Electronic poster

Thursday 13:30-15:30 Computer 90

13:30 4546. Breast BOLD Correlates to Optical Breast Imaging During Respiratory Stimulus

Colin Morehouse Carpenter^1,2, Rebecca Rakow-Penner³, Shudong Jiang², Brian William Pogue², Keith David Paulsen², Gary H. Glover<sup>3

1</sup>Radiation Oncology, Stanford University School of Medicine, Stanford, CA, United States; ²Thayer School of Engineering at Dartmouth, Hanover, NH, United States; ³Radiology, Stanford University School of Medicine, Stanford, CA, United States

BOLD response in the breast was measured concurrently with MR-guided diffuse optical tomography (MRg-DOT) in 11 healthy volunteers during inspired gas changes. This approach utilized optical imaging to quantitatively identify the independent effects of oxy- and deoxyhemoglobin. A key factor in this study was characterization of the background physiological noise variations in individual subjects, which was measured via optical imaging during air breathing. The results from this work indicate that BOLD and optically-determined deoxyhemoglobin signals correlate significantly in the breast during an oxygen/carbogen respiratory stimulus, as long as only subjects that exhibit a significant response are included.

14:00 4547. MR Breast Density Measurement: Comparison of Two Anatomic Landmarks for Breast Segmentation

Jeon-Hor Chen^1,2, Shih-Ting Chen², Cheng-Ju Lin², Daniel Chang¹, Po-Pang Tsai², Ke Nie¹, Orhan Nalcioglu¹, M-Y Lydia Su<sup>1

1</sup>Center for Functional Onco-Imaging, UC Irvine, Irvine, CA, United States; ²China Medical University Hospital, Taichung, Taiwan

Although breast density measurement showed high correlation using both anatomic landmarks, there was still an average of 20% difference for FV measurement. A significant number of women had the problem of being cut off of their fibroglandular tissue when the pectoris major muscle was used as the landmark. From our study, it was concluded that in women with dense breast such as the subjects included in this study, both anatomic landmarks, especially the one anterior to the pectoris major muscle, will have the problem of cut-off of the fibroglandular tissue, resulting in the acquired fibroglandular tissue underestimated.

14:30 4548. Comparison of Breast Density Measured on Fat-Suppressed Versus Non-Fat-Suppressed MRI

Daniel Han-en Chang¹, Jeon-Hor Chen^1,2, Shadfar Bahri¹, Hon J. Yu¹, Ke Nie¹, Orhan Nalcioglu¹, Min-Ying Lydia Su<sup>1

1</sup>Tu & Yuen Center for Functional Onco-Imaging, University of California, Irvine, CA, United States; ²Department of Radiology, China Medical University Hospital, Taichung, Taiwan

Mammographic density is known to be strongly associated with the risk of breast cancer development, but using mammography to characterize breast density does not provide true volumetric information. MRI-based methods on the other hand provide promising alternatives, but may be affected by technical factors such as the choice of pulse sequences. We imaged breasts with two commonly used pulse sequences, fat-suppression and non-fat-suppression, and calculated their densities with an MRI-based method developed previously by our lab. We found that their densities are highly correlated and that fat-saturated images tend to have stronger relative tissue contrast.

15:00 4549. Correction of Skin Volume in the Breast Density Measured by MRI

Ke Nie¹, Daniel Chang¹, Jeon-Hor Chen^1,2, Tzh-Ching Shih^1,2, Chieh-Chih Hsu², Orhan Nalcioglu¹, Min-Ying Lydia Su<sup>1

1</sup>Tu & Yuen Center for Functional Onco-Imaging, University of California, Irvine, Irvine, CA, United States; ²Department of Radiology, China Medical University, Taichung, Taiwan

There is a great interest to correlate between the density measured on MRI and mammogram, so the established role for mammographic density may be extended to MRI-based density. One problem specific to volumetric MRI analysis is the inclusion of skin as the dense tissue. In contrast this effect could be ignored on projection mammogram. In this study, we investigated the correlation between the volume of the skin and the breast on 3D MRI. We further provided two correction models aiming to provide an estimation of the skin volume and its effect on MRI based density measurement.

Breast MR

Hall B Monday 14:00-16:00 Computer 91

14:00 4550. Contrast-Enhanced 1.5-T MR Imaging of the Breast: Association Between Asymmetric Increase of Whole Breast Vascularity and Ipsilateral Cancer on a Series of 384 Studies

Luca Alessandro Carbonaro¹, Nicola Verardi, Henrida Kule, Giovanni Di Leo, Francesco Sardanelli<sup>1

1</sup>Unit of Radiology, Università degli Studi di Milano, IRCCS Policlinico San Donato, San Donato Milanese, Milan, Italy

We estimated the value of the breast vascular map asymmetry (BVMA) as a marker of ipsilateral tumors. Three-hundred-eighty-four patients underwent a dynamic study. We looked for BVMA. Pathologic examination or follow-up served as a reference standard. Pathology revealed 173 malignant lesions and 211 benign lesions. BVMA showed high diagnostic performance. Sensitivity was 76% for invasive cancers and 39% for in-situ cancers (P<0.001). Breast vascular map asymmetry was associated with ipsilateral cancer in 76% of invasive tumors, only in 39% of DCIS. For ¡Ý20-mm tumors, a 90% association was found.

14:30 4551. Feasibility of the Usage of the Internal Mammary Artery as an Artery Input Function in Pharmacokinetic Analysis Using the Contrast Enhanced Dynamic MR Study in Breast Tumor

In Chan Song¹, Nariya Cho¹, Yong Sik Bang¹, Woo Kyung Moon<sup>1

1</sup>Department of Radiology, Seoul National University Hospital, Seoul, Chongno-gu, Daehangno 101, Korea, Republic of

We evaluated a feasibility of the usage of internal mammary artery near chest wall as an artery input function in contrast enhanced dynamic MR study to obtain the permeability map in breast tumor. Ktrans and Kep were successfully measured using the internal mammary artery as an artery input function based on the Tofts model in all patients. In breast tumor, the good performance in fitting procedure and the acquired two parameters showed that the internal mammary artery may be used as an artery input function in pharmacokinetic analysis.

15:00 4552. Breast MRI Using a Balanced Steady-State Free Precession Imaging with a Two-Point Dixon Fat-Water Reconstruction Algorithm: Preliminary Experience and Comparison with 2D FSE

Christine Lee¹, Manoj Saranathan², Gina Hesley¹, Robert Maxwell¹, Kathy Brandt<sup>1

1</sup>Mayo Clinic, Rochester, MN, United States; ²Applied Science Lab, GE Healthcare, Rochester, MN, United States

Clinical evaluation of an ultrafast T2-like acquisition with near isotropic resolution in breast MRI is compared to more conventional 2D Fast Spin Echo.

15:30 4553. Breast MRI Using TWIST: Doubling the Spatial Resolution “for Free”

Rolf Janka¹, Evelyn Wenkel¹, Christian Geppert², Berthold Kiefer², Michael Uder<sup>1

1</sup>Radiology, Universitity of Erlangen, Erlangen, Bavaria, Germany; ²Siemens Medical Solutions

The TWIST sequence divides k-space in two radial regions and samples it using a pseudo-stochastic trajectory at adjustable density. While the central region is sampled at the full temporal resolution, the periphery is sampled with reduced density. Its main field of application is an increase of temporal resolution in MR-angiography. But it can also be used to increase spatial resolution in the dynamic sequence of breast MRI. We tested the new sequence in 61 women and think it is a reliable and powerful tool in breast imaging which fulfil the requirements of both high temporal and spatial resolution.

Tuesday 13:30-15:30 Computer 91

13:30 4554. Using T2-Weighted MRI in the Automated Analysis of Breast Cancer Lesions

Neha Bhooshan¹, Maryellen Giger¹, Li Lan¹, Angelica Marquez², Hui Li¹, Gillian Newstead<sup>1

1</sup>University of Chicago, Chicago, IL, United States; ²Loyola University, Chicago, IL, United States

This study’s purpose was to investigate the automated analysis of T2-weighted MR images in distinguishing malignant and benign breast lesions. Using 86 benign and 110 malignant lesions, our CADx scheme automatically performed lesion segmentation, feature extraction, and classification. T2 morphological features yielded an AUC of 0.78± 0.03 while T1 kinetic and morphological features achieved an AUC of 0.83± 0.03. When considering all features, two T2 features, three T1 features and one geometric feature were selected, giving an AUC of 0.85± 0.03. T2 MRI has the potential to improve the performance of CADx in distinguishing malignant and benign breast lesions.

14:00 4555. Incidental Enhancing Lesions Found on Preoperative Breast MRI: Management and Role of Second Look Ultrasound

Maria Laura Luciani¹, Federica Pediconi, Valeria Dominelli, Marianna Telesca, Valeria Casali, Federica Vasselli, Carlo Catalano, Roberto Passariello

¹of Radiological Sciences, "La Sapienza" University of Rome, Rome, Italy

We evaluated the role of second look US for the study of occasional lesions detected on preoperative breast MRI and we proved it can be an helpful way to localize and study lesions depicted only on preoperative breast MRI.

14:30 4556. Correlation of Prognostic Parameters and MR Perfusion Parameters in Dynamic Contrast Enhanced MRI (DCE-MRI) in Patients with Breast Cancers

Nariya Cho¹, In Chan Song¹, Yong Sik Bang¹, Woo Kyung Moon<sup>1

1</sup>Department of Radiology, Seoul National University Hospital, Seoul, Korea, Republic of

Transfer constant obtained from DCE-MRI are well correlated with tumor size and histologic grade of breast cancer, which shows its potential as a noninvasive prognostic parameter in the breast cancer patient.

15:00 4557. The Evaluation of the Disease Extent in Patient with Ductal Carcinoma in Situ: Comparison of Mammography, Sonography, and MRI

Kyoung Eun Lee¹, Hak Hee Kim¹, Jeong-Hee Sohn¹, Hee Jung Shin¹, Gyungyub Gong², Se Hyun Ahn³, Hyeon Sook Kim⁴, Eun Suk Cha<sup>4

1</sup>Radiology, Asan Medical Center, Seoul, Korea, Republic of; ²Pathology, Asan Medical Center, Seoul, Korea, Republic of; ³General Surgery, Asan Medical Center, Seoul, Korea, Republic of; ⁴Radiology, The Catholic University of Korea, Seoul, Korea, Republic of

We think that in patient with DCIS, complemented MRI may be best establish the presence and extent of disease.

Wednesday 13:30-15:30 Computer 91

13:30 4558. Multifunctional MRI to Detect and Localize Multifocal and Multicentric Breast Cancer

Elizabeth O'Flynn¹, Anna Kirby², Maria Schmidt¹, Ashutosh Nerurkar³, Veronica A. Morgan¹, Erica Scurr¹, John Yarnold², Nandita M. deSouza<sup>1

1</sup>Cancer Research UK and EPSRC Cancer Imaging Centre, Institute of Cancer Research & Royal Marsden NHS Foundation Trust, Sutton, Surrey, United Kingdom; ²Clinical Academic Radiotherapy, Institute of Cancer Research & Royal Marsden NHS Foundation Trust, Sutton, Surrey, United Kingdom; ³Histopathology, Institute of Cancer Research & Royal Marsden NHS Foundation Trust, Sutton, Surrey, United Kingdom

This pilot study demonstrates the accuracy of dynamic contrast-enhanced (DCE)-MRI and diffusion-weighted (DW)-MRI in detecting and localising multifocal and multicentric disease in patients with breast cancer by correlating imaging with histopathology findings at mastectomy. DCE-MRI alone was most accurate in detecting satellite lesions (sensitivity of 89%), DW-MRI was least accurate (sensitivity 55%). Satellite lesions were found up to 22 mm from the edge of the index lesion. Accurate identification of satellite lesions with multifunctional MRI offers potential for monitoring the effects of local therapies on multifocal and multicentric disease, and in defining the target volume for partial breast irradiation.

14:00 4559. Magnetic Resonance Imaging for Axillary Staging in Breast Cancer Patients Receiving Neoadjuvant Chemotherapy: Comparison with Ultrasonography and Positron Emission Tomography

Sun Mi Kim¹, Chae Yeon Lyou¹, Mijung Jang<sup>1

1</sup>Seoul National University Bundang Hospital, Seongnam-Si, Gyunggido, Korea, Republic of

The presence of axillary lymph node(LN) metastases in breast cancer is an important factor in assessing prognosis and determines management. Although surgical biopsy remains the gold standard for the diagnosis of axillary LN metastasis but standard for surgical biopsy in monitoring for chemotherapy response does not established yet. Comprehensive and sequential staging of axilla using noninvasive diagnostic modalities has been approached and which would represent an importance advance in the management of breast cancer patients. This presentation evaluate the accuracy of comprehensive pre- and post-neoadjuvant chemotheraphy axillary staging via MRI, ultrasound imaging and positron emission tomography.

14:30 4560. MRI Findings of Triple Negative Breast Cancer: A Comparison with Non Triple Negative Breast Cancer

Jae Jeong Choi¹, Sung Hun Kim², Eun Suk Cha³, Hyun Suk Kim⁴, Jae Young Byun², Bong Joo Kang², Ji Hye Lee<sup>2

1</sup>Radiology, Seoul St. Mary's Hospital, Catholic University of Korea , Seoul, Korea, Republic of; ²Radiology, Seoul St. Mary's Hospital, Catholic University of Korea, Seoul, Korea, Republic of; ³Radiology, St. Vincent's Hospital, Catholic University of Korea, Seoul, Korea, Republic of; ⁴Radiology, St. Paul's Hospital, Catholic University of Korea, Seoul, Korea, Republic of

We would like to submit our report titled ¡°MRI Findings of Triple Negative Breast Cancer: A Comparison with Non Triple Negative Breast Cancer¡¯¡¯. Triple negative breast cancer is a subtype with aggressive clinical behavior which currently lacks effective targeted therapies. MRI characteristics of triple negative breast cancer could assist pretreatment planning and prognosis assessment. We evaluated MRI and clinicopathologic features of triple negative breast cancer, and compared them with those of non triple negative breast cancer.

15:00 4561. Multiparametric MR Measurement of Menstrual Variation in the Breast

Sungheon Kim¹, Linda Moy¹, Malcolm C. Pike², Anne Zeleniuch-Jacquotte³, Tess Clendenen<sup>4

1</sup>Center for Biomedical Imaging, Radiology, NYU School of Medicine, New York, NY, United States; ²Preventive Medicine, USC Keck School of Medicine, Los Angeles, CA, United States; ³Environmental Medicine, NYU School of Medicine, New York, NY, United States; ⁴Epidemiology, NYU School of Medicine, New York, NY, United States

The purpose of this study was to develop a multiparametric MRI method to investigate magnitude and timing of various breast changes during the menstrual cycle. Five healthy premenopausal women were scanned once a week for four weeks. T2, ADC, and magnetization transfer rate were measured. T2 gradually increased throughout the cycle and was 5% higher in the menstrual phase than the follicular phase. In contrast, the median ADC was highest in the luteal phase (15% greater than the follicular phase) and began to decline during menses. The MTR was about 4% lower in the menstrual phase than the follicular phase.

Fetal & Female Pelvis

Hall B Thursday 13:30-15:30 Computer 91

13:30 4562. Time-Resolved MR Angiography in the Detection of Ovarian Venous Reflux

Dal Mo Yang¹, Dong Ho Lee², Dong Wook Sung², Geon-Ho Jahng, Chang Woo Ryu

¹Radiology, East-West Neo Medical Center, Kyung Hee University, Seoul, Korea, Republic of; ²Radiology, Kyung Hee University Hospital

The purpose of this study was to compare the diagnostic accuracy of time-resolved MR angiography with that of conventional angiography for detection of ovarian venous reflux, which aid for a diagnosis of pelvic venous congestion. Retrospective analysis was performed with 19 consecutive patients who underwent time-resolved MR angiography and conventional angiography. There was no significant difference between time-resolved MR angiography and conventional angiography for detection of ovarian venous reflux (P > 0.05). The sensitivity, specificity, and diagnostic accuracy of time-resolved MR angiography were found to be 93.5%, 66.7%, and 89.5%, respectively. Time-resolved MR angiography is helpful for diagnosis of pelvic venous congestion.

14:00 4563. Magnetic Resonance Imaging and Ultrasonography in Diagnosis of Pelvic Vein Thrombosis During Pregnancy

Michael R. Torkzad¹, Katarina Bremme², Margareta Hellgren³, Maria J. Eriksson⁴, Anna Hagman⁵, Trine Jörgensen², Kent Lund⁴, Gunnel Sandgren⁶, Lennart Blomqvist⁷, Peter Kälebo<sup>8

1</sup>Radiology Department, Uppsala University Hospital, Stockholm, Sweden; ²Karolinska Institutet, Woman and Child Health, Stockholm, Sweden; ³The Sahlgrenska Academy, University of Gothenburg, Institute for the Health of Women and Children, Gothenburg, Sweden; ⁴Karolinska Institutet, Department of Clinical Physiology, Stockholm, Sweden; ⁵The Sahlgrenska Academy, Institute for the Health of Women and Children, Gothenburg, Sweden; ⁶Sahlgrenska University Hospital/Östra, Department of Clinical Physiology, Gothenburg, Sweden; ⁷Department of Diagnostic Radiology, Karolinska University Hospital Solna, Department of Diagnostic Radiology, Stockholm, Sweden; ⁸Sahlgrenska University Hospital/Östra, Department of Radiology, Gothenburg, Sweden

Purpose: The agreement between ultrasonography and magnetic resonance imaging (MRI) in diagnosing the extent of pelvic deep vein thrombosis (DVT) during pregnancy was measured. Materials and methods Pelvic veins of 27 pregnant women with DVT were examined with ultrasound and MRI. Results: Three cases (11.5%) of DVT in the pelvic veins were shown only on MRI. MRI was able to detect highr thrombus extension in 65% of cases. Proportion of agreement (ê) between ultrasound and MRI for DVT in individual veins was 0.33 (95% CI 0.27-0.40, i.e. fair agreement). Conclusion: MRI could be essential in diagnosis of pelvic DVT during pregnancy.

14:30 4564. Assessment of Placental Blood Flow Using a Navigator Echo Respiratory Gated Parallel Imaging Technique at 1.5 T

Loredana Sorina Truica¹, Ian Cameron, ^1,2, Leonard I. Avruch², Andre Gruslin<sup>2

1</sup>Carleton University, Ottawa, ON, Canada; ²The Ottawa Hospital, Ottawa, ON, Canada

IVIM measurements of normal placenta at 1.5 T using a respiratory triggered DW_SS_EPI sequence are reported. Improvements in the acquisition and analysis techniques used in this study allowed us to obtain more consistent results for the perfusion fraction, f, the diffusion coefficient, D, and the pseudo-diffusion coefficient, D*, than previous studies. Parameter maps of D and f were reflective of placental structure and composition. Such maps can be useful tools in identifying tissue differences and give important insight into the placental hemodynamic systems. This technique could become instrumental in the assessment and management of abnormal pregnancies.

15:00 4565. Isotropic 3D T2-Weighted MR Imaging for Female Pelvis with 3 Tesla MRI: Feasibility Study

Junko Takahama¹, Satoru Kitano¹, Aki Takahashi¹, Nagaaki Marugami¹, Megumi Takewa¹, Takahiro Itoh¹, Toshiaki Taoka¹, Kimihiko Kichikawa<sup>1

1</sup>Radiology, Nara Medical University, Kashihara, Nara, Japan

The aim of this study was to compare the quality of images obtained with 3D T2-weighted sequence with the quality of conventional 2D T2-weighted images on 3.0-T MRI. Thirty consecutively registered patients were reviewed and analyzed quantitative measures of contrast and image quality. Three-dimensional volumetric T2-weighted images on 3.0T MRI are of content quality and give better anatomical recognition than conventional 2D images and have the added advantage of multiplanar and postprocessing capabilities.

MR Upper Abdomen I

Hall B Monday 14:00-16:00 Computer 92

14:00 4566. Semi-Quantitative Analysis of Normal Pancreas and Pancreatic Carcinoma with Dynamic Contrast-Enhanced MR Imaging on a 3.0T System

Xiao Hong Ma¹, Chun Wu Zhou¹, Fei Sun², Xin Ming Zhao¹, Han Ouyang¹, Hong Mei Zhang<sup>1

1</sup>Diagnostic Radiology, Cancer Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, China; ²Shanghai Guided Medical Scientific Co. Ltd., Shanghai, China

Our study target to semi-quantify the perfusion parameters of normal pancreas and pancreatic carcinoma with three-dimension (3D) high spatial and time resolution dynamic contrast enhanced (DCE) MRI on a 3.0T MR system. 31 patients who need abdomen contrast enhancement scan but with normal pancreas and 34 pancreatic carcinoma patients underwent DCE-MRI on a 3.0T MR system with 8-channel body coil. The perfusion parameters were measure including signal enhancement ratio at 30 seconds and 90 seconds after injection (SER30, SER90), positive enhancement integral (PEI), time to peak (TTP) and maximum slope of increase (MSI). There is no regional perfusion difference between the head, body and tail of normal pancreas, while there is significant difference between lesion and non-lesion area of pancreatic carcinoma, and between normal pancreas and non-lesion area of pancreatic carcinoma.

14:30 4567. Effects of Oxygen Inhalation on T1 Relaxation Times in Abdominal Solid Organ

Kyung Ah Kim¹, Mi-Suk Park¹, Eun Ju Kim², Myeong-Jin Kim¹, Jin-Young Choi¹, Hye-Suk Hong¹, Ki Whang Kim<sup>1

1</sup>Radiology, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea, Republic of; ²Clinical science, MR, Philips Healthcare, Seoul, Korea, Republic of

We investigated the effect of the oxygen inhalation on relaxation times of T1 in abdominal solid organs, including liver, pancreas, spleen, and kidney. The inhalation of oxygen caused T1 shortening in the pancreas, kidney and spleen, which have predominant arterial blood supply, whereas no significant effect was noted in the liver, which has predominant portal venous blood supply. Our results indicate that MRI is feasible to detect changes with oxygen inhalation, which differs considerably among organs, in a noninvasive fashion. As a clinical application, the effect of oxygen on various normal and pathologic tissues may be used as a biomarker of arterial flow, oxygen delivery to organs, and hypoxic status.

15:00 4568. Aged Vs. Fresh Blood for the Treatment of Hemorrhagic Shock; Differential Effect on Liver Outcome and Possible Mechanism

Idit Matot¹, Miriam Katz², Orit Pappo³, Nathalie Corchia⁴, Gregory Barshtein⁵, Shaul Yedgar⁵, Rinat Abramovitch, <sup>6

1</sup>Department of Anesthesiology & Intensive Care, Tel Aviv, Sourasky Medical Center, Tel Aviv, Israel; ²Department of Anesthesiology, Rabin Medical Center, Petach Tiqva, Israel; ³Pathology, Hadassah Hebrew University Medical Center, Jerusalem, Israel; ⁴he Goldyne Savad Institute of Gene Therapy, Hadassah Hebrew University Medical Center, Jerusalem, Israel; ⁵Department of Biochemistry, Hebrew University, Jerusalem, Israel; ⁶MRI/MRS lab HBRC, Hadassah Hebrew University Medical Center, Jerusalem, Israel

Concerns have recently been raised about the safety of transfusing stored-blood. Several studies have suggested that the risk of complications increases when transfused blood has been stored for long period. The liver is a target for injury in low flow states associated with trauma and hemorrhage. We studied the effect of blood resuscitation (fresh vs. Stored-blood) on liver injury. In rats, transfusion of blood stored longer than 4 days increased liver injury. This was associated with significant changes in the viscoelastic characteristics of the stored-blood and unrelated to the oxygen-carrying-capacity, cytokines in the stored-blood or the RBC/endothelial cells adherence properties.

15:30 4569. Characterization of Cirrhotic Nodules with Gadoxetic Acid-Enhanced MR Imaging: The Efficacy of Hepatocyte-Phase Imaging

Chen-Te Chou^1,2, Ran-Chou Chen<sup>2,3

1</sup>Radiology, Chang-Hua Christian Hospital, Chang-Hua, Taiwan; ²Biomedical Imaging and Radiological Science, National Yang-Ming Medical University, Taipei, Taiwan; ³Radiology, Taipei City Hospital, Taipei, Taiwan

The study was to evaluate the efficacy of hepatocyte-phase imaging in characterization of focal hepatic lesions among cirrhotic liver using gadoxetic acid enhanced MRI. Our results revealed SNRs/CNRs of HCC were significantly decreased in hepatocyte phase (P<0.05) and the benign DN showed no significant difference (P>0.05). Severe additional HCC were diagnosed by hepatocyte-phase imaging. The diagnostic performance is significantly higher in the imaging set with hepatocyte-phase imaging (P=0.016). In conclusion, combination of gadoxetic acid-enhanced dynamic study and hepatocyte-phase imaging could provide better diagnostic performance than dynamic study only in characterization of focal liver lesion among cirrhotic liver.