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Malaria epidemiological research in the Republic of Congo



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Malaria epidemiological research in the Republic of Congo


Reliable and comprehensive information on the burden of malaria is critical for guiding national and international efforts in malaria control. The purpose of this review is to provide an overview of published ...

Felix Koukouikila-Koussounda and Francine Ntoumi

Malaria Journal 2016 15:598

Whole genome sequencing of Plasmodium falciparum from dried blood spots using selective whole genome amplification


Translating genomic technologies into healthcare applications for the malaria parasite Plasmodium falciparum has been limited by the technical and logistical difficulties of obtaining high quality clinical sample...

Samuel O. Oyola, Cristina V. Ariani, William L. Hamilton, Mihir Kekre, Lucas N. Amenga-Etego, Anita Ghansah, Gavin G. Rutledge, Seth Redmond, Magnus Manske, Dushyanth Jyothi, Chris G. Jacob, Thomas D. Otto, Kirk Rockett, Chris I. Newbold, Matthew Berriman and Dominic P. Kwiatkowski

Malaria Journal 2016 15:597

Genetic evidence that the Makira region in northeastern Madagascar is a hotspot of malaria transmission


Encouraging advances in the control of Plasmodium falciparum malaria have been observed across much of Africa in the past decade. However, regions of high relative prevalence and transmission that remain unaddres...

Benjamin L. Rice, Christopher D. Golden, Evelin Jean Gasta Anjaranirina, Carolina Mastella Botelho, Sarah K. Volkman and Daniel L. Hartl

Malaria Journal 2016 15:596

Spatial and space–time distribution of Plasmodium vivax and Plasmodium falciparum malaria in China, 2005–2014


Despite the declining burden of malaria in China, the disease remains a significant public health problem with periodic outbreaks and spatial variation across the country. A better understanding of the spatial...

Samuel H. Hundessa, Gail Williams, Shanshan Li, Jinpeng Guo, Linping Chen, Wenyi Zhang and Yuming Guo

Malaria Journal 2016 15:595

Using an intervention mapping approach for planning, implementing and assessing a community-led project towards malaria elimination in the Eastern Province of Rwanda


Active community participation in malaria control is key to achieving malaria pre-elimination in Rwanda. This paper describes development, implementation and evaluation of a community-based malaria elimination...

Chantal Marie Ingabire, Emmanuel Hakizimana, Fredrick Kateera, Alexis Rulisa, Bart Van Den Borne, Ingmar Nieuwold, Claude Muvunyi, Constantianus J. M. Koenraadt, Michele Van Vugt, Leon Mutesa and Jane Alaii

Malaria Journal 2016 15:594

The economics of malaria control and elimination: a systematic review


Declining donor funding and competing health priorities threaten the sustainability of malaria programmes. Elucidating the cost and benefits of continued investments in malaria could encourage sustained politi...

Rima Shretta, Anton L. V. Avanceña and Arian Hatefi

Malaria Journal 2016 15:593

Plasmodium falciparum genotype and gametocyte prevalence in children with uncomplicated malaria in coastal Ghana


Plasmodium falciparum gametocytes are vital to sustaining malaria transmission. Parasite densities, multiplicity of infection as well as asexual genotype are features that have been fo...

Ruth Ayanful-Torgby, Akua Oppong, Joana Abankwa, Festus Acquah, Kimberly C. Williamson and Linda Eva Amoah

Malaria Journal 2016 15:592

A national health facility survey of malaria infection among febrile patients in Kenya, 2014


The use of malaria infection prevalence among febrile patients at clinics has a potential to be a valuable epidemiological surveillance tool. However, routine data are incomplete and not all fevers are tested....

Sophie Githinji, Abdisalan M. Noor, Josephine Malinga, Peter M. Macharia, Rebecca Kiptui, Ahmeddin Omar, Kiambo Njagi, Ejersa Waqo and Robert W. Snow

Malaria Journal 2016 15:591

Culex pipiens forms and urbanization: effects on blood feeding sources and transmission of avian Plasmodium


The wide spread mosquito Culex pipiens pipiens have two forms molestus and pipiens which frequently hybridize. The two forms have behavioural and physiological differences affecting habitat requirements and host ...

Josué Martínez-de la Puente, Martina Ferraguti, Santiago Ruiz, David Roiz, Ramón C. Soriguer and Jordi Figuerola

Malaria Journal 2016 15:589

Patterns and determinants of malaria risk in urban and peri-urban areas of Blantyre, Malawi


Although malaria disease in urban and peri-urban areas of sub-Saharan Africa is a growing concern, the epidemiologic patterns and drivers of transmission in these settings remain poorly understood. Factors ass...

Don P. Mathanga, Atupele Kapito Tembo, Themba Mzilahowa, Andy Bauleni, Kondwani Mtimaukenena, Terrie E. Taylor, Clarissa Valim, Edward D. Walker and Mark L. Wilson

Malaria Journal 2016 15:590

Cytochrome P450 2D-mediated metabolism is not necessary for tafenoquine and primaquine to eradicate the erythrocytic stages of Plasmodium berghei


Due to the ability of the 8-aminoquinolines (8AQs) to kill different stages of the malaria parasite, primaquine (PQ) and tafenoquine (TQ) are vital for causal prophylaxis and the eradication of erythrocytic Plasm...

Erin E. Milner, Jonathan Berman, Diana Caridha, Samuel P. Dickson, Mark Hickman, Patricia J. Lee, Sean R. Marcsisin, Lisa T. Read, Norma Roncal, Brian A. Vesely, Lisa H. Xie, Jing Zhang, Ping Zhang and Qigui Li

Malaria Journal 2016 15:588

Economic evaluation of artesunate and three quinine regimens in the treatment of severe malaria in children at the Ebolowa Regional Hospital-Cameroon: a cost analysis


Severe malaria is a leading cause of morbidity and mortality in under-fives in sub-Saharan Africa. Recently quinine has been replaced by artesunate as the first-line drug in the treatment of severe malaria in ...

Daniel Ethe Maka, Andreas Chiabi, Bolaji Obadeyi, Evelyn Mah, Séraphin Nguefack, Pamela Nana, Wilfred Mbacham and Elie Mbonda

Malaria Journal 2016 15:587


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