Table 1: International Narrative Systematic Assessment (insa) tool for assessing scientific methodological quality of reviews

Table 1: International Narrative Systematic Assessment (INSA) tool for assessing scientific methodological quality of reviews.^*

Items	Response
	Yes	No
Background of the study clearly explained / state of the art
Objective is clear
Description/Motivation of selection of studies
Description of study the characteristics included is clear
Presentation of results (paragraphs, tables, synthezing of data)
Conclusion is clear
Conflict of interest is stated (if existing and if no statement bad)

* La Torre G, Backhaus I, Mannocci A. Rating for narrative reviews: Concept and development of the international narrative systematic assessment tool. Senses Sci. 2015;2(2):31-35.

Table 2: A MeaSurement Tool to Assess systematic Reviews (AMSTAR-2) tool for assessing scientific methodological quality of systematic review and meta-analysis¹

Items	Response
	Yes	No	Partially yes OR without meta-analysis
Research questions and inclusion criteria include the components of PICO
Register the review protocol*
Justify selection of the study designs for inclusion in the review
Perform comprehensive literature search strategy*
Perform study selection in duplicate
Perform data extraction in duplicate
Provide a list of excluded studies and justify the exclusions*
Describe the included studies in adequate detail*
Use satisfactory technique for assessing the risk of bias (RoB)*
Report sources of funding for the primary studies included in the review
Use appropriate methods for statistical combination of results^£
Assess the potential impact of RoB in individual studies^£
Account for RoB in individual studies when interpreting/ discussing the results of the review
Provide a satisfactory explanation for any heterogeneity
Adequate investigation of publication bias and discuss its likely impact^£
Report conflict of interest

* with additional ‘partially yes’ option

^£ with additional ‘no meta-analysis done’ option

¹Shea BJ, Reeves BC, Wells G, Thuku M, Hamel C, Moran J, Moher D, Tugwell P, Welch V, Kristjansson E, Henry DA. AMSTAR 2: a critical appraisal tool for systematic reviews that include randomised or non-randomised studies of healthcare interventions, or both. BMJ. 2017 Sep 21;358:j4008

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