cord, spasticity in cerebral palsy, Posterior fossa tumours in children, Hydrocephalus, CNS infection, Head trauma.

Associate Professor Patrick Semple

Pituitary disease, Head trauma, Vascular surgery, Spinal trauma, Brain tumours.

Associate Professor Allan Taylor

Vascular surgery, Stereotactic surgery, Neuronavigational technology development, Neurovascular disorders and Skull Base surgery.

Associate Professor Graham Fieggen

Dysraphism, Stereotactic surgery, Head Trauma, Epilepsy surgery, Paediatric Oncology and Endoscopy.

Dr D Welsh – Lecturer

Spinal surgery, Head trauma and Spinal trauma.

Dr A A Figaji –Lecturer

Paediatric neurotrauma, endoscopy, oncology, dysraphism.

HONORARY PROFESSORS
Professor Jacquez Charl de Villiers

Honorary Consultant; Pituitary disease

Contact Details

Postal address: H-53, Old Main Building, Groote Schuur Hospital, Observatory 7925,

South Africa

Telphone: [phone]

Fax: [phone]

E-mail: [e-mail] or [e-mail]

DEPARTMENT OF SURGERY

DIVISION OF UROLOGY

Head of Division – Professor A R Pontin
Divisional Profile
The Division of Urology is centred in Groote Schuur Hospital but has urological input at Red Cross War Memorial Children’s Hospital, Victoria Hospital Wynberg and Somerset Hospital. At these hospitals outpatient, inpatient and operative urological services are available. Dr John Lazarus is an Acting Consultant at Red Cross War Memorial Children’s Hospital and does once a week sessions at Tygerberg and Groote Schuur Hospitals.
At the recent Societé Internationale d’Urologie Congress held in Cape Town was awarded the Storz Prize for the best Urology Registrar.
Dr Andre van der Merwe was promoted to Senior Specialist. Drs de Bruin and Sinha passed the College of Medicine FC Urology finals in October.
With Groote Schuur Hospital a number of specialised clinics have been evolved. Some involve collaboration with other specialties such as Oncology and Urogynaecology. Other clinics run entirely by the Division of Urology are stricture clinic, stone clinic, reconstructive clinic and the haematuria clinic.

Divisional Statistics

Permanent and Long-term Contract Staff

Principal Lecturer	1
Senior Lecturers	2
Administrative	1
Sessional Senior Lecturers	4
Total	8

Students

Masters	5
Masters MSc	1
Undergraduate (5^th years)	170
Total	176

Research Fields and Staff
Professor A R Pontin

Principal Lecturer; Urological oncology; female incontinence; renal infection in diabetics

Dr R D Barnes

Senior Lecturer; Urological oncology; metabolic aspects of renal calculus disease

Dr A van der Merwe

Senior Specialist – Development of a urinary flow meter, laparoscopic urology; Haematuria – a one-stop service protocol

Dr J Lazarus

Acting Specialist – Red Cross War Memorial Children’s Hospital; Hypospadias at Red Cross, 600 cases in 10 years; Buried Penis: A new simplified surgical technique; Virtual UroRadiology Library; Urodynamics at Red Cross: audit at the first 100 cases; Bladder Exstrophy: 40 cases over 40 years.

Dr P de Bruin

Study of Adenocarcinoma of Bladder

Dr S Sinha

Changes in children with Neuropathic Bladders

Dr P Nakangombe

Survival of Patients with advanced Carcinoma of Prostate (part of MSc Thesis)

Contact Details

Postal Address: Division of Urology, UCT Medical School, Area E26, New Groote Schuur Hospital, Observatory 7925

Telephone: [phone]

Fax: [phone]

E-mail: [e-mail]

Department of Surgery
Research Output
ARTICLES IN PEER-REVIEWED JOURNALS
Abdul-Rasool, S., Kidson, S.H., Panieri, E., Dent, D., Pillay, K. and Hanekom, G. 2006. An evaluation of molecular markers for improved detection of breast cancer metastases in sentinel nodes. Journal of Clinical Pathology, 59: 289-297.
Apostolou, C., Krige, J.E. and Bornman, P.C. 2006. Pancreatic pseudocysts. South African Journal of Surgery, 44(2): 70-77.
Apostolou, C., Krige, J.E. and Bornman, P.C. 2006. Pancreatic pseudocysts. South African Journal of Surgery, 44(2): 148-155.
Cauchi, J.A., Oliff, S., Baumann, U., Mirza, D., Kelly, D.A., Hewitson, J.P., Rode, H., McCulloch, M., Spearman, W. and Millar, A.J.W. 2006. The Budd-Chiari syndrome in children: The spectrum of management. Journal of Pediatric Surgery, 41: 1919-1923.
Dandara, C., Li, D.P., Walther, G. and Parker, M.I. 2006. Gene-environment interaction: The role of SULT1A1 and CYP3A5 polymorphisms as risk modifiers for squamous cell carcinoma of the oesophagus. Carcinogenesis, 24(4): 791-797.
Davidson, A., Desai, F., Stannard, C.E., Ivey, A.T., Solomons, R. and Sinclair-Smith, C.C. 2006. Intraocular rhabdomyosarcoma in the sibling of a patient with a cerebellar medulloepithelioma. Journal of Pediatric Hematology Oncology, 28: 476-478.
Donald, K.A., Grotte, R.H. and Wilmshurst, J. 2006. Gillespie Syndrome: Two further cases. Journal of Child Neurology, 21(4): 1-3.
Du Toit, G., Prescott, R.A., Lawrence, P.R., Johar, A., Brown, G., Weinberg, E.G., Motala, C. and Potter, P.C. 2006. Autoantibodies to the high-affinity IgE receptor in children with chronic urticaria. Annals of Allergy Asthma and Immunology, 96(February): 1-4.
Dunn, R.N. and Ombachi, R. 2006. Transarticular screw fixation of the atlanto-axial sine: a safe and effective option. South African Orthopaedic Journal, 5(3): 34-41.
Everaets, F., Gillissen, M., Torrianni, M., Zilla, P., Human, P.A., Hendriks, M. and Feijen, J. 2006. Reduction of calcification of carbodiimide-processed heart valve tissue by prior blocking of amine groups with monoaldehydes. Journal of Heart Value Disease, 15: 269-277.
Fagan, J. 2006. Cost of tracheoesophageal prostheses in developing countries. Facing the problem from an internal perspective. Acta Oto-Laryngologica, 126(1): 4-9.
Fagan, J. and Isaacs, S. 2006. Adult tonsillectomy - are long waiting lists putting patients at risk? South African Journal of Surgery, 2(44): 66-8.
Figaji, A.A., Fieggen, A.G., Argent, A.C. and Peter, J.C. 2006. Surgical treatment for 'brain compartment syndrome' in children with severe head injury. South African Medical Journal, 96(9): 969-975.
Figaji, A.A., Fieggen, A.G., Schoeman, J.F. and Peter, J.C. 2006. Endoscopic third ventriculostomy in post-tubercular meningitic hydrocephalus. Minimally Invasive Neurosurgery, 49: 60-61.
Figaji, A.A., Fieggen, A.G., Semple, P.L. and Peter, J.C. 2006. Intracranial endoscopy. South African Medical Journal, 96(1): 32-37.
Freedman, P.N., Goldberg, P.A., Fataar, A.B. and Mann, M.D. 2006. A comparison of methods of assessment of scintigraphic colon transit. Journal of Nuclear Medicine Technology, 34(2): 76-81.
Goldberg, P.A., Hameed, M., Hall, P., Algar, U., Van Wijk, R. and Ramesar, R. 2005. Immunohistochemistry detects mismatch repair gene defects in colorectal cancer. Colorectal Diseases, 8(5): 411-7.
Gottschalk, S.B., Wood, D., De Vries, S., Wallis, L.A. and Bruijns, S. 2006. The cape triage score: a new triage system South Africa. Proposal from the cape triage group. Emergency Medicine Journal, 23: 149-153.
Habte, H., Mall, A.S., De Beer, C., Lotz, Z. and Kahn, D. 2006. The role of crude human saliva and purified salivary MUC5B and MUC7 mucins in the inhibition of human immunodeficiency virus type I in an inhibition assay. Virology Journal, 3(99). [Online]. http://www.virologyj.com/content/3/1/99.
Ing, R., Fischer, S., Shipton, S., Gray, R., Thomas, J.M. and Hewitson, J.P. 2006. Regional cerebral oxygenation monitoring - intraoperative management in a patient with severe left ventricular dysfunction. South African Medical Journal, 96(12): 1266-68.
Jonas, N.E., Fagan, J., Thandar, M., Pitcher, R. and Fagan, J.J. 2006. Primary neuroblastoma: A rare cause of a retropharyngeal mass in a neonate. Journal of Laryngology and Otology, 1(E15): 1-3.
Kahn, D., Pillay, S., Veller, M.G., Panieri, E. and Westcott, M.J.R. 2006. General Surgery in crisis - the critical shortage. South African Journal of Surgery, 44(3): 88-94.
Kahn, D., Pillay, S., Veller, M.G., Panieri, E. and Westcott, M.J.R. 2006. General Surgery in crisis - comparatively low levels of remuneration. South African Journal of Surgery, 44(3): 96-107.
Kahn, D., Pillay, S., Veller, M.G., Panieri, E. and Westcott, M.J.R. 2006. General surgery in crisis - factors that impact on a career in general surgery. South African Journal of Surgery, 44(3): 108-112.
Karpelowsky, J.S., Wieselthaler, N. and Rode, H. 2006. Primary paraesophageal hernia in children. Journal of Pediatric Surgery, 41(9): 1588-1593.
Krige, J.E. and Beningfield, S.J. 2006. Delayed presentation of haemobilia after penetrating liver injury (Letter to the editor). HPB Surgery, 8(3): 235.
Krige, J.E. and Beningfield, S.J. 2006. Liver resection for complicated hepatolithiasis (Letter to the editor). Archives of Surgery, 141: 713-714.
Krige, J.E. and Beningfield, S.J. 2006. Subcutaneous tunnel and hepatocholangioplasty after resection for intrahepatic stones (Letter to the editor). Hepatobilary and pancreatic diseases international, 5(3): 474-475.
Krige, J.E. and Beningfield, S.J. 2006. The new DEAL - a novel technique using a double-entry access loop to facilitate bilateral intrahepatic biliary access for complex intrahepatic stones. South African Journal of Surgery, 44(2): 56-58.
Krige, J.E., Kotze, U.K., Bornman, P.C., Shaw, J.M. and Klipin, M. 2006. Variceal recurrence, rebleeding and survival after endoscopic injection with sclerotherapy in 287 alcoholic cirrhotic patients with bleeding esophageal varices. Annals of Surgery, 244: 764-770.
Landau, A., Van As, A.B., Numanoglu, A., Millar, A.J.W. and Rode, H. 2006. Liver injuries in children: The role of selective non-operative management. Injury –International Journal of the Care of the Injured, 37: 66-71.
Lang, C.I. and Carelse, M.I. 2006. Order hardening in platinum 14at.% copper. Scripta Materialia, 54: 1311-1315.
Lawrenson, J., Kalis, N.N., Pribut, H.S., Hewitson, J.P., Stirling, J., Shipton, S. and De Decker, R. 2006. Why are some South African children with Down syndrom not being offered cardiac surgery? South African Medical Journal, 96(9): 914-9.
Le Roux, J.C. and Dunn, R.N. 2005. Gunshot injuries of the spine. South African Journal of Surgery, 43(4): 164-168.
Lecour, S., Owira, P.M.O. and Opie, L.H. 2006. Ceramide-induced preconditioning involves reactive oxygen species. Life Sciences, 78: 1702-1706.
Lichtenberg, W., Walther, G., Linegar, A. and De Groot, K.M. 2006. Pulmonary aspergillomata: An assessment of surgical outcome with a view to clinical decision-making. South African Respiratory Journal, 12(3): 102-108.
Lubbe, D., Gardiner, I. and Fagan, J. 2005. An unusual orbital foreign body resulting in the orbital apex syndrome: Report of a case. Archives of Otolaryngology – Head and Neck Surgery, 6(131): 526-8.
Maree, M., Dix-Peek, S.I. and Hoffman, E.B. 2006. The treatment and prevention of pathological fractures due to rickets in children with quadriplegic cerebral palsy and mental retardation. South African Orthopaedic Journal, May(2): 56-60.
McCulloch, M., Gajjar, P., Spearman, W., Burger, H., Sinclair, P., Savage, L., Morrison, C., Davies, C., Ruysch van Dugteren, G.P.A., Maytham, D., Wiggelinkhuizen, J., Pascoe, M.D., McCurdie, F.J., Pontin, A., Muller, E., Numanoglu, A., Millar, A.J.W., Rode, H. and Khan, D. 2006. Overview of a paediatric renal transplant programme. South African Medical Journal, 96(9): 955-959.
Navsaria, P.H. and Nicol, A. 2006. Thoracoscopic pericardial window for penetrating cardiac trauma. South African Journal of Surgery, 44(1): 18-21.
Navsaria, P.H., Nicol, A., Ball, C.G., Hameed, S.M. and Kirkpatrick, A.W. 2006. Successful damage control of complex vascular and urological gunshot injuries. Canadian Journal of Surgery, 49(6): 437-438.
Navsaria, P.H., Thoma, M. and Nicol, A. 2006. Foley catheter balloon tamponade for life-threatening hemorrhage in penetrating neck trauma. World Journal of Surgery, 30(7): 1265-1268.
Oosthuysen, A., Zilla, P., Human, P.A., Schmidt, A.P. and Bezuidenhout, D. 2006. Bioprosthetic tissue preservation by filling with a poly(acrylamide) hydrogel. Biomaterials, 27: 2123-2130.
Rippstein, P., Black, M., Boivin, M., Veinot, J.P., Ma, X., Chen, Y.X., Human, P.A., Zilla, P. and O'Brien, E.R. 2006. Comparison of processing and sectioning methodlogies for arteries containing metallic stents. Journal of Histochemistry and Cytochemistry, 54(6): 673-681.
Rode, H., Fieggen, A.G., Brown, R.A., Cywes, S., Davies, M.R.Q., Hewitson, J.P., Hoffman, E.B., Jee, L., Lawrenson, J. and Mann, M.D. 2006. Four decades of conjoined twins at Red Cross Children's Hospital - lessons learned. South African Medical Journal, 96(9): 634-940.
Rode, H., Fieggen, A.G., Brown, R.A., Cywes, S., Davies, M.R.Q., Hewitson, J.P., Hoffman, E.B., Jee, L., Lawrenson, J., Mann, M.D., Matthews, L., Millar, A.J.W., Numanoglu, A., Peter, J.C., Thomas, J.M. and Wainwright, H.C. 2006. Four decades of conjoined twins at Red Cross Children's Hospital - lessons learned. South African Medical Journal, 96(9): 931-940.
Roussot, M.A., Lawrenson, J., Hewitson, J.P., Smart, R.D. and De Decker, H. 2006. Is cardiac surgery warranted in children with Down syndrome? A case-controlled review. South African Medical Journal, 96(9): 924-30.
Scherman, F. and Walther, G. 2006. Bilateral pulmonary hydatid disease - surgical approaches: A case report and brief literature review. South African Respiratory Journal, 12(3): 116-117.
Semple, P.L., De Villiers, J.C., Bowen, R.M., Beatriz, M., Edward, R. and Laws, J.R. 2006. Pituitry apoplexy: Do histological features influence the clincal presentation and outcome? Journal of Neurosurgery, 104(June): 931-937.
Semple, P.L., Fieggen, A.G., Parkes, J. and Levitt, N.S. 2006. Giant prolactinomas in adolescence: An uncommon cause of blindness. Child's Nervous System, 23(2): 213-217.
Shaw, J.M., Bornman, P.C. and Krige, J.E. 2006. Hydatid disease of the liver. South African Journal of Surgery, 44: 70-77.
Siboto, G., Von Bormann, R. and Alexander, R.L. 2006. Diagnosis of simple posterior hip dislocation: Obturator oblique X-ray views pre-and post reduction obviate the need for computerised tomography scan (CT Scan). South African Orthopaedic Journal, 5(3): 64-70.
Spearman, W., McCulloch, M., Millar, A.J.W., Burger, H., Numanoglu, A., Goddard, E., Gajjar, P., Davies, C., Muller, E., McCurdie, F.J., Kemm, D., Cywes, S., Rode, H. and Kahn, D. 2006. Liver transplantation at Red Cross War Memorial Children's Hospital. South African Medical Journal, 96(9): 960-963.
Talving, P., Nicol, A. and Navsaria, P.H. 2006. Civilian duodenal gunshot injuries: surgical management made simpler. World Journal of Surgery, 30(4): 488-494.
Timm, J., Kurepina, N., Kreiswirth, B.N., Post, F.A., Walther, G., Wainwright, H.C., Bekker, L.G., Kaplan, G. and McKinney, J.D. 2006. A multidrug-resistant, acr1-deficient clinical isolate of Mycobacerium tuberculosis is unimpaired for replication in macrophages. Journal of Infectious Diseases, 193: 1703-10.
Van der Merwe, S.W., Conradia, M.M., Bond, R., Olivier, B.J., Fritz, E., Nieuwoudt, M., Delport, R., Slavik, T., Engelbrecht, G.H.C., Kahn, D., Shephard, E.G., Kotze, M., De villieres, N. and Hough, S. 2006. Effect of rapamycin on hepatic osteodystrophy in rats with portasystemic shunting. World Journal of Gastroenterology, 12(28): 4504-4510.
Von Bormann, R. and Dunn, R.N. 2005. Atlanto-axial tuberculosis: A report of 5 cases. South African Orthopaedic Journal, May(5): 34-39.
Wallis, L.A. 2006. Comparison of resting heart and respiratory rates in UK and South African. Archives of Disease in Childhood, 91: 330-333.
Wallis, L.A. 2006. The Cape Triage Score. Emergency Medicine Journal, 23: 740.
Wallis, L.A. and Carley, S. 2006. Comparison of paediatric mass casualty primary triage tools. Emergency Medicine Journal, 23: 475-478.
Wallis, L.A. and Carley, S. 2006. Validation of the Paediatric Triage Tape. Emergency Medicine Journal, 23: 47-50.
Wallis, L.A. and Maconochie, I. 2005. Reference ranges for respiration and heart rate in healthy children aged 4 to 16 years. Archives of Disease in Childhood, 90: 1117-1121.
Wallis, L.A. and Maconochie, I. 2006. Age related reference ranges of respiratory rate and heart rate for children in South Africa. Archives of Disease in Childhood, 91: 330-333.
Wallis, L.A., Carley, S. and Hodgetts, C.T. 2006. A procedure based alternative to the injury severity score for major incident triage of children: results of a Delphi consensus process. Emergency Medicine Journal, 23: 291-295.
Wallis, L.A., Gottschalk, S.B., Wood, D., Bruijns, S. and De Vries, S. 2006. A triage system for the Cape Town area: proposal from the Cape Triage Group. South African Medical Journal, 96: 30-32.
Wallis, L.A., Gottschalk, S.B., Wood, D., Bruijns, S., De Vries, S. and Balfour, C.H. 2006. The Cape Triage Score - a triage system for South Africa. South African Medical Journal, 96(1): 53-56.
Walters, J. 2006. Isolated Posterior Cruciate Ligament Injury: Does surgery improve the outcome? South African Journal of Surgery, 5(1): 8-14.
Walters, J. 2006. Ruptures of the quadriceps and patellar tendon in adults. South African Orthopaedic Journal, 5(2): 44-54.
Zilla, P., Bezuidenhout, D. and Human, P.A. 2005. Carbodiimide treatment dramatically potentiates the anti-calcific effect of alpha-amino oleic acid on glutaraldehyde treated tissue. Annals of Thoracic Surgery, 79: 905-910.

CHAPTERS IN BOOKS
Dent, D. and James, M.F.M. 2005. Perioperative care of patients with endocrine neoplasms. In A.D. Shaw, B.J. Riedel, A.W. Burton and T.W. Feeley (eds), Acute care of the cancer patient: 407-31. USA: Taylor and Francis Group.
Krige, J.E., Beningfield, S.J. and Bornman, P.C. 2006. Liver and portal circulation. In K.G. Burnanad, A.E. Young, J. Rowlands, J. Scholefield and J. Lucas (eds), New Aird's companion in surgical studies: 683-707. London: Churchill Livingstone.
Krige, J.E., Beningfield, S.J. and Bornman, P.C. 2006. Management strategies in pancreatic trauma. In C.D. Johson and I. Taylor (eds), Recent advances in surgery: 95-117. London: Royal Society of Medicine Press Ltd.

PUBLISHED CONFERENCE ABSTRACTS
Navsaria, P.H., Ibirogba, S.B. and Nicol, A. 2006. Re-evaluation of diagnostic procedures for penetrating transthoracic injuries. SAMJ 96 (6) : 548.
Navsaria, P.H., Talving, P. and Nicol, A. 2006. Operative management of duodenal gunshot wounds. SAMJ 96 (6) : 548.
Navsaria, P.H., Thoma, M. and Nicol, A. 2006. Foley-Catheter balloon tamponade for life threatening haemorrhage in penetrating neck trauma. SAMJ 96 (6) : 544.
Shaw, J.M., Bornman, P.C., Callanan, M.D. and Metz, M.D. 2006. Longterm (6 year) outcome of Laparascopic Nissen and Toupet Fundoplication. Gasteroenterol 130 (2): A-878.
Talving, P., Nicol, A. and Navsaria, P.H. 2006. Duodenal gunshot wounds: Primary repair revalidated. Internation Jopurnal of Disaster Medicine 4 (1-2) : 4.

UNIVERSITY PUBLICATIONS AND WORKS OF A POPULAR NATURE
Semple, P.L., Ross, I.L., Duffield, M., Levitt, N.S. and Isiavwe, A.R. 2006. An unusual case of acromegaly. CME, 24(9): 533-534.

Consultancy and other activities based on expertise developed in research
Dr. Colin Cook: Dr. Colin Cook acts as a consultant to the International Agency for the Prevention of Blindness, the Bureau for the Prevention of Blindness, the Department of Health's National Blindness Prevention Programme Committee and to Christoffel Blindenmission. He oversees the CBM Blindness Prevention programmes in South Africa, Zimbabwe, Mocambique, Kenya, Madagascar, Swaziland and Zambia.
Dr. Rhian Grotte: Dr. Rhian Grotte acts as a consultant on congenital cataract surgery to the Helen Keller Foundation of New York.
Dr. Karin Lecuona: Dr. Karin Lecuona acts as a consultant to the Western Cape Prevention of Blindness Committee. She is an invited member of the Executive Committee of the Ophthalmological Society of South Africa, and serves on the Committee of the College of Ophthalmology of South Africa.
Professor Anthony Murray: Professor Anthony Murray is Co-Chairman Sub-Saharan Africa Region, International Agency for the Prevention of Blindness; Member International Affairs Committee, American Association of Pediatric Ophthalmology and Strabismus; Board Member of the Pan Arab African Council of Ophthalmology. He serves as a member of the Department of Health's National Blindness Prevention Programme Committee; the Committee of the Bureau for the Prevention of Blindness, and on the International Advisory Board of the Journal "Survey of Ophthalmology".