Solutions for Fatigue and Chronic Fatigue Syndrome There's something in this report for everyone

Mycoplasma Triggering Mechanisms

Mycoplasma is activated and stimulated by initiators (ignition) and potentiators (promoters). The potentiators are the toxic substances in our food, beverages, environment, pharmaceuticals, heavy metals (Mycoplasma amalgams) and chemicals that we bath in, etc. that store in fat cells and weaken our cellular terrain and immune system to allow the initiators (i.e. stress, viruses, bacteria, fungus, parasites, emotional and physical trauma, fear, increased estrogen, anger, etc.) to ignite or light up the gasoline that's poured on the barn -Mycoplasma.

If the gray matter of the brain tissue is the target of Mycoplasma invasion, you'll portray symptoms of dementia, Alzheimer's, Parkinson's, Creutzfeldt-Jakob disease or memory and cognitive thinking disturbances depending on the area of the brain terrorized.

If the spinal cord is the victim, you will exhibit symptoms of neurodegenerative diseases like myasthenia gravis, Guillain-BarrÈ and ALS (Lou Gehrig's disease). If your weakness happens to be the synovial fluid cells in your joints, rheumatoid arthritis with severe joint pain will be your disease. In fact, many of the 21st century diseases that were thought to be autoimmune turned out to be Mycoplasma invasions.

If Mycoplasma invades the beta cells in the pancreas that manufactures insulin, you can't regulate blood sugar and Diabetes Mellitus will be your demise. If your cardiac tissues are your weak link, cardiomy-opathy will manifest. If M. Pneumoniae or M. Fermentans attacks the bronchial lining of the bronchial tubes, the inflammation will trigger asthma and upper respiratory infections. If the myelin sheaths of the nerves are targeted, you will exhibit neurological symptoms of multiple sclerosis. If the intestinal lining is penetrated, the damage to the mucosal lining will perpetrate Crohn's disease or leaky gut. In the case of Lou Gehrig's disease, 80% of the patients have detected at least two Mycoplasma strains -M. Penetrans and M. Fermentans.

In ALS, the oligodendritic nerve cells which require cholesterol to synthesize neurosteroids are eaten. If Mycoplasma population is large enough, they gobble up so much cholesterol they diminish neurosteroid synthesis which leads to severe central nervous system malfunctions. Even Lymes disease, which is the fastest growing infectious disease in the U.S. and possibly Europe, with the exception of AIDS, was found to be linked to both Borrellia and Mycoplasma infections as a co-infection. The Mycoplasma species of M. Pneumoniae and Chlamydia invading the pericardium lining of the heart, seem to be common dominators of myocarditis and pericarditis infections.

Mycoplasma steroid stealing properties also make the energy producing mitochondria leaky by robbing cholesterol lipids that are necessary in mitochondrial membrane integrity. When mitochondria bleed, they cannot generate ATP energy necessary for cell energy and function and nerve cells are the most sensitive to energy deprivation. This explains why chronic fatigue and neurological disorders are the main symptoms of the trinity diseases chronic fatigue syndrome (CFS), fibromyalgia (FMS) and Gulf War illness (GWI). In my opinion, they are the same disease ideology with all three characterizing common symptom traits of chronic fatigue, short term memory loss, low grade fevers, tissue and lymph swelling, joint and muscle pain, stomach and digestive disorders, immuno-suppression and severe systemic chronic infections that invade various organs, tissues and cells including the brain, nervous system and heart.

Mycoplasma Infection Leads To A Medical Merry-Go-Round

Since the disease pattern of CFS, FMS and GWI affect all major body systems (cardio vascular invasion involving the left ventricle, neurological damage ranging from mild cognitive problems to bi-polar depression or schizophrenia, genitourinary damage presenting incontinence or urethritis, pulmonary symptoms of asthma and the development of fibro masses or nodules in the lungs etc.), this multi-faceted symtomatology is causing a medical merry-go-round in the medical profession starting with a general practitioner who will usually prescribe an anti-inflammatory and a short-term antibiotic regimen for the chronic infection.

Since you also exhibit symptoms of neurological disorders and your general practitioner is not versed in neurology, you will be referred to a neurologist.

After the examination with a neurologist and a couple scripts later for your anxiety and insomnia, you will be pawned off on an endocrinologist for your hormonal imbalance because the neurologist has limited knowledge in endocrinology.

Due to the combined adverse side effects of the antibiotics, anti-inflammatories, analgesics and tranquilizers, you may exhibit signs of gastric disturbances and skin reactions where you will be further drugged by a dermatologist or a gastrologist.

Next in line on the "gist" medical treadmill is the cardiologist who will push a beta-blocker or a diuretic on you for your cardiomyopothies. After seeing ten different disease specialists and spending thousands of dollars on MRI's, CT Scans, X-Rays, surgery, pharmaceuticals, etc., without finding a solution to your dilemma, you will be labeled psychosomatic, hypochondriac or suffering from severe depression where you will end up with a psychologist. You're now a walking drug store with more complications than what you started with thanks to the combined adverse reactions of the drugs and the limitations of medical doctors who specialize in only 1/10th of the body. What a racket!!!

Protocols To Treat Mycoplasma

Since Mycoplasma cannot be successfully treated with the usual short course duration of antibiotics due to their intracellular location, slow proliferation rate and inherent resistance to most antibiotics, the few Mycoplasma experts that specialize in this field are recommending six-months to one year of non-stop treatments using strong antibiotics such as Cipro and Doxycycline. However, if a patient does not want to destroy their body and immune system with Cipro and Doxycycline, a total overhaul of every cell from head to toe using a multi-faceted, non-toxic, holistic treatment approach is absolutely necessary to overcome Mycoplasma infections naturally. This is why vitamins and nutritional supplementation are so important in the therapy. Chronic illness patients must also be weaned off antidepressants and other potential immune suppressing drugs before they can fully recover from their illnesses.

The growth cycle of pleomorphics includes a stage as cell-wall-deficient microbes or CWD. These may arise endogenously within our body or arrive from the outside asmycoplasma. Orthodox microbiology does not recognise that CWD can arise endogenously but mycoplasma are known since 1898 as the smallest group of bacteria. The term "myco" indicates fungus-like properties while "plasma" points to the soft shell without a cell wall. They are actually living particles of bacterial nucleic acid and are regarded as being parasites in our body.

Mycoplasma or their spores are so small that, like viruses, they go through bacterial filters and may contaminate blood used for transfusions. Often mycoplasma infections remain symptomless until one suffers a traumatic event or when health deteriorates for some other reason. Because of the missing cell wall mycoplasma do not respond to most antibiotics. Commonly mycoplasma infections are associated with the presence of other pathogenic microbes and parasites.

Of special interest are presently the microbes associated with Lyme disease which can naturally originate from tick bites. The bacteria that cause Lyme disease, the spiral-shaped Borrelia, have been shown to exist in a bacterial as well as in a mycoplasma form and as spores. They also can hide from the immune system by using markers of normal body cells.

Modern Lyme disease started in 1975 as an epidemic in the town of Lyme, Connecticut, close to a biological warfare research laboratory. US government scientists hold a patent on behalf of the US Army for the crystalline mycoplasma fermentans. This semi-synthetic species appears to be much more dangerous than the natural variety (www.publichealthalert.org/Articles/scottforsgren/mycoplasma.htm).

Mycoplasma fermentans is an important agent in several modern diseases which suddenly appeared in epidemic form such as AIDS, Lyme disease, Gulf War Syndrome, and Morgellons disease. Various mycoplasma species are associated with pneumonia, bladder infections, endocrine dysfunctions, gastro-intestinal distress, and other conditions. A key problem with mycoplasma is their disruptive influence on cholesterol and other sterols, and even worse is the toxic effect of the Borrelia spirochete on our lipoproteins, thereby wrecking our fat metabolism.

The microbes of Lyme disease may trigger hundreds of different symptoms and have now been shown to mimic most chronic diseases, especially chronic fatigue conditions, fibromyalgia, and autoimmune diseases in general, but also mental conditions such as schizophrenia, depression, and Alzheimer's disease. Some of these, including Parkinson's disease, could be cured by eliminating the mycoplasma infestation (www.samento.com.ec/sciencelib/4lyme/Townsendhowens.html).

The new Microscope

A new concept in optical microscopy is the grayfield method as developed by Kurt Olbrich (www.grayfieldoptical.com). This allows one to see detailed structures that are otherwise not even visible with conventional phase contrast microscopy. Now it is possible to observe the decomposition of live blood or the pleomorphic changes from spores or viral forms to bacteria and fungi in diseased blood.

Previous researchers of pleomorpic processes were restricted to a magnification of about 2000 times and a resolution of 200 nm while this method allows magnifications of up to 30,000 times and resolutions of less than 100 nm with great depth of focus in natural colours. Therefore everything can now be seen in much greater detail, and even be filmed. Orthodox microbiologists have used conventional analytical methods and theories to prove that the observed Enderlein structures are dead protein aggregates, but if they would instead use the Olbrich method and film the development and movement of these entities then they would be unable to defend their dogma.

I recommend that you watch these two videos: www.grayfieldoptical.com/humoral-pathology.html runs for 22:34 minutes and shows the activity and development of pleomorphics in the blood. A longer video made earlier and of lesser quality but showing additional interesting facts is at www.grayfieldoptical.com/symbiosis-or-parasitism.html (50:50 minutes). Disregard the scientific details of the explanations, and especially the difficult-to-understand names of the various microbes and processes, and just focus on what you see. Even watch it all a second time to let it better sink in.

Also see www.grayfieldoptical.com/files/sanguinogramm.pdf for detailed drawings and descriptions of the development cycle of these pleomorphic microbes. In the head of these club-shaped microbes one can see new spores or viruses evolving, and when the whole structure reaches a certain size the head explodes and releases a new batch of virus-sized particles into the blood. Immune cells or phagocytes gobble up these virus forms, but if there are too many they just continue to develop inside the phagocytes into club-shaped forms. These eventually break out again with large heads full of viruses that they release into the blood.

The Nature of Pleomorphics

These videos show that healthy blood is clean with well-formed red blood cells, also called erythrocytes. In addition there is a faintly perceptible background structure of tiny globules with a single tail. During an acute infection some of these globules grow much bigger and develop a second tail, but after the infection has cleared up they disappear again. If the body is generally more unhealthy or in a so-called pre-cancerous condition then these structures remain permanently visible as round or elongated club-shaped forms.

An interesting phenomenon is the movement of these globules in and out of erythrocytes. Pleomorphics live mainly on our blood sugar, and when it is high they are mainly outside in the plasma but with low blood sugar they move back into the erythrocytes where they find more food. Then after eating sweet food they come back out again.

As the immune system continues to deteriorate fungus-like forms with long threads develop and grow increasingly bigger. The rigid and flexible fibers shown in the pleomorphic videos reminded me of the weird-looking specimens of Morgellons disease that I once viewed. In this disease strange synthetic-looking fibers come out of the skin. This suggests to me that Morgellons may be the result of the crystalline mycoplasma species developed by the US Army.

The time-line shows that the first patent application was in 1986 and the final patent granted in 1993, while the term 'Morgellons disease' was coined in 2002. Successful self-help methods for Morgellons on the Internet seem to be effective against mycoplasma in general. It appears that the US Army started experimenting with mycoplasmasoon after the end of WW2 as suggested by several strange epidemics such as the Royal Free Epidemic of 1955 involving Myalgic Encephalitis, now more commonly called Chronic Fatigue Syndrome or Fibromyalgia.

Large fungal forms are present at the end-stages of cancer and Aids. It is recognised that frequently the cause of death is due to systemic fungus infestations or mycoses. Conventional theory assumes that these are secondary to tumours or the AIDS virus, while the observed pleomorphic life cycle shows that these and their fungal stages are the primary cause why people die of cancer and probably AIDS. The reason for the lethal effects of severe mycoses is probably a combination of poisoning of the energy-producing mitochondria inside cells by fungal toxins and the destruction of erythrocytes by pleomorphics.

These pleomorphics not only fill the inside of red blood cells and deplete them of nutrients, they also form spines and long protrusions in the cell wall when they move out into the plasma. Someone with myasthenia gravis, an autoimmune disease, once mentioned that he was shocked to see that most of his red blood cells looked like black sea-urchins. These erythrocytes can no longer supply nutrients to the body and are quickly destroyed in the spleen.

This is the real cause of severe anaemia that is so common in advanced cancer and various other diseases. In the end stages of cancer nearly 100% of erythrocytes are strongly infested and dysfunctional. This then leads to cachexia (muscle wasting with extreme fatigue) as the leading cause of death in cancer and AIDS. However, as shown in the longer video, with special Enderlein vaccines even in advanced cancer the erythrocytes could be returned to health within one month with simultaneous shrinking of existing metastases.

You may wonder how it is possible for a single cause such as an overgrowth of the blood with pleomorphics to lead to many different diseases. The answer is basically the same as why a cyclone or hurricane can destroy one building and leave another one undamaged, or rips off the roof of one and causes water damage in another. When the immune system is severely weakened then any pathogens have free range, and the weakest organ will be the first to crumble.

c) Other Infectious Diseases as the Underlying Cause of CFS

What infectious diseases can prompt CFS and why?

Clinical reality has proved over the years that chronic fatigue syndrome (CFS) is a complex disorder, which does not have one absolute cause behind it. Rather, there are multiple underlying causes that feed off of each other and together manifest as chronic fatigue. Further, the group of factors that may cause one person’s illness may be different from someone else with similar symptoms.

Infections can either trigger or contribute to CFS. These may include viruses such as Epstein Barr or herpes, or bacterial infections, including Lyme disease. Chronic fatigue syndrome is not a “mysterious” disease anymore. It can be treated, if all underlying factors are properly diagnosed and addressed.

Infections Present With Chronic Fatigue Syndrome

Numerous studies have demonstrated a high incidence of chronic infections in chronic fatigue syndrome. These include viral infections of Epstein Barr (EBV), cytomegalovirus (CMV), human herpes virus-6, (HHV-6), and bacterial infections such as mycoplasma, chlamydia pneumonia (CP) and Borrelia burgdorferi (Lyme disease).

A study published in Acta Pathologica, Microbiologica et Immunologica Scandinavica found that 52% of CFS patients had active mycoplamsa infection, 30.5% had active HHV-6 infection, and 7.5% had Chlamydia pneumonia infections vs. only 6%, 9% and 1% of controls, respectively.

Another study published in the Journal Immunology and Medical Microbiology also confirmed there is a high incidence of active mycoplasma infection among European CFS patients. It was revealed that 68% of these patients had an active mycoplasma infection as diagnosed with specialized polymerase chain reaction (PCR) testing.

Why Are These Infections Present in Chronic Fatigue Syndrome Patients?

Due to the immune dysfunction seen in CFS patients, there may also be a lack of IgG antibodies present. It has also been shown that the presence of antithyroid antibodies in CFS patients has a significant correlation with active HHV-6 infection. There is also evidence that CFS may be due to the above discussed infections with “stealth adaptation”. This notion refers to certain viruses, which can avoid immune elimination by deleting genes required for effective antigenic recognition by the cellular immune system. Such viruses don’t have to confront the body’s cellular immune defense mechanisms and can, therefore, evade the immune system and create persistent ongoing infections.

Why Are These Infections Often Undetected?

There is controversy regarding the presence of active infections in CFS patients because physicians, including infectious disease specialists, do not understand that the standard way to diagnose acute infections, an elevation of IgG and IgM antibodies, is not a sensitive means of detecting chronic infections in such cases.

Chronic reactivating infection, such as those mentioned above, do not stimulate IgM antibodies as they are not new infections, but rather intracellular reactivating infections. Most doctors will tell patients who have elevated IgG antibodies that they had an old infection or previous exposure and that there is no evidence of, or they do not have an active infection, because that is what they learned in medical school.

But this standard way of detecting active infections has clearly been shown to be inaccurate and miss the overwhelming majority of patients with active infections.

Polymerase chain reaction (PCR) testing is much more sensitive in a research setting than in the clinical setting because if the blood sits for more than a few hours, the infectious organism’s DNA degrades and often goes undetected. The lack of sensitivity is also determined by the fact that these infections are not concentrated in the blood, but rather in the tissues, especially nerves, brain and the white blood cells.

Physicians must have a high incidence of suspicion and look for elevated IgG or early antigen (EA) antibodies along with other signs of chronic infections including low natural killer cell activity, high RNAse-L activity, high ACE (> 35), coagulation activation, high tumor necrosis factor (TNF), low melanocyte stimulation hormone (MSH), high interleukin-6 (IL-6), low WBC, increased 1-25 vitamin D/1-25 vitamin D ratio and elevated or decreased total IgA, IgM or IgG levels.

At Holtorf Medical Group we use a multi-system treatment approach for CFS, which produces significant results in a high percentage of patients and was further confirmed through the analysis of the cumulative findings of over 40 independent physicians and over 5,000 patients.

– Holtorf Medical Group, Resources: Infectious Causes of Chronic Fatigue Syndrome

When one is ill with a virus, it is not the virus which makes one feel ill, it is the body's response to that virus. The immune system fights infections by releasing immune mediators like interferons, cytokines (cell killers) etc. These substances, our own toxins, are thought to be the substances which make CFS sufferers feel ill. It is thought that part of the problem with post viral fatigue is an on-going reaction to virus, even after the virus has gone. i.e. the immune system has become switched on and can't turn off. In this respect the immune system is responding in an allergic way - ie on-going unnecessary activity which is simply making the sufferer ill.

This means that treatment should be aimed at the immune system to persuade it to respond appropriately - ie not in a pro-inflammatory way. See Inflammation.

Other suspects. Use the following as a check list to make sure these possibilities have at least been considered:

Some chronic infections need specialist treatment in their own right, such as hepatitis B and C and HIV infection.

Gut dysbiosis. See Fermentation in the gut and CFS.

Helicobacter pylori: a blood test for helicobacter pylori antibodies is now available at most district general hospitals so your GP should be able to do this. H pylori infection can also be tested for by a helicobacter pylori breath test. Indeed, if you have had eradication therapy for H pylori, then this is the follow-up test to see if eradication has worked (antibody levels remain positive for many months after).

Urinary tract infections can be tested for using the multistix urine testing kit (this can be ordered through my online sales website at Sales at Dr Myhill for packs of 25 Multistix). This looks for a range of abnormalities. If there is infection, expect to see positives for protein, nitrites and/or leucocytes. Positive results need treatment with antibiotics. I usually start with a "best guess" antibiotic such as trimethoprim. But a full sample of urine (mid stream urine microscopy and culture) should also be sent off to ascertain which bacteria are there and to which antibiotic it is sensitive. See Irritable Bladder Syndrome.

Pelvic inflammatory disease and prostatitis. If you want to be tested, please contact my office and I shall refer you to The Doctors' Laboratory for an appropriate test. The usual ordering process as in Ordering Tests will apply.

The available blood tests are as follows, with the possible reasons for getting them done:

Amoebic antibodies. If illness started with gastroenteritis when living in an area of poor sanitation. Treatable with drugs.

Borrelia antibodies (Lyme's disease). Contact with ticks from sheep or deer. I honestly do not know the best way to diagnose and treat this problem! The tests are not reliable neither to my mind is the treatment!

Brucella antibodies: Usually acquired in parts of Europe, Middle East, Central and South America.

Chlamydia antibodies . Chlamydia is a group of bugs also called mycoplasma, the smallest known free living organisms. They cause a variety of diseases including pneumonia, but the commonest problem associated with fatigue is sexually transmitted disease - pelvic inflammatory disease in women and prostatitis in men. Men may have no symptoms of infection. Sexually transmitted diseases are the commonest chronic infections in UK. Chlamydia may also be responsible for: Gulf War syndrome mycoplasma incognito - difficult to test for and treat.

Psittacosis (from parrots) and ornithosis (from birds) - rare

Echinococcus (tapeworm) antibody. Tapeworms are usually acquired from dogs.

Enteroviral antibody screen (coxsackie virus, adenovirus, polio virus and echo virus). These common viral infections may cause no illness at all, gastroenteritis or 'flu-like symptoms. There is no specific treatment for these infections.