Model gpa objective X working Compendium

2009-2012 Work Plan Number	GPA4.21n Formerly AA6:NM4
GPA Objective	Objective 4: To provide and communicate evidence for action and practice
CC or NGO Name	Health and Safety Laboratory, UK
Project title	Nano-Comms: A Technical Observatory for the dissemination of information regarding nanoparticle health and safety issues
Keywords	Nanoparticles, nanomaterials, nanotechnology
Project leader Email address	Rosemary Gibson [e-mail]
Partners (of the CC Network)	FIOH Institute of Occupational Medicine, UK (Lang Tran [e-mail]) Federal Institute for Occupational Safety & Health (BAuA), Germany (Bruno Orthen [e-mail]) Canadian Centre for Occupational Health & Safety (CCOHS; P. K. Abeytunga [e-mail]) European Institute of Health and Social Welfare (Manuel Peña [e-mail]) Institute for Work and Health, Lausanne, Switzerland (Michael Riediker [e-mail]) National Institute for Occupational Safety and Health (NIOSH), USA, (Charles Geraci; Vladimir Murashov [e-mail]; [e-mail]) Office of the Australian Safety & Compensation Council, Department of Employment and Workplace Relations (Peta Miller; Anh-Thu Stuart [e-mail]; [e-mail])
Other partners	ICOH IOHA
Funding	In place
Objective of the project	This project will help to coordinate the production, management and provision of information regarding the health and safety issues surrounding the development, manufacture and use of nanoparticles in collaboration with national and international partners.
Project outcome(s) and deadline(s) for completion of the project	To develop a network of international experts in the field of health and safety issues of nanoparticles To identify processes that involve manufacture of nanoparticles and may lead to exposure To review exposure modelling processes To Categorise and map Health Risks associated with exposure To assist the development of standards (including the best ways to communicate current evidence base) To engage with regulators, manufacturers, down-stream users and researchers to ensure communications meet the needs of the audience
Target group and/or beneficiaries	Industry, research institutions, trade unions, NGOs
Summary of the project	This project will develop a portal for the collection, production and dissemination of information regarding health and safety issues of nanoparticles
Dissemination	Dissemination will occur through a number of routes including: Information posted on the HSL website Presentations at national/international meetings Provision of a Q&A service
Impact (global or regional)	Global
Progress on project	Significant progress has been made in developing a network of international experts through: Participation in a Coordination Action submitted to EU Framework 7, coordinated by Michael Riediker (AA6: project 16), involving >80 researchers world-wide. Presentations at international conferences. HSL summarises the published literature on engineered nanoparticles in a NanoAlert bulletin (now available on HSE’s website), which has generated very positive global feedback. HSL has launched the Centre for Interdisciplinary Nano-Research (CiNR), with the aims of addressing the potential health and safety risks of nanoparticles and is engaging with nanomaterials trade associations (e.g. NIA, ENTA), and individual businesses.
List of outcomes already achieved by this project	Partner in NanoImpactNet Coordination Action (EU FP7). Workshop on “Strategies to assess occupational health effects of nanomaterials”, held in conjunction with the FP7 project NanoImpactNet, March 2009.
List of additional outcomes expected from this project by 2012	Report on “Strategies to assess occupational health effects of nanomaterials”. Report on risk assessment approaches for handling nanomaterials.
List of critical deliverables needed by 2012 to assist developing countries	Development of strategy for sharing OH knowledge with professionals in 2^nd world & developing countries.

2009-2012 Work Plan Number	GPA4.21o Formerly AA6:NM5
GPA Objective	Objective 4: To provide and communicate evidence for action and practice
CC or NGO Name	Institute of Occupational Medicine, Edinburgh, UK
Project title	Assessing the Hazard of Nanomaterials
Keywords	nanoparticles, nanotubes, in vitro tests, toxicology
Project leader Email address	Dr Lang Tran [e-mail]
Partners (of the CC Network)	Institute for Work and Health, Lausanne, Switzerland, (Michael Riediker [e-mail]) Federal Institute for Occupational Safety & Health (BAuA), Germany (Bruno Orthen [e-mail]) National Institute for Occupational Safety and Health (NIOSH), USA, (Charles Geraci; Vladimir Murashov [e-mail]; [e-mail]) Health and Safety Laboratory, UK (Rosemary Gibson [e-mail]) - University of Edinburgh, UK - Napier, UK - GSF, Germany - NIOH, Denmark - University of Venice, Italy
Other partners
Funding	Funding for 1^st phase already available through FP6 project PARTICLE_RISK
Objective of the project	The project will seek to assess the hazard of nanomaterials generated by new, emerging sciences and technologies. Specifically, the project will seek to determine which nanoparticle attributes are most influential in driving toxicity on different target organs and species; to use results to inform a risk assessment framework for nanoparticles in an occupational setting. To disseminate the results to existing networks on nanomaterials health/safety issues.
Project outcome(s) and deadline(s) for completion of the project	The outcomes should be: Recommendation of in vitro toxicology tests for nanoparticles and nanotubes; Identification of nanoparticle/nanotube attributes which can be used in risk assessment. Dissemination of results at international conferences (2007) and in peer-reviewed journals (2008).
Target group and/or beneficiaries	Professionals in Toxicology; Stakeholders: Governmental and NGO regulatory agencies; new and emergent sciences and technologies industry.
Summary of the project	New and emerging sciences and technologies produce nano-scaled materials which could pose a hazard to the human and environment health. The mechanisms by which these materials cause the adverse effects are not clearly understood. In this project we will be investigating the toxic effects, of a panel of nanoparticles/nanotubes, on the body systems, e.g. pulmonary, central nervous, hepatic and cardio-vascular systems.
Dissemination	international conferences international peer-reviewed journals specially held workshops bringing together stakeholders such as governmental and non-governmental agencies
Impact (global or regional)	Global
PROJECT PROGRESS AT 1 OCTOBER 2007	The following project objectives have been achieved thus far: Implementation of the experimental protocols Recruitment and training of staff in working safely with NESTP Distributing funding to all partners Implementing the WP WP1 facilitated local and project meetings WP2 procured, distributed (to the corresponding partners) and characterised the NESTP WP3 performed in vitro and animal experiments WP4 performed in vitro and animal experiments WP5 constructed exposure assessment models WP6 arranged PARTICLE_RISK results, which were presented at the International Conference on Nanotoxicology, held in Venice (April 2007)
List of outcomes already achieved by this project	As above
List of additional outcomes expected from this project by 2012
List of critical deliverables needed by 2012 to assist developing countries

2009-2012 Work Plan Number	4.21p Previously AA6:NM6
GPA Objective	NanOSH Italy
CC or NGO Name	4.21
Project title	Priority 1: Encourage practical research on emerging issues, including nano-materials and climate change (Action 4.21). Projects include communication with low and medium income countries of interventions to ensure worker health.
Keywords	ISPESL – Dept. of Occupational Medicine ITALY
Project leader Email address	Sergio Iavicoli ([e-mail]) Fabio Boccuni ([e-mail])
Partners (of the CC Network)
Other partners
Funding	Italian Ministry of Health
Objective of the project	Salvatore Maugeri Foundation of Pavia, Italy University of Rome “Tor Vergata”, Italy University of Parma, Italy National Institute of Physics (INFN), Italy
Project outcome(s) and deadline(s) for completion of the project	The limited knowledge on risk assessment and health effects of work-related exposure to nanomaterials (with specific focus on Carbon Nanotubes (CNT) highlights the importance to develop a methodology for work-related risk assessment in order to properly address the subsequent management and communication stages In the first stage, the project will be developed following two parallel lines. 1. Physical-chemical characterization of appropriately produced functionalized CNT and study of interactions with biological systems. 2. Assessment of work-related exposure to CNT and analysis of risk processes. In a second stage the results of the two project lines will be summarized in the development of a general model for risk assessment applicable to the work environments likely to be affected by CNT exposures. Later this model will be validated through an application on the territory.
Target group and/or beneficiaries	Occupational Health and Prevention stakeholders, National Health System, Exposed Workers.
Summary of the project	Meetings of Research Working Groups will be scheduled.
Dissemination	Nanomaterials production (2008) Characterization and functionalization (2009) Toxicological analysis (2009) Exposure assessment and analysis of at risk processes (2009) Qualitative evaluation with control banding methodology (2010) Model of workplace monitoring (2010) Validation of methodology (2010)
Impact (global or regional)	Definition of validated protocols of study. Scientific reports will be published each year.
PROGRESS ON PROJECT 1 OCTOBER	- To identify the production stages potentially at risk for workers and then assess number of workers potentially exposed in Italy (2008) - To strengthen collaboration in Italy through the creation of a Network involving the institutions more active in the sector at national level (2008) - To identify a monitoring system for the number of nanoparticles in the air exhaled by subjects exposed to CNT (2009) - To develop an innovative methodology for risk assessment to be used for prevention purposes in exposed subjects and for a correct risk management for health and environment (2009) - To start knowledge transfer and risk communication with relation to risk perception level by all the involved subjects (2010)
List of outcomes already achieved by this project	Summary of the key issues related to nanotechnology and OSH in terms of scientific knowledge level. In vitro study of genotoxic and oxidative effects induced on human bronchial cells by MWCNT. Identification of industrial sectors involved and potential occupational exposure to engineered nanomaterials in Italy. Risk assessment model of occupational exposure to nanomaterials. Development and set-up of a portable device to monitor airway exhalation and deposition of particulate matter. National Working Group on occupational exposure to nanomaterials.
List of additional outcomes expected from this project by 2012	White Paper on occupational exposure to engineered nanomaterials in Italy (2010). Analysis of OSH programs specific for nanotechnologies in Italian enterprises (2011) Development of a shared frame of knowledge, objectives and actions leading to constructive and practicable regulatory solutions for the responsible and sustainable development of Nanotechnologies at national level (2012)
List of critical deliverables needed by 2012 to assist developing countries	Practical tools for qualitative evaluation with control banding methodologies International cooperation for a sustainable development of nanotechnologies Tools for communication and knowledge transfer taking into account the workers risk perception

2009-2012 Work Plan Number	4.21q New Project
CONTRIBUTING PROJECT Title Work plan project number	Development of database for individuals working with engineered nanomaterials
GPA Objective and Action	GPA Objective 4
Priority Initiative	Priority 1, A
Responsible CC or NGO Name	NUS
Project leader	Judy Sng, [e-mail]
Network partners	NIOSH, U.S.A., Prof Paul Schulte [e-mail] NUS Environmental Research Institute, Singapore, A/Prof Liya Yu [e-mail]
WHO Regions involved in this CONTRIBUTING project
Country ministries involved in this CONTRIBUTING project
External partners for this CONTRIBUTING project
Summary of the project	This project aims to: 1) Establish an exposure registry of workers exposed to nanomaterials from a representative group of companies to gauge the extent of nanomaterial exposure among workers in Singapore. We are targeting our university’s Nanotechnology Initiative researchers as the starting point.   2) Use the registry database as a possible stage to evaluate any possible medical surveillance that would be recommended by WHO, ILO or other international agencies
Target group and/or beneficiaries	Initial : Researchers based in the National University of Singapore and other research institutions who are handling nanomaterials Subsequent: Workers in nanotechnology industries
Events-opportunities for furthering the project	After the university database is established, the knowledge & insights gained from this would be used to reach out to commercial nanotechnology industries in and around Singapore.
Expected results of this project by 2012 (outcomes)	We aim to have a registry of persons working with Nanomaterials, documenting the type and nature of exposure. This will form an important basis for establishing occupational health and safety policies for this rapidly growing emerging industry.
Indicators of achievement (impact)	Appropriate occupational health and safety measures will eventually be worked out and implemented in the nanotechnology industry while it is still in relatively early stages of development in many countries.
Major Milestones (list up to three dates and milestones)	End Oct 2009 – Set up first exposure registry for researchers in NUS June 2010 – Open to researchers in other institutions, namely Agency for Science, Technology and Research (Institute of Materials Research and Engineering), Nanyang Polytechnic and Nanyang Technological University By end 2010 – Role out to major nanotechnology industries in Singapore
Public health impact	Nanotechnology is an emerging industry that is rapidly gaining in importance both in Asia and worldwide. The potential health impact on workers and consumers has yet to be documented, as the number of nanotechnology-enabled consumer products on the market increases every month. Exposure registries are an important starting point to monitor potential hazards, and have been of great usefulness in occupational and environmental exposure situations.
Funding source(s)	Research grant from university
Dissemination
List of outcomes already achieved by this project	1) Online system for NUS researchers to log in details on nanomaterials use in their labs has been developed by the NUS Office of Safety, Health and Environment 2) Potentially high-risk labs in NUS have been identified for screening by end 2009
List of additional outcomes expected from this project by 2012	1) development of a Job Exposure Matrix for occupational groups exposed to engineered nanomaterials 2) development of protocol for health surveillance for persons exposed to engineered nanomaterials
List of critical deliverables needed by 2012 to assist developing countries	health surveillance protocol for persons exposed to engineered nanomaterials

2009-2012 Work Plan Number	4.21v New Project
CONTRIBUTING PROJECT Title Work plan project number	Assessing the Hazard of Nanoparticles and Communicating the Risks: SAFENANO
GPA Objective and Action	4
Priority Initiative	4.1
Responsible CC or NGO Name	Institute of Occupational Medicine (IOM), UK
Project leader	Dr. Rob Aitken [e-mail]
Network partners	-
WHO Regions involved in this CONTRIBUTING project	-
Country ministries involved in this CONTRIBUTING project	Funding is provided by DIUS/Technology Strategy Board in the UK. The Project Officer is Mike Oldham [e-mail]
External partners for this CONTRIBUTING project	Prof Vicki Stone, Edinburgh Napier University is a partner in the project. [e-mail] A range of external partners contribute information to the site on an ad hoc basis including Andrew Maynard, Woodrow Wilson Project on Emerging Nanotechnologies Peter Hatto, Chair of ISO 229: Nanotechnologies Prof Ken Donaldson, Edinburgh University
Summary of the project	SAFENANO is designed to capture and disseminate the emerging evidence on health, safety, toxicology and risks of manufactured nano-particles, using the SAFENANO website: http://www.safenano.org/, weekly bulletins and a community site. The need for accessible and up-to-date health and safety information is growing because emerging evidence is numerous, complex and often difficult to interpret. SAFENANO benefits from IOM’s extensive research collaborations and networks on nanotechnology risks, and our links with wider nano-technology websites such as those hosted by ICON, NANOWORK, OECD etc. SAFENANO also provides services to government and industry (review, measurements, testing) on a commercial basis.
Target group and/or beneficiaries	The target audience is industry, policy leads and others involved in the manufacture and use of nanomaterials. It is however a publicly accessible website with open access.
Events-opportunities for furthering the project	As a website, the primary route of dissemination is through the web. We also send out weekly bulletins to more than 1000 recipients. We are also exploring the use of social network technology such as twitter.com. Many of SAFENANO’s outputs are public domain documents and are made available through SAFENANO, IOM’s and the sponsors’ website. We also present SAFENANO at national and international conferences and workshops (more than 20 times in the last year)
Expected results of this project by 2012 (outcomes)	The SAFENANO ‘result’ is a continuity of accessible provision of up-to-date information; i.e. the result is a maintained and developed website. We will continue to provide this, through 2012 and beyond, as long as there is a need, and funding.
Indicators of achievement (impact)	Number and distribution of ‘hits’; Number and distribution of signed-up members of the SAFENANO community
Major Milestones (list up to three dates and milestones)	Establishment of an active website – achieved Establishment of regular commented bulletin – achieved Improved integration with other web based information services - 2011
Public health impact	Impossible to quantify; but the underlying purpose of SAFENANO is to disseminate accurate information about the risks to health from manufactured nanoparticles and so to help with (i) assessment, control and management of the risks; (ii) inform the public debate about these risks
Funding source(s)	Currently funded by the Technology Strategy Board of the Department of Innovation, Universities and Skills (DIUS) in the UK.
Dissemination	SAFENANO is inherently a dissemination project
List of outcomes already achieved by this project	Establishment of an active website – achieved Establishment of regular commented bulletin – achieved
List of additional outcomes expected from this project by 2012	Improved integration with other web based information services - 2011
List of critical deliverables needed by 2012 to assist developing countries

2009-2012 Work Plan Number	4.21ao
PROJECT Title	Application of practical research to help ensure that the OHS Regulatory Framework and OHS management effectively covers issues associated with nanotechnology.
GPA Objective	Objective 4: “To provide and communicate evidence for action and practice”: (Action 4.21)
Priority Number and Area (if applicable)	Priority 1(a): Encourage practical research on emerging issues, including nano-materials
Responsible CC or NGO Name	Safe Work Australia
Project leader(s)	Dr Howard Morris [e-mail]
Network partners	NA
WHO Regions involved in this project	NA
Country ministries involved in this project	NA
External partners for this project	Safe Work Australia is active in a wide range of Australian & International Forums on this topic, including the ISO Nanotechnology Technical Committee (through the Standards Australia Nanotechnology Committee) and the OECD Working Party on Manufactured Nanomaterials (WPMN) project on Exposure Measurement & Mitigation.
Summary of the project	Safe Work Australia is supporting development of a nationally coordinated approach to promoting workplace safety in the use of nanotechnology There are five focus areas in the Nanotechnology OHS Program: 1. Ensuring the Australian OHS regulatory framework can effectively protect workers from the potential health and safety impacts of nanotechnologies 2. Improving understanding of the hazardous properties of engineered nanomaterials 3. Developing nanoparticle measurement capability 4. Understanding the effectiveness of workplace controls 5. Providing support for nanotechnology organisations Projects include; reviews of toxicology, safety hazards and the effectiveness of workplace controls, examining the feasibility of group based exposure standards and control banding, fieldwork to evaluate workplace exposures and emissions and the effectiveness of workplace controls, examining options for substitution/modification to reduce potential toxicity, examining MSDS & labelling for nanomaterials, an intercomparison of measurement methods for various types of nanomaterials, and an examination of laser printer emissions. Specific projects related to carbon nanotubes include developing capability for detection of CNTs in the workplace, and examination of the durability and biopersistence of CNTs. Specific guidance will be developed targeting key areas such as handling carbon nanotubes, preparing MSDS and undertaking classification of engineered nanomaterials.
Target group and/or beneficiaries	The Nanotechnology OHS Program aims to support regulators, manufacturers, importers, suppliers, and for researchers, employers, and employees in nanotechnology organisations working with engineered nanomaterials. The Program focuses on key issues globally associated with nanotechnology OHS globally, and is aligned with work of the OECD and ISO.
Major Milestones (list up to three dates and milestones)	The development of a nationally coordinated approach to promoting workplace safety in the use of nanotechnology by 2012.
Dissemination plan	Dissemination is through the Safe Work Australia website nanotechnology website and through the extensive networks and forums in which Safe Work Australia participates.
Funding source(s)	The Australian Federal Government through the Department of Innovation, Industry, Science and Research, and Safe Work Australia.
List of outcomes already achieved by this project	Dr Morris and his team have developed links internationally through ISO and the OECD, and bilaterally with NIOSH (US), HSE & HSL (UK), and BAuA (Germany), and through the World Congress on Safety and Health. The project on durability & biopersistence of carbon nanotubes, supported by Safe Work Australia, involves collaborative research between CSIRO in Australia, and Edinburgh University and the Institute of Occupational Medicine in the UK. The team will be seeking to support collaborative research projects wherever possible. In Australia, Safe Work Australia participates number of forums to progress nanotechnology OHS issues: Safe Work Australia’s tripartite Nanotechnology OHS Reference Group (Dr Morris is the Chair of this group) Safe Work Australia’s Nanotechnology OHS Measurement Reference Group Federal Government’s Nanotechnology Interdepartmental Committee and Health, Safety & Environment Working Group Standards Australia’s Nanotechnology Committee and the Health, Safety & Environment sub-committee Australian Institute of Occupational Hygienists Conference (Dr Morris will coordinate a session on Nanoparticle Measurement at the 2009 conference) International Conference on Nanoscience & Nanotechnology Safe Work Australia also works with members of the NanoSafe Australia network, which is a network of academic risk assessors, occupational hygienists and toxicologists. Dr Morris is also a member of the Technical Program Committee for the Aerosol Society’s workshop and scientific conference on workplace aerosols including nanoscale aerosols in Karlsruhe, Germany in June/July 2010.
List of additional outcomes expected from this project by 2012	Development of an OHS regulatory response to the emerging issue of the use of engineered nanomaterials, which encompasses a whole-of-government approach, and is consistent with international systems and approaches. The development of evidence-based guidance material for manufacturers, importers, suppliers, and for researchers, employers, and employees in nanotechnology organisations working with engineered nanomaterials.

2009-2012 Work Plan Number (to be assigned by WHO)	4.21av
PROJECT Title	New knowledge development on nanotechnologies
GPA Objective (e.g. GPA5) and GPA Action (e.g Action 28)	GPA4 – To Provide and communicate evidence for action and practice
Priority Number (e.g. 5.3) and Area (if applicable) e.g Agriculture	Priority 4.1 To encourage practical research on emerging issues, including nano-materials
This project also contributes to other GPA Priorities (List them, if applicable).	Priority 1.2 Develop and disseminate evidence-based tools and raise awareness for the prevention of dust-related diseases (fine coarse dusts)
Responsible CC or NGO Name	Mr. Paul-Émile Boileau, Scientific director
Project leader(s) (contact name and email address)	Mr. Claude Ostiguy, Chemist, Ph.D. in Inorganic Chemistry. Director of Research and Expertise Support Department, IRSST [e-mail]
Network partners (CC name, country, email)	Partner : JNIOSH, Japan Anticipated partners : NIOSH, USA; HSL, UK;
WHO Regions involved in this project (contact name and email)	Region of the Americas
Country ministries involved in this project (contact name and email)
External partners for this project (contact name, organization and email)	Toan Vu-Khanh, École de technologie supérieure (Montreal, Canada) [e-mail] - Project 1 Fariborz Haghighat / Université Concordia [e-mail] - Project 2 Victor Songmene, École de technologie Supérieure (Montreal, Canada) [e-mail] - Project 3 André Dufresne, Université de Montréal (Canada) [e-mail] - Project 4 Charles-Anica Endo Nano-Québec [e-mail]
Summary of the project (max 100 words)	In the context of a partnership with NanoQuébec, the IRSST’s research program focuses specifically on the following avenues : Evaluation of the effectiveness of means of control aimed at ensuring protection against the health effects related to exposure to different types of nanoparticles. Project 1 Development of a method for measuring nanoparticle penetration through glove materials under conditions simulating workplace use Project 2 Development of a procedure for measuring the effectiveness of filters for collecting nanoparticles Characterization of nanoparticles and, in particular, the exposure of individuals to different types of nanoparticles (respiratory, cutaneous routes, etc.). Project 3 Procedure for measuring and controlling manufactured nanoparticles Project 4 Characterization and control of occupational exposure to nanoparticles
Target group and/or beneficiaries	Quebec employers, workers and researchers using, manufacturing or synthesizing nanoparticles. All workplaces and research centres around the world using, manufacturing or synthesizing nanoparticles.
Major Milestones (list up to three dates and milestones)	Estimated deadline of deliverables for all projects : January 2011
Dissemination plan	Government of Canada - House of Commons Standing Committee on Health (June 2010) IRSST scientific reports (2011 – 2012) International scientific conferences PAHO/WHO documents
Funding source(s)	IRSST (Montréal, Canada) Nano-Québec (Montréal, Canada)
List of outcomes already achieved by this project (in this area of interest)	Production of state-of-the-art reviews on health effects, risks, and OHS prevention measures, as well as a good practices guide on the safe handling of nanoparticles. Health Effects of Nanoparticles - Second Edition, IRSST, 2008   Best Practices Guide to Synthetic Nanoparticle Risk Management, IRSST, 2009 Nanoparticles - Current Knowledge about Occupational Health and Safety Risks and Prevention Measures – Second Edition, forthcoming Summer 2010
List of additional outcomes expected from this project by 2012
List of additional outcomes expected by 2016	There is a probability to produce state-of-the-art review updates on health effects, risks, and OHS prevention measures, as well as a good practices guide on the safe handling of nanoparticles.

Work plan project number (to be added by WHO)	4.21as
Please indicate whether this is a:	New Project
CONTRIBUTING PROJECT Title	Participation in ISO TC 229/WG 3 /PG 8 "Guidelines for occupational risk management applied to engineered nanomaterials based on a control banding approach"
GPA Objective and Action	Objective 4: To provide and communicate evidence for action and practice. Objective 2: To promote and protect health at the workplace.
Priority Initiative	Priority GPA4.1 and GPA Priority 2.1
Responsible CC or NGO Name	IOHA
Project leader (contact name and email address)	Dave Zalk (IOHA envoy) [e-mail] Henri Heussen (IOHA envoy) [e-mail]
Network partners (CC name, country, email)
WHO Regions involved in this CONTRIBUTING project (contact name and email)
Country ministries involved in this CONTRIBUTING project (contact name and email)	Dutch Ministry of Social Affairs and Employment
External partners for this CONTRIBUTING project (contact name, organization and email)	Dutch Ministry of Social Affairs and Employment Arbo Unie
Summary of the project (max 100 words)	Within the ISO Technical Committee 229 the standardisation of nanotechnoloyg in all its aspects takes place. In Working Group 3 HSE aspects are dealt with. Within this WG Control Banding is specifically adressed in Project Group 8. Several experts nominated by their national Standardisation Institutes are working on a technical guidance to provide approaches for control banding on manufactured nano objects. Participation will ensure high quality standard technical guidance for developing a control banding approach targeted at manufactured Nano objects.
Target group and/or beneficiaries	SMEs
Events-opportunities for furthering the project
Expected results of this project by 2012 (outcomes)	Standard technical guidance for developing control banding approach targeted at Manufactured Nano Objects
Indicators of achievement (impact)
Major Milestones (list up to three dates and milestones)
Public health impact
Funding source(s)
Dissemination	ISO standard, IOHA, WHO CC Network

Work plan project number	4.21at
Please indicate whether this is a:	New Project
CONTRIBUTING PROJECT Title	Stoffenmanager Nano, version 1.0
GPA Objective and Action	Objective 4: To provide and communicate evidence for action and practice. Objective 2: To promote and protect health at the workplace.
Priority Initiative	GPA 4.1 GPA 2.1
Responsible CC or NGO Name	TNO Quality of Life, Gerard Zwetsloot
Project leader (contact name and email address)	Maikel van Niftrik ([e-mail])
Network partners (CC name, country, email)	TNO Quality of Life in Hoofddorp, the Netherlands Albert Hollander, TNO Quality of Life, [e-mail] IOHA
WHO Regions involved in this CONTRIBUTING project (contact name and email)
Country ministries involved in this CONTRIBUTING project (contact name and email)	Dutch Ministry of Social Affairs and Employment Henri Geron, Dutch Ministry of Social Affairs and Employability, [e-mail]
External partners for this CONTRIBUTING project (contact name, organization and email)	Michel van Wijk, BECO, [e-mail] Jan Boonstra, Dutch Labor Inspectorate, [e-mail] Henri Heussen. Arbo Unie, ([e-mail])
Summary of the project (max 100 words)	The potential hazard of and health risks after exposure to man-made nano objects are mostly unknown. Therefore the Dutch government decided in 2009 to only allow the industrial and professional use of nano objects if companies adhere to the precautionary principle. To reduce the amount of uncertainty related to working with manufactured nano object a risk banding tool is being developed: Stoffenmanager Nano. The first version of Stoffenmanager Nano will feature a hazard classification scheme, a qualitative inhalation exposure model and a risk matrix. By combining information on the hazard of a nano object with an qualitative inhalation exposure assessment a user of Stoffenmanager nano will get an indication of potential health risks in thee categories: high – medium or low. Stoffenmanager Nano is being developed by Arbo Unie (Henri Heussen), BECO (Michel van Wijk) and TNO Quality of Life (Maikel van Niftrik)
Target group and/or beneficiaries	SME working with manufactured nano objects
Events-opportunities for furthering the project	Dutch symposium for occupational hygiene 2010, Woudschoten, the Netherlands; 6th International Control Banding Workshop (6ICBW) on 27 September 2010 at the Urbania University in Rome, Italy; IOHA Rome 2010; Nanosafe congres, October 2010, France
Expected results of this project by 2012 (outcomes)	Release of version 1.0. of the website (Oct 2010) Report Scientific paper Stoffenmanager Nano version 2.0
Indicators of achievement (impact)	Amount of registered users Regular user evaluation indicating a customer satisfaction of 4 out of 5. A SME user of Stoffenmanager Nano is able to: generate a complete and reliable risk inventarisation and evaluation of x % of its substances, and interpret the results of the evaluation in a correct manner Apply correct control measures based on the outcome of the risk evaluation.
Major Milestones (list up to three dates and milestones)	Sept 2010 – company evaluation of beta version of STM 4.5. Oct 2010 – release of STM Nano First half 2011 – report conclusions on customer evaluation
Public health impact	Health improvement of workers exposed to manufactured nano objects. Illness prevention due to reduced inhalation exposure to manufactured nano objects.
Funding source(s)	Dutch Ministry of Social Affairs and Employment
Dissemination	Scientific papers Publications in HSE magazines Through Stoffenmanager newsletter Presentations and workshops at national and international (scientific) meetings

2009-2012 Work Plan Number	4.22m New Project
PROJECT Title	Sustainability and risk management for occupational safety – part 3 industrial hygiene
GPA Objective and GPA Action	GPA 4
Priority Number (e.g. 5.3-1) and Area (if applicable) e.g Agriculture	4.2
This project also contributes to other GPA Priorities	GPA4, priority 4.1 GPA5, priority 5.3
Responsible CC or NGO Name	IEA Sub-committee « Sustainability and risk management » (Directed by S. Nadeau and B. Ateme-Nguema, Canada) of the “Human Factors and Sustainable Development » technical committee of the International Ergonomics Association (IEA) directed by K.J. Zink (U. de Kaiserslautern - Germany) et C.G. Drury (U. Buffalo – USA): www.iea.cc
Project leader(s) (contact name and email address)	S. Hallé, Eng.Jr., Ph.D. (ÉTS) F. Morency, K. Maghni (U. de Montréal) École de technologie supérieure (ÉTS) 1100 Notre-Dame West Montreal, Quebec, Canada, H3C 1K3 http://www.etsmtl.ca/zone2/recherche/labo/erest/ [e-mail]
Network partners (CC name, country, email)	IRSST (CC under designation) G. Truchon (IRSST), Y. Cloutier (IRSST), J. Lavoie (Institut de recherche Robert Sauvé en santé et en sécurité du travail- IRSST)
WHO Regions involved in this project (contact name and email)	Pan American Health Organization (PAHO)-Canada Expertise: occupational injury prevention and risk assessment Objectives: S03-S013 EURO –Germany and France
Country ministries involved in this project (contact name and email)	Commission de la santé et de la sécurité du travail du Québec (CSST) Développement économique, innovation et exportation (MDEIE) Commission des partenaires du marché du travail (Gouvernement du Québec)
External partners for this project (contact name, organization and email)	K. Maghni (Hôpital Sacré-Cœur de Montréal-HSC) TITNT «The International Team in NanosafeTy» directed by S. Hallé, K. Maghni and C. Emond, Canada: www.titnt.com O. Joliette (U. Michigan-USA), S. Hirano (National Institute for Environmental Studies, Japan), F. Schuster (Commissariat à l’Énergie Atomique-France), C. Rolando (U. Lille-France), A. Meyer-Plath (BAM-Germany) CSST, RRSSTQ, HSC, Ordre des ingénieurs du Québec (OIQ), Dessau Soprin
Summary of the project (max 100 words)	This project will Study thermo-ventilation movements within buildings, with the aim of developing optimal ventilation strategies to improve air quality, thermal comfort and bio-safety. Study effects on health and means of controlling nano-aerosols and nanoparticles. More specifically, study the aerodynamic behaviour of nanoparticles (NPs), demonstrate the pulmonary toxicity of these particles through cellular models, and develop a model for the management of risks taking into account the strategic behaviours of stakeholders.
Target group and/or beneficiaries	mining industry, manufacturing industry, aeronautic industry, hospitals.
Major Milestones (list up to three dates and milestones)	April 2011 Develop a thermo-ventilation model of a bronchoscopy unit Jan 2012 Develop an aerodynamic behavior model for nanoparticles produced during a manufacturing process April 2012 Develop a flexible and dynamic tool for compiling and sharing detailed knowledge of the health risks associated with engineered nanoparticles
Dissemination plan	WHO publications Scientific journals the top journals in ergonomics and human factors; Journal of Occupational and Environmental Hygiene. related journals with a relatively high impact factor; Advances in Fluid Mechanics VII; basic journals with a relatively high impact factor European Journal of Immunology. Scientific conferences IEA; Gesellschaft für Arbeitswissenschaft; Nordic ergonomics society (NES); Human Factors and Ergonomics Society Annual Meeting; RRSSTQ; Association québécoise pour l’hygiène, la santé et la sécurité du travail (AQHSST); Colloque interuniversitaire franco-québécois sur la thermique des systèmes; International Conference on Advances in Fluid Mechanics; International Conference on Nanotechnology: Fundamentals and Applications; Practice communities : journals and conferences Travail et santé; ÉREST-RRSSTQ conferences (ÉREST is in charge of a community of practice of 350 members); MBA-managers (UQAT) conferences.
Funding source(s)	RRSSTQ, Fonds de la recherche en santé du Québec (FRSQ), Fonds de recherche sur la société et la culture (FQRSC), Fonds québécois de la recherche sur la nature et les technologies (FQRNT), IRSST, NanoQuébec, Développement économique, innovation et exportation (MDEIE), Commission des partenaires du marché du travail (Gouvernement du Québec), Canadian Institute of Health Research (CIHR), Natural Sciences and Engineering Research Council (NSERC), Canada Foundation for Innovation (FCI), U. du Québec, HSCM, ÉTS, CSST, Agence française de sécurité sanitaire de l’environnement et du travail (AFSSET)
List of outcomes already achieved by this project	We have already developed : A model of airborne nanoparticles transport and dispersion in an animal exposure chamber; A model of thermo-ventilation movements within buildings; A test based on basophilic strand for early identification of allergic sensitization leading to occupational asthma.
List of additional outcomes expected from this project by 2012	Based on #1 in above section, models of airborne nanoparticles transport and dispersion in high speed machining, and in spray-atomization process An improved model as in #2 of above section Airway risk assessment of TiO2, quantum wells, multi-walled carbon nanotubes; An improved test as in #3 above
List of additional outcomes expected by 2016