Figure (E)F-1

Figure (E)F-1. Metabolite concentrations (mM) and metabolite ratios vs. age in years at MRS test for patients () and controls (): (A) NAA in right frontal white matter (RFW), (B) NAA in left frontal white matter (LFW), (C) NAA in right hippocampus (RHIP) and (D) NAA/ CR in RHIP. Metabolite concentrations: NAA = N- acetyl aspartate and CR= creatine.
Figure (E)F-2. Metabolite concentrations (mM) and metabolite ratios vs. age in years at MRS for patients () and control subjects () or age at initiation of HIV treatment for patients: (A) INS in right frontal white matter (RFW) vs. age at MRS, (B) INS vs. age at MRS in left frontal white matter (LFW), (C) INS/CR vs. age at MRS in RFW, and (D) INS vs. age of HIV treatment in RFW for HIV –infected children only. Metabolite concentrations: INS=myo-inositol, CR=creatine.
Figure (E)F-3. Metabolite concentrations (mM) and concentration ratios vs. log₁₀ viral load (HIV RNA copies/ mL) for patients: (A) INS in right frontal white matter (RFW), (B) CHO/CR in RFW, (C) CHO in midfrontal gray matter (MFG), and (D) INS in right basal ganglia (RBG). Metabolite concentrations: INS=myo-inositol, CHO=choline, CR=creatine.
Figure (E)F-4. Metabolite concentrations (mM) and concentration ratio vs. neuropsychological assessments for patients () and control subjects (): (A) CHO in right hippocampus (RHIP) vs. Children’s Memory Scale after long delay (CMS Long D), (B) INS/CR in right frontal white matter (RFW) vs. Purdue Pegboard Dominant Test (Purdue D), (C) INS in RHIP vs. Purdue Pegboard Nondominant Test (Purdue ND). Metabolite concentrations: INS= myo-inositol, CHO=choline, CR=creatine.
Figure (E)F-5. Metabolite concentrations (mM) and concentration ratios vs. neuropsychological assessments for patients () and control subjects (): (A) CHO/CR in right frontal white matter (RFW) vs. Children’ Depression Inventory: Total score (CDI: Total) (B) INS/CR in RFW vs. Expressive One Word Picture Vocabulary Test (EOWPVT), and (C) INS in left frontal white matter (LFW) vs. (EOWPVT). Metabolite concentrations: INS= myo-inositol, CHO= choline, CR=creatine.
Figure (E)F-6. Metabolite concentrations (mM) vs. Children’s Memory Scale test after long delay (CMS Long D) for patients () and control subjects (): (A) INS in right frontal white matter (RFW), (B) INS/CR in RFW. Metabolite concentrations: INS = myo-inositol, CR = creatine.