Electronic Posters: Cardiovascular

Wednesday 13:30-15:30 Computer 36

13:30 3688. 3D Flow-Insensitive Vessel Wall Imaging Using T2PREP PSIR with SSFP

Jingsi Xie¹, Xiaoming Bi², Zhaoyang Fan¹, Himanshu Bhat¹, Saurabh Shah², Sven Zuehlsdorff², Debiao Li<sup>1

1</sup>Departments of Radiology and Biomedical Engineering, Northwestern University, Chicago, IL, United States; ²Siemens Healthcare, Chicago, IL, United States

This work develops a 3D flow-insensitive technique for peripheral vessel wall imaging.

14:00 3689. The Value of Carotid Plaque MRI in the Selection of Choosing Stent-Treatment for Carotid Atherosclerosis Patients

Yan Song¹, Cheng Zhou, Min Chen, Nan Luo, Jiachun Liu, Lijun Wang, Yuan Fu, Xiangyang Ma², Chun Yuan<sup>3

1</sup>Department of Radiology, Beijing Hospital, Beijing, China; ²Philips Global Clinical Research Board, Greater China Region; ³Department of radiology, University Washington, Seattle, United States

The purpose was to evaluate the efficiency of carotid plaque MRI in stent-treatment decision for patients with carotid atherosclerosis comparing with DSA. A total of 17 symptomatic and 37 asymptomatic carotid arteries were evaluated by MRI and DSA. Images were evaluated for luminal stenosis and fibrous cap (FC) rupture, and the stent treatment decision was based on these criterions. Intraplaque hemorrhage and calcification were also evaluated by MRI. The result was that MRI was superior to DSA in determining stent treatment, especially for asymptomatic patients with carotid artery narrowing of less than 70% for its ability to detect FC rupture.

14:30 3690. Comparison of Direct Thrombus Imaging to Multi-Contrast MRI for Assessment of Carotid Atheroma

Victoria Eleanor Louise Young¹, Umar Sadat¹, Andrew J. Patterson¹, Martin J. Graves^1,2, Tjun Y. Tang¹, Peter J. Kirkpatrick³, Jonathan H. Gillard<sup>1

1</sup>University Department of Radiology, Addenbrookes Hospital, Cambridge, Cambridgeshire, United Kingdom; ²Department of Medical Physics, Addenbrookes Hospital, Cambridge, Cambridgeshire, United Kingdom; ³Department of Neurosurgery, Addenbrookes Hospital, Cambridge, Cambridgeshire, United Kingdom

Multi-contrast MRI is used for detection of complex carotid plaque, however, it is time consuming. Direct thrombus imaging (DTI) has been used previously to detect intraplaque haemorrhage. The aim of this study was to assess whether DTI could be used independent of other sequences to demonstrate complex disease. 55 patients with carotid stenosis (>30%) were imaged at 1.5T using a 4 channel phased-array carotid coil. Independent observers reviewed the multi-contrast imaging and DTI separately. DTI was found to be highly sensitive/specific for detecting complex plaque. DTI can be used independent of other imaging to identify complex plaque.

15:00 3691. Large Field-Of-View Submillimeter Isotropic Resolution Bilateral Peripheral Vessel Wall MRI Using 3D Fast Spin Echo with Flow-Insensitive Blood Suppression at 3 Tesla

Thanh D. Nguyen¹, Keigo Kawaji², Pascal Spincemaille¹, Martin R. Prince¹, Yi Wang<sup>1,2

1</sup>Radiology, Weill Cornell Medical College, New York, NY, United States; ²Biomedical Engineering, Cornell University, Ithaca, NY, United States

Black blood (BB) MRI can be used to characterize vessel wall and quantify atheresclerotic plaque burden in patients with peripheral vascular disease. T2prep inversion recovery (T2IR) has been shown to provide flow-insensitive BB contrast for 2D peripheral vessel wall MRI at 1.5T at the cost of reduced wall SNR The aim of this study is to achieve a considerable increase in T2IR BB imaging efficiency to obtain large field-of-view bilateral peripheral coverage with sub-millimeter isotropic resolution in reasonable scan time using SNR-efficient volumetric 3D fast spin echo acquisition at 3T. The developed sequence was capable of providing large volumetric coverage, excellent arterial and venous blood suppression and fat suppression, as well as good vessel wall visualization in healthy volunteers.