Bowel/Fetal & Female Pelvis/Renal & Male Pelvis
Hall B Thursday 13:30-15:30
2659. MRI and MRS Monitoring of Gastrointestinal Distribution, Physiological Effects and Absorption of Fat Emulsions
Mahamoud Omar Hussein1, Luca Marciani2, Mary Stephenson1, Caroline L. Hoad1, Eleanor F. Cox1, Elisa Placidi1, Susan Pritchard1, Henelyta Ribeiro3, Elisabetta Ciampi3, Pip Rayment3, Asish Nandi3, Nick Hedges3, Paul Sanderson3, Irmela Kruse3, Robin C. Spiller2, Penny A. Gowland1
1The Sir Peter Mansfied Magnetic Resonance Centre, School of Physics & Astronomy, The University of Nottingham, Nottingham, NG7 2RD, United Kingdom; 2Nottingham Digestive Diseases Centre NIHR Biomedical Research Unit, The University of Nottingham, Nottingham, United Kingdom; 3Unilever Discover, Colworth Science Park, Bedford, United Kingdom
MRI can monitor gastrointestinal function and visualise the water and fat components of food in the gut separately. This study describes development work aimed to combine MRI and MRS to provide a method of monitoring the gastrointestinal fate and absorption of fat in the skeletal muscle and liver. Two healthy volunteers were fed two fat emulsions of different droplet sizes and were scanned at intervals postprandially. The 2 different meals triggered a diverse duodenal response affecting gastric emptying, gallbladder contraction and small bowel secretion. MRS showed promise for monitoring changes in both liver and calf lipid/water ratios.
2660. Validation of Automated Motion Assesment in the Abdomen
Andre M. Sprengers1, Aart J. Nederveen2, Rolf M. Lamerichs3, Jaap Stoker2
1Radiology, AMC , Amsterdam, Netherlands; 2Radiology, AMC, Amsterdam, Netherlands; 3Research, Philips, Eindhoven, Netherlands
The assessment of small bowel motility is a difficult task because of its complex nature. SPAMM or SPatial Modulation of the Magnetization is a strong candidate for a minimally invasive, observer independent method of motion assessment. The SPAMM method uses a prepulse to impose a lineshaped pattern on the magnetization. Upon readout, this pattern is distorted as a result of tissue motion between prepulse and readout. Originally developed for cardiac imaging, the SPAMM sequence was reconfigured for nonperiodic motion. The novel SPAMM technique was validated by focussing on the heartmotion, breathing motion and small bowel motility.
2661. Ultrafast Abdominal MR Imaging in Children and Young Adults with Multitransmit MR
Alisa Johnson1, Janusz Kikut1, Trevor Andrews2, Christopher G. Filippi3
1Radiology, Fletcher Allen Health Care-UVM, Burlington, VT, United States; 2MR, Philips Healthcare, Cleveland, OH, United States; 3Radiology, University of Vermont School of Medicine-Fletcher Allen Health Care, Burlington, VT, United States
The purpose of this study was to compare ultrafast imaging of the abdomen using multitransmit MR with routine, fast MR imaging in children and young adults who presented with acute abdominal pain to the emergency room.
10 patients were studied. 5 were normal, and in the other 5 patients, correct diagnoses were made. Multitransmit MR imaging quality was rated the same or better in all cases. Improvements were noted in contrast, uniformity of fluid and fat signal, and less dielectric shading. Scan times were reduced, on average, by 48%. No sedation and no oral or intravenous contrast were needed.
2662. In Vivo Trans-Pyloric Mass Movement Dynamics Measured by Means of Phase-Contrast MRI
Tobias Hahn1, Jelena Curcic1, Martin Buehrer1, Oliver Goetze2, Werner Schwizer2, Michael Fried2, Andreas Steingoetter, 1,3, Sebastian Kozerke1, Peter Boesiger1
1Institute for Biomedical Engineering, ETH and University Zurich, Zurich, Switzerland; 2Division of Gastroenterology and Hepatology, University Hospital of Zurich, Zurich, Switzerland; 3Institute of Radiology, Klinikum rechts der Isar, Technische Universität München, Munich, Germany
This study aimed for assessing the feasibility of in vivo trans-pyloric flow measurements by means of phase-contrast MRI. Dynamic EPI sequences were studied in vitro and applied in vivo behind the pylorus. The gained velocity, frequency and backflow percentage show very good agreement with literature values and give rise for expecting great potential in fast EPI phase-contrast MRI for dynamic quantification of trans-pyloric mass movements.
2663. The Impact of Abdominal Mri of Pregnant Women on Clinical and Obstetrical Management
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