The most frequent zoonosis



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tarix30.10.2017
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The most frequent zoonosis

  • The most frequent zoonosis

  • Reservoir

  • Multiple hosts

  • Species barrier

  • Epizootics and epidemics

  • Impossible to erradicate

  • Individually avoidable



Expected phenomenon

  • Expected phenomenon

  • Fast global ignition process

    • Phase 4  Phase 5  Phase 6  Portugal
  • No pandemics are alike:

  • 1889, 1900, 1918, 1957, 1968, 2009

  • Different issue from seasonal influenza

  • Emergence of the A(H1N1)2009 virus

  • H1 generations



Worldwide impact

  • Worldwide impact

    • Ongoing spread of infection over both hemispheres
    • Common trends in each hemisphere
  • National impact

    • Variable patterns according to location
    • Flu activity with up & down pattern over the weeks


Southern hemisphere

  • Southern hemisphere

    • General widespread infection, though decreasing as Winter ends
  • Northern hemisphere

    • General flu activity during all Summer
    • Japan reporting a significant increase of ILI cases


Some aspects differ from seasonal flu:

  • Some aspects differ from seasonal flu:

    • High activity during Summer, in the northern hemisphere
    • Severe and fatal cases mainly in younger age groups
    • Death mainly associated with a rapid respiratory failure
  • Very fast worldwide spreading

    • All world regions in just 9 weeks




Wide spectrum of severity (no symptoms  death)

  • Wide spectrum of severity (no symptoms  death)

    • Proportion of cases with no symptoms not yet established
  • Majority of patients develops self-limited clinical cases

  • Risk groups:

    • Pregnancy, chronic respiratory disease, cardiovascular diseases, diabetes, obesity, immunodepression.


Most patients recover without hospitalization

  • Most patients recover without hospitalization

  • Care-providers must pay attention to signs of aggravation:

    • Risk groups
    • Severe respiratory failure can develop very quickly
  • Guidelines issued on care provision and use of antivirals



Viruses remain unchanged

  • Viruses remain unchanged

    • Will evolve and diverge over time
    • Sensitive to oseltamivir and zanamivir
    • Resistant to amantadine and rimantadine
    • 12 cases of oseltamivir resistance reported
  • Increased incidence of the pandemic virus



Containment phase - April 24 – August 21

  • Containment phase - April 24 – August 21

    • First reported case - April 29
    • First secondary case - July 4
    • First cluster - July 5
    • 100 cumulative cases - July 14
    • 1000 cumulative cases – August 14
    • 2000 cumulative cases – August 21
  • Mitigation phase - August 21



Minister of Health

  • Minister of Health

  • DGS, INSA,INFARMED, INEM

  • Emergency Coordination Committee

  • Articulation with all sectors involved

  • Involvement of citizens, families and enterprises























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