Sectia de stiinte medicale

Prof.Dr.Gheorghe Benga m.coresp.

Nume (cu prenume), titluri:	Profesor Gheorghe Benga, Dr. med., Dr. Honoris Causa (Multiplu), Medic specialist de laborator clinic, medic primar de genetică medicală, chimist, M.c. al Academiei Române, M. Titular al Academiei de Ştiinţe Medicale din România
Ocupaţia (funcţii remunerate)	- Medic primar coordonator, Laboratorul de Explorări Genetice I al Spitalului Clinic Judeţean de Urgenţă Cluj (din 1 oct. 2009) - Profesor asociat, Disciplina de Biologie Celulară şi Moleculară, Universitatea de Vest „Vasile Goldiş” din Arad (din 1 oct. 2010)
Poziţii neremunerate	- Honorary Associate, School of Molecular Biosciences, University of Sydney, Australia - Preşedinte al Filialei Cluj a CRIFST (Comitetul Român pentru Istoria şi Filosofia Ştiinţei şi Tehnicii) (2007-prezent) - Preşedinte al Fundaţiei Gheorghe Benga, al Fundaţiei Benga- Ghilezan şi al Fundaţiei OUTNOBEL
Adresa:	Aleea Muscel nr. 19 ap. 11, 400076 Cluj-Napoca
Telefon:	0264-441725; Fax: [phone]; Email: [e-mail]

2. REALIZĂRI DEOSEBITE în ultimul an:

- Perfecţionarea metodelor de diagnostic al aminoacidopatiilor în laboratorul de

Explorări Genetice I al Spitalului Clinic Judeţean de Urgenţă Cluj

- Medalia de aur „Vasile Goldiş” (acordată de Univ. de Vest „Vasile Goldiş” din Arad cu prilejul aniversării a 95 de ani de la Marea Unire)

3. PUBLICAŢII IN 2013
ARTICOLE ŞTIINŢIFICE PUBLICATE IN REVISTE CU FACTOR DE IMPACT (ISI THOMPSON REUTERS) = 2

1. 
   Gh. Benga: Comparative studies of water permeability of red blood cells from humans and over 30 animal species: an overview of 20 years of collaboration with Philip Kuchel, Eur. Biophys.J., 42, 33- 46, 2013.
   
2. 
   Frenţescu L., Budişan L., Gh. Benga: The profile of cystic fibrosis transmembrane conductance regulator gene mutations in patients from Romania in relationship with the ethnogenesis of the Romanian people, Acta Endocrinologica (Buc), 9(3), 349-360, 2013.
   

ARTICOLE ŞTIINŢIFICE PUBLICATE IN REVISTE ISI (THOMPSON REUTERS) FARA FACTOR DE IMPACT

1. 
   Gh. Benga: Aquaporinology (the study of water channel proteins - aquaporins and relatives) as a new domain of natural sciences, Oltenia. Studii şi comunicări. Ştiinţele Naturii (Oltenia for Studies in natural Sciences), 29 (1), 316-319, 2013.
   

4. IMPACTUL OPEREI STIINŢIFICE (ACTUALIZARE IN 17 DEC 2013)

4.1. CĂRŢI

Synopsis al impactului cărţilor ştiinţifice (WorldCat Identities, 14. FEB 2013)

Ca Editor, am 30 lucrări („works”) în 67 publicaţii (65 în engleză, 2 în română) ce se află în 1714 biblioteci din sistemul WorldCat.

Se mai adaugă 7 cărţi de autor, care nu sunt cuprinse în cele 67 de mai sus.

Benga, Gheorghe (WorldCat Identities, 14.02.2013)

Overview

Works:	30 works in 67 publications in 2 languages and 1,714 library holdings
Roles:	Editor
Classifications:	qh601, 574.875

4.2. ARTICOLE ŞTIINŢIFICE

Synopsis al impactului articolelor ştiinţifice (din ISI WEB OF KNOWLEDGE, în

17.12.2013) Număr de publicaţii: 155 ; Număr total de citări: 1987

Articole care citează (fără autocitări): 1020

Număr mediu de citări per item: 12.7

Index Hirsch : 23

Citări 2013 (pana in 17 dec): 120

Prof.Dr.Cernescu Costin, membru corespondent, Director onorific Institutul de Virusologie
1.The effectiveness of cytological rescreening in the reduction of false negative/positive Pap reports.

Autors: Cernescu EC, Anton G, Ruță S, Cernescu C.

Roum Arch Microbiol Immunol. 2013 Apr-Jun;72(2):93-104. English, Romanian.

PMID: 24187808

2.George Emil Palade centenary (1912-2012): his student years in Bucharest.

Author: Cernescu C.

Roum Arch Microbiol Immunol. 2012 Oct-Dec;71(4):161-4. English, Romanian.

PMID: 23755697

3.Lucrare importanta

Investigation of Th1/Th2 cytokine profiles in patients with laryngo-pharyngeal, HPV-positive cancers.

Eur Arch Otorhinolaryngol. 2013 Feb;270(2):711-8. doi: 10.1007/s00405-012-2067-7. Epub 2012 Jun 13.

Authors: Bleotu C, Chifiriuc MC, Grigore R, Grancea C, Popescu CR, Anton G, Cernescu C.

4.Nobel pentru Medicinã, 2013 – tribut lui George Emil Palade

Autor: Cernescu C.

Academica 2013,23, in press

5.Romanian Scientists in the Nomination Database for the Nobel Prize in Physiology or Medicine, 1901-1951

Proc. Roum Acad. Serie B, 2013, 3, in press

6.Actualitãþi în tratamentul hepatitelor virale

Autori: C. Cernescu și Alexandru Oproiu

Monografie în curs de apariție la Editura Medicală, București

7.Virusologie Medicală – note de curs

Autor: C. Cernescu

Monografie în curs de apariție la Editura Medicală, București
Prof.D.Dobrescu m.coresp.
1. Editura Universitara, in calitate de prim autor , cartea MEMOMED,

editia 19, in doua volume :volumul 1, Memorator de Farmacologie alopata, cu 1118

pagini

2 , Ghid farmacoterapic alopat si homeopat, cu 295 pagini.

Lucrare importanta
3. A obtinut aprobarea si a publicat revista on line FIRST JOURNAL OF HOMEOPATHIC PHARMACOLOGY. Este o premiera in literatura medicala internationala. Scopul revistei este promovarea pe plan mondial, a noii stiinte medicale, Farmacologia homeopata, pe care am fundamentat-o in 2007. Revista apare trimestrial. In 2013 au

aparut primele doua numere, in trimestruele 3 si 4.

Prof. C. Ionescu-Tirgoviste Membru Corespondent
Lucrari publicate sau communicate la congrese internationale in 2012-2013=21

1. 
   Cardwell C.R., L.C.Stene, J.Ludvigsson, J.Rosenbauer,O. CInek, J.Svensson, F.Perez-Bravo, A.Memon, S.G. Gimeno, E.J.K. Wadsworth,E.S.Strotmeyer,M.J. Goldacre,K.Radon,L-M Chuang, R.C. Parslow, A. Chetwynd, K. Karavanaki, G.Brigis, P.Pozzilli, B.Urbonaite, E.Schober, G.Devoti, S.Sipetic,G.Joner, C.Ionescu-Tirgoviste, C.E. de Beaufort, H. Harrild, V. Benson, E.Savilahti, A.-L. Ponsonby, M.Salem, S.Rabiei, C.C. Patterson : Breast-feeding and childhood-onset type 1 diabetes: a pooled analysis of individual participant data from 43 observational studies.Diabetes Care 35:2215-2225, 2012.
   
2. 
   Gagniuc P. A., Ionescu-Tirgoviste C. Eukaryotic genomes may exhibit up to 10 generic classes of gene promoters. BMC Genomics 13:512, 2012.
   
3. 
   Ionescu-Tirgoviste C., Vasilescu R., Timar R., Guja C., Gagniuc P., Bacanu E., Gligor R., Carniciu S. The proinsulin-to-adiponectin ratio could be the best practical indicator of the early (prehyperglycaemic) phase of type 2 diabetes. Adipobiology 4:41-50, 2012.
   
4. 
   Cardwell, CR, Svensson, J, Waldhoer, T, Ludvigsson, J, Sadauskaite-Kuehne, V, Roberts, CL, Parslow, RC, Wadsworth, EJ, Brigis, G, Urbonaite, B, Schober, E, Devoti, G, Ionescu-Tirgoviste, C, de Beaufort, CE, Soltesz, G, Patterson, CC (2012). Interbirth interval is associated with childhood type 1 diabetes risk. Diabetes, 61, 3:702-7.
   
5. 
   Paul A Gagniuc, Constantin Ionescu-Tirgoviste - An evolutionary perspective on adiponectin and insulin gene promoters - Adipobiology; 4 ;2012
   
6. 
   Paul Gagniuc, Paul Dan Cristea, Rodica Tuduce, Constantin Ionescu-Tîrgovişte, Lucian Gavrila, DNA patterns and evolutionary signatures obtained through Kappa Index of Coincidence. Revue Roumaine des Sciences Techniques - Série Électrotechnique et Énergétique, Vol 1, No. 1, 2012.
   
7. 
   Pascu M, Miulescu R, Ionescu-Tîrgoviste C. Fetal Macrosomia in the Diabetic Woman. Rom J. Diabetes Nutr. Metab. Dis 19(1):41-48, 2012
   
8. 
   Caceaune E., Licăroiu D., Brădescu O., Caceaune N., Ionescu-Tîrgovişte C. Metabolic disorders and cardiovascular risk enhanced by nonalcoholic fatty liver disease in patients with metabolic syndrom. Rom J. Diabetes Nutr. Metab. Dis. 19(2):151-160, 2012
   
9. 
   Ionescu-Tirgoviste C. Editorial:Medicine shouldn’t be considered a good business; Rom J. Diabetes Nutr. Metab. Dis. 19(4):337-341, 2012
   
10. 
    Zetu C, Munteanu R, Frunză A, Ionescu-Tîrgovişte C. Update on the Mechanisms Facilitating Weight Loss and Resolution of Type 2 Diabetes Following Bariatric Surgery. Rom J. Diabetes Nutr. Metab. Dis. 19(4):425-432, 2012
    
11. 
    Cristian Guja, Loreta Guja, Paul Gagniuc and Constantin Ionescu-Tîrgovişte, Landscape of monogenic diabetes in the third millennium. Proc. Rom. Acad., Series B, 2013, 15(3), p. 217-232.
    
12. 
    P. Gagniuc and C. Ionescu-Tîrgovişte, Dynamic block allocation for biological sequences. Proc. Rom. Acad., Series B, 2013, 15(3), p. 234-240.
    
13. 
    S. Pruna, A. Bealle and C. Ionescu-Tîrgovişte, Health data analysis: measuring outcomes and quality of diabetes care in the Black Sea region. Proc. Rom. Acad., Series B, 2013, 15(3), p. 251-263
    
14. 
    S. PRUNA, C. PURTILL, M. MASSI BENEDETTI, F. CARINCI, C. DI IORIO, P. BECK, S. CUNNINGHAM, S. SKEIE, J. AZZOPARDI, V. TRAYNOR AND C. IONESCU-TIRGOVISTE. Screening for diabetic hypertension in newly diagnosed Type 2 diabetes using a new technology that carries out in minutes agregated data analysis. Proc. Rom. Acad., Series B, 2013, 15(2), p. 87-98.
    
15. 
    Eliza Gangone, Dragos Romanescu, Mihaela Chivu-Economescu, Coralia Bleotu, Dana Tomescu, Simona Carniciu, Cristian Guja, Simona Dima, Constantin Ionescu-Tirgoviste and Irinel Popescu, Total pancreatectomy with autologus islet cells transplantation, Proc. Rom. Acad., Series B, 2013, 15(1), p. 7-13
    
16. 
    Rucsandra Dănciulescu Miulescu, Suzana Dănoiu, Denisa Margină, Cătălina Poiană and Constantin Ionescu-Tirgovişte, The prevalence of anaemia in patients with type 2 diabetes mellitus and low testosterone, Proc. Rom. Acad., Series B, 2013, 15(1), p. 34-37
    
17. 
    Ionescu-Tirgoviste C. Regarding the Classification, Prediction and Prevention of Diabetes; Rom J. Diabetes Nutr. Metab. Dis. 20(3):251-258, 2013
    
18. 
    Guja C. Guja L. Ionescu-Tîrgovişte C. Neonatal Diabetes – From Gene Discovery yo Clinical Practice Changes; Rom J. Diabetes Nutr. Metab. Dis. 20(3):343-352, 2013
    
19. 
    C. Zetu, R. Munteanu , R. Parasca , C. Ionescu-Tîrgovişte. Nutritional Deficiencies Associated to Bariatric Surgery; Rom J. Diabetes Nutr. Metab. Dis. 20(2):157-164, 2013
    
20. 
    Caceaune Elena, Lixandru Daniela, Copaci Ionel, Caceaune Nicu, Constantin Ionescu-Tirgoviste - Proinsulin and adiponectin in patients with nonalcoholic fatty liver disease, Farmacia, vol 6/2013
    
21. 
    Paul A Gagniuc, Constantin Ionescu-Tirgoviste - Gene promoters show chromosone-specificity and several chromosone territories in humans, BMC Genomics, vol 14, 278-290; 2013
    

In tara = 8
1. Roşca A, Carniciu S, Petcu L, Mitu M, Lixandru D, Stoian I., Ionescu-Tirgovişte C - Insulin resistance indexes associate with TG/HDL_c in newly diagnosed type 2 diabetes mellitus patients - Congresul Anual al Asociaţiei Medicale Române – 31mai – 2 iunie 2013, Bucuresti

2. Alexandru Petruţa, Lixandru Daniela, Stoian Irina, Ionescu-Tîrgovişte Constantin, Petrescu M Ştefana - The role of paraoxonase 2 in insulin synthesis and secretion The 39th National Congress of the Romanian Society of Diabetes, Nutrition and Metabolic Diseases with international participation, Sibiu, Romania 22-25 Mai 2013, Abstract publicat în Acta Diabetologica Română, vol 39, ISSN 1584-6571

3. Carniciu Simona, Licaroiu Daniela, Caceaone Elena, Lixandru Daniela, Mihai Andrada, Ionescu-Tîrgovişte Constantin – The cardiovascular risk in newly discovered diabetic patients using TG/HDL-c ratio The 39th National Congress of the Romanian Society of Diabetes, Nutrition and Metabolic Diseases with international participation, Sibiu, Romania 22-25 Mai 2013, Abstract publicat în Acta Diabetologica Română, vol 39, ISSN 1584-6571

4. Lixandru Daniela, Stoian Irina, Roşca Adelina, Cristescu Cristina, Ursache Mihaela, Carniciu Simona, Copaescu Cătălin, Ionescu-Tîrgovişte Constantin – The relationship between obesity and type 2 diabetes – the role of paraoxonase 2 - 5^th International Congress on Prediabetes and the metabolic syndrome, PDMS Viena, Austria, 18-20 Aprilie 2013, Abstract publicat în Journal of Diabetes vol 5 (Supplement 1), ISSN 1753-0393

5. Picu Ariana, Petcu Laura, Lixandru Daniela, Stoian Irina, Cristescu Cristina, Rusu Elena, Ionescu-Tirgoviste Constantin – Involvement of the oxidative stress associated obesity in newly-diagnosed type 2 diabetes - 5^th International Congress on Prediabetes and the metabolic syndrome, PDMS Vienna, Austria, 18-20 Aprilie 2013, Abstract publicat în Journal of Diabetes vol 5 (Supplement 1), ISSN 1753-0393

6. C. Ionescu-Tirgoviste, P. Gagniuc, C. Guja – The promoters of genes associated with type 1 and type 2 diabetes seem to have some specific features – 48^th EASD Annual Meeting , 1-5 October, Berlin, Abstract publicat in Diabetologia, vol 55, Supplement 1, 2012

1. Lixandru Daniela, Carniciu Simona, Roşca Adelina, Stoian Irina, Atanasiu Valeriu, Ionescu-Tîrgovişte Constantin - Adipocytokines and paraoxonases: their significance in obese newly-diagnosed type 2 diabetes patients - Congresul Anual al Asociaţiei Medicale Române – 31mai – 2 iunie 2013, Bucuresti

2. Lixandru Daniela, Carniciu Simona, Roşca Adelina, Stoian Irina, Atanasiu Valeriu, Cristescu Vasilică, Ionescu-Tîrgovişte Constantin - The influence of adipokines on the paraoxonase 1 and 2 enzymatic activities in newly discovered type 2 diabetic patients – The 39th National Congress of the Romanian Society of Diabetes, Nutrition and Metabolic Diseases with international participation, Sibiu, Romania 22-25 Mai 2013, Abstract publicat în Acta Diabetologica Română, vol 39, ISSN 1584-6571

3. Lixandru Daniela, Alexandru Petruţa, Roşca Adelina, Stoian Irina, Copaescu Cătălin, Ionescu-Tîrgovişte Constantin, Petrescu M. Ştefana - “The relationship between β-pancreatic cells and adipocytes – the study of paraoxonase 2” - The Annual International Conference of the Romanian Society of Biochemistry and Molecular Biology (RSBMB) & The Conference on Cellular and Molecular Biotechnologies on Medical Applications”, 13-14 septembrie, Bucureşti – Abstract publicat in Romanian Journal of Biochemistry, vol. 49, Supplementa, 2012

Monografii:

Ionescu-Tirgoviste C. - Istoria neuropatiei diabetice in Romania,

Soc Romana de Neuropatie Diabetica

ISBN 978-973-0-15565-5

Bucuresti 2013
Prof.Dr. Leonida Gherasim m.o.

• 
  Publicatii-teme stiintifice =4
  

4 articole in Rev.Roum. Med.Interne

• 
  Ghid national de profilaxie a tromboembolismului venos (Ed.III)
  

Academica – articol comemorare Prof.I.Bruckner.
Conferinte la Academia Romana = 2

Aniversarea a 100 ani nasterea acad.Marin Voiculescu

Aniversarea a 75 ani de la infiintarea Spitalului Elias si 10 ani de spital universitar.
Participari la Congrese si Conferinte= 4
1.Congresul National de Medicina Interna

2. Congresul National de Cardiologie

3. Conferinta Grupurilor de lucru ale Societatii Romane de Cardiologie

4. Conferinta “Medicina bazata pe dovezi” a Societatii Romane de Medicina Interna.

Activitati speciale = 2
Presedinte al Consiliului stiintific al Agentiei nationale a medicamentului

Membru al Comitetului Director: Consiliul de Acreditare al Spitalelor.

Prof.Dr.Irinel Popescu m.coresp., medic primar chirurgie, Boli Digestive si transplant. Prof.Univ.UMF Carol Davila
ISI/2013 = 17

1. 
   Dynamics of the Romanian waiting list for liver transplantation after changing organ allocation policy.
   

Gheorghe L, Iacob S, Iacob R, Smira G, Pietrareanu C, Hrehoret D, Brasoveanu V, Gheorghe C, Popescu I.

J Gastrointestin Liver Dis. 2013 Sep;22(3):299-303.

2. 
   Assessment of the stromal contribution to Sonic Hedgehog-dependent pancreatic adenocarcinoma.
   

Damhofer H, Medema JP, Veenstra VL, Badea L, Popescu I, Roelink H, Bijlsma MF.

Mol Oncol. 2013 Aug 16. doi:pii: S1574-7891(13)00115-4. 0.1016/j.molonc.2013.08.004. PMID:23998958[PubMed - as supplied by publisher]

3. 
   PMID:24078987[PubMed - in process]Reply to Letter: Whether the Extent of Fat Dissection Is Correlated With Complete Stable Remission of Myasthenia Gravis?
   

Tomulescu V, Valciu C, Herlea V, Popescu I.

Ann Surg. 2013 Feb 19. [Epub ahead of print] No abstract available.

PMID: 23426351

4. 
   Prevalence of Nonalcoholic Steatohepatitis Among Patients with Resectable Intrahepatic Cholangiocarcinoma.
   

Reddy SK, Hyder O, Marsh JW, Sotiropoulos GC, Paul A, Alexandrescu S, Marques H, Pulitano C, Barroso E, Aldrighetti L, Geller DA, Sempoux C, Herlea V, Popescu I, Anders R, Rubbia-Brandt L, Gigot JF, Mentha G, Pawlik TM.

J Gastrointest Surg. 2013 Jan 25. [Epub ahead of print]; PMID: 23355033

5. 
   Comparative study of the efficacy and safety of ceftazidime/avibactam plus metronidazole versus meropenem in the treatment of complicated intra-abdominal infections in hospitalized adults: results of a randomized, double-blind, Phase II trial.
   

Lucasti C, Popescu I, Ramesh MK, Lipka J, Sable C.

J Antimicrob Chemother. 2013 Feb 7. [Epub ahead of print]

PMID: 23391714 [PubMed - as supplied by publisher]

Metastatic colorectal cancer--what about the primary?

6. 
   Popescu I, Alexandrescu ST.
   

Acta Chir Iugosl. 2013; 59(2):47-55.

PMID: 23373358 [PubMed - in process]

7. 
   Resection for Hilar Cholangiocarcinoma: Analysis of Prognostic Factors and the Impact of Systemic Inflammation on Long-term Outcome.
   

Dumitrascu T, Chirita D, Ionescu M, Popescu I.

J Gastrointest Surg. 2013 Jan 15. [Epub ahead of print]

PMID: 23319395, [PubMed - as supplied by publisher]

8.Distinct Mutational Patterns of Infection and Non-Infection-Related Bile Duct Cancers Revealed by Exome Sequencing

Waraporn Chan-on^1,2,3*, Maarja-Liisa Nairismägi^1,2*, Choon Kiat Ong^1,2*, Simona Dima⁴, Chawalit Pairojkul³, Kiat Hon Lim5, John R. McPherson6, Weng Khong Lim^1,2, Ioana Cutcutache⁶, Hong Lee Heng^1,2, London Ooi⁷, Alexander Chung⁷, Pierce Chow⁷, Peng Chung Cheow⁷, Lee Ser Yee⁷, Iain Tan Bee Huat8, Dan Duda⁹, Anca Nastase⁴, Swe Swe Myint^1,2, Bernice Huimin Wong^1,2, Anna Gan^1,2, Vikneswari Rajasegaran^1,2, Cedric Chuan Young Ng1,2, Apinya Jusakul ^1,2,Shenli Zhang2, Priya Vohra2, Willie Yu^1,2,10, DaChuan Huang^1,2, Puangrat Yongvanit3, Sopit Wongkham3, Narong Khuntikeo3, Vajaraphongsa Bhudhisawasdi3, Irinel Popescu4,#, Steven G. Rozen6,#, Patrick Tan2^,11,12,#, Bin Tean Teh1^,2,12,#

Nature Genetics 2013

IF: 35.209 ( in press)

9.Exome Sequencing Reveals Frequent Inactivating Mutations in Chromatin Remodeling Genes in Intrahepatic Cholangiocarcinomas

Yuchen Jiao¹*, Timothy M. Pawlik²*, Robert A. Anders³*, Florin M. Selaru⁴, Mirte M. Streppel³, Donald J. Lucas⁵, Noushin Niknafs⁶, Violeta Beleva Guthrie⁶, Anirban Maitra³, Pedram Argani³, G. Johan A. Offerhaus⁷, Juan Carlos Roa⁸, Lewis R. Roberts⁹, Gregory J. Gores⁹, Irinel Popescu¹⁰, Sorin T. Alexandrescu¹⁰, Simona Dima¹⁰, Matteo Fassan^11,12, Michele Simbolo^11,12, Andrea Mafficini¹¹, Paola Capelli¹², Rita T. Lawlor¹¹, Andrea Ruzzenente¹³, Alfredo Guglielmi¹³, Giampaolo Tortora¹⁴, Filippo de Braud¹⁵, Aldo Scarpa^11,12+, William Jarnagin¹⁶, David Klimstra¹⁷, Rachel Karchin⁶, Victor E. Velculescu¹, Ralph H. Hruban³, Bert Vogelstein¹, Kenneth W. Kinzler¹+, Nickolas Papadopoulos¹+, and Laura D. Wood³+

Nature Genetics 2013

IF: 35.209 ( in press)

10.Dynamics of the Romanian waiting list for liver transplantation after changing organ allocation policy.

Gheorghe L, Iacob S, Iacob R, Smira G, Pietrareanu C, Hrehoret D, Brasoveanu V, Gheorghe C, Popescu I.

J Gastrointestin Liver Dis. 2013 Sep;22(3):299-303.

11.Reply to Letter: "Is the Extent of Fat Dissection Correlated With Complete Stable Remission of Myasthenia Gravis?"

Tomulescu V, Valciu C, Herlea V, Popescu I.

ANNALS OF SURGERY Volume: 257 Issue: 4 Pages: E11-E12 DOI: 10.1097/SLA.0b013e3182891e68 Published: APR 2013

Times Cited: 0, IF: 6.329

12.Title: Resection for Hilar Cholangiocarcinoma: Analysis of Prognostic Factors and the Impact of Systemic Inflammation on Long-term Outcome

Dumitrascu T, Chirita D, Ionescu M., Popescu I.

JOURNAL OF GASTROINTESTINAL SURGERY Volume: 17 Issue: 5 Pages: 913-924 DOI: 10.1007/s11605-013-2144-2 Published: MAY 2013

Times Cited: 0 , IF: 2.361

13. Translational research: Scientometric evaluation of the Center of General Surgery and Liver Transplantation Fundeni)Irinel Popescu, Simona Dima; Rev.Pol.St.&Scientometrie,vol.2,no.3,2013,197-208.

14.Dynamics of the Romanian waiting list for liver transplantation after changing organ allocation policy.

Gheorghe L, Iacob S, Iacob R, Smira G, Pietrareanu C, Hrehoret D, Brasoveanu V, Gheorghe C, Popescu I.

J Gastrointestin Liver Dis. 2013 Sep;22(3):299-303.

Times Cited: 0, IF: 1.855

15.Reply to Letter: "Is the Extent of Fat Dissection Correlated With Complete Stable Remission of Myasthenia Gravis?"

Tomulescu V, Valciu C, Herlea V, Popescu I.

ANNALS OF SURGERY Volume: 257 Issue: 4 Pages: E11-E12 DOI: 10.1097/SLA.0b013e3182891e68 Published: APR 2013

Times Cited: 0, IF: 6.329
16.Resection for Hilar Cholangiocarcinoma: Analysis of Prognostic Factors and the Impact of Systemic Inflammation on Long-term Outcome

Dumitrascu T, Chirita D, Ionescu M., Popescu I.

JOURNAL OF GASTROINTESTINAL SURGERY Volume: 17 Issue: 5 Pages: 913-924 DOI: 10.1007/s11605-013-2144-2 Published: MAY 2013

Times Cited: 0 , IF: 2.361

17.Title: Comparative study of the efficacy and safety of ceftazidime/avibactam plus metronidazole versus meropenem in the treatment of complicated intra-abdominal infections in hospitalized adults: results of a randomized, double-blind, Phase II trial

Lucasti C, Popescu I, Ramesh M K.; et al.

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY Volume: 68 Issue: 5 Pages: 1183-1192 DOI: 10.1093/jac/dks523 Published: MAY 2013

Times Cited: 0 , IF: 5.330

Carti/ Capitole de carte = 5

1. POPESCU, I.- Central pancreatectomy. Atlas of Advanced Operative Surgery.

Khatri V et al. eds. Elsevier Science. 2013

2. POPESCU, I.- Appleby procedure. Atlas of Advanced Operative Surgery.

Khatri V et al. eds. Elsevier Science. 2013

3.Chapters: in Book "Liver Transplantation / Book 2", ISBN 979-953-307-689-7.

 "Experimental liver transplantation". Edited by: Hesham Abdeldayem and Naglaa Allam
Publisher: InTech, February 2013. Authors: Mirela Patricia Sirbu Boeti, Sadiq
Shoaib, Alaa Elshorbagy, Catalin Iulian Efrimescu, Irinel Popescu

4.  "Arterial anastomosis in living donor liver transplantation".  "Experimental liver transplantation". ISBN 978-953-51-0015-7. http://www.intechopen.com/articles/show/title/arterial-anastomosis-in-living-donor-liver-transplantation. Edited by: Hesham Abdeldayem and Naglaa Allam

Publisher: InTech, February 2013. Authors: Mirela Patricia Sirbu Boeti, Vladislav Brasoveanu, Sadiq Shoaib, Irinel Popescu

5. Chapter: in Pancreatic Cancer / Book (in press)

ISBN 978-953-307-815-1, edited by: Prof. Sanjay K. Srivastava, Ph.D. Associate
Professor, Department of Biomedical Sciences, Texas Tech University Health Sciences
Center, USA
-Novel biomarkers in pancreatic cancer

Lucrari importante aparute in Nature Genetics :2

1. 
   Distinct Mutational Patterns of Infection and Non-Infection-Related Bile Duct Cancers Revealed by Exome Sequencing
   

Waraporn Chan-on^1,2,3*, Maarja-Liisa Nairismägi^1,2*, Choon Kiat Ong^1,2*, Simona Dima⁴, Chawalit Pairojkul³, Kiat Hon Lim5, John R. McPherson6, Weng Khong Lim^1,2, Ioana Cutcutache⁶, Hong Lee Heng^1,2, London Ooi⁷, Alexander Chung⁷, Pierce Chow⁷, Peng Chung Cheow⁷, Lee Ser Yee⁷, Iain Tan Bee Huat8, Dan Duda⁹, Anca Nastase⁴, Swe Swe Myint^1,2, Bernice Huimin Wong^1,2, Anna Gan^1,2, Vikneswari Rajasegaran^1,2, Cedric Chuan Young Ng1,2, Apinya Jusakul ^1,2,Shenli Zhang2, Priya Vohra2, Willie Yu^1,2,10, DaChuan Huang^1,2, Puangrat Yongvanit3, Sopit Wongkham3, Narong Khuntikeo3, Vajaraphongsa Bhudhisawasdi3, Irinel Popescu4,#, Steven G. Rozen6,#, Patrick Tan2^,11,12,#, Bin Tean Teh1^,2,12,#

#Co-corresponding authors

Nature Genetics 2013 , IF: 35.209, 45, 1474-1478.

2. 
   Exome Sequencing Reveals Frequent Inactivating Mutations in Chromatin Remodeling Genes in Intrahepatic Cholangiocarcinomas
   

Yuchen Jiao¹*, Timothy M. Pawlik²*, Robert A. Anders³*, Florin M. Selaru⁴, Mirte M. Streppel³, Donald J. Lucas⁵, Noushin Niknafs⁶, Violeta Beleva Guthrie⁶, Anirban Maitra³, Pedram Argani³, G. Johan A. Offerhaus⁷, Juan Carlos Roa⁸, Lewis R. Roberts⁹, Gregory J. Gores⁹, Irinel Popescu¹⁰, Sorin T. Alexandrescu¹⁰, Simona Dima¹⁰, Matteo Fassan^11,12, Michele Simbolo^11,12, Andrea Mafficini¹¹, Paola Capelli¹², Rita T. Lawlor¹¹, Andrea Ruzzenente¹³, Alfredo Guglielmi¹³, Giampaolo Tortora¹⁴, Filippo de Braud¹⁵, Aldo Scarpa^11,12+, William Jarnagin¹⁶, David Klimstra¹⁷, Rachel Karchin⁶, Victor E. Velculescu¹, Ralph H. Hruban³, Bert Vogelstein¹, Kenneth W. Kinzler¹+, Nickolas Papadopoulos¹+, and Laura D. Wood³+

Nature Genetics 2013,45, 1470-1473.

IF: 35.209
Distinctii 2013
Membru corespondent strain al Academiei Franceze de Medicina

Membru corespondent al Academiei Romane

Prof. Dr. Carol Stanciu m.o. (coordonator CCB-Iasi)

Listă articole in extenso ISI = 8

1. 
   Achitei D, Ciobica A, Balan G, Gologan E, Stanciu C, Stefanescu G, Different profile of peripheral antioxidant enzymes and lipid peroxidation in active and non-active inflammatory bowel disease patients, Dig Dis Sci. 2013 May;58(5):1244-9. doi: 10.1007/s10620-012-2510-z. IF 2012 2.26.
   
2. 
   Irimia R, A. Ciobica, C. Stanciu, A. Trifan, The relevance of oxidative stress in cirrhotic patients with different forms of hepatic encephalopathy, Arch. Biol. Sci., Belgrade, 2013, 65(3), 1245-1252. IF 2012 0,791.
   
3. 
   Trifan A, Chiriac S, Stanciu C., Update on adrenal insufficiency in patients with liver cirrhosis, World J Gastroenterol. 2013 Jan 28;19(4):445-56. doi: 10.3748/wjg.v19.i4.445. IF 2012  2.547
   
4. 
   Razvana Sorina Munteanu Danulescu, Ciobica Alin, Stanciu Carol, Trifan Anca, Studying the levels of glutathione peroxidase in patients with spontaneous bacterial peritonitis, Arch. Biol. Sci., Belgrade, 2013, 65(4), 1593-1597. IF 2012 0,791.
   
5. 
   Stanciu C, Trifan A, Cojocariu C, Capsule endoscopy in acute upper gastrointestinal bleeding: goodbye to nasogastric tube aspiration? Endoscopy. 2013 Sep;45(9):775. doi: 10.1055/s-0033-1344148. IF 2012 5.735.
   
6. 
   Irimia R, Stanciu C, Cojocariu C, Sfarti C, Trifan A., Oral glutamine challenge improves the performance of psychometric tests for the diagnosis of minimal hepatic encephalopathy in patients with liver cirrhosis, J Gastrointestin Liver Dis. 2013 Sep;22(3):277-81. IF 2012 1.855.
   
7. 
   Razvana Sorina Munteanu Danulescu, Ciobica Alin, Stanciu Carol, Singeap Ana Maria, Raluca Iorga, Trifan Anca, The relevance of the oxidative stress balance (superoxide dismutase versus malondiadehyde) in spontaneous bacterial peritonitis, Arch. Biol. Sci., Belgrade, 2014, 66(2). IF 2012 0,791.
   
8. 
   Trifan A, Girleanu I, Cojocariu C, Sfarti C, Singeap AM, Dorobat C, Grigore L, Stanciu C., Pseudomembranous colitis associated with a triple therapy for Helicobacter pylori eradication, World J Gastroenterol. 2013 Nov 14;19(42):7476-9. doi: 10.3748/wjg.v19.i42.7476. IF 2012  2.547
   

BDI: 2

1. 
   Răzvana Munteanu Dănulescu, A. Ciobică, Carol Stanciu, Anca Trifan, The role of rifaximine in the prevention of the spontaneous bacterial peritonitis. Rev. Med. Chir. Soc. Med., 2013, 117(2), 315-320.
   
2. 
   Răzvana Munteanu Dănulescu, A Ciobică, C Stanciu, Anca Trifan, The influence of antibiotic treatment on the dynamics of oxidative stress in spontaneous bacterial peritonitis, Rev. Med. Chir. Soc. Med., 2013, 117(3), 598-604.
   

Rezumate la conferinte (indexate ISI)= 5

1. Title: EFFICACY OF SEQUENTIAL THERAPY AND CVADRUPLE THERAPY AS FIRST-LINE REGIMENS IN HELICOBACTER PYLORI ERADICATION

Author(s): Singeap, A Trifan, A; Cojocariu, C; Girleanu, I Sfarti, C; Stanciu, C.

Conference: 26th International Workshop on Helicobacter and Related Bacteria in Chronic Digestive Inflammation and Gastric Cancer Location: Madrid, SPAIN Date: SEP 12-14, 2013

Sponsor(s): European Helicobacter Study Grp

Source: HELICOBACTER Volume: 18 Special Issue: SI Supplement: 1 Pages: 140-140 Published: SEP 2013

2. Title: PREDICTING FACTORS FOR HELICOBACTER PYLORI ERADICATION FAILURE IN STANDARD TRIPLE THERAPY

Author(s): Singeap, A.; Trifan, A.; Cojocariu, C.; Girleanu, I Sfarti, C; Stanciu, C.

Conference: 26th International Workshop on Helicobacter and Related Bacteria in Chronic Digestive Inflammation and Gastric Cancer Location: Madrid, SPAIN Date: SEP 12-14, 2013

Sponsor(s): European Helicobacter Study Grp

Source: HELICOBACTER Volume: 18 Special Issue: SI Supplement: 1 Pages: 142-142 Published: SEP 2013

3. ALISPORIVIR (ALV) PLUS PEGINTERFERON/RIBAVIRIN (PR) ACHIEVES HIGH SVR12 RATES AMONG NULL RESPONDERS, IL28BCT/TT AND CIRRHOTIC HCVG1 PATIENTS (FUNDAMENTAL STUDY INTERIM ANALYSIS)

Author(s): Buti, M.; Flisiak, R.; Rasenack, J.; Davis, G; Alberti, A; Goeser, T, Stanciu, C Chuang, WL; Tabak, F ; Kao, JH; Streinu-Cercel, A Hofstetter, G Wang, J Avila, C; Orsenigo, R

Conference: International Liver Congress / 48th Annual Meeting of the European-Association-for-the-Study-of-the-Liver (EASL) Location: Amsterdam, NETHERLANDS Date: APR 24-28, 2013

Sponsor(s): European Assoc Study Liver (EASL)

Source: JOURNAL OF HEPATOLOGY Volume: 58 Supplement: 1 Pages: S572-S572 Meeting Abstract: 1421 Published: APR 2013
4. ORAL GLUTAMINE CHALLENGE - DOES IT IMPROVE REVEALING MINIMAL HEPATIC ENCEPHALOPATHY IN CIRRHOSIS?

Author(s): Irimia, R.; Cojocariu, C.; Sfarti, C.; Stanciu, C ; Trifan, A.;

Conference: International Liver Congress / 48th Annual Meeting of the European-Association-for-the-Study-of-the-Liver (EASL) Location: Amsterdam, NETHERLANDS Date: APR 24-28, 2013

Sponsor(s): European Assoc Study Liver (EASL)

Source: JOURNAL OF HEPATOLOGY Volume: 58 Supplement: 1 Pages: S89-S89 Meeting Abstract: 203 Published: APR 2013
5. PHASE II HCVac STUDY OF TG4040 IMMUNOTHERAPEUTIC IN COMBINATION WITH PEGIFN alpha 2a AND RIBAVIRIN IN GENOTYPE 1 CHC TREATMENT NAIVE PATIENTS: SVR24 FINAL RESULTS

Author(s): Wedemeyer, H.; Kazek, E. Janczewska; Wlodzimierz, M.; Stanciu, C; Habersetzer, F Carreno, V; Di Bisceglie, A Tanasescu, C; Flisiak, R; Romero-Gomez, M Fich, A; Hennequi, M ; Bain, C; Zerr, P; Agathon, D; Adda, N; Bonnefoy, JY; Inchauspe, G (; Ancian, P (; Limacher, JM.

Conference: International Liver Congress / 48th Annual Meeting of the European-Association-for-the-Study-of-the-Liver (EASL) Location: Amsterdam, NETHERLANDS Date: APR 24-28, 2013

Sponsor(s): European Assoc Study Liver (EASL)

Source: JOURNAL OF HEPATOLOGY Volume: 58 Supplement: 1 Pages: S28-S28 Meeting Abstract: 62 Published: APR 2013
Listă cărţi
1. Carol Stanciu, Gheorghe Balan, C. Prelipcean, Anca Trifan, Curs intensive de boli digestive, 2013, Editura “Gr. T. Popa”, format academic, 560 pag.
Capitole cărţi = 6
1. Camelia Cojocaru, Anca Trifan, Sidonia Bucătaru, Alina Andriucă, Carol Stanciu. Hemoragia digestivă superioară de cauză variceală. În Curs intensivde boli digestive, Ed. Universităţii de Medicină şi Farmacie „Gr. T. Popa” Iaşi, 2013: 179-191, ISBN
2. Roxana Irimia, Camelia Cojocaru, Catalin Sfarti, Mihaela Dimache, Anca Trifan, Carol Stanciu. Encefalopatia hepatica minima. În Curs intesiv de boli digestive, Ed. Universităţii de Medicină şi Farmacie „Gr. T. Popa” Iaşi, 2013: 202-229, ISBN
3. Răzvana Dănulescu-Munteanu, Camelia Cojocariu, Carol Stanciu, Anca Trifan. Peritonita bacteriană spontană. În Curs intensiv de boli digestive, Ed. Universităţii de Medicină şi Farmacie „Gr. T. Popa” Iaşi, 2013: 230-254, ISBN
4. Irina Gîrlenu, Camelia Cojocariu, Carol Stanciu, Anca Trifan. Tratamentul anticoagulant în tromboza de venă portă la pacienţii cirotici - o nouă paradigmă. În Curs intensiv de boli digestive, Ed. Universităţii de Medicină şi Farmacie „Gr. T. Popa” Iaşi, 2013: 293-308, ISBN
5. Sînzian Preda, Anca Trifan, Cătălin Sfarti, Carol Stanciu, Camelia Cojocariu. Infecţiile bacteriene în ciroza hepatică. În Curs intensiv de boli digestive, Ed. Universităţii de Medicină şi Farmacie „Gr. T. Popa” Iaşi, 2013: 274-292, ISBN
6. Ana-Maria Sîngeap, Anca Trifan, Camelia Cojocariu, Irina Gîrleanu, Cătalin Sfarti, Carol Stanciu. Actualităţi în managementul infecţiei cu Helicobacter pyloric. . În Curs intensiv de boli digestive, Ed. Universităţii de Medicină şi Farmacie „Gr. T. Popa” Iaşi, 2013:579-584, ISBN