An assessment of nucleic acid amplification testing for active mycobacterial infection



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tarix04.01.2022
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Rationale for assessment


Douglass Hanly Moir Pathology Pty Ltd submitted an application to the Department of Health to create new MBS item(s) for NAAT to diagnose: (1) Mycobacterium tuberculosis (MTB) infections in persons with clinical signs and symptoms of tuberculosis (TB) or (2) non-tuberculous mycobacteria (NTM) infection in patients who have tissue biopsies with histopathology consistent with an NTM infection.

It should be noted that the NTM population eligible for NAAT has been expanded from the population specified in the protocol, in order to include all patients suspected of having an NTM infection. The expanded population base was necessary due to the the insufficient evidence-base for NTM infections as a whole. There was also value in including information on patients with specimen types other than tissue biopsies, such as HIV-positive patients presenting with M. avium complex (MAC) disease or patients with disseminated bacteraemia.



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