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Health worker and policy-maker perspectives on use of intramuscular artesunate for pre-referral and definitive treatment of severe malaria at health posts in Ethiopia



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Health worker and policy-maker perspectives on use of intramuscular artesunate for pre-referral and definitive treatment of severe malaria at health posts in Ethiopia


The World Health Organization (WHO) recommends injectable artesunate given either intravenously or by the intramuscular route for definitive treatment for severe malaria and recommends a single intramuscular d...

Takele Kefyalew, Zelalem Kebede, Dawit Getachew, David Mukanga, Tessema Awano, Agonafer Tekalegne, Esey Batisso, Wasihun Edossa, Emebet Mekonnen, James Tibenderana, Ebenezer Sheshi Baba, Constance Shumba, Joaniter I. Nankabirwa and Prudence Hamade

Malaria Journal 2016 15:507

Household clustering of asymptomatic malaria infections in Xepon district, Savannakhet province, Lao PDR


In the Lao PDR, malaria morbidity and mortality have remarkably decreased over the past decade. However, asymptomatic infections in rural villages contribute to the on-going local transmission. The primary obj...

Tiengkham Pongvongsa, Daisuke Nonaka, Moritoshi Iwagami, Masami Nakatsu, Panom Phongmany, Futoshi Nishimoto, Jun Kobayashi, Bouasy Hongvanthon, Paul T. Brey, Kazuhiko Moji, Toshihiro Mita and Shigeyuki Kano

Malaria Journal 2016 15:508

The effectiveness of a nationwide universal coverage campaign of insecticide-treated bed nets on childhood malaria in Malawi


Although the universal coverage campaign of insecticide-treated mosquito bed nets (ITNs) has been associated with improved malaria outcomes, recent reports indicate that the campaign is losing its sparkle in s...

Collins O. F. Zamawe, Kanan Nakamura, Akira Shibanuma and Masamine Jimba

Malaria Journal 2016 15:505

Malaria investigation and treatment of children admitted to county hospitals in western Kenya


Up to 90 % of the global burden of malaria morbidity and mortality occurs in sub-Saharan Africa and children under-five bear a disproportionately high malaria burden. Effective inpatient case management can re...

Beatrice I. Amboko, Philip Ayieko, Morris Ogero, Thomas Julius, Grace Irimu and Mike English

Malaria Journal 2016 15:506.

Contemporary epidemiological overview of malaria in Madagascar: operational utility of reported routine case data for malaria control planning


Malaria remains a major public health problem in Madagascar. Widespread scale-up of intervention coverage has led to substantial reductions in case numbers since 2000. However, political instability since 2009...

Rosalind E. Howes, Sedera Aurélien Mioramalala, Brune Ramiranirina, Thierry Franchard, Andry Joeliarijaona Rakotorahalahy, Donal Bisanzio, Peter W. Gething, Peter A. Zimmerman and Arsène Ratsimbasoa

Malaria Journal 2016 15:502

Size polymorphism and low sequence diversity in the locus encoding the Plasmodium vivax rhoptry neck protein 4 (PvRON4) in Colombian isolates


Designing a vaccine against Plasmodium vivax has focused on selecting antigens involved in invasion mechanisms that must have domains with low polymorphism for avoiding allele-specific immune responses. The rhopt...

Sindy P. Buitrago, Diego Garzón-Ospina and Manuel A. Patarroyo

Malaria Journal 2016 15:501

Communication for behavioural impact in enhancing utilization of insecticide-treated bed nets among mothers of under-five children in rural North Sudan: an experimental study


Malaria is the leading cause of morbidity and mortality in Sudan. The entire population is at risk of contracting malaria to different levels. This study aimed to assess the effectiveness of communication for ...

Yousif Mohammed Elmosaad, Magda Elhadi, Asif Khan, Elfatih Mohamed Malik and Ilias Mahmud

Malaria Journal 2016 15:509

Therapeutic efficacy of artemether–lumefantrine for the treatment of uncomplicated Plasmodium falciparum malaria from three highly malarious states in India


Anti-malarial drug resistance continues to be a leading threat to malaria control efforts and calls for continued monitoring of waning efficacy of artemisinin-based combination therapy (ACT). Artesunate + sulf...

Praveen K. Bharti, Man M. Shukla, Pascal Ringwald, Sri Krishna, Pushpendra P. Singh, Ajay Yadav, Sweta Mishra, Usha Gahlot, Jai P. Malaiya, Amit Kumar, Shambhu Prasad, Pradeep Baghel, Mohan Singh, Jaiprakash Vadadi, Mrigendra P. Singh, Maria Dorina G. Bustos…

Malaria Journal 2016 15:498

Timing of in utero malaria exposure influences fetal CD4 T cell regulatory versus effector differentiation


In malaria-endemic areas, the first exposure to malaria antigens often occurs in utero when the fetal immune system is poised towards the development of tolerance. Children exposed to placental malaria have an...

Mary Prahl, Prasanna Jagannathan, Tara I. McIntyre, Ann Auma, Lila Farrington, Samuel Wamala, Mayimuna Nalubega, Kenneth Musinguzi, Kate Naluwu, Esther Sikyoma, Rachel Budker, Hilary Vance, Pamela Odorizzi, Patience Nayebare, John Ategeka, Abel Kakuru…

Malaria Journal 2016 15:497

Performance and time to become negative after treatment of three malaria rapid diagnostic tests in low and high malaria transmission settings


The performance of different malaria rapid diagnostic tests (RDT) may be influenced by transmission intensity and by the length of time each test requires to become negative after treatment and patient’s recov...

Francesco Grandesso, Carolyn Nabasumba, Dan Nyehangane, Anne-Laure Page, Mathieu Bastard, Martin De Smet, Yap Boum and Jean-François Etard


Erratum to: Glucagon-like peptide-1 analogue, liraglutide, in experimental cerebral malaria: implications for the role of oxidative stress in cerebral malaria


Brian DellaValle, Casper Hempel, Trine Staalsoe, Flemming Fryd Johansen and Jørgen Anders Lindholm Kurtzhals

Malaria Journal 2016 15:495



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