Executive Summary


Design an Expertise Platform on Lipidomics



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Design an Expertise Platform on Lipidomics

  • Hold a survey of expertise and infrastructure with the Lipidomics field



    Description of the Lipidomics Expertise Platform (LEP)

    The Lipidomics Expertise Platform (LEP, http://www.lipidomics-expertise.de) was set up in 2005 (Fig. 1).



    Fig. 1: Starting page and menu structure of the LEP


    In order to gain full access institutions and users have to register with the LEP. Currently, 128 different scientific and 6 industrial institutions are registered in the LEP. These institutions include a total number of 188 registered users. Most users belong to 18 different European countries, although there are non-European registrations from 8 countries (Table 1). The contact details of institutions and user registered in LEP are attached in appendices 1 and 3, respectively.



    Europe



















    Users

    Institutions

    Country

    scientific

    industrial

    scientific

    industrial

    Austria

    10

    1

    8

    1

    Belgium

    4

     

    4

     

    Denmark

    1

     

    1

     

    Finland

    6

     

    6

     

    France

    21

    1

    14

    1

    Germany

    33

     

    24

     

    Greece

    1

     

    1

     

    Hungary

    7

     

    4

     

    Italy

    14

     

    9

     

    Netherlands

    21

    2

    7

    2

    Norway

    1

    1

    1

    1

    Poland

    1

     

    1

     

    Romania

    1

     

    1

     

    Slovenia

    1

     

    1

     

    Spain

    10

     

    7

     

    Sweden

    5

     

    3

     

    Switzerland

    4

     

    2

     

    United Kingdom

    22

    1

    16

    1

    Total

    163

    6

    110

    6
















    Non European Countries



















    User

    Institutions

    Country

    scientific

    industrial

    scientific

    industrial

    Argentina

    2

     

    1

     

    Brazil

    1

     

    1

     

    Canada

    2

     

    2

     

    China

    1

     

    1

     

    Israel

    1

     

    1

     

    Japan

    3

     

    2

     

    Taiwan

    3

     

    2

     

    United States

    12

     

    8

     

    Total

    25

    0

    18

    0

    Table 1: Users and Institutions registered in the LEP (as at 01.01.2008)
    One aim of the Lipidomics Expertise Platform was to collect and provide information on labs involved in lipidomics. Therefore the LEP contains various electronic surveys that collect contact information and give an overview of the expertise present in the various labs. The institutions registered were asked to complete electronic surveys on (Fig. 2):


    Fig. 2: Wizard for electronic surveys


    Fig. 3: Search menu for lipidomics expertise.


    The results of these surveys are searchable in an advanced search menu (Fig. 3). A statistical analysis of the survey results is shown in Table 2-5. Detailed survey results are displayed in appendix 2 ordered by country.



    Areas of Lipidomics Expertise

    Lipid Metabolism

    37

    Analytical Tools in Lipidomics

    36

    Lipid Signalling

    23

    Membrane Microdomains

    22

    Mapping of the Lipidome

    19

    Genomics of the Lipidome

    19

    Lipids in Inflammation

    19

    Metabolomics of the Lipidome

    18

    Membrane Trafficking

    18

    Lipid Transport

    17

    Lipids and Nutrition

    17

    Signalomics of the Lipidome

    11

    Bioinformatics related to the Lipidome

    10

    Proteomics of the Lipidome

    9

    Pharmacology and toxicology of the Lipidome

    8

    Glycomics of the Lipidome

    7

    Lipids in Microbiology

    7

    Chemical Synthesis of Lipids (Probes/Tools/Agents)

    7

    Lipid Standard Bank

    7

    Nutrigenomics of the Lipidome

    6

    Lipids in Skin Care

    2

    Table 2: Survey on the areas of Lipidomics expertise; Institutions with medium and high expertise level


    Lipid Class - Survey

    Fatty Acids and Conjugates [FA01]

    24

    Glycerophosphocholines [GP01]

    21

    Glycerophosphoethanolamines [GP02]

    17

    Eicosanoids [FA03]

    13

    Ceramides [SP02]

    13

    Diradylglycerols [GL02]

    12

    Glycerophosphoglycerols [GP04]

    11

    Docosanoids [FA04]

    8

    Glycerophosphoglycerophosphates [GP05]

    7

    Glycerophosphates [GP10]

    7

    Fatty aldehydes [FA06]

    6

    Fatty esters [FA07]

    6

    Triradylglycerols [GL03]

    5

    Phosphosphingolipids [SP03]

    5

    Neutral glycosphingolipids [SP05]

    5

    Sterols [ST01]

    5

    Glycerophosphoserines [GP03]

    4

    Glycerophosphoinositols [GP06]

    4

    Glycerophosphoinositol bisphosphates [GP08]

    4

    Acidic glycosphingolipids [SP06]

    4

    Bile acids and derivatives [ST04]

    4

    Glycerophosphoinositol monophosphates [GP07]

    3

    Steroids [ST02]

    3

    Table 3: Survey on lipid classes investigated; Institutions with medium and high expertise level (only lipids classes with more than 2 hits)



    Technology - Survey

    ESI

    32

    Fluorescence Microscopy

    27

    Enzymatic Assays

    27

    LC

    24

    GC

    23

    Gel Electrophoresis

    22

    Light Microscopy

    19

    CI

    18

    Confocal Microscopy

    18

    LC-MS coupling

    17

    NCI

    15

    Thin layer chromatography

    14

    Normal Phase

    14

    GC-MS coupling

    14

    Real Time PCR

    14

    Reversed Phase

    13

    Ion Exchange

    13

    Liquid-Liquid Extraction

    13

    Cell Sorting

    13

    Immuno Assays

    13

    DNA Sequencing

    12

    Data Processing

    11

    EI

    9

    Quadrupole

    9

    Ion Trap

    9

    Database Setup

    9

    Cluster Analysis

    9

    Biostatistics

    9

    Immune Affinity

    8

    MALDI

    8

    Solid Phase Extraction

    7

    Microarrays

    7

    Chemical Synthesis

    7

    Size Exclusion

    6

    nano ESI

    6

    APCI

    6

    Electron Microscopy

    6

    Nuclear Magnetic Resonance

    6

    Multicolor Analysis

    5

    UV-Vis Spectroscopy

    5

    TOF

    4

    Electron Spin Resonance

    4

    Infrared Spectroscopy

    4

    Fluorescence Phosphorescence Spectroscopy

    4

    Capillary Electrophoresis

    3

    FTICR

    3

    QqTOF

    3

    Atomic Force

    3

    Capillary Electrophoresis

    3

    dHPLC

    3


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