Israel state records י"ג בשבט התשס"ח January 20, 2008

150197
[21][11]
שיטת דחיסה ושחזור של מידע מודמה			METHOD OF COMPRESSING AND RESTORING IMAGE DATA			[54]
	20.12.2000					[22]
	JP	[33]	20.12.1999	[32]	H11-360326	[31]
	JP		05.04.2000		103889/2000
	JP		18.12.2000		383573/2000
Int. Cl.8 H04N 001/41, 001/413						[51]
			VENTURE WAVE INC., JAPAN SHOUICHI KOJIMA, JAPAN			[71]
	WO/2001/047243					[87]
ד"ר מרק פרידמן בע"מ, מגדל משה אביב, ק.54 , רח ז'בוטינסקי 7, רמת- גן			DR. MARK FRIEDMAN LTD., MOSHE AVIV TOWER, 54TH FLOOR, 7 JABOTINSKY ST., RAMAT GAN 52520			[74]

[57] An image data compressing method comprising the steps of: extracting image elements included in a digital image obtained from a paper surface; performing data compression on each of the image elements extracted by compressing methods corresponding to the image elements; and storing each of the image element data in compressed form in a memory, wherein when the image elements extracted include a dot image element composed of dots, the image element data in compressed form associated with the dot image element is generated so that the image element data in compressed form comprises: position information corresponding to positions of the dot, and screen ruling information corresponding to an arrangement of the dots.

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150235			[21][11]
נגזרות של N–בנזיל–אינדול–3–איל חומצה גליאוקסלית מותמרת בעלות השפעה נוגדת גידולים, מלחיהן מהוספת חומצות, תכשירי רוקחות המכילים אותן והשימוש בהן			SUBSTITUTED N-BENZYL-INDOL-3-YL GLYOXYLIC ACID DERIVATIVES HAVING AN ANTI-TUMORAL EFFECT, ACID ADDITION SALTS THEREOF, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USE			[54]
	19.12.2000					[22]
	DE	[33]	23.12.1999	[32]	19962300.7	[31]
Int. Cl.8 A61K 031/395, A61P 035/00, C07D 209/22, 401/12, 401/14, 403/10						[51]
			ZENTARIS GMBH, GERMANY			[71]
	WO/2001/047913					[87]
ריינהולד כהן ושותפיו, רחוב אחד העם 21 , ת.ד. 4060, תל אביב			REINHOLD COHN AND PARTNERS, 21 AHAD HA'AM ST., P.O.B. 4060, TEL AVIV 61040			[74]

[57] Substituted N-benzylindol-3-ylglyoxylic acid derivatives having antitumour action of the formula

where the radicals R, R₁, R₃ and R₄ are as defined in the specification;

R₂ is a phenyl ring, which is mono- or polysubstituted by (C₁-C₆)-alkyl, (C₁-C₆)-alkoxy, cyano, halogen, trifluromethyl, hydroxyl, benzyloxy, nitro, amino, (C₁-C₆)-alkylamino, (C₁-C₆)-alkoxycarbonylamino and by the carboxyl group or by the carboxyl group esterified with C₁-C₆-alkanols, or a pyridine of the formula

and its N-oxide, where the pyridine is selectively attached at the ring carbon atoms 2, 3 and 4 and can be substituted by the substituents R₅ and R₆, R₅ and R₆ in formula 2 can be identical or different and have the meaning (C₁-C₆)-alkyl and the meaning (C₃-C₇)-cycloalkyl, (C₁-C₆)-alkoxy, nitro, amino, hydroxyl, halogen and trifluromethyl and further are the ethoxycarbonylamino radical and the group carboxylalkyloxy in which the alkyl group can have 1-4 C atoms, or R₂ is a 2- or 4-pyrimidinyl heterocycle, where the 2-pyrimidinyl ring can be mono-or polysubstituted by the methyl group, furthermore can be the 2-, 3-, 4-, 5-, 6-, 7- and 8-quinolyl structure substituted by (C₁-C₆)-alkyl, halogen, the nitro group, the amino group and the (C₁-C₆)-alkylamino radical, can be a 2-, 3- or 4-quinolylmethyl group, where the ring carbons of the pyridylmethyl radical of the quinolyl group and of the quinolymethyl radical can be substituted by (C₁-C₆)-alkyl, (C₁-C₆)-alkoxy, nitro, amino and (C₁-C₆)-alkoxycarbonylamino, or R₂ in the case in which R₁=hydrogen, methyl or benzyl group and the benzyloxycarbonyl radical the tert-butoxycarbonyl radical (BOC radical) and the acetyl group can furthermore be the following radicals:

-CH₂COOH; -CH(CH₃)-COOH; (CH₃)₂CH-(CH₂)₂CH(COOH)-;

H₃C-H₂C-CH(CH₃)-CH(COOH)-; [HO-H₂C-CH(COOH)-;

phenyl-CH₂-CH(COOH)-; (4-imidazolyl)-CH₂-CH(COOH)-;

NH=C(NH₂)-NH-(CH₂)₃-CH(COOH)-; H₂N-(CH₂)₄-CH(COOH)-;

H₂N-CO-CH₂-CH(COOH)-; HOOC-(CH₂)₂-CH(COOH)-; or

R₂ in the case in which R₁ is hydrogen, the Z group, the BOC radical, the acetyl or the benzyl group can furthermore be the acid radical of a natural or unnatural amino acid, e.g. the α-glycyl, the α-sarcosyl, the α-alanyl, the α-leucyl, the α-isoleucyl, the α-seryl, the α-phenylalanyl, the α-histidyl, the α-prolyl, the α-arginyl, the α-lysyl, the α-asparagyl and the α-glutamyl radical, where the amino groups of the respective amino acids can be present unprotected or can be protected; a possible protective group of the amino function is the carbobenzoxy radical (Z radical) and the tert-butoxycarbonyl radical (BOC radical) as well as the acetyl group; in the case of the asparagyl and glutamyl radical of R₂, the second, unbonded carboxyl group is present as a free carboxyl group or in the form of a carboxyl group esterified with C₁-C₆-alkanols, e.g. as a methyl, ethyl or as a tert-butyl ester; furthermore, R₂ can be the allylaminocarbonyl-2-methylprop-1-yl group; and Z is O and S.

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150565			[21][11]