Sequential drug decision problems in long-term medical conditions: a case Study of Primary Hypertension Eunju Kim ba, ma, msc

Participants	Persons free of CVD and cancer.	Persons free of CVD and cancer.
Patients aged 35-74, free of CVDs
Statistical model	A non-proportional hazards Weibull accelerated failure time model.	Cox proportional hazards model.	Cox proportional hazards model.
Risk factors included	Age, gender, SBP (or DBP), smoking, TC, HDL, DM and ECG-LVH.	Age, gender, TC, HDL, SBP, smoking and DM.	Ethnicity, age, gender, smoking, SBP, TC/HDL, BMI, family history of CHD, Townsend deprivation score, treated hypertension, type 2-DM, CRD, AF and RA.
Main outcomes	CHD, MI, CHD death, stroke, CVD and CVD death.	CVD, CHD, stroke, CHF and intermittent claudication.	First (incident) diagnosis of CVD (including CHD, stroke, and transient ischemic attack).
Definition of CVD	(Silent and unrecognised) MI, (sudden or non-sudden) CHD death, angina pectoris, coronary insufficiency, stroke including transient ischemia, congestive HF and peripheral vascular disease.	CHD (including coronary death, MI, coronary insufficiency and angina), cerebrovascular events (including ischemic stroke, haemorrhagic stroke, and transient ischemic attack), peripheral artery disease (intermittent claudication) and HF.	CHD (angina and MI), stroke or transient ischaemic attacks.