Electronic Posters: Cardiovascular

Wednesday 13:30-15:30 Computer 29

13:30 3576. Increased Left Ventricular Torsion in Hypertrophic Cardiomyopathy Mutation Carriers with Normal Wall Thickness

Iris Rüssel¹, Wessel Brouwer¹, Tjeerd Germans¹, Paul Knaapen¹, J Tim Marcus¹, Jolanda van der Velden¹, Marco Götte¹, Albert van Rossum<sup>1

1</sup>VU University Medical Center, Amsterdam, Netherlands

Hypertrophic cardiomyopathy (HCM) is caused by mutations in mainly sarcomeric genes. Increased left ventricular (LV) torsion has been observed in patients with manifest hypertrophy, but abnormalities in myocardial contractility might already be present in HCM mutation carriers with normal wall thickness. Therefore, LV torsion and endocardial circumferential strain were studied in HCM mutation carriers using MRI tagging. Increased LV torsion and torsion to endocardial circumferential strain-ratio were found in carriers with respect to controls. The observed difference might be due to HCM-related endocardial myocardial dysfunction.

14:00 3577. Reconstruction of Line Tagged Cardiac Images by Compressed Sensing Algorithm Using Contourlet Transform from Appropriate K-Space Sampling

Sung-Min Gho¹, Narae Choi¹, Dong-Hyun Kim<sup>1,2

1</sup>Electrical and Electronic Engineering, Yonsei University, Shinchon-Dong, Seoul, Korea, Republic of; ²Radiology, Yonsei University, Shinchon-Dong, Seoul, Korea, Republic of

RF tagging in cardiac imaging can be used to analyze the heart wall motion. There is always a push towards higher spatial and/or temporal resolution to enable more accurate quantification. This work is on combining line tagged cardiac imaging with the compressed sensing (CS) algorithm and exploiting the distinct k-space feature of tagged images.

14:30 3578. Characterization of Vortex Flow in the Left Ventricle by Phase Contrast Magnetic Resonance Imaging

Samuel Ting¹, Paaladinesh Thavendiranathan¹, Helene Houle², Gianni Pedrizzetti³, Subha V. Raman¹, Mani Vannan¹, Orlando Simonetti<sup>1

1</sup>The Ohio State University, Columbus, OH, United States; ²Siemens Medical Solutions, Mountain View, CA, United States; ³University of Trieste, Trieste, Italy

Characterization of vortex formation and flow within the heart may be used as tool for diagnosing and understanding pathophysiological conditions of the heart. We present preliminary results demonstrating that phase contrast magnetic resonance imaging may be used to quantitatively evaluate and characterize formation of vortices within blood flow in the left ventricle of the heart.

15:00 3579. Quantitative Assessment of Atrioventricular Plane Displacement in Normals and Diastolic Heart Failure-A Cine MRI Study.

Reena Anand¹, Sohae Chung¹, Sharath Bhagavatula, Leon Axel<sup>1

1</sup>Radiology, NYU Langone Medical Center, New York, NY, United States

In conventional cine MRI, it is observed that the atrioventricular (AV) plane of the heart descends towards the apex during systole and moves back towards the atrium during the diastole. The displacement of the AV plane through the cardiac cycle is an expression of the systolic and diastolic performance of the heart, so that it can be used to detect early diastolic dysfunction. In this study, we have investigated the potential of MRI measurement of left AV plane displacement as a means to assess diastolic dysfunction.