Multiscale structures of lipids in foods as parameters affecting fatty acid bioavailability and lipid metabolism



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6. Conclusion
This review highlights the possible impacts on FA intestinal absorption and post-absorptive metabolism of the lipid structures, evaluated at scales ranging from the molecular to the supramolecular ones, including their interactions with the food matrix. These possible nutritional impacts could be now kept in mind in the development of new food formulations with enhanced taste and texture. It remains that the metabolic data obtained in humans are, to date, limited. To improve the level of proof and demonstrate the effects in humans, clinical trials including dietary interventions should now be conducted. These trials will highlight and allow to quantify the potential benefits of the native or recomposed lipid structures. This will allow designing new food formulations with optimized metabolic fate of lipids regarding FA bioavailability and their handling by tissues. Multidisciplinar collaborative projects including specialists of food processing and food science, biochemists, physico-chemists, nutritionists and clinical scientists should now address these challenging issues.

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