Is he mentally ill?


Vascular dementia—multi-infarct dementia



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Vascular dementia—multi-infarct dementia

  • Vascular dementia—multi-infarct dementia

    • Similar clinical picture to Alzheimer's
    • Series of infarcts destroy neurons over expanding brain regions
    • After 50; more common in men
    • About 19% of all dementia cases
    • Vulnerable to death from stroke
    • Mood disorders more common than in AD
    • Can manage cerebral arteriosclerosis to some extent


Creutzfeld-Jakob Disease—slow acting virus that may live in the body for years; then rapid course

  • Creutzfeld-Jakob Disease—slow acting virus that may live in the body for years; then rapid course

  • Dementia from HIV-1 infection

    • HIV can result in destruction of brain cells
    • May lead to psychotic phenomena
    • Damage may occur throughout brain, but tends to be localized in subcortical regions
    • 30-60% of untreated pts with HIV will develop AIDS-related dementia; with current antiviral tx, rate reduces to 20%


Central feature is strikingly disturbed memory or amnesia

  • Central feature is strikingly disturbed memory or amnesia

  • Immediate recall and memory for remote events is usually preserved

  • Short term memory is typically very impaired

  • Confabulation is common

  • Overall cognitive functioning is relatively intact

  • Korsakoff’s Syndrome—follows severe alcohol abuse

    • May also be caused by head trauma, stroke, surgery in the temporal lobe, hypoxia
    • Depending on cause, may abate wholly or partially


Affects more than 2 million per year

  • Affects more than 2 million per year

  • Most common cause—MVA, followed by falls, assaults, sports injuries

  • Men 15-24 are at greatest risk

  • Three types of head injury—closed, penetrating, skull fractures

  • Immediate acute reactions—unconscious, disruption of circulatory, metabolic, and neurotransmitter regulation

  • Retrograde and anterograde amnesia are common

  • Person typically passes through stupor and confusion on way to recovering clear consciousness

  • Coma may occur

  • Treatment—prompt medical attention is required

    • Mild concussions improve quickly
    • Minority—personality change
    • Severe injury—poor prognosis
    • 24% of TBI develop post-traumatic epilepsy, presumably because of the growth of scar tissue


Take a developmental perspective

  • Take a developmental perspective

    • Tasks a child should be handling and see how they’re doing
    • All of this is culturally related.
    • Often an attempt to adapt to negative circumstances.
  • Issues in working with children:

    • 1) Limited capacity to understand in children
    • 2) More difficulty coping as cannot put problems into perspective of a past and future
    • 3) Use unrealistic concepts to explain things (don’t understand death, etc)
    • 4) Dependent on others for help
  • Adultomorphism

  • 1/5 children has a disorder that disrupts functioning. 1/10 has a disorder that severely impairs functioning.

  • Loosely categorized into externalizing and internalizing.



Inattention—doesn’t pay attention/makes careless mistakes

  • Inattention—doesn’t pay attention/makes careless mistakes

    • Doesn’t listen when spoken to
    • Doesn’t follow through on instructions
    • Difficulty getting organized
    • Avoids things that require concentration
  • Hyperactive

    • Fidgets
    • Can’t stay seated
    • Runs or climbs excessively/inappropriately
    • Can’t play quietly
    • On the go/driven by a motor
  • Girls tend to have PI, boys PH or C; 2-3X more common in boys (not 6-9x as text says)

  • Other issues: 7-15 points lower IQ

    • Social problems
    • Emotional competence
    • Those with PI are more likely to have internalizing problems, LD, slow pace of problem solving
  • Prevalence is 3-5% of school aged kids

  • 50-70% continue to have problems into adolescence and adulthood; less hyperactivity with age

  • Poorer prognosis when comorbid with CD

  • As adults—more car accidents, higher risk of substance abuse



Causes: Multiple biological and psychological causes.

  • Causes: Multiple biological and psychological causes.

    • Frontal lobe deficits
    • Runs in families
    • Mothers report more stress; negative parenting
    • Not caused by diet, additives
  • Treatments: 70-80% on stimulants improve

    • Side effects: decreased appetite, insomnia, abdominal pain, headaches, crying spells, stunts growth—drug holidays. Don’t improve social skills or academics.
    • Behavior modification
    • Combination most effective
    • Social skills training, cognitive-behavioral effective after sx under control


Typically kids 3-7

  • Typically kids 3-7

  • Poor control of emotions

  • Noncompliant

  • Argumentative with parents and teachers

  • Conflicts with peers

  • Tantrums

  • Problem with ODD: some sx are very common

  • Majority of kids with ODD will go on to show conduct problems.

  • Risk factors: family discord, low SES, antisocial beh. in parents



More serious behavior problems

  • More serious behavior problems

  • Repetitive, persistent problems with behaviors that are potentially harmful to

  • child, others, or property

  • Sx—physical fights, weapons, stealing with or without confrontation, fires, sexual aggression, truancy, lying, running away overnight, breaking into house, bldg or car, bullying, cruelty to animals or people

  • Demographics vary greatly. More common in boys. Boys have more aggressive subtypes. Girls tend toward less confrontational sx.

  • Prognosis factors

    • Childhood onset vs. adolescence-limited
    • Degree of callous-unemotional traits
    • Big three sx: fires, cruelty to animals, cruelty to people
    • Socialized vs. unsocialized
  • Early onset is linked to APD (25-40%)

    • Even if not APD, often associated with life problems such as divorce, joblessness, and abusive parenting


Biological

  • Biological

  • Danish adoption study—parent history of criminality and % of kids convicted of conduct offense

  • Bio

  • Yes No

  • Adop yes 25 14

  • No 20 13

  • Generally lower levels of adrenaline—low arousal

  • Psychosocial causes—

    • Gerald Patterson—coercive cycles—kid is obnoxious until parent relents; parents engage in negative parenting
    • Parents of CD kids more likely to behave in ways that encourage development of coercive styles; criticize more, issue more commands
    • Adverse environmental factors make it harder to use positive child rearing skills—substance abuse, marital distress, violence, poverty, social isolation, death of a family member
    • Self-perpetuating—deviancy training
    • Difficult temperament leads to poor attachment
  • Hostile attribution bias



Society picks punitive rather than treatment based approaches but…

  • Society picks punitive rather than treatment based approaches but…

  • Must be multimodal

  • Need to address family issues

  • Behavioral programs

  • All most effective at young ages



SAD—characterized by worry that caregiver will get hurt/child hurt if not with caregiver

  • SAD—characterized by worry that caregiver will get hurt/child hurt if not with caregiver

    • Normal in young kids—not a disorder until past normal period, generally 6-9
    • School avoidance present in ¾
    • Often have specific phobias as well
    • May be acute onset following big life changes; may wax and wane
    • More common in girls
  • Generalized Anxiety Disorder

    • Pervasive diffuse worry
    • 95% worry all the time
    • ½ meet MDD criteria
    • Seems to be chronic


Selective mutism—

  • Selective mutism—

    • Persistent failure to speak in specific social situations
    • Can speak and understand language
    • Rare, most common at school entry
    • More common in families where taciturn behavior is prominent
    • Stress and family environmental factors
  • Phobias—simple—consider in context of kids’ normal fears

    • Fears can be adaptive, but can become phobias
      • Unusual age of onset
      • Intensity
      • Persistence of fear
      • Type of fear—rational or not
    • Morris and Kratchowill (1989)
      • Toddlers—separation, animals, dark
      • Preschool—strangers, bodily harm, toddler fears
      • School age-being alone, imaginary beings, violence, death, dark, injury, storms, teasing
      • Teens—peer rejection, achievement, family problems, war, poverty, AIDS


Causal factors in anxiety disorders:

  • Causal factors in anxiety disorders:

    • Modeling of anxious parents
    • Indifferent or detached parent may instill insecurity
    • Temperament
    • Cultural factors
    • Genetic link—anxiety in parents predicts anxiety in kids
  • Treatment:

    • Meds—common, not yet well established. Possibly prozac
    • Behavior therapy—focused on assertiveness training and desensitization
    • Cognitive-behavioral tx


Adult criteria are used, but there are limitations in this

  • Adult criteria are used, but there are limitations in this

    • Kids are less adept at expressing the cognitive symptoms
    • Childhood depression is not factor analytically distinct from anxiety
    • Ability to feel and express shame and guilt does not emerge until age 7 or so
    • Many more somatic complaints in kids
    • Social withdrawal is common, but this looks different in children—not able to choose to stay home
    • Irritability is common instead of overtly depressed mood
    • Hallucinations are more common in children than adults
    • Wt. issues may be failure to make expected gains instead of wt. loss
  • Younger kids—depression is more common in boys or equal in boys and girls

  • By adolescence—more common in girls

  • Prevalence==.4-2.5% in children, 4-8.3% for adolescents



Causal factors

  • Causal factors

    • Genetic component –higher risk if parent is depressed
    • Early exposure to traumatic events, including death of a parent
    • Parent-child interaction in transmission of depressed affect
    • Cognitive—global, internal, stable
  • Treatments—

    • Antidepressants are not well established. Some studies show no effect, others show a moderate effect. Concern about side effects and suicidal thoughts.
    • Suicide appraisal is important—longitudinal study of 8-13 yo who were depressed found that 1/3 made suicide attempts in the next 7 yrs.
      • Perhaps 7%-1/10 of all teens make a suicide attempt
  • Cognitive behavioral techniques are effective



75 outcome studies

  • 75 outcome studies

  • Average outcome for a treated child was 2/3 of an SD better than untreated kids

  • Beh>nonbeh

  • Play or non-play did not matter

  • Parents or no parents did not matter

  • Experience, education and sex of therapist did not matter

  • Greatest improvements for specific problems, global issues like self-esteem and social adjustment improved less



Group of severely disabling conditions

  • Group of severely disabling conditions

  • Result of structural differences in the brain

  • Examples include Asperger’s and Autism

  • Prevalence unclear, but increasing, maybe 3.2% of clinic cases



Three primary features: noncommunicative speech, social isolation, need for sameness

  • Three primary features: noncommunicative speech, social isolation, need for sameness

  • Appears as early as 1 yr to 18 months when kid are not making eye contact

  • Social deficit-do not want physical contact, do not show affection

  • Self-stimulation—stereotyped movements

  • Panic if routine is changed

  • Intellectual ability—have thought that most have IQs in MR range. New studies questions whether this is so or whether it is an artifact of testing.

  • Theory of mind deficits

  • Less time in symbolic play

  • Not the same as schizophrenia

  • 4x more common in boys

  • About 5% of autistics are savants—isolated skills of great talent with no known cause or training



Not caused parents actions (refrigerator mothers—retreat in autistic fortress)

  • Not caused parents actions (refrigerator mothers—retreat in autistic fortress)

  • Not caused by vaccines. Multiple big studies.

  • Precise cause is unknown.

  • Based on twin studies, 80-90% is based on genetic factors.

  • Fragile X in 8% of autistic males.

  • Increased frequency of pre and perinatal complications

  • Many brain abnormalities



Poor prognosis

  • Poor prognosis

  • No medications—

  • Behavioral tx work best

    • Eliminate self-injurious behavior
    • Social skills training
    • Development of language skills
    • Hard to find reinforcers
    • Don’t like change
    • Self-stimulation interferes with teaching
    • Difficulty generalizing learning
    • Lovaas—highly positive results
      • Intensive, in home
      • 47% achieved normal intellectual functioning


Disorders of receptive and expressive language and reading, writing, mathematics

  • Disorders of receptive and expressive language and reading, writing, mathematics

    • Two groups are highly comorbid
    • All are more common in boys
    • Look for discrepancy between expected and actual achievement
  • Reading disorder

    • Word recognition, reading comprehension
    • Typically spelling too
    • Difficulty with oral reading—either omit or add
    • Phonological awareness!
    • 2-8% of kids (5% sounds about right)
  • Mathematics disorder

    • Difficulty with variety of skills including coding written problems into math symbols; perceptual organization skills like recognizing symbols
    • Less common than reading, maybe 1% of kids
  • Written expression

    • Impairment of ability to write words, spelling, grammar, punctuation, ,handwriting
    • Write less complex and less interesting essays
    • <1% of kids
    • Less research on this


Receptive-expressive language disorder

  • Receptive-expressive language disorder

    • Trouble producing and understanding spoken language
    • Those with receptive may appear deaf
  • Phonological disorder

    • Able to comprehend and use substantial vocabulary, but actual sounds are disturbed.
    • Later acquired speech sounds are more difficult—r, sh, th, f, z, l, ch, j
    • May need speech therapy
    • May recover


Causes

  • Causes

    • Genetically influenced
    • Neurological deficits
  • Treatment

    • Instruction on listening, speaking, reading, and writing skills in a logical, sequential manner.
    • Hands on instruction.
    • Time in seat on task. Not discovery-based.
  • Long term

    • Some deficits continue to adulthood.
    • Lower occupational attainment than would be expected.
    • Cover for deficits by listening to news instead of reading, etc.


Significantly subaverage intellectual functioning

  • Significantly subaverage intellectual functioning

  • Deficits in adaptive functioning

  • Occurring prior to age 18

  • Intelligence testing—2 sds below

    • About 2.5% of population in theory, 5% in practice
  • Adaptive functioning

    • Problem—what is adaptive in some places isn’t in others
  • Time of onset—can’t occur from an accident later in life

  • Dx often in infancy or before birth

  • Mild cases most often dx’d in school—no obvious phys or neuro manifestations

  • Only about 25% have known organic cause.

  • Most mild cases have no known cause



Mild—50/55 to 70 AKA EMI

  • Mild—50/55 to 70 AKA EMI

    • 85% of ID pop
    • By late teens can learn to about 6th grade level
    • Unskilled jobs or sheltered workshops
    • May marry, have kids
    • Often no brain pathology, just kids with parents with low SES, low IQ
  • Moderate—35/40 to 50/55 AKA TMI

    • 10% of ID pop
    • May have phys defects that hinder fine motor skills (pencils) and gross motor (running, climbing) skills
    • Learn to about 2nd grade level
    • Learn some self-care skills
    • Partial independent living—group homes
  • Severe—20/25 to 35/40

    • 3-4% of ID pop
    • Limited sensorimotor control. Some congenital physical abnormalities
    • May be friendly, but can communicate only at a concrete level
  • Profound—IQ below 20/25

    • 1-2% of ID pop
    • Require total supervision and often nursing care
    • High mortality in childhood
    • Can improve skills with training


All ID have deficits to some degree in

  • All ID have deficits to some degree in

    • Communication
    • Academics
    • Sensorimotor skills
    • Self-help
    • Vocational skills
  • Etiology

    • Lack of exposure to reading materials; poor parenting
    • Down syndrome (1/1000 births). Most < 50.
    • PKU 1/14000
    • FAS
    • Infectious diseases (German measles, syphilis) prenatally
    • Prematurity
    • Malnutrition
    • Accidents
    • Radiation in pregnancy
    • Lead poisoning
    • Anoxia


Treatment

  • Treatment

    • Families are satisfied with choice of institutionalization or not
    • Community-oriented care has positives for adolescents
    • Mainstreaming vs. self-contained---
      • Children do well in mainstreaming—modest gains in social skills
      • No particular academic advantage (except for mild MR who may not have rec’d enough attn in self-contained room)
      • Other children are not harmed by ID kids in room


Child’s inability to seek assistance

  • Child’s inability to seek assistance

  • Parental consent is needed except for mature/emancipated minors, emergencies, court order

  • Risk factors for kids

  • Need to address family issues

  • Placement issues

    • Juvenile detention
    • Boot camps
    • Deviancy training


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