Electronic Posters: Cardiovascular

Flow Quantification & Vessel Function

Hall B Monday 14:00-16:00 Computer 37

14:00 3696. 3D Flow Characteristics in Ventricular Assist Devices: Impact of Valve Geometry and Operating Conditions

Christoph Benk¹, Ramona Lorenz², Jürgen Hennig^2,3, Friedhelm Beyersdorf¹, Jan G. Korvink, ^3,4, Michael Markl<sup>2

1</sup>Dept. of Cardiovascular Surgery, University Hospital, Freiburg, Germany; ²Dept. of Diagnostic Radiology, Medical Physics, University Hospital, Freiburg, Germany; ³FRIAS, Freiburg Institute for Advanced Studies, Freiburg, Germany; ⁴Laboratory for Simulation, IMTEK - Institute of Microsystem Technology, Freiburg, Germany

The use of paracorporeal ventricular assist devices (PVAD) has become a well-established procedure for patients with cardiogenic shock or who need biventricular support. However, implantation of Ventricular assist devices (VADs) is often associated with severe complications such as thrombosis inside the VAD and subsequent embolic events. It was therefore the purpose of this study to use flow sensitive 4D MRI for a detailed analysis of local and global 3D flow dynamics in a clinical routine VAD to study the effect of different system adjustments and valve designs on flow patterns.

14:30 3697. Time-Resolved Spin-Labeled Balanced SSFP Cineangiography for Visualizing Intracardiac Shunt

Federico E. Mordini¹, Ioannis Koktzoglou¹, Robert R. Edelman<sup>1

1</sup>Radiology, NorthShore University HealthSystem, Evanston, IL, United States

Existing methods for intracardiac shunt evaluation have important technical limitations. We developed a time-resolved spin-labeled cineangiographic technique (SLC) to image tagged blood within the heart for visualization of intracardiac shunt. Ten subjects with known atrial septal defects (ASD) were evaluated. Tagged inflowing blood was depicted with high signal intensity (SI) while non-tagged blood was suppressed. Flow was visualized crossing the atrial septum both inplane and throughplane. In conclusion, SLC is a non-contrast, non-velocity dependent method for visualizing RF-tagged blood flowing through cardiac chambers. SLC successfully depicted intracardiac shunting in all patients. SLC has potential use in the detection and pre-procedural assessment of ASD.

15:00 3698. Evaluation of Diastolic Function with Flow Quantification Phase Contrast Cardiac Magnetic Resonance Imaging

Jeremy Douglas Collins¹, Philip Anthony Hodnett¹, Timothy Anthony Scanlon¹, Amir H. Davarpanah¹, Aya Kino¹, Karin Dill¹, Sven C. Zuehlsdorff², James C. Carr<sup>1

1</sup>Radiology, Northwestern University, Chicago, IL, United States; ²Radiology, Siemens Healthcare, MR Research and Development, Chicago, IL, United States

Cardiac magnetic resonance is the reference standard for assessment of infiltrative heart disease and systolic function. The ability to assess diastolic dysfunction would enable comprehensive assessment of cardiac function. We evaluated 36 patients and 4 volunteers with flow quantification phase contrast imaging, comparing to Doppler echocardiography. Phase contrast imaging correctly classified all patients with grade I diastolic dysfunction. Differentiating patients with grade II dysfunction from normal diastolic function was not possible, although stratification based on E wave deceleration time was promising. A dedicated acquisition to assess the E’ lateral annulus velocity may be useful in this regard.

15:30 3699. Highly Accelerated Cine Phase-Contrast Flow Measurements Using k-T PCA with Spatial Compartments

Daniel Giese^1,2, Verena Knobloch¹, Henrik Pedersen³, Tobias Schaeffter², Sebastian Kozerke<sup>1,2

1</sup>Institute for Biomedical Engineering, Univeristy and ETH Zurich, Zurich, Switzerland; ²Division of Imaging Sciences, King's College London, London, United Kingdom; ³Functional Imaging Unit, Glostrup Hospital, Glostrup, Denmark

In this work, we present an extension of k-t PCA taking into account temporal correlations in spatial compartments. The compartment method is shown to significantly outperform conventional k-t PCA at high reduction factors. Using the approach up to 10- fold net acceleration of single-directional phase-contrast velocity mapping in the ascending and descending aorta is demonstrated with excellent agreement relative to fully sampled data even if only a single receive coil is available.