Electronic Posters: Cardiovascular

Thursday 13:30-15:30 Computer 29

13:30 3580. Combination of Through-Plane Tissue Phase Mapping and SPAMM for 3D Cardiac Motion Assessment

Anja Lutz¹, Axel Bornstedt¹, Robert Manzke², Gerd Ulrich Nienhaus³, Volker Rasche<sup>1

1</sup>University Hospital of Ulm, Ulm, BW, Germany; ²Philips Research Europe, Hamburg; ³Institute of Technology, University of Karlsruhe, Germany

Cardiac motion assessment can be performed by tagged imaging combined with HARP analysis and with tissue phase mapping (TPM). The tagging approach enables fast assessment of the in-plane motion component, where TPM can be applied for full assessment of the motion vector in 3D but requires at least fourfold measurement time. In this contribution tagging is combined with TPM for 3D + time motion assessment. There is no information loss of the through plane motion, when tag lines are applied. The combination can be used to reduce imaging time for motion encoding in 3D.

14:00 3581. MRI Compatible Treadmill

Eric L. Foster¹, Mihaela Jekic^1,2, Jacob A. Bender^1,2, John W. Arnold³, Subha V. Raman^1,4, Orlando P. Simonetti<sup>1,5

1</sup>Dorothy M. Davis Heart and Lung Research Institute, The Ohio State University, Columbus, OH, United States; ²Biomedical Engineering, The Ohio State University; ³Agricultural Technical Institute, The Ohio State University; ⁴Internal Medicine, The Ohio State University; ⁵Internal Medicine and Radiology, The Ohio State University

Treadmill exercise testing in conjunction with MRI may offer improved diagnosis of heart disease compared to current modalities; however, traditional treadmills can not operate safely within the MR environment. An MR compatible treadmill was developed using hydraulic drive and elevation systems and fiber-optic data transmission, allowing the treadmill to be positioned immediately adjacent to the MR examination table. The treadmill successfully passed MR safety and compatibility tests. Six healthy volunteers were exercised to peak cardiovascular stress and transferred to the MR table. Real time cine imaging was completed within 38±6.4 s, meeting the AHA guideline of imaging within 60 s.

14:30 3582. Early Diastolic Strain-Velocity Temporal Relationship Assessment Using SPAMM-PAVE

Ziheng Zhang¹, Donald P. Dione¹, Peter B. Brown¹, Erik M. Shapiro¹, Chengqing Wu², Robert Todd Constable¹, Albert J. Sinusas¹, Smita Sampath<sup>1

1</sup>Yale University School of Medicine, New Haven, CT, United States; ²Yale University School of Public Health, New Haven, CT, United States

A novel MR imaging technique, spatial modulation of magnetization with polarity alternated velocity encoding (SPAMM-PAVE), is presented to investigate the left ventricular early diastolic strain-velocity relationships. This technique provides simultaneous measurements of 1-D myocardial displacement and chamber blood velocity with a high temporal resolution of 14 ms, sensitive to early diastolic events undetectable by current state-of-the-art methods. The reliability of the measurement is demonstrated by an intra-subject study of a normal volunteer. The interplay of regional volumetric changes in the left ventricle in response to filling patterns is investigated through comparing the regional strain and blood inflow velocity curves in 8 normal volunteer studies.

15:00 3583. 4CH TX/RX Surface Coil for 7T: Design, Optimization and Application for Cardiac Function Imaging

Matthias Alexander Dieringer^1,2, Wolfgang Renz, ^1,3, Tomasz Lindel, ^1,4, Frank Seifert, ^1,4, Tobias Frauenrath¹, Helmar Waiczies, ^1,4, Florian von Knobelsdorff-Brenkhoff⁵, Davide Santoro¹, Werner Hoffmann⁴, Bernd Ittermann, ^1,4, Jeanette Schulz-Menger^2,5, Thoralf Niendorf<sup>1,2

1</sup>Berlin Ultrahigh Field Facility, Max-Delbrueck-Center for Molecular Medicine, Berlin, Germany; ²Experimental and Clinical Research Center (ECRC), Charité Campus Buch, Humboldt-University, Berlin, Germany; ³Siemens Healthcare, Erlangen, Germany; ⁴Physikalisch-Technische Bundesanstalt (PTB), Berlin, Germany; ⁵CMR-Unit Charité Campus Buch, Berlin, Germany

Practical impediments of ultra high field cardiovascular MR (CVMR) can be catalogued in exacerbated magnetic field and radio frequency (RF) inhomogeneities, susceptibility and off-resonance effects, conductive and dielectric effects in tissue, and RF power deposition constraints, which all bear the potential to spoil the benefit of CVMR at 7T. Therefore, a four element cardiac transceive surface coil array was developed. Cardiac imaging provided clinically acceptable signal homogeneity with an excellent blood myocardium contrast. Subtle anatomic structures, such as pericardium, mitral and tricuspid valves and their apparatus, papillary muscles, and trabecles were accurately delineated.