Tez özetleri Astronomi ve Uzay Bilimleri Anabilim Dalı

The Effects of Temperature and Humidity on the Anesthetic gases

Within the framework of quality management endeavors in medical services, calibration gained great importance through appropriacy of medical devices. The aim (goal, objective)of this study is to investigate the effects of temperature and humidity factors to the amount of gas output from the vaporizer and to enhance the consideration of these factors while adjusting he amount of gas to be given to the patient during(through) the operation(surgery).

The definition and types of anesthesia are studied in the first section of the thesis. Historical development of anesthesia is studied with classification of anesthetic agents according to their field of use. Advantages and disadvantages of Low Flow Anesthesia, which became a routine technique in clinical applications, are discussed. The risks of Low Flow Anesthesia and technical precautions in order to reduce the rate of these risks are considered.

Volatile agents ready to evaporate, especially formulated volatile agents, are organic liquids and they are applied to the patient through the respiratory system during induction and maintenance of general anesthesia. Isoflurane and sevoflurane are the most commonly used agents in Low Flow Anesthesia applications. The properties of isoflurane and sevoflurane gases are studied with their technical comparisons. In the final part of the first section of this study the effects of temperature and pressure to the anesthetic gas concentration and the rate of change in anesthetic depth under different values of temperature and pressure are introduced.

In the second and third sections of the thesis, the application areas and application techniques of machines (devices) used in anesthesia are introduced. In this study, the performance of the anesthesia machine is evaluated with whether it supplied the dialed amount of anesthetic to the patient. Then, through changing the temperature and humidity values (rates) of anesthetic device, the results of changes in these factors are observed. The changes in the effects of isoflurane and sevoflurane gases according to the temperature-humidity factors are measured. The data gathered (elicited) are evaluated with biostatistical study and also mathematical modeling including temperature-humidity factors is formed.