Traditional Posters: Body Imaging
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| Colleen Bailey1,2, Mostafa Atri3, Georg A. Bjarnason1, Greg J. Stanisz1,2
1Sunnybrook Health Sciences Centre, Toronto, ON, Canada; 2University of Toronto, Toronto, ON, Canada; 3University Health Network, Toronto, ON, Canada Patients with renal cell carcinoma were scanned with DCE-MRI (temporal resolution 3.7 s) and DCE-CT (temporal resolution 1 s). ROIs across the tumour volume were analyzed using the Kety-Tofts two-compartment model of perfusion. The volume transfer constant, Ktrans, did not correlate between the two modalities. The extravascular extracellular volume, ve, showed weak correlation. Undersampling the DCE-CT data to similar temporal resolution as the DCE-MRI data systematically underestimated Ktrans, whereas restricting the DCE-MRI data, initially acquired over five minutes, to the two minute acquisition time of the DCE-CT data resulted in a systematic underestimation of ve and an overestimation of Ktrans. 2689. Seminal Vesicle Dilatation in Autosomal Dominant Polycystic Kidney Disease Beatriu Reig1, Jon Blumenfeld2,3, Stephanie Donahue3, Wei Zhang, Martin R. Prince 1Department of Radiology, Weill Cornell Medical College, New York, NY, United States; 2Department of Medicine, Weill Cornell Medical College; 3The Rogosin Institute Seminal vesicle dilatation, a probable cause of infertility in men with autosomal dominant polycystic kidney disease (ADPKD), is characterized in this review of 47 male ADPKD patients undergoing MRI. Comparison is made to a cohort of age-matched controls. 2690. In Vivo Prediction of Spermatogenesis in Seminiferous Tubules Using High-Resolution Magnetic Resonance Imaging and Machine-Learning Techniques in Combination Masayuki Yamaguchi1, Natsumaro Kutsuna2,3, Ryutaro Nakagami1,4, Akira Nabetani5, Atsushi Nozaki5, Mamoru Niitsu4, Seiichiro Hasezawa2,3, Hirofumi Fujii1,3 1Functional Imaging Division, National Cancer Center Hospital East, Kashiwa, Chiba, Japan; 2Graduate School of Frontier Sciences, University of Tokyo, Kashiwa, Chiba, Japan; 3Institute for Bioinformatics Research and Development-Japan Science and Technology Agency, Chiyoda, Tokyo, Japan; 4Graduate School of Human Health Sciences, Tokyo Metropolitan University, Arakawa, Tokyo, Japan; 5GE Healthcare Japan, Hino, Tokyo, Japan Seminiferous tubules are stratified epithelia composed of germ cells and Sertoli cells. They produce sperm and normally are 200E00μm in diameter. We have succeeded in visualizing rat seminiferous tubules on in vivo MRI using a 3T scanner. In addition, the machine-learning technique allowed automatic classification of testicular regions on MRI into normal and abnormal spermatogenesis in chemotherapy-induced injury in rat testes. If these techniques are implemented in clinics in the future, they will be a helpful tool in reproductive medicine for infertile males. 2691. A Reference Region Tracer Distribution Model Analysis of Rat Penile Vascular Changes by DCE. H. Carl Le1, Nelson Bennett2, Raanan Tal2, Dov Winkleman1, John Mulhall3, Jason Koutcher1,4 1Medical Physics, MSKCC, New York, NY, United States; 2Urology, MSKCC, New York, NY, United States; 3Surgery, MSKCC, New York, NY, United States; 4Medicine, MSKCC, New York, NY, United States Sildenafil is effective in restoring penile blood flow in alleviating erectile function, a common side effect from radical prostatectomy. We have used DCE MRI to image rat corpora cavernosum post nerve injury with and without sildenafil treatment. The effect of sildenafil on the corpora cavernosal vascular volume changes are detected and can be used to monitor penile vascular health in clinic. 2692. Quality of Proton Magnetic Resonance Spectroscopic Imaging (MRSI) with and Without an Endorectal Coil: A Phantom Study Yüklə 458,11 Kb. Dostları ilə paylaş:
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