Electronic Posters: Cardiovascular

Wednesday 13:30-15:30 Computer 30

13:30 3592. Association Between Left Ventricle Sympathetic Innervation and Torsion in Patients with Type 1 Diabetes

Scott David Swanson¹, Gisela C. Mueller¹, David Raffel¹, Dorthea Happ¹, Claire S. Duvernoy^2,3, Rodica Pop-Busui<sup>4

1</sup>Department of Radiology, University of Michigan, Ann Arbor, MI, United States; ²Cardiology Section, VA Ann Arbor Health Care System, United States; ³Department of Internal Medicine, University of Michigan; ⁴Department of Internal Medicine; Division of Metabolism, Endocrinology and Diabetes, , University of Michigan

We compare left ventricular torsion as measured by cardiac MR tagging with sympathetic denervation as measure by PET and find that increased torsion is correlated with denervation.

14:00 3593. Myofiber Developmental Plasticity in Fetal and Adult Pig Hearts Delineated with Diffusion Tensor MRI

Lei Zhang¹, Huiying Zhang¹, Gregory M. Lanza¹, Samuel A. Wickline¹, Junjie Chen<sup>1

1</sup>Washington University School of Medicine, St. Louis, MO, United States

Cardiac function in pre and post-natal stages are different because of reduced workload of right ventricle relative to left ventricle after birth. We hypothesize that myocardial fiber structure in fetal hearts differs from that of adult hearts as a response to the change of cardiac function. Diffusion tensor MRI was used to quantitatively evaluate myofiber structure in mid-gestation, pre-born and adult pig hearts. Helix angle and transverse angle in septum and LV/RV fusion sites were compared between the three groups. Our results showed that contributions of RV myofibers to septum was higher in fetal pig hearts than adult pig hearts. The current observations were in agree with change of cardiac function and reflect the plasticity of myocardial fiber development in response to programmed differential contractile functions before and after birth.

14:30 3594. Accelerated Simultaneous Multi-Slice Cardiac Cine Imaging Using a Combination of CAIPIRINHA and Compressed Sensing

Daniel Stäb¹, Tobias Wech¹, Christian Ritter¹, Dietbert Hahn¹, Herbert Köstler<sup>1

1</sup>Institute of Radiology, University of Wuerzburg, Wuerzburg, Bavaria, Germany

A combination of CAIPIRINHA simultaneous multi-slice imaging with Compressed Sensing is presented. A technique is generated, effectively accelerating the imaging procedure in slice and phase encoding direction. Several slices are excited simultaneously and shifted with respect to each other in the FOV using RF phase cycles, while k-space is undersampled randomly in incoherent fashion. In the reconstruction process, Compressed Sensing is used to eliminate incoherent artifacts, while a parallel imaging reconstruction separates the simultaneously excited slices. The method shows potential for high quality multi-slice imaging with high acceleration factor.

15:00 3595. SNR Evaluation of 32 Channel Cardiac Coils in DENSE MRI at 1.5 and 3T

Andreas Sigfridsson^1,2, Henrik Haraldsson^1,2, Tino Ebbers^1,2, Hans Knutsson, ²³, Hajime Sakuma<sup>4

1</sup>Clinical Physiology, Linköping University, Linköping, Sweden; ²CMIV, Linköping University, Linköping, Sweden; ³Biomedical Engineering, Linköping University, Linköping, Sweden; ⁴Radiology, Mie University, Tsu, Mie, Japan

The in-vivo SNR for DENSE MRI was evaluated for 32 channel cardiac coils compared to standard 5 and 6 channel coils at 1.5 and 3T. On average, the 32 channel coils provided 50% higher SNR. The SNR improvement was more pronounced at 3T than at 1.5T, and closest to the chest wall. The higher SNR provides the opportunity for DENSE imaging in a longer portion of the cardiac cycle.