Alkaline phosphatase: Alkaline phosphatase values elevated sharply from beginning until day 5th, where the value was 2 folds higher than the normal. After day 5th, a declining trend was observed but normal value could not be restored even till day 30th (Fig. 2).
Fig.2: Alkaline Phosphatase level in liver after 6 Gy of γ-irradiation with
(Experimental) or without (Control) AVE
Glutathione (GSH):
No significant variation was observed in hepatic GSH content of normal (Group-I) and AVE treated animals (Group-II). A dose dependent decrease in GSH content was evident in control animals (Group-III). The decrease in GSH level was more pronounced at the higher dose than at the lower doses of gamma radiation. An increase in GSH value was measured in AVE pretreated irradiated animals i.e. experimental animals.
Blood-GSH:
Blood GSH level also did not show any significant variation in normal (Group-I) and ROE treated animals (Group-II). However, a dose dependent decline was noticed in control animals (Group-III). AVE pretreated irradiated animals (Group-IV) showed a significant increase in GSH level over the control, but the values remained below the normal (Fig. 3).
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