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In vitro activity of anti-malarial ozonides against an artemisinin-resistant isolate



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In vitro activity of anti-malarial ozonides against an artemisinin-resistant isolate


Recently published data suggest that artemisinin derivatives and synthetic peroxides, such as the ozonides OZ277 and OZ439, have a similar mode of action. Here the cross-resistance of OZ277 and OZ439 and four ...

Fabian Baumgärtner, Joëlle Jourdan, Christian Scheurer, Benjamin Blasco, Brice Campo, Pascal Mäser and Sergio Wittlin

Malaria Journal 2017 16:45

Efficacy of text-message reminders on paediatric malaria treatment adherence and their post-treatment return to health facilities in Kenya: a randomized controlled trial


Short Message Service (SMS) reminders have been suggested as a potential intervention for improving adherence to medications and health facility attendance.

Ambrose O. Talisuna, Amos Oburu, Sophie Githinji, Josephine Malinga, Beatrice Amboko, Philip Bejon, Caroline Jones, Robert W. Snow and Dejan Zurovac

Malaria Journal 2017 16:46

Response to fever and utilization of standby emergency treatment (SBET) for malaria in travellers to Southeast Asia: a questionnaire-based cohort study


Guidelines in several European countries recommend standby emergency treatment (SBET) for travellers to regions with low or medium malaria transmission instead of continuous chemoprophylaxis: travellers are ad...

Christof D. Vinnemeier, Camilla Rothe, Benno Kreuels, Marylyn M. Addo, Sabine Vygen-Bonnet, Jakob P. Cramer and Thierry Rolling

Malaria Journal 2017 16:44

On the cytokine/chemokine network during Plasmodium vivax malaria: new insights to understand the disease


The clinical outcome of malaria depends on the delicate balance between pro-inflammatory and immunomodulatory cytokine responses triggered during infection. Despite the numerous reports on characterization of ...

Natália Satchiko Hojo-Souza, Dhelio Batista Pereira, Fernanda Sumika Hojo de Souza, Tiago Antônio de Oliveira Mendes, Mariana Santos Cardoso, Mauro Shugiro Tada, Graziela Maria Zanini, Daniella Castanheira Bartholomeu, Ricardo Toshio Fujiwara and Lilian Lacerda Bueno

Malaria Journal 2017 16:42

Optimization of mosquito egg production under mass rearing setting: effects of cage volume, blood meal source and adult population density for the malaria vector, Anopheles arabiensis


Anopheles arabiensis is one of the major malaria vectors that put millions of people in endemic countries at risk. Mass-rearing of this mosquito is crucial for strategies that use ster...

Wadaka Mamai, Nanwintoum S. Bimbile-Somda, Hamidou Maiga, José Guillermo Juarez, Zaynab A. I. Muosa, Adel Barakat Ali, Rosemary Susan Lees and Jeremie R. L. Gilles

Malaria Journal 2017 16:41

Recent uptake of intermittent preventive treatment during pregnancy with sulfadoxine–pyrimethamine is associated with increased prevalence of Pfdhfr mutations in Bobo-Dioulasso, Burkina Faso


The impact of sulfadoxine–pyrimethamine (SP) used as intermittent preventive treatment during pregnancy (IPTp-SP) on mutant parasite selection has been poorly documented in Burkina Faso. This study sought firs...

Mamoudou Cisse, Gordon A. Awandare, Alamissa Soulama, Halidou Tinto, Marie-Pierre Hayette and Robert T. Guiguemdé

Malaria Journal 2017 16:38

A(maize)ing attraction: gravid Anopheles arabiensis are attracted and oviposit in response to maize pollen odours


Maize cultivation contributes to the prevalence of malaria mosquitoes and exacerbates malaria transmission in sub-Saharan Africa. The pollen from maize serves as an important larval food source for Anopheles mosq...

Betelehem Wondwosen, Sharon R. Hill, Göran Birgersson, Emiru Seyoum, Habte Tekie and Rickard Ignell

Malaria Journal 2017 16:39

Health worker adherence to malaria treatment guidelines at outpatient health facilities in southern Malawi following implementation of universal access to diagnostic testing


Appropriate diagnosis and treatment are essential for reducing malaria mortality. A cross-sectional outpatient health facility (HF) survey was conducted in southern Malawi from January to March 2015 to determi...

Ruth J. Namuyinga, Dyson Mwandama, Dubulao Moyo, Austin Gumbo, Peter Troell, Miwako Kobayashi, Monica Shah, Andrew Bauleni, Jodi Vanden Eng, Alexander K. Rowe, Don P. Mathanga and Laura C. Steinhardt

Malaria Journal 2017 16:40

Development of Plasmodium falciparum specific naïve, atypical, memory and plasma B cells during infancy and in adults in an endemic area


B-cells are essential in immunity against malaria, but which sub-sets of B-cells specifically recognize Plasmodium falciparum and when they appear is still largely unknown.

Allan Lugaajju, Sreenivasulu B. Reddy, Mats Wahlgren, Fred Kironde and Kristina E. M. Persson

Malaria Journal 2017 16:37

Performance of loop-mediated isothermal amplification (LAMP) for the diagnosis of malaria among malaria suspected pregnant women in Northwest Ethiopia


Malaria is a major public health problem and an important cause of maternal and infant morbidity in sub-Saharan Africa, including Ethiopia. Early and accurate diagnosis of malaria with effective treatment is t...

Banchamlak Tegegne, Sisay Getie, Wossenseged Lemma, Abu Naser Mohon and Dylan R. Pillai

Malaria Journal 2017 16:34

Heterogeneity of G6PD deficiency prevalence in Mozambique: a school-based cross-sectional survey in three different regions


Glucose-6-phosphate dehydrogenase (G6PD) deficiency is an X-linked hereditary enzymatic abnormality that affects more than 400 million people worldwide. Most deficient individuals do not manifest any symptoms;...

Beatriz Galatas, Lurdes Mabote, Wilson Simone, Gloria Matambisso, Lidia Nhamussua, María del Mar Mañú-Pereira, Clara Menéndez, Francisco Saute, Eusebio Macete, Quique Bassat, Pedro Alonso and Pedro Aide

Malaria Journal 2017 16:36


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