Traditional Posters: Body Imaging
Yüklə 458,11 Kb.
|
| Xuedong Yang1, Ju Cao2, Xiaoying Wang1
1Department of Radiology, Peking University First Hospital, Beijing, China; 2Nephrology Department, Peking University First Hospital, Beijing, China DW and BOLD MRI can reflect changes of water diffusion and oxygen level in TIN kidney. Both methods can be used to study the TIN patients. Combined use of the two methods may aid in differentiating ATIN, CTIN from normal kidney. Medullary R2* significantly correlates with eGFR in TIN patients. 2675. Measurements of Renal Perfusion, Oxygenation, and Total Renal Blood Flow in Swine Andrew L. Wentland1,2, Nathan S. Artz1, Arjang Djamali3, Thomas M. Grist1,2, Sean B. Fain1, Elizabeth A. Sadowski2 1Medical Physics, University of Wisconsin School of Medicine & Public Health, Madison, WI, United States; 2Radiology, University of Wisconsin School of Medicine & Public Health, Madison, WI, United States; 3Nephrology, University of Wisconsin School of Medicine & Public Health, Madison, WI, United States Given the recent link between nephrogenic systemic fibrosis and gadolinium-based contrast agents (GBCAs), it has become increasingly important to evaluate techniques that operate independently of GBCAs. In this study, measurements of perfusion, oxygenation, and total renal blood flow (TRBF) were acquired in swine with arterial spin labeling-based perfusion, BOLD MRI, and phase contrast MRI, respectively. Scans were repeated during a state of increased blood flow with acetylcholine and also a state of decreased blood flow with the anesthetic isoflurane over a two-hour period. Measurements successfully demonstrated increased perfusion, oxygenation, and TRBF with acetylcholine, and the opposite trend with isoflurane. 2676. Renal-ASL Using a Multiple-Inversion Time, Free Breathing, STAR-HASTE Technique at 3T Mark Stephen Dobbs1,2, Neil Woodhouse3, Geoff J.M Parker1,2, Josephine H. Naish1,2 1Imaging Science and Biomedical Engineering, The University of Manchester, Manchester, Greater Manchester, United Kingdom; 2The University of Manchester Biomedical Imaging Institute, Manchester, Greater Manchester, United Kingdom; 3AstraZeneca, Manchester, Greater Manchester, United Kingdom ASL has been applied extensively in the brain, but there has been increasing interest in applying ASL to the kidneys, particularly as a result of concerns over the link between contrast agents and NSF. Currently, most human renal-ASL has been performed using a single inversion time, and applying a simple model for quantification. In this abstract we aim to demonstrate the feasibility of applying the Buxton model, at 3T, using a STAR based labelling technique and a free breathing approach. Here, we demonstrate the practicality of fitting for arrival time, producing high quality parametric output. 2677. Non-Invasive Investigation of Diabetic Kidney Disease by Magnetic Resonance Imaging Peter Edward Thelwall1, Roy Taylor1, Sally M. Marshall2 1Newcastle Magnetic Resonance Centre, Newcastle University, Newcastle upon Tyne, United Kingdom; 2Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom We have applied MR imaging methods to diabetic kidney disease by investigating the differences in kidney structure, blood flow and oxygenation between volunteers with Type 1 diabetes with and without diabetic nephropathy, and in non-diabetic control subjects. We hypothesised that early changes in kidney structure and function caused by diabetic nephropathy could be identified by altered renal structure, blood flow, and changes in oxygenation on water loading. Differences in renal artery flux were observed between volunteer groups. 2678. Renal Perfusion Imaging with FAIR and FIESTA at 3.0T MR Jing Wang1, Dongdong Liu2, Xuedong Yang3, Yi Dang1, Xiaoying Wang, 1,3, Jue Zhang1,2, Jing Fang1,2 1Academy for Advanced Interdisciplinary Studies, Peking University, Beijing, China; 2College of Engineering, Peking University, Beijing, China; 3Dept.of Radiology, Peking University First Hospital, Beijing, China Although Arterial Spin Labeling (ASL) being a non-invasive detection method has been used for many years, the respiratory and cardiac motions present major challenges when applying ASL. In this study, to measure the renal blood flow (RBF), a new abdominal ASL method was proposed by using single-shot fast imaging employing steady-state acquisition (FIESTA) combined with flow-sensitive alternation inversion recovery (FAIR) perfusion preparation on clinical 3.0T MR scanner. Results showed that the proposed technique had the ability to satisfy the renal perfusion quantification requirements, and the low renal perfusion area was also revealed clearly in a patient with an angioleiomyolipoma. 2679. DCE-MRI of the Kidney Using BLADE – a Feasibility Study Florian Lietzmann1, Frank G. Zöllner1, Henrik J. Michaely2, Stefan Haneder2, Ulrike Attenberger2, Lothar Rudi Schad1 1Department of Computer Assisted Clinical Medicine, Heidelberg University, Mannheim, Germany; 2Institute of Clinical Radiology and Nuclear Medicine, University Medical Center Mannheim, Mannheim, Germany Dynamic contrast enhanced MRI (DCE-MRI) provides a modern technique to assess physiological parameters like renal blood flow or glomerular filtration rate. The self-navigating BLADE-sequence with a certain robustness to motion artefacts in combination with an injection of a contrast agent offers an approach for a motion corrected DCE-examination without the need of respiratory triggering. The purpose of this study was to compare the T1-weighted BLADE sequence to the MR- gold standard TFL-sequence in clinical routine. 2680. Assessing Kidney Perfusion Using Arterial Spin Labeling and Radial Acquisition for Rapid Characterization of Inflow Dynamics Yüklə 458,11 Kb. Dostları ilə paylaş:
|