#The most dangerous complication of ACE inhibitor therapy:
-cough
-gipokaliemiya
+angioedema
-hypotension
-violation
renal function
# A week later, receiving clonidine with good effect, blood pressure rose again. The mechanism of resistance
+ sodium and water retention
- addictive
- paradoxical reaction
- accelerating metabolism
- the acceleration of excretion
# Mechanism ulcerogenic NSAIDS:
- overproduction of gastrin
+inhibition of prostaglandin synthesis
- stimulation of the formation of thromboxane
- increased production 3.5 - c-AMP
- increased synthesis of prostaglandins
# When changing from parenteral administration GCS hormones on their oral dose should be:
-increasein 2-5 times
+reduced by 2-5 fold
-reduce 1.5-2 times
-increase1.5-2 times
-still unchanged
# ACE inhibitors are contraindicated in:
+double-sided renal artery stenosis
-vasorenal hypertension
-hypertonic lung disease course
-hypertonic disease moderate flow
-hypertonic disease and coronary heart disease
# Which antihypertensive drug is contraindicated for pregnant women?
-gidralazin
-metoprolol
-nifedipin
+captopril
-prazozin
# Specify the drug of choice in the treatment of hypertension in patients with concomitant coronary artery disease:
-apressin
-reserpine
+metoprolol
-klofelin
-nifedipin
# Specify the drug of choice for hypertension combined with obstructive syndrome:
+verapamil
-anaprilin
-reserpine
-sotalol
-raunatin
# Specify the drugs of choice in the treatment of hypertension and diabetes mellitus:
-tiazidovye diuretics
-beta blockers
calcium antagonists
+ACE-inhibitors
alpha-blockers
# What is a side effect commonly observed in the appointment of verapamil?
-swellinglegs and feet
+bradycardia
-hypotension
-prilivy
-reflector tachycardia
# Contraindication for beta-blockers:
- hypertension
+hypothyroidism
- stable angina
- beats
-tachycardia
# What types of adrenergic receptors stimulates norepinephrine (noradrenaline) ?:
+ alpha, beta1
- alpha, beta 2
- beta2
- alpha1, beta1, beta2
- alpha2, beta1, beta2
# Adrenoceptors stimulated by epinephrine (adrenaline) ?:
-only alpha
-only alpha, beta 2
- only beta
- only alpha1, beta1
+ alfa1,2, beta1,2
# Which drug is an ACE inhibitor ?:
-atenolol
-verapamil
+enalapril
-rilminidin
-indapamid
# Which drug is a beta-blocker ?:
+bisoprolol
-ramipril
-benzogeksony
-reserpine
-gidralazin
# Specify the drug, an angiotensin-2 receptor blocker? :
- perindopril
+ valsartan
- indapamide
- moxonidine
-nifedipin
# Preparations of calcium antagonists is:
-raunatin
-klofelin
+amlodipine
-kaptopril
-lozartan
# What is the route of administration of drugs for hypertensive crisis most rational:
+ sublingual
- inside
- rectal
- intramuscular
- intravenous
# Alpha-blockers include:
-amlodipine
-klofelin
+doxazosin
-kaptopril
-lozartan
# Thiazide diuretic used in the treatment of essential hypertension:
-gipotiazid
+indapamide
-furosemid
-diakarb
-spironolakton
# What types of dopamine receptors stimulate?
-only alpha
-only dopamine
- only Beta
- only alpha1, beta1
+ alpha, beta, dopamine
# Most of the daily dose of prednisolone should be administered:
+morning
-day
-in the evening
-for the night
-at night
# Side effects of glucocorticoids:
-hypotension
-bronhospazm
-drowsiness
+diabetes
-hyperkaliemia
# Prednisolone pulse therapy is used to treat:
- pneumonia
- rheumatism
- rheumatoid arthritis
+ systemic lupus erythematosus
-dermatomiozita
# In the treatment of anaphylactic shock are used:
+ epinephrine, prednisone
- atropine, vikasol
- dibazolum, pentamin
- corvalol, nitroglycerin
-nifedipin, clonidine
# The most pronounced anti-inflammatory action has:
-metamizol (analgin)
-piroksikam
+indomethacin
-ibuprofen
-paracetamol
# Aspirin in comparison with indomethacin has a more pronounced:
-analgetic
+ antiplatelet
-hypothermic
-antiinflammatory
-desensibilisation
effect
# Side effects of NSAIDs are due to:
-blockage phospholipase A-2
+ blockade of cyclooxygenase-1
-blockade cyclooxygenase-2
-a direct toxic effect on tissues
-blockade lypoxygenase
# What are the clinical effects of NSAIDs appear before other?
+ antipyretic
- anti-inflammatory
-desensitizing
- antiplatelet
- immunosuppression
# Contraindications to the basic anti-inflammatory drugs is:
- rheumatoid arthritis
- vasculitis
- psoriasis
+pregnancy
- carditis
# For what purpose are used allopurinol ?:
- how antipyretic
- as an analgesic
+ to treat gout
- for the prevention of influenza
- for the treatment of rheumatoid arthritis
# Specify the drug inhibits the biosynthesis of uric acid:
-colchicine
-benzbromaron
-indometatsin
+allopurinol
-aspirin
# The use of corticosteroids is dangerous to the fetus ?:
- prednisolone
+ fluorinated corticosteroids
- hydrocortisone
-
SCS with metil
- dexamethasone
# Specify the nonselective beta-blockers:
- metoprolol
+ propranolol
- atenolol
-nebivolol
-bisoprolol
# What is the antihypertensive agent is contraindicated in patients suffering from hypertension and asthma ?:
-nifedipin
+bisoprolol
-indapamid
-verapamil
-valsartan
# Specify the typical side effects of nifedipine:
-the development of AV-blockade
-bradycardy
-bronchospasm
+reflex tachycardia
- dry cough
# Specify the immunostimulatory drugs:
-prednisolon
+ interferon
-dimedrol
-ibuprofen
-delagil
# Specify a drug used for the relief of hypertensive crisis:
+ nifedipine
-enalopril
-bisoprolol
-indapamid
-amlodipine
# Specify the irrational drug combinations in the treatment of hypertension:
+ beta-blockers + verapamil, diltiazem
-diuretik + beta-blocker
-calcium antagonist + ACE-inhibitors
-diuretik + ACE-inhibitors
-digidropiridinovy calcium antagonist + beta-blocker
# Which drug has a minimum ulcerogenic activity?
+ ibuprofen
-indometatsin
-aspirin
-butadion
-diklofenac
# Which diuretic effective in the glomerular filtration rate of less than 10 ml / min:
-diakarb
-indapamid
+torasemide
-amilorid
-gipotiazid
# Which drug reduces effects of furosemide:
-atropine
-ventolin
-reserpine
-verapamil
+voltaren
# If a clinical situation diuretics are not effective:
-hypercalciemy
+hyponatremia
-giperalbuminemiya
-arterial hypertension
-liver insuffiency
# Which drug potentiates the delay in the appointment of potassium when prescribing amiloride:
-nebivolol
+ captopril
-furosemid.
-nitrosorbid
-gipotiazid
# Specify the dosing regimen of furosemide:
-10-50 Mg / s
-600 Mg / sec
+ 40-600 mg / s
-not menee500 mg / s
-only 100 mg / s
# Choose the correct statement:
-furosemide causes hyperkalemia
-diakarb - a powerful diuretic
+torasemide-strong diuretic
- mannitol causes acidosis
- pananginum indicated in hyperkalemia
# Specify the dosing regimen indapamide:
-40 Mg / day
-100 Mg / day
+1.5-5 mg \ day
-25-50 Mg \ day
0.5 mg \ day
# For security diuretic therapy control everything, except:
refractive acid-base balance
-kreatinin
-electrolit
+fundus
-central hemodynamics
# Which drug is short-acting diuretic:
-indapamid
+ mannitol
-diakarb
-gipotiazid
-veroshpiron
# What diuretic, causing the loss of potassium 1: 1:
-furosemid
-diakarb
-mannitol
+hydrochlorothiazide
-amilorid
# Why NSAIDs cause resistance to loop diuretics.
-sweling bowel wall
-at the expense of hyperuricemia
-acceleration elimination
+blockade of prostaglandin
-konkurentsiya for communication with protein
# Loop diuretics in all states is a means of selecting, except:
-swelling syndrome in circulatory failure
+ hyponatremia
-hypercalciemy different genesis
-hyperkaliemy
-nephrotic syndrome
# Diacarb effective in all states, except:
-metabolic alkalosis
-glaucoma
-epilepsy
- craniocerebral hypertension
+pulmonary heart
# Side effects furosemid include everything except:
-hypokaliemia
+decrease in glomerular filtration rate
-hyperurecimia
-ototoxicity
-hypovolemia
#Assignment thiazides shown at:
-heavy liver failure
-terminal renal failure
+diabetes insipidus
-podagra, acute phase
-circulation insufficiency 3 degrees
# Diuretic effect "thiazide and notiasid" drugs will stop when the largest glomerular filtration rate of less than ml / min:
+30
-80
-60
-70
-65
#Patients with coronary heart disease and postinfarction cardiosclerosis developed pulmonary edema. Diuretic choice:
-mannitol in / veno
+ furosemide / intravenous
-gipotiazid inside
-veroshpiron inside
-diakarb inside
# To correct resistance to diuretics in the nephrotic syndrome should be appointed:
+albumin infusion
-furasemid infusion
-infusion saline
-polarised mixture
-reosorbilakt intravenously
# Resistance to diuretics in congestive heart failure caused by:
-blockaga prostaglandins
-decrease in existing nephrons
-urine protein-bond
+ incomplete and delayed absorption
-quick elimination
# For all antacids are typical side effects, except:
-vismut oxide encephalopathy
- magniy oxide- diarrhea
+ accomodation
-aluminium hydrooxide- constipation
-carbonate, calcium alginate - nephrolithiasis
# Specify the method for preventing the development of tolerance to nitrates:
-replacement nitrate warfarin
-decreasing dose
-increasethe number of intakes
+ designation "correctors" (ACE)
-admitting Riboxin
# Specify the preferred group of anti-anginal drug in vasospastic angina variant:
-beta blockers
+ calcium antagonists
-direct
anticoagulants
-inhibitory ACE
-diuretics
# Specify the use of lipid-lowering drugs for primary and secondary prevention of coronary heart disease:
-tsiprofibrat
-enduratsin
-omego-3 PUFAs
+ atorvastatin
-holesteramin
# Name the drug, approved for use during pregnancy:
+maalox
-famotidin
-omeprazole
-de-nol
-pantoprazol
# Specify the main pharmacodynamic effects M-anticholinergics, except:
+ weakening of peristalsis
-extension of the pupil
-paralich accommodation
-increaseintraocular pressure
-tachycardia
# Highlight nitrate prolonged duration of action:
-nitroglycerin tablets
+isosorbide-5-mononitrate
-aerosol nitroglycerin
-izosorbid dinitrate
-plastyr nitroglycerin
#Specify the interaction loop diuretics with other drugs:
-reduces digoxin toxicity
+increasethe ototoxicity of aminoglycosides
-weakening hypotensive effect
-reduces nephrotoxicity of cephalosporins
-reduces effects of anticoagulants
# Name the condition requiring the appointment of fibrates:
-drug choice for hypercholesterolemia
- diabetesinsipidus
-low level of triglycerides
+hypertriglyceridemia
-hypertriglitseridemia homozygous
# Name Pharmacokinetics of isosorbide mononitrate:
-low bioavailability
-availability presystem elimination
-effect first passage
+high bioavailability
-time action 10-30 minutes
# Specify the mechanism of action of statins:
-decreasing cholesterol synthesis
+HMG-CoA reductase
-changing with chloride ions
-improves the activity of lipoprotein lipase
-reduces prostaglandin synthesis
# -Specify One of the most important areas of the treatment of coronary artery disease:
-hypoglicemic therapy
-antisecretor treatment
-antiinflammatory treatment
-eradicative treatment
+antianginal therapy
# What are the enzyme preparation:
-omeprazole
+pankreatin
-maaloks
-almagel
-metoklopramid
# What are the primary pharmacodynamic effect of spironolactone:
+ competitively inhibits aldosterone
-increasing renal blood flow
-effecs speed filtering
-increasing osmotic pressure
-increaseof uric acid
# Specify the indications acetazolamide:
-arterial hypertension
-diabetes
-nephrotic syndrome
-cirrhosis liver, ascites
+ intracranial hypertension
# Specify the side effect of diuretics:
-extrasistoly, bradycardia
-bronchospasm, diathesis
+ hypokalemia, hyponatriemia
-arterial hypertension
-metabolic acidosis
# Specify the antiemetic drug:
-omeprazole
-tsimetidin
+ondansetron
-papaverine
-atropine
# Specify the indication for histamine H2-blockers:
-chronic active hepatitis
+peptic ulcer
-nonspecific ulcerative colitis
-acute hepatitis
-athresia bile ducts
# Specify the drug used in the failure of exocrine function of the stomach:
+ hydrochloric acid
-ascorbic acid
-famotidin
-almagel
-dyuspatalin
# Which of these cardiac glycosides refers to polar:
-digitoksin
-atsetildigitoksin
+strophanthin
-digoxin
-celanid
# Which of these cardiac glycosides almost significantly associated with plasma proteins:
-celanid
-corglikon
+digitoksin
-strofantin
-atsetilstrofantin
# cardiac glycosides is contraindicated in:
+ ventral paroxysmal tachycardia
-paroxism atrial fibrillation
-tachysystolic atrial fibrillation
-congestive heart failure
-prophilaction AV reciprocating tachycardia
# Contraindications to the appointment of cardiac glycosides everything except:
-syndrome sinus
-syndrome WPW
-appearing sinus bradycardia
-AV Blockade degree I-II
+atrial fibrillation
# Which of these side effects not characteristic of digitalis intoxication:
-increasing heart rate
-ventral arrythmia
+reduction in blood pressure
-dyspeptic disorders
-AV blockade
# When concomitant administration of anticoagulants and antibiotics broad-spectrum effect of anticoagulants:
-decreases
-not changes
+ increases
-not studied
-neutralise
# Based on the index of coagulation is compensated dose anticoagulants?
-content of antithrombin III
-time blood clotting
-etanolovy test
+
prothrombin index, international normalized ratio
-the concentration of fibrinogen
# What are anticoagulants used in atrial fibrillation?
-streptocinaza
-heparin
+ warfarin
-fraksiparin
-hirudin
# With some blood factors related pharmacodynamic activity of heparin:
-Hageman factor
-proatserilin
+antithrombin III
-factor II
-factor VII
# Which drug can cause "rebound" of thrombosis?
+ heparin
-tiklid
-gordoks
-reopoliglyukin
-dipiridamol
# What are the methods of control of antiplatelet therapy?
+ platelet counts
-time coagulation
-the concentration of fibrinogen
-product fibrinogen degradation
-protrombinovoe time
# Labaratory method of monitoring heparin therapy?
- prothrombin time
-trombotest
-ethanol test
+time of blood coagulation
-concentration of fibrinogen
# Specify the method of emergency treatment of an overdose of heparin?
-konakion
-fresh frozen plasma
+protamine sulfate
-vikasol
-ditsinon
# What is the drug used in overdose coumarin derivatives:
-fibrinogen
-ditsinon
-protamina sulfate
-new freezed plasma
+ vikasol
# In case of overdose antiagregants your tactics:
+etamsylate sodium 250-1000 mg / in
-konakion 10-20 mg
-protamina sulfate 50-100 mg / in
-aminocapron acid
-vikasol
# Which of the following is used for thrombolytic overdose:
+ aminocaproic acid
- protamina sulfate
-ditsinon
-konakion
-fresh frozen plasma
# How should change the clotting time in the appointment of heparin?
-elongating 4 times of the original
-does not change
+ extension 2-2.5 times
-changes are dose dependent
-truncation 2-3 times
# What are the main method of monitoring the effectiveness and safety of thrombolytic therapy:
-clotting time
+ concentration of fibrinogen
-protrombinindex
-protrombin time
-etanol test
# If a clinical situation cardiac glycosides are used:
- ventricular fibrillation
- AV block II Art
-infarction
-arterial hypertension
+ atrial fibrillation
# Choose a rational combination of drugs used in the treatment of CHF pathogenesis:
- furosemide + amidaron+ nitrosobid
- nitrosorbid + reserpine +aspirin
+enalopril + bisoprlol +veroshpiron
-digoksin+ metopralol + indapamide
-klofellin + ramipril + nebivalol
# Vitamin C in high doses may cause:
-hypotension
+formation of kidney stones
-tachycardia
-obostrenie peptic ulcer
-bronhospasm
# Name therapeutic doses of ascorbic acid:
- 15-50 mg / day
-1,5-2 Mg / day
+ 200-500 mg / day
-10-20 Mg / day
-50-150 Mg / day
# Specify the indications of spironolactone:
-hyperkalemia
-swelling leg and foot
+CHF II-IV NYHA functional class
-ginekomastiya
-increasethe level of creatinine
# Name indication for alteplase:
-unstable angina
-treatment venous thrombosis
-stable angina
+ acute myocardial infarction
-prophylactic venous thrombosis
# For low molecular weight heparin include:
- hirudin
-alteplaza
+ enoxaparin
-tiklopidin
-varfarin
# Thrombolytic therapy in myocardial infarction is aimed at:
-pain relief
-normalization AD
-increaseblood pressure
+ limit the area of necrosis
-profilaktika arrhythmias
# Disaggregation mechanism of action of aspirin is associated with:
+ inhibition of production of thromboxane A2
-increasethe synthesis of prostacyclin
-blokada vWF
-violation synthesis of ADP
-blokada phosphodiesterase
# Side effects of heparin include everything except:
- allergic reactions
-alopecia
-arterialnaya hypotension
-bleeding
+ pulmonary fibrosis
# What kind of a structure of a microorganism cephalosporins have an effect:
+ cell wall
-ribosome
-core
-mitochondry
-vakuol
# What side effects characteristic of aminoglycosides:
+ nephrotoxicity
-kardiotoxicity
-gastropathy
-blurred vision
- movement disorder
# Which group of antibiotics often causes allergic reactions:
+ penicillins
-aminoglikozids
-makrolids
- sulfonamides
-linkozamins
# Name antibiotic for exposure to sensitive strains of Streptococcus Pneumoniae in the treatment of pneumonia:
-ciprofloxacin
- gentamicin
+cefotaxime
-doksitsiklin
-tetratsiklin
# Which antibiotics creates high concentrations in the prostate gland:
+ciprofloxacin
-linkomitsin
-ampitsillin
-erythromycin
-vankomitsin
# Which antibiotics should be prescribed for exposure to micro-organisms that produce beta - lactamase:
-penicillin
-ampitsillin
-tsefazolin
+ amoksicillin+clavulanic acid
-amoksicillin
# Select the antibacterial agent for the treatment of pneumonia caused by Mycoplasma pneumoniae:
-linkozamids
-penitsillins
-tsefalosporins
+ macrolides
-aminoglikozids
# Which is bactericidal antibiotics:
-tetratsiklin
-linkomitsin
-chloramphenicol
+ amikacin
- erythromycin
# The dosage regimen of antibiotic should be changed with symptoms of renal failure:
-tseftriakson
+ gentamicin
-doksicyclin
- erythromycin
-tsefoperazon
# Which produces high concentrations of antibiotic in the bone:
-gentamicyn
-nalidiks acid
+linkomysin
- erythromycin
-cefatoksim
# What is the side effect is not specific to ampicillin:
-rash
-allergic reaction
-diarrhea
- vaginal candidiasis
+nefrotoxity
# Choose the safest antibiotic for the treatment of pregnant women:
+ampitsillin
-gentamitsin
-ciprofloksacyn
- chloramphenicol
-biseptol
# Select the drug for the treatment of sepsis caused by MRSA:
-ampitsillin
-tsefazolin
-thien
-azitromitsin
+ linezolid
# Selekt the most effective anti-pseudomonal drug:
-amoksitsillin
-sefotaksim
-sefozolin
+ meropenem
-gentamitsin
# Note the anti-pseudomonal cephalosporin:
-tsefazolin
-tsefotaksim
-tseftripakson
+cefepime
-tsefaklor
# What preparation is referred to as "respiratory" fluoroquinolones:
-siprofloksatsin
-ofloksatsin
-norfloksatsin
+ levofloxacin
-lomefloksatsin
# What is an antimicrobial drug is contraindicated in children:
-penicillin
-tseftriakson
-azitromitsin
+ciprofloxacin
-eritromitsin
# Select antiherpetic drug:
-remantadin
-zanamivir
+ acyclovir
-oseltamivir
-arbidol
# Select a fluoroquinolone anti-anaerobic activity:
+ moxifloxacin
-levofloksatsin
-tsiprofloksatsin
-sparfloksatsin
-norfloksatsin
# Select the drug for the treatment of pseudomembranous colitis:
-penicillin
-tsefotaksim
-thien
+ vancomycin
-klaritromitsin
# Select an antifungal medication for the treatment of vaginal candidiasis:
-vorikonazol
-teratsiklin
+ fluconazole
-terbinafin
-amfoteritsin
# Mark derivative of 8-hydroxyquinoline:
+ nitrksolin
-etazol
-acids nalidixic
-tsiprloksatsin
-metronidazol
# Nucleoside derivatives for the treatment of HIV infection:
-atsiklovir
+ zidovudine
-guanidine
-gantsiklovir
-zanimivir
# Specify a drug belonging to the macrolide antibiotics:
-neomitsin
-doksitsiklin
+ clarithromycin
-tsefaloridin
-linkomitsin
# Which refers to a group of antibiotics monobactams:
-ampitsillin
-bitsillin 5
+ aztreonam
-imipenem
-levofloksatsin
# Which is not an aminoglycoside drugs:
-gentamitsin
-streptomycin
+ clindamycin
-neomitsin
-amikatsin
# Which is not a fluoroquinolone drugs:
-ofloksatsin
-ciprfloksatsin
+ ceftazidime
-levofloksatsin
-norfloksatsin
# Which is not penicillin drugs:
-ampitsillin
-amoksatsillin
-tikartsillin
+ vancomycin
-piperatsillin
# Do not recommended for the treatment of pyelonephritis:
-tsiprofloksatsin
-tsefotaksim
+ chloramphenicol
-amikatsin
-amoksitsillin / clavulanate
# Which group of antibiotics is ticarcillin:
+ penicillins
-makrolidy
-tsefalosporiny
-ftorhinolony
-monobaktamy
# Which group of antibiotics cefepime is:
-penitsilliny
-makrolidy
+ cephalosporins
-ftorhinolony
-monobaktamy
# Which group is antibiotics piperacillin:
+ penicillins
-makrolidy
-tsefalosporiny
-ftorhinolony
-monobaktamy
# Which group of antibiotics include ciprofloxacin:
-penitsilliny
-makrolidy
-tsefalosporiny
+ fluoroquinolones
-monobaktamy
# Etiotropic therapy for pneumococcal pneumonia:
+ cefazolin
-eritromitsin
-chloramphenicol
-linkomitsin
-azithromycin
# The use of ipratropium bromide as a bronchodilator in asthma everything except:
- "physical force"
+ viscous mucus
-
nocturnal attacks
-with abundant mucus secretion
-with concomitant glaucoma
# Sick "avid" smoker gets theophylline. How does smoking on the half-life of theophylline:
-udlinitsya
+ shortened
-essential not change
-significantly be extended
-anonymous
# The most dangerous side effect of sympathomimetic overdose in patients with asthma is:
-tremor jitter
- mental excitement
-tachycardia
+ symptom of "locking"
-nausea, vomiting
# With the simultaneous use of theophylline and beta-2-agonists include the following changes in effect:
+ potentiation
-leveling
-antagonism
-weakening action
-side effects
# Of selective beta2-agonist is:
-izoprenalin
-ortsiprenalin
-adrenalin
-bekotid
+ terbutaline
# Side effects of beta 2-agonists does not concern:
-tahifilaksiya - resistant chronic administration
-syndrome "ricochet"
-syndrome "blocking light"
+ bradycardia
-tremor, dyspepsia
# H1-histamine blockers are most effective when:
-profilaktike nonallergic inflammation
-Treatment allergic reactions
+ prevention of allergic reactions
- The treatment of non-allergic inflammation
- Exacerbation of peptic ulcer disease
# Lack of antihistamines I generation all except:
-tahifilaksiya
- CNS depression
-tachycardia
-atoniya intestine
+ Cough
# For I generation antihistamines do not include:
- Diphenhydramine
- Suprastin
-fenkarol
+ cetirizine
-tavegil
# A typical side effect of antihistamines II generation:
- CNS depression
+ cardiotoxicity
-atoniya intestine
-atoniya bladder
- tachyphylaxis
# Specify the type 4 phosphodiesterase inhibitor, which is used in severe COPD:
-eufilong
-teopek
+roflumilast
-teodart
-retafil
# The clinical effect of inhaled corticosteroids develops after:
-1-2 Hours
-20-24 Hours
+ 2-4 days
-1 week
-2-3 weeks
# Fexofenadine Duration:
-2 hours
-6 hours
-12 hours
-24 hours
-48 Hours
# Indications antihistamine drugs:
-stomach ulcer
-glomerulonefrit
+ hay fever
-cirrhosis of the liver
-tuberculosis
# Preparations for pathogenetic therapy of chronic specific inflammation in COPD:
+ roflumilast, salmeterol, beclomethasone
-klaritin, fenoterol, nizartidin
-montelukast, libeksin, Inderal
-salbutamol, fluticasone, lazartan
-ambroksol, Atrovent, fluconazole
# By selective beta2-agonists does not concern:
+ isoproterenol
-salbutamol
-salmeterole
-terbutalin
-formoterol
# Intalum when combined with beta 2-agonists effect of the latter:
-reduces
-not changes
-significantly reduced
+ enhanced
-side effects
# The main indication for nasal cromoglycates the:
-bronchial asthma
+ allergic rhinitis
-recidiv urticaria
-food allergies
-purulent sinusitis
# What are the optimal route of administration of bronchodilators for chronic obstructive pulmonary disease:
-intramuscular
-under skin
+ inhalation
-peroral
-intravenous
# To reduce the pulmonary hypertension in patients with chronic obstructive pulmonary disease, can apply everything except:
+ propranolol
-kaptopril
-nitrong
-eufillin
-nifedipin
# In some cases, antibiotic treatment is shown an exacerbation of chronic bronchitis:
-in all cases
-with obstructive syndrome
+ purulent sputum
-bolnye over 55 years
-the presence of pulmonary emphysema
# Maintenance dose aminophylline on exit from the patient's asthmatic status:
+3 mg / kg every 6 hours
-6 Mg / kg every 8 hours
-3 Mg / kg every 12 hours
-6 Mg / kg every 12 hours
-3 Mg / kg once a day
# The main goal in the treatment of COPD:
+ reduction in the progression of the process
-complete cure the patient
-oblegchenie symptoms
-is the inverse development of emphysema
-preparation for surgical treatment.
# The concentration of theophylline in serum, causing bronchodilation:
-5 To 10 ug / ml
+10 -20 mkg / ml
-15-25 Mg / mL
-up 20 ug / ml
-20-30 Mg / mL
# The patient was admitted in asthmatic status. What is the "loading dose of aminophylline":
+5.6 mg / kg
- 3 mg / kg
- 8 mg / kg
- 2.8 mg / kg
- 10 mg / kg
# The concentration of theophylline in serum, causing toxicities
-5 To 10 ug / ml
-10 -20 mkg / ml
-15-25 Mg / mL
+ above 20 mkg / ml
-20-30 Mg / mL
# When you cough with purulent sputum is contraindicated in:
-bromgeksin
+ codeine
-mukaltin
-ambroxol
-atsetiltsistein
# Emergency aid for attack of asthma:
+ salbutamol
-codeine
-libeksin
-teofil
-montelukast
# For acute asthma is not appointed:
+ sodium cromoglycate (Intal) - inhalation
-prednizalon intravenously
-fenoterol - inhalation
-eufillin intravenously
-salbutamol - inhalation
# For Inhaled steroids include:
-gidrokortizon
-triamtsinalon
-prednizalon
-deksametazon
+ beclomethasone
# The effect of drugs on the body of the sick person is studying
-pharmacy
-eksperimental pharmacotherapy
-farmakoterapiya
+clinical pharmacology
-farmakogenetiks
# The half-life (T1 /2 -is indicator of:
-volume of drug distribution
-intensity biotranstransformation
+ the time for which the drug concentration in blood plasma decreases in 2 times
-elimination of constants
-volume distribution
# Almost a significant percentage of the binding of drugs to plasma proteins:
-40-60
+ 80-100
-20-40
-60-80
-15-20
# Which of these types of interaction refers to the pharmacodynamic:
+ competition for the receptor
-concuration for absorption
-concuration for binding to the protein
-concuration for the metabolism
-concuration for elimination
# The main objective of Clinical Pharmacology:
+ increasing the efficiency and safety of pharmacotherapy
-create new drugs
-improved drug supply
-improving production technology of drugs
-regulate drug products
# Drug absorption through the skin in newborns compared with adults:
-in 2-3 times less
-in 4-6 times higher
+ 2-3 times more
-in 4-6 times less
-is not different
# Adolescents (13-14 years) is recommended to prescribe drugs in doses, forming part of the adult:
+ 1/2
-1/12
-14
-3/4 the adult dose
-1-3
# Pharmacodynamics of drugs are:
+ pharmacological effects of drugs in the body
-pathway drug in the body
-effect which does not affect the therapeutic target
-changing effect under the influence of other drugs
-movement drugs in the body
# Amiodarone is indicated for:
+ WPW syndrome
-sinusovaya bradycardia
-ATP-ventricular block II Art.
-atrial fibrillation bradisistolic form
-blokada beam Hiss
# What drugs are used to normalize heart rate in atrial fibrillation?
+ propranolol, verapamil, digoxin
-lidokain, digoxin, propranolol
-adenosine, magnesium sulfate, potassium supplements
-difenin, lidocaine, potassium supplements
-hinidin, lidocaine, potassium supplements
# Which of the following drugs is used for ventricular arrhythmias caused by digitalis intoxication?
-verapamil
-amiodaron
+ lidocaine
-propafenon
-hinidin
# What antiaritmikpredochtitelnee for the treatment of sinus tachycardia in the background of angina?
-nifedipin
+ propranolol
-novokainamid
-hydrochloric potassium
-allapinin
# In patients with thyrotoxicosis paroxysmal atrial fibrillation. What medication can not be used?
-dizopiramid
-sotalol
-propranolol
+ amiodarone
-etatsizin
# In a patient with obstructive bronchitis AV tachycardia . Which is drug is contraindicated?
-diltiazem
-digoxin
+ propranolol
-amiodaron
-lidokain
# What is a side effect commonly observed in the appointment of verapamil?
-oteki legs and feet
+ bradycardia
-prilivy
-reflektornaya tachycardia
-blockade
# Which drug is the drug of choice for atrial arrhythmia in the background neurocirculatory dystonia?
-amiodaron
-verapamil
-etatsizin
+ propranolol
-hinidin
# Assignment verapamil with beta-blockers can cause:
+ reduction in myocardial contractility, bradycardia
-increasing myocardial contractility, bradycardia
-decrease in myocardial contractility, tachycardia
-increasing myocardium, tachycardia
-increasing myocardial contractility, arrhythmia
# Questions absorption, distribution, biotransformation and excretion of drugs studies
-farmakodinamika
+ pharmacokinetics
-chronofarmacology
-pharmakopeya
-pharmakogenetiks
# What determines the frequency of taking drugs?
-type drug
-path administration
+ half-life
a character of the action
-bond with proteins
# What is the drug used in the bradycardia?
-lidokain
-diltiazem
-novokainamid
+ atropine
-sotalol
#What is a drug’s half-life?
-time of maximum drug’s concentration in plasma
-time when drug reaches the systemic circulation
-timewhendrug isdistributed in the body
+time when th eplasma drug concentrationis reduced by 50%
-time when halfof the administered
dosereaches thetarget organ
#The breadthof therapeutic action- is:
-therapeutic dose ofmedication
-the ratio ofthe drug concentrationin the organ ortissue toconcentration inplasma
+range between the minimum therapeuticand minimumtoxic concentrationin plasma
-percentage ofnon-protein drugs
-the range between theminimum and maximum concentrations of the rapeutic drugs
#The receptor drugs of competitive action include:
-NSAIDs (non-steroidal anti-inflammatory drugs)
+β-adrenoblockers
-loop diuretics
- nitrates
-fluoroquinolones
#The selectivity of the drug’s action depends on:
-the half-life
-route of administration
-due to the protein
-the volume of distribution
+dose
#What drugs are more easily pass through the blood-brain barrier?
-with high solubilityin water
+with high solubilityin fats
-exhibiting properties of weakacids
-exhibiting properties ofweak bases
-loosely coupledplasma proteins
#Define a group of drugs with a narrow therapeutic index:
-β-blockers
-penicillins
+cardiac glycosides
-ACE inhibitors
-powerful diuretics
#Development of asystole is possible in combination of propranolol with:
-phenobarbital
-furosemide
+verapamil
-phenytoin
-ranitidine
#The risk of toxicity is increased in combination of gentamicin with:
+furosemide
-penicillin
-methylxanthines
-macrolides
-glucocorticoids
#To strengthen the anti-anginal effect is a combination of the most secure:
-verapamil + propranolol
-verapamil + atenolol
-verapamil + metoprolol
+verapamil +isosorbide dinitrate
-verapamil +diltiazem
#In angina pectoris the drugs of choice are following classes:
-histamine receptor’s blockers
+β-adrenergic blockers
-α-adrenergic blockers
-imidazoline receptor’s agonists
-angiotensin II receptor’s blockers
#In vasospastic angina the drugs of choice are following classes:
-histamine receptor’s blockers
-β-adrenergic blockers
-α-adrenergic blockers
+calcium channel blockers
-angiotensin II receptor’s blockers
#Adequate monitoring methods of efficacy and safety of antihypertensive therapy are:
-ECG monitoring
+BP monitoring
-one-time blood pressure measurement
-measurement of the ERF
-the dynamics of the QT interval on the electrocardiogram
#Select the unwanted effect that is not characteristic of verapamil:
-bradycardia
-constipation
-the development of AV-blockade
-swelling of legs and feet
+bronchospasm
#In treatment of hypertension the drug of first choice in patients with chronic heart failure is:
+enalapril
-verapamil
-clonidine
-prazosin
-nifedipine
#Choose the antihypertensive drug that increases the activity of sympathoadrenal system:
+nifedipine
-clonidine
-captopril
-metoprolol
-irbesartan
#In patients with hypertension combined with sinus tachycardia preference should be given to:
-calcium channel blockers of the dihydropyridine derivatives
-loop diuretics
+β-adrenergic blockers
-α-adrenergic blockers
-thiazide diuretics
#α1-adrenergic blockers are the drugs of choice for the treatment of hypertension:
-in patients with liver disease
-in patients with cardiac arrhythmias
+in older men with prostate adenoma and difficult urination
-in patients with angina pectoris
-in patients with myocardial infarction
#For the treatment of hypertension in patients with asthma cannot be used:
-calcium channel blockers
-angiotensin II receptor’s antagonists
-α
1-adrenergic blockers
+β-adrenergic blockers
-diuretics
#Patients with hypertension and myocardial infarction in the first place should be appointed:
+β-adrenergic blockers
-diuretics
-calcium channel blockers
-imidazoline receptor agonists
-α
1-adrenergic blockers
#List the group of drugs that improve the prognosis of patients with chronic heart failure:
-ACE inhibitors
-β-adrenergic blockers
-angiotensin II receptor’s blockers
-spironolactone
+mark all these drugs
#List the drugs, which have a direct positive inotropic effect:
-digoxin
-dopamine
-amrinone
-levosimendan
+mark all these drugs
#Dose titration of ACE inhibitors and β-blockers in patients with CHF includes:
-initiation of therapy with minimal doses of the drug
-increase the dose every 2 weeks
-the achievement of the target dose of the drug
-reducing the number of hospitalizations and increase a lifetimeof patient
+mark all the listed symptoms
#Principles of diuretic therapy in CHF:
-diuretics in heart failure of II-IVFC by NYHA classification
-weight loss of 0.5-1.0 kg per day
-blood pressure control
-monitoring the level of potassium in the blood
+mark all listed
#Drugs lengthening the interval QT:
-clindamycin
-amiodarone
-cotrimoxazole
-quinidine
+all
of these drugs
#List the medications prescribed for the prevention of arrhythmia in WPW-syndrome:
-digoxin
-diltiazem
+amiodarone
-procainamide
-all of the products
#Drug of choice for the treatment of paroxysmal ventricular tachycardia:
-lidocaine
-procainamide
-bretylium
-propafenone
+mark all these drugs
#Side effects of amiodarone:
-photosensitivity
-thyroid dysfunction
-dry cough
-transient increase in liver transaminases
+mark all these effects
#From selective β2-agonists is a long-acting:
-fluticasone
+salmeterol
-salbutamol
-fenoterol
-terbutaline
#Long-acting anticholinergic include:
-ipratropium bromide
-kromglikat sodium
+tiotropium bromide
-oxitropium bromide
-triamcinolone acetonide
#A side effect of inhaled corticosteroids is:
-headache
-obesity
+oral candidiasis
-diabetes
-polyuria
#The mucolytics include:
-codeine
-cromolyn sodium
+acetylcysteine
-salmeterol
-theophylline
#Drug of basic treatment in chronic obstructive bronchitis is:
+tiotropium bromide
-nedocromil sodium
-fenoterol
-montelukast
-aminophylline
#Select the group of antibacterial drugs for the treatment of infections caused by intracellular pathogens:
+macrolides
-penicillins
-aminoglycosides
-cephalosporins
-sulfonamides
#Good penetrate the blood-brain barrier following antibiotics:
-lincosamides
-macrolides
-tetracyclines
-aminoglycosides
+III generation of cephalosporins
#A preferred group of antibacterial drugs in the treatment of chronic prostatitis are:
-sulfonamides
-carbapenems
-quinolones
-linkozaminy
+fluoroquinolones
#Select the drug that most inhibits the secretion of hydrochloric acid:
-pirenzepine
-cimetidine
-misoprostol
-antacids
+omeprazole
#The maximum number of side effects among H2-blockers has:
+cimetidine
-roxatidine
-nizatidine
-ranitidine
-famotidine
#Syndrome of return caused by:
-synthetic prostaglandins
-antacids
-blockers of "proton pump"
-M-anticholinergics
+H2-blockers
#The eradication therapy to eliminate H pylori uses following antibiotic:
-carbenicillin
-erythromycin
-ceftazidime
+clarithromycin
-chloramphenicol
#Bactericidal action against H pylori has:
-sucralfate
+bismuth subcitrate
-almagelum
-famotidine
-pirenzepine
# What medications are increasingly exposed to metabolism in the liver:
+ lipophilic
-hydrophilic
- lipophobic
- having an acid reaction
- having alkaline reacting
#Preparations providing unidirectional action called:
-agonists
+synergists
-antagonists
-mimetics
-litics
#What factors affect the half-life:
+hepatic and renal clearance
-bioavailability
-velocity distribution
-communication with protein
-excretion by the kidneys
# Bioavailability - is:
-percentage of substance extracted from the organism
+the percentage of the substance has reached the systemic circulation
- the effective dose, has a therapeutic effect
- the percentage of the drug-related protein
- none of the above
#What determines the bioavailability:
-the absorption and protein link
+presystemic metabolism and absorption
-renal excretion and biotransformation in the liver
-volume of distribution
-the absorption
# The higher drug concentration in plasma when administered sublingually than orally because:
+the drug is not subject to first-pass metabolism
-the drug do not bound to plasma proteins
-the drugs do not bound to tissues
-increases the hydrophilicity of the drug
- increasing the lipophilicity of the drug
#If the effect of the two drugs is greater than the sum of the individual effects, it is called:
-antagonism
-the summary effect
-an additive effect
+potentiation
-sensitization
# What is included the concept of pharmaceutical interaction:
-displacement of the drug from binding with the protein
-inhibition of the metabolism in the liver
+inactivation of drugs in the infusion solution
-inhibition of drugs absorption
-reacting at the level of excretion in the kidney
# Indicate the disease, which reduces the binding of drugs to plasma proteins:
-ischemic heart disease
-acute infection
+liver cirrhosis
-asthma
-pneumonia
#The syndrome of "rebound" - is:
-reduction effect of the drug in its canceled
-increase the effect of the drug in its canceled
-the response of the body to cancel the drug
+development of the reverse effect with continued use of the drug
-absence of drug’s effect
# What factors reduce the absorption of drugs in the gastrointestinal tract:
-constipation
+antacids
-anticholinergics
-a good blood supply to the intestine wall
-B-blokers
# If you are using thiazide diuretics may occur:
- hyperkalemia
-gynecomastia
-Raynaud's syndrome
+gout
-hypoglycaemia
# Prescription of what vitamin during pregnancy can lead to malformations in the child:
+A
-B1
-B2
-C
-PP
# Which drug is not recommended for gout due to its ability to cause hyperuricemia:
-nitroglycerin
-erythromycin
-propranolol
+gipotiazid
-captopril
# What is a diuretic can cause the development of hirsutism and gynecomastia:
-gipotiazid
+spironolactone
-furosemide
-diakarb
-indapamide
# Which of the following drugs does not increase blood plasma atherogenicity:
-furosemide
+nifedipine
-diacarb
-gipotiazid
-propranolol
# Choose the hemodynamic effects of nifedipine:
-negative inotropic effects
-an increase in cardiac output, heart rate reduction
-increase in heart rate, dilation of venules
+an increase in heart rate, dilation of the arterioles
-a decrease in heart rate
# Which of the drugs causes a decrease in plasma renin activity:
- prazosin
-gipotiazid
-enalapril
+metoprolol
-nifedipine
# Point the factors that increase the hypotensive effect of captopril:
-low plasma’s renin activity
+giponatriyemiya
-an increasing of catecholamines
-gipernatriyemiya
-giperkaliyemiya
#The acceptance of the drug sublingual can be cut short episodes of rise in blood pressure:
+captopril
-gipotiazid
-athenolol
-ramipril
-furosemide
# Select a vasodilator, which does not cause tachycardia:
+enalapril
-prazosin
-nifedipine
-propranolol
-sodium nitroprusside
#What explains the rapid effect of furosemide intravenously for hypertensive crisis:
-diuretic effect
-natriuretic effect
+dilation of arteries and veins
-reduction in the level of renin
-activation of the RAAS
#What hypotensive agent is administered in an inactive form:
-clofelin
+enalapril
-nifedipine
-metoprolol
-captopril
# What is a side effect of -blockers which increase by combined with thiazide diuretics:
+atherogenic effect
-gipokaliyemiya
-reduction of renal function
-negative chronotropism
-negative inotropic effect
#What type of cooperation leads to the joint prescription of ramipril and hypothiazide:
-summation of effects
+potentiation
-an additive effect
-sensitization
-antagonism
#Why is the dose of verapamil inside for a sufficient hypotensive effect should be high:
+due to the pronounced first-pass metabolism
-due to the slow onset of effect
-due to the small T 1/2
-due to rapid clearance of the drug
-due to the rapid onset of effect
#The mainly due to the hypotensive effect of nifedipine:
-a decrease in cardiac output
+a decrease in peripheral vascular resistance
-a decrease in circulating blood volume
-reduction in plasma renin activity
- increase of circulating blood volume
#The antihypertensive effect of nifedipine with taking per os developed through:
+10 minutes
-30 minutes
-1 hour
-3 hours
-5 hours
# Specify a side effect that is not characteristic of captopril:
-dry cough
+hyperglycemia
-proteinuria
-neutropenia
-dyspeptic disorders
#The phenomenon of the first dose manifests with receiving of prazosin:
-short-term increase in blood pressure
+orthostatic hypotension
-a decrease in cardiac output
-a sharp increase in heart rate
-the development of arrhythmia
#What is the absolute contraindication for appointment of B-blockers:
-old age
-chronic heart insufficiency
+bronchial asthma
-impotence
-ulcer disease
#Which drug is contraindicated in hypertensive crisis with severe tachycardia:
-clonidine
-captopril
+nifedipine
-P enap
-verapamil
#Which drug should not be administered with reduced kidney function:
-fosinopril
- furosemide
-nifedipine
+gipotiazid
- amlodipine
# Why develops of tachycardia when taking arteriolar vasodilators:
-an increase in renin activity
+increased activity of sympathoadrenal
-sympatholytic effect
-cholinolytic effect
+decrease activity of sympathoadrenal
# What caused the action of losartan:
-blockade 1-receptor
-the activation of the central 2-receptor
-APF inhibition
+angiotensin receptor blockade
-the blockade of the synthesis of renin
#For what drug is not characteristic the development of orthostatic hypotension:
-clonidine
-benzogexonium
-prazosin
+amlodipine
-captopril
#What mechanism is due to additional vasodilator effect of carvedilol:
+blockade 1– receptors
-stimulation 1 - receptors
-stimulation 2-receptor
-the direct myotropic effect
-an increase in the synthesis of NO in blood vessels
#The mechanism of the antihypertensive action of perindopril is due to:
-blockade 1-receptors
-blockade B1- adrenoreceptors
-the blockade of the synthesis of renin
+the blockade of ACE
-angiotensin receptor blockade
#What is expressed in the phenomenon of "first dose" for captopril:
-violation of the peripheral circulation
-increase in heart rate
-a temporary increase in blood pressure
+hypotension
-fibrillation
#What is advisable to combine with diuretics enalapril in hypertension:
-veroshpiron
+hydrochlorothiazide
-mannitol
-triamteren
-diakarb
#The joint appointment B-blockers and oral hypoglycemic may cause:
+potentiation of the hypoglycemic action
-reduction of hypoglycemic effect
-the lack of interaction
-increase in blood pressure
-the development of arrhythmia
#Select a diuretic for stoping of hypertensive crisis:
-gipotiazid
+furosemide
-spironolactone
-triamterene
-mannitol
#Select the sublingual drug for reception in uncomplicated hypertensive crisis:
+captopril
-ramipril
-bisoprolol
-furosemide
-losartan
#Select a diuretic for long-term control of blood pressure:
-furosemide
-diakarb
+indapamide
-triamterene
-veroshpiron
#Select the rational combination of antihypertensive:
-nifedipine + B-blockers
-B-blockers + verapamil
+APF inhibitors + amlodipine
-APF inhibitor + blockers of angiotensin II receptor
- B-blockers+alfa-blokers
#Point the calcium antagonist with the longest hypotensive effect:
+amlodipine
-felodipine
-nifedipine
-diltiazem
-nifedipine-retard SR
#Specify a drug belonging to the group of direct anticoagulants:
-alteplase
-varfarin
-clopidogrel
+fraxiparine
-aspirin
#Specify a drug belonging to the group of antiplatelet agents:
-fraxiparin
+acetylsalicylic acid
-urokinase
-hirudin
-varfarin
#Specify a drug belonging to the group of thrombolytics:
-acetylsalicylic acid
+tenecteplase
-varfarin
-heparin
-fraxiparin
#What is the mechanism of action of aspirin antiplatelet:
-invertible inhibition of cyclooxygenase
-suppression of thromboxane
-blockage of glycoprotein complex IIb / IIIa
+irreversible inhibition of cyclooxygenase activity
-fibrinolysis
#Which class of drugs is fraxiparine:
-trombolitics
-antiplatelet agents
-vitamin K antagonists
+low molecular weight heparins
-statins
#Specify the mechanism of action of clopidogrel:
-blockage of COX
-blockage of receptor IIb/IIIa
+ADP receptor blockade
-blockage synthesis of clotting factors in the liver
-increase the synthesis of plasmin
#What dose aspirin should be taken in cases of suspected myocardial infarction:
-125 Mg
-250 mg
+500 Mg
-1g
-3 G
#To dissolve the fibrin clot is used:
-heparin
-aspirin
-clopidogrel
+alteplase
-clexane
#Check the effects of cardiac glycosides:
-negative chronotropic
-negative dromotropic
-negative bathmotropic
-vasodilation
+all of the above
#Specify the length of the diuretic action of hydrochlorothiazide:
-3
hours
-6 hours
+12 hours
-18 hours
-24 hours
#Why do not cause cardiac glycosides increase in myocardial oxygen consumption:
-increase the force of contraction
+the lower heart rate
-slowing of AV-conductance
-cause an increase in urine output
-improve diastolic relaxation
#What is the maximum potassium saliuretics effect?
-uregei
-furosemide
+gipotiazid
-veroshpiron
-triamterene
#What is the drug can cause hyper potassium in urea with a joint appointment with enalapril:
-digoxin
-gipotiazid
-furosemide
-prazosin
+veroshpiron
#Which of the diuretic is a competitive aldosterone antagonist?
-indapamide
-gipotiazid
-furosemide
+spironolactone
-mannitol
#Which of the cardiac glycosides has the highest bond with the protein?
-strophanthin
+digitoxin
-digoxin
-celanid
-corglicon
#Which of diuretics acting in the ascending portion of the loop of Henle?
-hypotiazid
-veroshpiron
+furosemide
-triamterene
-indapamide
#What is a diuretic can be used at a low glomerular filtration rate?
-hypotiazid
-triamterene
-spironolactone
+furosemide
- indapamide
#Specify a diuretic, which is not used in the treatment of chronic heart failure:
+mannitol
-furosemide
-gipotiazid
-spironolactone
-torasemide
#The use of what antimicrobial drugs is safe during pregnancy?
-aminoglycosides
-cotrimoxazole
-nitrofurans
+penicillins
-fluoroquinolones
#Specify the antibiotic which is the drug of choice for treatment of infections caused by methicillin-resistant staphylococcus:
-linkomycin
-erythromycin
+vancomycin
-penicillin
-oxacillin
#Is active against atypical pathogens (mycoplasma, chlamydia, legionella):
-gentamicin
+erythromycin
-ampioks
-chloramphenicol
-clindamycin
#What is the mechanism of action of bets- 2 adrenergic agonists?
-inhibition of phosphodiesterase
-inhibition of mast cell degranulation
-blockade of histamine receptors
-inhibition of the action of leukotrienes in the airways
+activation of adenylate cyclase, increased cAMP formation
# Beta-2-adrenoagonists long-acting are:
-salbutamol
-terbutaline
-fenoterol
-ortsiprenaline sulfate
+formoterol
#Specify the drug with the most potent inhibitory effect on gastric acid secretion:
+omeprazole
-cimetidine
-famotidine
-sucralfate
-pirentsipin
#The bioavailability of nifedipine is low due to:
+presistemna elimination in the liver
-low absorption
-plasma protein binding
-inactivation in the gastrointestinal tract
-accumulation in lipids
#Captopril is contraindicated in patients:
-with cirrhosis
+with chronic renal failure
-with pulmonary heart
-diabetes
-a stomach ulcer
#Specify the mechanism of action of nitroglycerin:
-adrenoceptor blockade
+antispasmodic, myotropic effect on the smooth muscle of the vascular wall
-blockage of small calcium channels of the cell membrane
-increased activity -retseptorovsosudistoy walls of the coronary arteries
-it increases the slow stream of calcium into the cell
#What are the contraindications to the use of nitrates?
-acute myocardial infarction
-arterial hypertension
+hypotension
-bradycardia
-atrioventricular block
#The antianginal effect caused by adrenoblocators?
-expansion of the coronary vessels
-decline after cardiac preload
+decrease of the heart action
-a central mechanism of action
-an increase in myocardial oxygen demand
#Specify the contraindications to nifedipine:
-hypertension
-heart failure
-bronchial asthma
+hypotension
-AV block of 2nd degree
#Specify a drug belonging to the group 1 antiarrhythmic drugs (membrane stabilizing action):
-lidocaine
-izoptine
-cordarone
+novokainamide
-difinine