Curriculum vitae personal information

CURRICULUM VITAE
PERSONAL INFORMATION:
Full Name: Nagarajan Pattabiraman Ph. D.
Office Address: Room W-224A

Departments of Oncology &

Biochemistry & Molecular Biology

Lombardi Cancer Center

3970 Reservoir Road, NW

Georgetown University

Box 571469

Washington DC 20057-1469

Office Telephone Number: [phone]

Fax: [phone]

E-mail: [e-mail]


EDUCATION:
Tagore Arts College,

Pondicherry, India,

1969-1972, B. Sc.
Presidency College,

Madras, India,

1972-1974, M. Sc.
Indian Institute of Science,
Bangalore, India,
1974-1979, Ph. D.

(Thesis Advisor: Professor V. Sasisekharan)

POSITIONS and EMPLOYMENT

Associate Professor- Department of Oncology, Lombardi Cancer Center, Georgetown University, Washington DC 20007 Jul, 2002-present.

Scientist - AstraZeneca Inc., 1800 Concord Pike, Wilmington, DE-19850, 2001 - 2002
Scientific Applications Analyst - Advanced Biomedical Computing Center, SAIC, NCI-Frederick Cancer Center, Frederick, MD 21702, 1993 - 2001,

Adjunct Associate Professor - Department of Biochemistry & Molecular Biology, Georgetown University, Washington D. C. 20007, 1993 - 1995,

Senior Scientist - Geo-Centers, Laboratory of Structure of Matter, Naval Research Laboratory, Washington D. C, 1987 - 1993
Assistant Research Chemist - Department of Pharmaceutical Chemistry, University of California, San Francisco, CA-94143, 1984 - 1987
Post-Graduate Research Chemist - Department of Pharmaceutical Chemistry, University of California, San Francisco, CA-94143, 1981 - 1984
Research Associate - Molecular Biophysics Unit, Indian Institute of Science, Bangalore-560 012, India, 1980 - 1981
HONORS AND AWARDS:
2003 Severed as a panel member of The Presidential Awards for Excellence in Mathematics and Science Teaching (PAEMST) Program Committee, sponsored by the National Science Foundation (NSF).

1999 Norman P. Salzman Mentoring Award (carries a Plaque and a cash award).

"In Recognition of a devoted scientist for his lifetime commitment to the guidance and direction of others in the pursuit of scientific excellence"

1985 Who's Who in Frontiers of Science and Technology (2nd Ed.)

1980 Indian National Science Academy Young Scientist Award, India

Kothari Scientific and Research Institute Cash Awards, India

1978-1979 Senior Research Fellowship from Indian Institute of Science, India

1974-1978 Junior Research Fellowship from UGC, New Delhi, India

1974 Dr. H. Parameswarn Memorial Senior Prize

Sitalakshmi Subramaniya Prize

Jones Memorial Senior Prize

The Dr. K. S. Krishnan Gold Medal

The Jagirdar of Arni Medal I

The Professor P. E. S. Ayyar Commenmoration Medal

The Dr. K. S. Krishnan Memorial Prize

The Madras University Centenary Delhi Prize

1968-1974 Post-Matric Merit Scholarship of Government of Pondicherry, India
PROFESSIONAL SOCIETIES:
Indian Biophysical Society (Life Member)

QSAR and Modeling Society

Molecular Graphics and Modeling Society

PUBLIC SERVICE:
Journal Reviews:
Biopolymers, Journal of Molecular Graphics, Journal of Biomolecular Structure and Dynamics and Medicinal Chemistry Research
Grant Review:
Special Study Section, Division of Research Grants, NIH

Conferences:
Co-chaired the session on "Structural Biology of Uteroglobin/CC10kDa protein & UG-Derived Bioactive peptides" in the "Uteroglobin/Clara Cell 10kDa family of proteins", April 14-16, 2000 held at Bethesda by the New York Academy of Sciences. Member of the Nomenclature committee for Uteroglobin/Clara Cell 10kDa family of proteins.
Invited participant at the “RNA Informatics Workshop” held at NSF, Arlington, VA, December 8-11, 1998 by the RNA society.
Chaired a session on “Molecular Visualization of Macromolecules” at the Molecular Graphics Conference held at Bethesda, April 1985.

Other Activities:

Supervised a summer student, Advanced Biomedical Computing Center,

Frederick, MD, 1995-1998.
Served as a member of the Master's Committee for Alan Doss, Department of Biomedical Sciences, Graduate School of Hood College, Frederick, MD, 2000.
From 1997-2001, I coordinated 20 week Hands-on Science Program on Saturday "Adventure in Science" for Children ages from 8 to 15 at Frederick and at COMSAT, MD.
From 1993-2001, involved in the "Take your Kid to Work" program at NCI,

Frederick, MD.

Supervised a M. S. biotocology student intern for a semester (Fall-02)

Departmnet of Biochemistry and Molecular Biology, Georgetown University

Medical Center.
Severed as a panel member for the Presidential Awards for Excellence

in Mathematics and Science Teaching Committee - 2003

INVITED TALKS/SEMINARS:
Invited talk at the Atlantic Symposium on Computational Biology, Genome Information Systems & Technology, March 15, 16 & 17, 2001,Regal University Center, Durham, N.C., USA. The title of the talk was "Computational Methods in the Analysis of Ligand-Macromolecule Contacts"
Invited talk at the "RNA Informactics Workshop" held at NSF, Arlington, VA December 8-11 1998 by the RNA society. The title of the talk was "Antibiotics-RNA interactions"
Invited talk at the International Conference on "Structures, Conformations and Interactions of Nucleic Acids" held at National Institutes of Health, Bethesda, Maryland, November 18-20, 1992. The title of the talk was "Parallel Stranded Nucleic Acid Structures: A Theoretical Study"
Invited seminar at CETUS, Berkely, CA,"Application of Computer Graphics to Molecular Modeling and Drug Design"
At the Seventh West Coast Protein Crysallogrphy workshop held at Asiloman, CA, 1985, " Real-time Energy Calculations for Docking"
Invited talk at the Molecular Graphics Society Meeting held at Egam, London, 1984, "Real-time energy calculations and Miminization"
Invited talk at the Centre European de Calcul Atomique et Molecularie Workshop on "Nucleotide Binding Proteins" held at Paris, 1982, " Electrostatic potential and conformation of nucleotides"

TEACHING ACTIVITIES:
Delivered a short course on "Molecular Modeling and Visualization" at the Department

of Biochemistry and Molecular Biology, Georgetown University, 1993

Taught a short course on Protein Structure and Modeling for Masters and

Graduate students in the Department of Biochemistry and Molecular Biology,

Georgetown University, 2002

PUBLICATIONS

1. Donghui Kuang, Yi Yao, Minghua Wang, N. Pattabiraman, Lakshmi P. Kotra, and David R. Hampson, (2003) Molecular Similarities in the Ligand Binding Pockets of an Odorant Receptor and the Metabotropic Glutamate Receptors, J. Biol. Chem. 278: 42551 - 42559

2. Nagarajan Pattabiraman (2003) Role of residue packing in protein folding, Trends in Analytical Chemistry, 22:554-560

3. Chenguang Wang, Nagarajan Pattabiraman, Jian Nian Zhou, Maofu Fu,Toshiyuki Sakamaki, Chris Albanese, Zhiping Li, Kongming Wu, James Hulit, Peter Neumeister, Phyllis M. Novikoff , Michael Brownlee, Philipp Scherer, Joan G. Jones, Kathleen D. Whitney, Lawrence A. Donehower, Emily L. Harris, Thomas Rohan, David C. Johns, and Richard G. Pestell (2003) Cyclin D1 repression of Peroxisome Proliferator-activated Receptor g (PPARg) expression and transactivation Molecular Cell Biology. Mol Cell Biol. 23:6159-73.

4. Yao, Yi, Pattabiraman, N. Michne, W., Huang, X., and Hampson, D. R. (2003) Molecular Modeling and Mutagenesis of the Ligand Binding Pocket of the mGluR3 Subtype of Metabotropic Glutamate Receptor. J Neurochem. 86:947-57.

5. Pattabiraman, N*., Martinez, H. and Shapiro, B. Molecular Modeling and Dynamics Studies of HIV-1 Kissing Loop Structures, J. Biomol. Struct. & 2002 20:397-412, 2002.

6. Pattabiraman, N*., Analysis of Ligand-Macromolecule Contacts: Computational Methods. Current Medicinal Chemistry, Mar;9(5):609-21, 2002.

7. Garavelli, J.S., Hou, Z., Pattabiraman, N., Stephens, R. M. The RESID Database of protein structure modifications and the NRL-3D Sequence-Structure Database. Nucleic Acids Res. 29:199-201, 2001.

8. Pattabiraman, N*., Matthews, J. H., Ward, K. B., Mantile-Selvaggi, G., Miele, L. and Mukherjee, A. B. Crystal Structure Analysis of Recombinant Human Uteroglobin and Molecular Modeling of Ligand Binding. Annals of New York Academy of Sciences, 923:348-354, 2000.

9. Gussio, R., Zaharevitz, D. W., McGrath, C., Pattabiraman, N., Kellogg, G. E.,Schultz, C., Linke, A., Kunick, C., Leost, M., Meijer, L. and Sausville, E. A. Structure-bases design modifications of the paullone molecular scaffold for cyclin-dependent kinase inhibition. Anti-Cancer Drug Design, 15:53-66, 2000.

10. Klug, J., Beier, H. M., Bernard, A., Chilton, B. S., Fleming, T. P., Lehrer, R. I., Miele, L., Pattabiraman, N., Singh, G., Uteroglobin/Clara Cell 10-kDaFamily of Proteins: Nomenclature Committee Report. Annals. Of the New York Academy of Sciences, 923:348-354, 2000.

11. Zaharevitz, D. W., Gussio, R., Wiegand, A., Jalluri, R., Pattabiraman, N., Kellogg, G. E., Pallansch, L. A., Yang, S.S. and Buckheit, Jr. B. Discovery of novel HIV-1 reverse transcriptase inhibitors using a combination of 3D database searching and 3D QSAR. Med. Chem. Res. 9:551-564, 1999.

12. Balschi, J.A., Renugopalakrishan, V., Collette, T. W., Dobbs, J. C., Carreira, L. A., Pattabiraman, N., Langridge, R., Sorensen, K. R., Huang, S. G., Macelroy, R. D. , Molecular-Conformations of Dermorphin-A Unique Nonnervous Tissue Mu-Agonist, Neuroscience Research Communications, 25:13-24, 1999.

13. Pattabiraman, N., Occluded Molecular Surface Analysis of Ligand-Macromolecule Contacts: Application to HIV-1 Protease-Inhibitor Complexes. J. Med. Chem. 42:3821-3834, 1999.

14. Mukherjee, A.B., Kundu, G. C., Mantile-Selvaggi, G., Yuan, C.J., Mandal, A.K., Chattopadhyay, S., Zheng, F., Pattabiraman, N., Zhang, Z. Uteroglobin: a novel cytokine? Cell. Mol. Life. Sci., 55:771-787, 1999.

15. Mukherjee, A. B., Kundu, G. C., Pattabiraman, N., Yuan, C-J., Zhang, Z. Uteroglobin (UG): Its physiological role in normal glomerular function uncovered by UG gene knockout in mice. American J. Kidney Diseases, 32:1106-1120, 1998.

16. Gussio, R., Pattabiraman, N., Kellogg, G. E., Zaherevitz, D. W., Utilization of a 3D QSAR methodology for data mining the National Cancer Institute's repository of small molecules in application to HIV-1 reverse transcriptase inhibition. METHODS, 14:255-263, 1998.

17. Pramodh, V., Pattabiraman, N., Le, S-Y., Maizel, Jr., J. V., A molecular modeling study of antibiotics-RNA interaction: application to HIV-1 Rev response element. J. Molecular Structure, 423:125-136, 1998.

18. Le, S. Y., Chen, J. H., Pattabiraman, N., Maizel, J. V. Jr., Ion-RNA interactions in the RNA pseudoknot of a ribosomal frameshifting site: molecular modeling studies. J Biomol. Struct. Dyn. 16:1-11, 1998.

19. Yang, S., Pattabiraman, N., Gussio, R., Pallansch, L., Buckheit, R. W., Bader, J. P. Cross resistance analysis and molecular modeling of nonnucleoside reverse transcriptase inhibitors targeting drug-resistance mutation in the reverse transcriptase of human immunodeficiency Virus. Leukemia, 11:89-92 1997.

20. Gussio, R., Pattabiraman, N., Zaherevitz, D. W., Kellogg, G. E., Topol, I. A., Rice, W. G., Schaeffer, C. A., Erickson, J. W., Burt, S. K. All-atom models for the non-nucleoside binding site of HIV-1 reverse transcriptase complexed with inhibitors: A 3D QSAR approach. J. Med. Chem. 39:1645-1650, 1996.

21. Pattabiraman, N., Ward, K. B., Fleming, P. Occluded Molecular surface: Analysis of protein packing. J. Mol. Recognition. 8:334-344, 1995.

22. Matthews, J. H., Pattabiraman, N., Ward, K. B., Mantile, G., Miele, L. Mukherjee, A. B. Crystallization and Characterization of the recombinant human Clara Cell 10 kDa protein. PROTEINS: Structure, Function and Genetics 20:191-196, 1994.

23. Mukherjee, A. B., Miele, L. M., Pattabiraman, N. Phospholipase A2 Enzymes: Regulation and Physiological Role. Biochemical Pharmacology, 48:1-10, 1994.

24. Le, S.-Y., Pattabiraman, N., Maizel, Jr. J. V., RNA tertiary structure of the HIV RRE domain II containing non Watson-Crick base pairs GG and GA: Molecular modeling studies. Nucleic Acids Research, 22:3966-3976, 1994.

25. Zhou, N., Germann, M. W., van de Sande, J. H., Pattabiraman, N., Vogel, H. J. Solution structure of the parallel-stranded hairpin d(T8<>C4A8) as determined by two-dimensional NMR, Biochemistry, 32:646-656, 1993.

26. Srinivasan, R., Murphy, J. C., Pattabiraman, N. STM observations of two-dimensional condensed layers on solid electrode, Ultramicroscopy, 42-44:453, 1992.

27. Kusunoki, M., George, D. G., Namboodiri, K., Pattabiraman, N. PRENRL_3D; A computer program for an automatic creation of NRL_3D, protein sequence-structure databases, from the Protein Data Bank. Protein Sequence and Data Analysis 4:333-336, 1991.

28. Pattabiraman, N., Ward, K. B. Crepe-ribbon representation for protein structures: comparison of phospholiase A2. J. Mol. Graphics. 9:3-10, 1991.

29. Srinivasan, R., Murphy, J. C., Fainchtein, R., Pattabiraman, N. Electrochemical STM of Condensed Guanine on Graphite, J. Electroanal. Chem., 312: 293-300, 1991.

30. Pattabiraman, N., Namboodiri, K., Lowrey, A., Gaber, B. P. NRL_3D:A Sequence-structure database derived from the Protein Data Bank (PDB) and searchable within the PIR environment. Protein Sequence & Data Analysis 3: 387-405, 1991.

31. Feuerstein, B. G., Pattabiraman, N., Marton, L. J. Molecular mechanics of the interaction of spermine with DNA. Nuc. Acids Res., 18:1271-1282, 1990.

32. Pattabiraman, N., Langridge, R., Laplanche, L. A. Allowed Conformations for protonated and unprotonated lidocaine: Three dimensional isopotential energy surface. J. Chem. Soc. Perkins Trans II:1-5, 1989.

33. Renugopalakrishnan, V., Pattabiraman, N., Prabhakaran, M., Strawich, E., Glimcher, M. J. Tooth enamel protein, amelogenin, has a probable beta-spiral internal channel, Gln112-Leu138, within a single polypeptide chain: Preliminary molecular mechanics and dynamics studies. Biopolymers, 28:297-303, 1989.

34. Feuerstein, B. G., Pattabiraman, N., Marton, L. J., Molecular dynamics of spermine-DNA interactions: Sequence specificity and DNA bending for a simple ligand. Nuc. Acids Res. 17:6883, 1989.

35. Bhatnagar, R., Pattabiraman, N., Sorensen, K. R., Langridge, R., MacElroy, R. D., Renugopalakrishnan, V. Inter-chain proline: proline contacts contribute to the stability of the triple helical conformation. J. Biomol. Struct. and Dynamics. 6:223-233, 1988.

36. Bansal, M., Pattabiraman, N., Molecular mechanics studies on poly(purine).poly(pyrimidine) sequences in DNA: Polymorphism and local variability. Biopolymers 28:531-548, 1988.

37. Devarajan, S., Pattabiraman, N., Shafer, R. H. Effect of discrete distribution of ions on B and Z DNA--A theoretical investigation. Bioploymers, 27:187-200, 1988.

38. Zhou, N., Maria, A., Pattabiraman, N., James, T. L. Molecular modeling of CGTATACG: investigation of the tunnel for TATA region. Biochemistry, 26:7905-7913, 1987.

39. James M. Clark, N. Pattabiraman, Wiley Jarvis and G. Peter Beardsley. Modeling and molecular mechanical studies of the cis-thymine glycol radiation damage lesion In DNA. Biochemistry, 26:5404-5409, 1987.

40. Pattabiraman, N., Rao, S. N., Scott, K., Langridge, R., Kollman, P. A. Molecular mechanical studies on right- and left-handed B-DNA. Biopolymers, 26:403-414, 1987.

41. Suzuki, E.-I., Pattabiraman, N., Zon, G., James, T. L. Solution Structure of d(ATATATATAT) .d(ATATATATAT) via complete relaxation matrix analysis of 2D NOE spectra and molecular mechanics calculations. Biochemistry, 25:6854-6865, 1986.

42. Feuerstein, B. G., Pattabiraman, N., Marton, L. J. Spermine-DNA interactions: a theoretical study. Proc. Natl. Acad. Sci., USA, 83:5948-5952, 1986.

43. Feuerstein, B. G., Pattabiraman, N., Marton, L. J. Theoretical models of spermine/DNA interactions. Annals of the New York Academy of Sciences 483:251, 1986.

44. Pattabiraman, N. Sorensen, K. R., Langridge, R., Bhatnagar, R. S., Renugopalakrishnan, V., Rapaka, R. S. Molecular Mechanics Studies of Dermorphin. Biochem. Biophys. Res. Com. 140:342-349, 1986.

45. Singh, U. C., Pattabiraman, N., Langridge, R., Kollman, P. A. Molecular mechanical studies of d(CGTACG) and its complex with triostin A with the middle AT base pairs in either Hoogsteen and/or Watson-Crick Pairing. Proc. Natl. Acad. Sci., USA, 83:6402-6406, 1986.

46. Haasnoot, C. A. G., Hilbers, C. W., Van der Marel, G. A., Van Boom, J. H., Singh, U. C., Pattabiraman, N., Kollman, P. A. On loop folding in nucleic acid hairpin-type structures. J. Biomol. Struct. Dyn., 3:843, 1986.

47. Pattabiraman, N. Can the double helix be parallel? Biopolymers, 25:1603-1606, 1986.

48. Pattabiraman, N., Levitt, M., Ferrin, T. E., Langridge, R. Molecular modeling and drug design: Real-time energy calculation and minimization. J. Comp. Chem., 6:432-436, 1985.

49. Pattabiraman, N., Langridge, R. Flexibility of 3',5' deoxyribonucleoside diphosphates. J. Biomole. Struct. and Dyn., 2:683-691, 1985.

50. Anathanarayanan, V. S., Brahmachari, S. K., Pattabiraman, N. Proline-containing beta turns in peptides and proteins: Analysis of structural data on globular proteins. Arch. Biochem. Biophys., 232:482, 1984.

51. Pattabiraman, N., Langridge R., Kollman, P. A. An iterative approach to placing counterions around DNA. J. Biomole. Struc. and Dynamics, 1:1525-1533, 1984.

52. Bash, P. A., Pattabiraman, N., Huang, C., Ferrin T. E., Langridge, R. van der Waals surfaces in molecular modeling: An implementation using real-time computer graphics. Science, 222:1325-1327, 1983.

53. Minaga, T., McLick, J., Pattabiraman, N. Kun, E. Steric inhibition of phenyl-boronate complex formation of 2'(5-phosphoribosyl) 5'-AMP, J. Biol. Chem., 257:11942-11945, 1982.

54. Pattabiraman N., Rao, M. J., Flexibility of furanose ring in nucleic acids : A compilation of crystal data. Int. J. Biol. Macromol. Structure, 4:91-95, 1982.

55. Sasisekharan V., Pattabiraman, N. Description of ring puckering of furanose: An analytical approach. Pramana, 15:399-405, 1980.

56. Pattabiraman, N., Rao, S. N. Sasisekharan, V. Is 3'-nucleotide rigid? Nature, 284:187-189, 1980.

57. Sasisekharan, V., Pattabiraman, N. Structure of DNA predicted from the stereochemistry of nucleotide derivatives. Nature, 275:159-162, 1978.

58. Sasisekharan, V., Pattabiraman, N. and Gupta, G. Some implication of an alternative structure for DNA, Proc. Natl. Acad. Science. USA, 75:4092-4096, 1978.

59. Sasisekharan, V., Pattabiraman, N. and Gupta, G. An alternative structure of DNA and its relevance to DNA supercoiling, Current Science, 46:763-764, 1977.

60. Jagadeeswaran, P., Cherayil, J. D., Pattabiraman, N., Sasisekharan, V. A computer method for predicting the sequence of tRNA from its enzymatic digestion products based on the secondary structure of tRNA. Current Science, 46:691-694, 1977.

61. Sasisekharan, V., Pattabiraman, N. Double stranded Polynucleotides: Two typical alternative conformations for nucleic acids. Current Science, 45:779-783, 1976.

BOOK/PROCEEDING CHAPTERS:
1. Pattabirman, N., Computational Methods in the Analysis of Ligand-Macromolecule Contacts

In the Proceedings of the Atlantic Symposium on Computational Biology and Genome Information Systems and Technology (2001), 197-199.

2. Pattabiraman, N., Namboodiri, K. Efforts to improve the utilization of protein sequence and structure databases in the Proceeding of Medications Development, Drug Discovery, Database and Computer-aided Drug Design, NIDA Research Monograph Series 134:114-128, 1993.

3. Pattabiraman, N., Ward, K. B. A novel crepe ribbon representations for protein structures, in Proteins: Structure, Dynamics and Design (Eds. Renugopalakrishnan, V., Corey, P. R., Huang, S. G., Storer, A. Smith, I. C. P.) pp 325-329, 1991.

4. Ward, K. B., Pattabiraman, N. Comparative anatomy of phospholipase A2 structures, in Biochemistry, Molecular Biology and Physiology of Phospholipase A2 and its regulatory factors (Ed. Mukherjee, A. B.) Plenum publishing corporation, New York, pp 23-36, 1990.

5. Gaber, B. P., Nagamo, M., Light, W. R., Chandrasekhar, I., Pattabiraman, N. Molecular modeling of the phospholipid bilayer. in Biotechnological applications of lipid microstructures (Eds. Gaber, B. P., Schnur, J. M., Chapman, D.) Plenum Publishing Corp. New York 1-11, 1988.

6. James, T. L., Borgion, A. M., Bianucci, A. M., Jamin, N. and Pattabiraman, N. Molecular structure determination via complete relaxation matrix analysis of 2D-NOE spectra and molecular mechanics in NMR Spectroscopy in drug research Alfred Benzon Symposium, 26:358-379, 1988.

7. Renugopalakrishnan, V., Pattabiraman, N., Langridge, R., Strawich, E., Glimcher, M. J. Unique secondary structure of amelogenin and its possible implications for the mineralization of enamel in Recent progress in Chemistry and Biology of Centrally Acting peptides (Eds. Dhawan, B. N., Rapaka, R. S.) Central Drug Research Institute, Lucknow, India pp 87-107, 1988.

8. James, T. L., Suzuki, E.-I., Pattabiraman, N., Zon, G. Detailed structure determination of DNA fragments using complete relaxation-matrix analysis of two-dimensional NMR spectra, molecular mechanics calculations and computer graphics in Phosphorus Chemistry Directed Towards Biology. (Edited by K. S. Bruzik and W. J. Stec*, Elsevier Science, Amsterdam, pp 503, 1986.

9. James, T. L, Suzuki, E.-I., Pattabiraman, N., Zon, G. 2D-NOE full relaxzation matrix analysis and molecular mechanics calculations for structure determination in solution: DNA fragments. Ninth ISMAR Proceedings: Bulletin of Magnetic Resonance (Ed. D. G. Gorentstein) 8:152-157, 1986.

10. Bhatnagar, R. S., Pattabiraman, N., Sorensen, K. R., Collette, T. W., Carreira, L. A., Renugopalakrishnan, V., Rapaka, R. Conformational studies of dermorphin from FT-IR, laser Raman, CD, conformational energy calculations and molecular modeling in PEPTIDES: Structure and Function: Proceeding of the Ninth American Peptide Symposium (Eds. Deber, C. M., Hruby, V. J., Kopple, K. D.) pp 525-528, 1985.

11. Pattabiraman, N. Langridge, R. Flexibility of 3',5' riboguanosine diphosphates in Centre European de Calcul Atomique et Moleculaire Workshop Report on Nucleotide Binding Proteins held at Paris, 1982.

12. Pattabiraman, N., Conformation of polynucleotides: an alternative structure for DNA, published in The Lectures of Young Scientists Award for the Year by the Indian National Science Academy (INSA), New Delhi 1980.

ABSTRACTS (Recent)
1. Yao, Y., Pattabiraman, N., Huang, X. P. and Hampson D. R., Molecular Pharmacology of the ligand binding pocket of mGluR3, Fourth International meeting on Metabotropic Glutamate Receptors, Taormina, Italy, September 15-20, 2002.

2. Zaherevitz, D. W., Gussio, R., Pattabiraman, N., Kellogg, G. E., Yang, S., Bader. J. P. Combination of 3D QSAR and 3D database searching in the discovery of novel inhibitors of HIV-1 reverse t transcriptase.Abstract presented at the American Chemical Society meeting held at New Orleans, March 1996.

3. Gussio, R., Pattabiraman, N., Zaharevitz, D. W., Kellogg, G. E., Burt. S. K., Erickson, J. W. Modeling and Classification of Chemically unrelated HIV-1 non-nucleoside reverse transcriptase inhibitors. MEDI 107 Abstrast presented at the American Chemical Society meeting held at Aneheim, California, 1995.

4. Baldwin, E. T., Bhat, T. N., Liu, B., Pattabiraman, N., Erickson, J. W. Structural basis of drug resistance for the V82A mutant of HIV-1 proteinase. Nature Structural Biology 2:244-249, 1995.

5. Pattabiraman, N., Gussio, R., Buckhite, R. W., Zaherevitz, D. W., Erickson, J. W. Molecular modeling studies of a novel class of reverse transcriptase (RT) inhibitor: Calanolide. MEDI 106 Abstrast presented at the American Chemical Society meeting held at Aneheim, California, 1995.

6. Pattabiraman, N., Gussio, R., Topol. I., Burt. S. K., Erickson, J. W. An electronic characterization of a congeneric series of nevirapine analogs. MEDI 33 Abstract presented at the American Chemical Society meeting held at Washington D. C. 1994.

7. Gussio, R., Pattabiraman, N., Kellogg, G., Bhat, T. N., Collins, J., Burt, S. K., Erickson, J. W. HIV-1 Reverse transcriptase nevirapine binding site model: A 3D structural QSAR for ligand design. MEDI 34 Abstract presented at the American Chemical Society meeting held at Washington D. C. 1994.
Nagarajan Pattabiraman Ph. D. Page 1 of 1

Updated 2/18/2004