Main professor: Dr. Gilles Lemercier (University of Reims Champagne-Ardenne)
Dr. Gilles Lemercier
http://www.univ-reims.fr/rubrique-cachee/laboratoires-labelises/icmr/les-groupes-de-recherche/groupe-chimie-de-coordination,9951.html
Objectives: The aim of this course is to present the use of physical properties (magnetic and optical) of coordination complexes in biology (imagery and therapy). This course will also focus on the interests of the related nanoparticles, for a fundamental point of view but also for applications leading to confined effect and targeting.
Outlines:
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Physical properties and biological applications of molecular compounds
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Optical properties of coordination complexes
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Magnetic properties of coordination complexes
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Applications in optical and/or magnetic imagery
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Applications in therapy
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Hybrid materials and nano-cargos : from vectorisation of a chemical molecule to a physical strength
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Physical properties
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Interests in biology
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Fonctionnalization of nanoparticles
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Internal surface fonctionnalization of silica nanoparticles – MOF
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Hyperthermy and iron oxides
Prerequisites: Coordination chemistry ò the transition metals – ligand field theory – UV-vis spectroscopy
Total number of hours: 22.5 (3.5 ECTS)
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C106: Bimolecular Systems
Main professor: Dr. Thanh Ha Duong (University Paris Diderot, Paris 7)
Dr. Thanh Ha Duong
http://www.chimie.univ-paris-diderot.fr/en/directory/itodys/nguyet-thanh-aka-thanh-ha-duong-en
Objectives: The physicochemical aspect of the structure of biological macromolecules (DNA, protein, membrane ...) will be studied, focusing on the interactions responsible for the 3D organization of these biomolecules. Based on the properties of these molecules, some tools and techniques will be described. The techniques of extraction, purification and characterization of proteins will be more developed.
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