Electronic Posters: Cardiovascular

Tuesday 13:30-15:30 Computer 31

13:30 3604. Evaluating Left Ventricular Wall Motion Abnormalities Using Centerline Trajectory Mapping

Ting Song^1,2, Alexander I. Bustamante³, Jeffrey A. Stainsby⁴, Maureen N. Hood^2,5, Vincent B. Ho<sup>2,5

1</sup>GE Healthcare Applied Science Laboratory, Bethesda, MD, United States; ²Radiology, Uniformed Services University of the Health Sciences, Bethesda, MD, United States; ³Cardiology, National Navy Medical Center, Bethesda, MD, United States; ⁴GE Healthcare Applied Science Laboratory, Toronto, ON, Canada; ⁵Radiology, National Navy Medical Center, Bethesda, MD, United States

This paper presents Centerline Trajectory Mapping (CTM) method as a quantitative tool for characterization of focal and global wall motion abnormalities using long axis views of the left ventricle. Evaluation of CTM with myocardial delayed enhancement imaging and echocardiography with great consistency in wall motion abnormality detection. The proposed method does not add any extra scans to existing clinical cardiac MR routine and can be utilized in retrospective studies.

14:00 3605. Orientation and Magnitude of the Left Ventricular Principal Strains Are Sensitive to Ischemic Injury

Chun Xu¹, Kevin Koomalsingh¹, Gamaliel Isaac², Joseph H. Gorman², Robert C. Gorman², Lawrence Dougherty², James Pilla<sup>2

1</sup>University of Pennsylvania , Philadelphia, PA, United States; ²University of Pennsylvania, Philadelphia, PA, United States

Accurate assessment of regional and global left ventricular (LV) functions is critical for ischemic heart disease. The orientation and the magnitude of the myocardial principal strains have been shown to be sensitive to ischemic development. This study presents a method to fully characterize the alterations in the magnitude and orientations of principal strains in a pig left ventricle. The computaed decreases in principal strains due to introduced infarct are confirmed by implanted markers and perfusion image, indicating impaired transmural thickening and circumferential shortening. Characterization of the remote, border zone and infarct 3D strain is paramount in understanding infarct expansion and in the development of therapies to mitigate remodeling.

14:30 3606. Cardiac Valve Position Prediction in CINE-BSSFP Images Using SURF

Hendrikus Joseph Alphons Crooijmans¹, Philippe C. Cattin², Oliver M. Weber^1,3, Klaus Scheffler<sup>1

1</sup>Division of Radiological Physics, Department of Medical Radiology, University of Basel Hospital, Basel, Switzerland; ²Medical Image Analysis Center (MIAC), University of Basel, Basel, Switzerland; ³Siemens Healthcare, Zürich, Switzerland

The interest point detector and region descriptor SURF finds features in every image/phase of a series of CINE-bSSFP images. By the help of user input, the best feature is selected in a Matlab program and corresponding features are automatically detected. If no feature is found within preset limits, it is created by linear interpolation. User indicated points of interest are described as a function of the position and diameter of the feature (all in the first image/phase), and can therefore be repositioned based on the corresponding features in the succeeding images/phases. This method provides reliable fast online valve position detection.

15:00 3607. Comparison of Left Function Assessment Using Phonocardiogram and Electrocardiogram Triggered 2D SSFP CINE MR Imaging at 1.5 T and 3.0 T

Tobias Frauenrath¹, Meike Becker^2,3, Fabian Hezel¹, Gabriele A. Krombach², Ute Kremer², Jeanette Schulz-Menger^1,3, Thoralf Niendorf<sup>1,3

1</sup>Berlin Ultrahigh Field Facility, Max-Delbrueck Center for Molecular Medicine, 13125 Berlin, Germany; ²Department of Radiology, University Hospital, RWTH, 52074 Aachen, Germany; ³Experimental and Clinical Research Center (ECRC), Charité Campus Buch, Humboldt-University, 13125 Berlin, Germany

As high-field cardiac MRI (CMR) becomes more widespread the propensity of ECG to distortions and mistriggering increases and with it the motivation for a cardiac triggering alternative. Hence, this study explores the suitability of acoustic cardiac triggering (ACT) for left ventricular (LV) function assessment in healthy subjects at 1.5T and 3.0T.