Resume of Soubir Basak

Sankar Bhattacharyya

Tel: [phone]

^Email: [e-mail]

[e-mail]

Date of Birth: 04.09. 1981

Nationality: Indian

14, Ramlal Bazar Row.

Kolkata 700078,

India

.

<sup>OBJECTIVE

Doctorate from Bose Institute, Jadavpur</sup> University^{, India with Post-doctorate experience at} NIH U.S.A as a visiting fellow in the clinical immunology department of NIAID and as a guest scientist at Institute of Pathology, Wuerzburg University, Germany. Working as Assistant Professor , department of Zoology, Sidho Kanho Birsha University, Purulia, West Bengal.


PROFESSIONAL SUMMARY

 Experienced in basic and applied molecular and immunological techniques

 Experienced in Animal cell culture and Tissue preparation

 Experienced with animal model

 Expertise in Immunofluorescence analysis and imaging techniques (confocal and cool CCD imaging)

 Expertise in Flowcytometric techniques

ACADEMIC ACHIEVEMENTS
 Received INSA-DST, INSPIRE faculty award 2012.

 Received Sir Nilratan Sirkar prize 2006 for outstanding research from Bose Institute

 Received First class First Medal from North Bengal University in 2002

 Qualified joint CSIR-UGC Net exam in CSIR-JRF Category

1. Exam held on 23^rd June 2002

2. Exam Held on 22^nd December 2002

3. Exam held on 27^th June 2004

 Qualified GATE 2002 with 83.11 Percentile.

RESEARCH INTEREST

 Role of transcription factors in B cell survival, function and tolerance

 Role of transcription factors and mechanism(s) of germinal centre formation

 Role of B cell –T cell interaction in autoimmune disorders

 Role of B cells in tumor immunology

 Effect of tumor shed soluble factors (such as gangliosides) in immune suppression

Ongoing Project:

“Role of tumor induced inflammatory barrier in tumor establishment”-A DST-INSPIRE faculty award project. (IFA-LSBM-28). INR 35 Lach, 5 years.

ACADEMIC BACKGROUND

 Doctorate 2003-2007

Jadavpur University, India

PhD Thesis: Amelioration of tumor induced immunosuppression by curcumin

M.Sc. Zoology 2000-2002

North Bengal University, India

 B.Sc, Zoology

Calcutta University, India 1997-2000

^{TECHNICAL SKILLS}

 Molecular Techniques: Genomic DNA isolation , RNA isolation and quantification, Restriction digestion,

Gel electrophoresis, PCR, RT PCR, Western blot, Cell culture, Tissue preparation, Plasmid isolation and transfection, siRNA transfection, magnetic bead based cell sorting, In gel enzyme assay.
^{ Immunological Techniques:} Flowcytometry, Co-immunoprecipetations, Chromatin IP

Electrophoretic mobility shift assay, ELISA

RESEARCH EXPERIENCES

Jadavpur University, India 2003-2007

Studied the Amelioration of tumor induced immunosuppression by curcumin

WORK EXPERIENCE 2008-till date

NIH U.S.A Jan’ 08-July’08.

 NIAID/NIH Postdoctoral fellow

Durgapur Govt College, West Bengal, India: Part time faculty Aug’08- June’09.

 Zoology Honors at graduate course

 Conservation biotechnology and genetics at M.Sc conservation biology course

Institute of Pathology, University of Wuerzburg, Germany. July’ 09-July 2011.

 Guest Scientist.

Sidho Kanho Birsha University. Purulia, West Bengal . August’ 12-till date

 Assistant Professor, Department of Zoology

List of Published Papers:

1) Dewan Md Sakib Hossain, Abir K. Panda,Argha Manna,Suchismita Mohanty,Pushpak Bhattacharjee,

Sankar Bhattacharyya, Taniya Saha, Sreeparna Chakraborty, Rajiv K. Kar, Tanya Das, Subhrangsu Chatterjee, and Gaurisankar Sa (2013). FoxP3 Acts as a Cotranscription Factor with STAT3 in Tumor-Induced Regulatory T Cells. Immunity. http://dx.doi.org/10.1016/j.immuni.2013.11.005(Impact factor: 21)

2) Sankar Bhattacharyya (2013). A review on biology and function of regulatory B cells with special reference to inflammation and autoimmune pathogenesis. Proc Zool Soc, DOI: 10.1007/s12595-013-0077-0. (Impact factor: 0.521)

3) Dewan Md Sakib Hossain, Sankar Bhattacharyya, Tanya Das, and Gaurisankar Sa (2012) Curcumin: The multi‐targeted therapy for cancer regression. Frontiers in bioscience (Schol Ed). 2012 Jan 1;4:335-55. (Impact factor: 3.74)

4) Gouri Sankar Sen, Suchismita Mohanty, Dewan Md Sakib Hossain, Sankar Bhattacharyya, Shuvomoy Banerjee, Juni Chakraborty, Shilpi Saha, Pallab Ray, Pushpak Bhattacharjee, Debaprasad Mandal, Arindam Bhattacharya, Samit Chattopadhyay, Tanya Das and Gaurisankar Sa (2011)Curcumin enhances the efficacy of chemotherapy by tailoring p65NF& [kappa]B-p300 cross-talk in favor of p53-p300 in breast cancer. J Biol chem Oct 19. [Epub ahead of print]

(Impact factor: 5.44)
5) Sankar Bhattacharyya, Jolly Deb, Amiya K. Patra, Duong Anh Thuy Pham, Wen Chen, Thomas Benkert, Martin Vaeth, Friederike Berberich-Siebelt, Stefan Klein-Hessling, Edward D. Lamperti, Julia Jellusova, Astrid Schweizer, Lars Nitschke, Ellen Leich, Andreas Rosenwald, Swen Engelmann, Ursula Bommhardt, Andris Avots, Martin R. Müller, Eisaku Kondo^{, §} & Edgar Serfling. (2011) NFATc1 affects mouse splenic B-cell function by controlling the calcineurin-NFAT signalling network, J Exp Med. 208,823-839 (Impact factor: 14.609 Citation :4)
6) Chakraborty J, Banerjee S, Ray P, Hossain DM, Bhattacharyya S, Adhikary A, Chattopadhyay S, Das T, Sa G. (2010) Gain of cellular adaptation due to prolong p53 impairment leads to functional switch-over from p53 to p73 during DNA damage in acute myeloid leukemia cells. J Biol Chem 285, 33104-33112 (Impact factor: 5.44)

7) Bhattacharyya, S., Md Sakib Hossain, D., Mohanty, S., Sankar Sen, G., Chattopadhyay, S., Banerjee, S., Chakraborty, J., Das, K., Sarkar, D., Das, T. and Sa, G. (2010). Curcumin reverses T cell-mediated adaptive immune dysfunctions in tumor-bearing hosts. Cell Mol Immunol 7, 306-315 (Impact factor: 2.765 Citation :5)

8) Chattopadhyay, S., Bhattacharyya, S., Saha, B., Chakraborty, J., Mohanty, S., Sakib Hossain ,DM., Banerjee, S., Das, K., Sa, G. and Das T. (2009). Tumor-shed PGE(2) impairs IL2Rgammac-signaling to inhibit CD4 T cell survival: regulation by theaflavins. PLoS One 8,e7382. (Impact factor: 4.38 Citation :3)
9) Som, M., Kundu, N., Bhattacharyya, S. and Homechaudhuri, S. (2009). Evaluation of haemopoietic responses in Labeo rohita Hamilton following acute copper toxicity. Toxicol Environ Chemistry 91, 87-98 (Impact factor: 0.209)

10) Lahiry, L., Saha, B., Chakraborty, J., Bhattacharyya, S., Chattopadhyay, S., Banerjee, S.,Choudhuri, T., Mandal, D., Bhattacharyya, A., Sa, G. and Das. T. (2008): Contribution of p53-mediated Bax transactivation in theaflavin-induced mammary epithelial carcinoma cell apoptosis. Apoptosis 13,771-781(Impact factor: 3.8, Citation :3)

11) Bhattacharyya, A., Mandal, D., Lahiry, L., Bhattacharyya, S., Chattopadhyay, S., Sa, G. and Das, T. (2007): Black tea-induced hepatic toxicity in tumor bearing animals. JEPTO 26, 245-254 (Impact factor: 1.4. Citation: 1)

12) Mandal, D., Bhattacharyya, S., Lahiry, L., Chattopadhyay, S., Sa, G. and Das, T. (2007): Black tea-induced decrease in IL-10 and TGF-β of tumor cells promotes Th1/Tc1 response in tumor-bearer. Nutrition and Cancer 58,213-221(Impact factor: 2.839)

13) Bhattacharyya, S., Mandal, D., Saha, B., Sen, G.S., Das, T. and Sa, G., (2007): Curcumin protects tumor-induced T cell apoptosis through Stat-5A-mediated Bcl-2 induction. J Biol Chem 282,15954-15964 (Impact factor: 5.44. Citation:38)

14) S., Bhattacharyya, Mandal D., Sen, G. S., Pal, S., Banerjee, S., Lahiry, L., Finke, J. H., Tannenbaum, C.S., Das, T. and Sa, G. (2007): Tumor-induced oxidative stress perturbs NFB activity augmenting TNF-mediated T cell death: Protection by curcumin. Cancer Res 67,362-370 (Impact factor: 8.194. Citation: 32)

15)Aditya, G., Bhattacharyya, S., Kundu, N., Kar, P.K. and Saha, G.K (2007): Predatory efficiency of the sewage drain inhabiting larvae of Toxorhynchites splendens Wiedemann on Culex quinquefasciatus Say and Armigeres subalbatus (Coquillett) larvae. Southeast Asian J Trop Med Public Health 38,799-807

16) Mookerjee, A., Mookerjee Basu, J., Dutta, P., Majumder, S., Bhattacharyya, S., Biswas, J., Pal, S., Mukherjee, P., Raha, S., Baral, R.N., Das, T., Efferth, T., Sa, G., Roy, S. and Choudhuri, S.K. (2006): Overcoming drug-resistant cancer by a newly developed copper chelate through host protective cytokine-mediated apoptosis. Clin Cancer Res 12, 4339-4349 (Impact factor: 6.768. Citation:4)

17) Mandal, D., Lahiry, L., Bhattacharyya, A., Bhattacharyya, S., Sa G, and Das, T. (2006): Tumor-induced thymic involution via inhibition of IL-7R and its JAK-STAT signaling pathway: Protection by Black Tea. International Immunopharmacol 6,433-444 (Impact factor: 2.312)

18) Pal, S., Bhattacharyya, S., Choudhuri, T., Datta, G.K, Das, T. and Sa, G. (2005): Amelioration of immune cell number depletion and potentiation of depressed detoxification system of tumor- bearing mice by curcumin. Cancer Detection and Prevention 2, 9470-9478 (Impact factor: 2.378. Citation:1)

19) Aditya, G., Bhattacharyya, S., Kundu, N. and Saha, G.K. (2005): Frequency-dependent prey-selection of predacious water bugs on Armigeres subalbatus immatures. J Vector Borne Diseases 42,9-14 (Impact factor: 0.65. Citation:1 )

20) Aditya, G., Bhattacharyya, S., Kundu, N., Saha, G.K. and Raut, S.K. (2004)Predatory efficiency of the water bug Sphaerodema annulatum on mosquito larvae (Culex quinquefasciatus) and its effect on the adult emergence. Bioresourse Technol 95,169-172 ( Impact factor : 4.91, Citation:2)