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Health workers’ compliance to rapid diagnostic tests (RDTs) to guide malaria treatment: a systematic review and meta-analysis



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Health workers’ compliance to rapid diagnostic tests (RDTs) to guide malaria treatment: a systematic review and meta-analysis


The World Health Organization recommends malaria to be confirmed by either microscopy or a rapid diagnostic test (RDT) before treatment. The correct use of RDTs in resource-limited settings facilitates basing ...

Alinune N. Kabaghe, Benjamin J. Visser, Rene Spijker, Kamija S. Phiri, Martin P. Grobusch and Michèle van Vugt

Malaria Journal 2016 15:163

There is no free here, you have to pay”: actual and perceived costs as barriers to intermittent preventive treatment of malaria in pregnancy in Mali


“There is no free here,” the words of a Malian husband, illustrate how perceptions of cost can deter uptake of intermittent preventive treatment of malaria in pregnancy (IPTp). The Malian Ministry of Health (M...

Meredith C. Klein, Steven A. Harvey, Hawa Diarra, Emily A. Hurley, Namratha Rao, Samba Diop and Seydou Doumbia

Malaria Journal 2016 15:158

Genetic diversity of Plasmodium falciparum isolates from concurrent malaria and arbovirus co-infections in Kedougou, southeastern Senegal


Concurrent malaria and arbovirus infections are common and represent an important public health concern in regions where both diseases are endemic. The present study investigates the genetic diversity and comp...

Makhtar Niang, Cheikh Loucoubar, Abdourahmane Sow, Moussa Moise Diagne, Oumar Faye, Ousmane Faye, Mawlouth Diallo, Aissatou Toure-Balde and Amadou A. Sall

Malaria Journal 2016 15:155

Plasmodium falciparum parasitaemia and clinical malaria among school children living in a high transmission setting in western Kenya


Malaria among school children is increasingly receiving attention, yet the burden of malaria in this age group is poorly defined. This study presents data on malaria morbidity among school children in Bungoma ...

Stella Kepha, Birgit Nikolay, Fred Nuwaha, Charles S. Mwandawiro, Joaniter Nankabirwa, Juliet Ndibazza, Jorge Cano, Damaris Matoke-Muhia, Rachel L. Pullan, Elizabeth Allen, Katherine E. Halliday and Simon J. Brooker

Malaria Journal 2016 15:157

A method to preserve low parasitaemia Plasmodium-infected avian blood for host and vector infectivity assays


Avian malaria vector competence studies are needed to understand more succinctly complex avian parasite-vector-relations. The lack of vector competence trials may be attributed to the difficulty of obtaining g...

Jenny S. Carlson, Federico Giannitti, Gediminas Valkiūnas, Lisa A. Tell, Joy Snipes, Stan Wright and Anthony J. Cornel

Malaria Journal 2016 15:154

Endogenously-expressed NH2-terminus of circumsporozoite protein interferes with sporozoite invasion of mosquito salivary glands


The circumsporozoite protein is the most abundant polypeptide expressed by sporozoites, the malaria parasite stage capable of infecting humans. Sporozoite invasion of mosquito salivary glands prior to transmis...

Bianca B. Kojin, André Luis Costa-da-Silva, Ceres Maciel, Dayane Alves Henriques, Danilo O. Carvalho, Kelcie Martin, Osvaldo Marinotti, Anthony A. James, Myrna C. Bonaldo and Margareth Lara Capurro

Malaria Journal 2016 15:153

Determinants of host feeding success by Anopheles farauti


The proportion of blood meals that mosquitoes take from a host species is a function of the interplay of extrinsic (abundance and location of potential hosts) and intrinsic (innate preference) factors. A mark-...

Tanya L. Russell, Nigel W. Beebe, Hugo Bugoro, Allan Apairamo, Robert D. Cooper, Frank H. Collins, Neil F. Lobo and Thomas R. Burkot

Malaria Journal 2016 15:152

Frequent blood feeding enables insecticide-treated nets to reduce transmission by mosquitoes that bite predominately outdoors


The effectiveness of vector control on malaria transmission by long-lasting insecticidal nets (LLINs) and indoor residual spraying (IRS) depends on the vectors entering houses to blood feed and rest when peopl...

Tanya L. Russell, Nigel W. Beebe, Hugo Bugoro, Allan Apairamo, Weng K. Chow, Robert D. Cooper, Frank H. Collins, Neil F. Lobo and Thomas R. Burkot

Malaria Journal 2016 15:156

Anopheles farauti is a homogeneous population that blood feeds early and outdoors in the Solomon Islands


In the 1970s, Anopheles farauti in the Solomon Island responded to indoor residual spraying with DDT by increasingly feeding more outdoors and earlier in the evening. Although long-lasting insecticidal nets (LLIN...

Tanya L. Russell, Nigel W. Beebe, Hugo Bugoro, Allan Apairamo, Frank H. Collins, Robert D. Cooper, Neil F. Lobo and Thomas R. Burkot

Malaria Journal 2016 15:151

Expression of complement and toll-like receptor pathway genes is associated with malaria severity in Mali: a pilot case control study


The host response to infection by Plasmodium falciparum, the parasite most often responsible for severe malaria, ranges from asymptomatic parasitaemia to death. The clinical trajectory of malaria is influenced by...

Rafal S. Sobota, Antoine Dara, Jessica E. Manning, Amadou Niangaly, Jason A. Bailey,Abdoulaye K. Kone, Mahamadou A. Thera, Abdoulaye A. Djimdé, Guy Vernet, Philippe Leissner, Scott M. Williams, Christopher V. Plowe and Ogobara K. Doumbo

Malaria Journal 2016 15:150

Operational strategies of anti-malarial drug campaigns for malaria elimination in Zambia’s southern province: a simulation study


Malaria elimination requires reducing both the potential of mosquitoes to transmit parasites to humans and humans to transmit parasites to mosquitoes. To achieve this goal in Southern province, Zambia a mass t...

Erin M. Stuckey, John M. Miller, Megan Littrell, Nakul Chitnis and Rick Steketee

Malaria Journal 2016 15:148


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